JPS4916435B1 - - Google Patents
Info
- Publication number
- JPS4916435B1 JPS4916435B1 JP3545969A JP3545969A JPS4916435B1 JP S4916435 B1 JPS4916435 B1 JP S4916435B1 JP 3545969 A JP3545969 A JP 3545969A JP 3545969 A JP3545969 A JP 3545969A JP S4916435 B1 JPS4916435 B1 JP S4916435B1
- Authority
- JP
- Japan
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/12—Triazine radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Biotechnology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CS339968 | 1968-05-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| JPS4916435B1 true JPS4916435B1 (ja) | 1974-04-22 |
Family
ID=5373920
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP3545969A Pending JPS4916435B1 (ja) | 1968-05-08 | 1969-05-08 |
Country Status (12)
| Country | Link |
|---|---|
| JP (1) | JPS4916435B1 (ja) |
| AT (1) | AT306930B (ja) |
| BE (1) | BE732268A (ja) |
| BR (1) | BR6908600D0 (ja) |
| CA (1) | CA921904A (ja) |
| CH (1) | CH527207A (ja) |
| DE (1) | DE1922702A1 (ja) |
| ES (1) | ES366910A1 (ja) |
| FR (1) | FR2008048A1 (ja) |
| GB (1) | GB1227691A (ja) |
| IT (1) | IT1037009B (ja) |
| NL (1) | NL6906909A (ja) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2012888C3 (de) * | 1970-03-14 | 1981-04-02 | Schering Ag, 1000 Berlin Und 4619 Bergkamen | Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden |
| US6905669B2 (en) | 2001-04-24 | 2005-06-14 | Supergen, Inc. | Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase |
| US6982253B2 (en) | 2002-06-05 | 2006-01-03 | Supergen, Inc. | Liquid formulation of decitabine and use of the same |
| US7038038B2 (en) | 2003-03-17 | 2006-05-02 | Pharmion Corporation | Synthesis of 5-azacytidine |
| US6943249B2 (en) | 2003-03-17 | 2005-09-13 | Ash Stevens, Inc. | Methods for isolating crystalline Form I of 5-azacytidine |
| US6887855B2 (en) * | 2003-03-17 | 2005-05-03 | Pharmion Corporation | Forms of 5-azacytidine |
| US20060014949A1 (en) * | 2004-07-13 | 2006-01-19 | Supergen Inc. | Compositions and formulations of decitabine polymorphs and methods of use thereof |
| US7250416B2 (en) | 2005-03-11 | 2007-07-31 | Supergen, Inc. | Azacytosine analogs and derivatives |
| US7700567B2 (en) | 2005-09-29 | 2010-04-20 | Supergen, Inc. | Oligonucleotide analogues incorporating 5-aza-cytosine therein |
| EP2073807A1 (en) | 2006-10-12 | 2009-07-01 | Astex Therapeutics Limited | Pharmaceutical combinations |
| US8916552B2 (en) | 2006-10-12 | 2014-12-23 | Astex Therapeutics Limited | Pharmaceutical combinations |
| MX363023B (es) | 2008-05-15 | 2019-03-05 | Celgene Corp | Formulaciones orales de analogos de citidina y metodos para usar los mismos. |
| ES2487525T3 (es) | 2008-08-08 | 2014-08-21 | Scinopharm Taiwan Ltd. | Procedimiento para preparar nucleósidos de 5-azacitosina y sus derivados |
| RU2013148580A (ru) | 2011-03-31 | 2015-05-10 | Селджин Интернешнл Сарл | Синтез 5-азацитидина |
| MX359314B (es) | 2011-08-30 | 2018-09-25 | Astex Pharmaceuticals Inc Star | Formulaciones derivadas de decitabina. |
| RU2723590C2 (ru) | 2015-07-02 | 2020-06-16 | Оцука Фармасьютикал Ко., Лтд. | Лиофилизированные фармацевтические композиции |
| WO2017090264A1 (ja) | 2015-11-27 | 2017-06-01 | 大原薬品工業株式会社 | ５－アザシチジン又は其の２'－デオキシ体の５'位ジベンジル燐酸エステル |
| JP6162349B1 (ja) | 2016-04-21 | 2017-07-12 | 大原薬品工業株式会社 | ５−アザシチジン類の糖部シリルエーテル誘導体 |
| US10227374B2 (en) | 2016-04-21 | 2019-03-12 | Ohara Pharmaceutical Co., Ltd. | Silyl etherified derivatives of 5-azacytidines in carbohydrate moiety |
| WO2017183215A1 (ja) | 2016-04-21 | 2017-10-26 | 大原薬品工業株式会社 | ５－アザシチジン類の糖部シリルエーテル誘導体 |
| KR20200035438A (ko) | 2017-08-03 | 2020-04-03 | 오쓰까 세이야꾸 가부시키가이샤 | 약물 화합물 및 이의 정제 방법 |
-
1969
- 1969-04-23 CH CH619669A patent/CH527207A/de not_active IP Right Cessation
- 1969-04-24 GB GB1227691D patent/GB1227691A/en not_active Expired
- 1969-04-29 BE BE732268D patent/BE732268A/xx unknown
- 1969-04-29 IT IT1620369A patent/IT1037009B/it active
- 1969-05-03 DE DE19691922702 patent/DE1922702A1/de active Pending
- 1969-05-06 NL NL6906909A patent/NL6906909A/xx unknown
- 1969-05-07 ES ES366910A patent/ES366910A1/es not_active Expired
- 1969-05-07 FR FR6914547A patent/FR2008048A1/fr active Pending
- 1969-05-07 BR BR20860069A patent/BR6908600D0/pt unknown
- 1969-05-07 AT AT439269A patent/AT306930B/de not_active IP Right Cessation
- 1969-05-08 CA CA050902A patent/CA921904A/en not_active Expired
- 1969-05-08 JP JP3545969A patent/JPS4916435B1/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CA921904A (en) | 1973-02-27 |
| GB1227691A (ja) | 1971-04-07 |
| CH527207A (de) | 1972-08-31 |
| FR2008048A1 (ja) | 1970-01-16 |
| ES366910A1 (es) | 1971-03-16 |
| AT306930B (de) | 1973-04-25 |
| IT1037009B (it) | 1979-11-10 |
| DE1922702A1 (de) | 1969-11-20 |
| BR6908600D0 (pt) | 1973-02-22 |
| BE732268A (ja) | 1969-10-01 |
| NL6906909A (ja) | 1969-11-11 |