IT1037009B - Progesso per la produzione di i glicosil 5 azacitosine - Google Patents

Progesso per la produzione di i glicosil 5 azacitosine

Info

Publication number
IT1037009B
IT1037009B IT1620369A IT1620369A IT1037009B IT 1037009 B IT1037009 B IT 1037009B IT 1620369 A IT1620369 A IT 1620369A IT 1620369 A IT1620369 A IT 1620369A IT 1037009 B IT1037009 B IT 1037009B
Authority
IT
Italy
Prior art keywords
azacitosines
progess
glycosyl
production
Prior art date
Application number
IT1620369A
Other languages
English (en)
Original Assignee
Ceskoslovenska Akademie Ved
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ceskoslovenska Akademie Ved filed Critical Ceskoslovenska Akademie Ved
Application granted granted Critical
Publication of IT1037009B publication Critical patent/IT1037009B/it

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/12—Triazine radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT1620369A 1968-05-08 1969-04-29 Progesso per la produzione di i glicosil 5 azacitosine IT1037009B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CS339968 1968-05-08

Publications (1)

Publication Number Publication Date
IT1037009B true IT1037009B (it) 1979-11-10

Family

ID=5373920

Family Applications (1)

Application Number Title Priority Date Filing Date
IT1620369A IT1037009B (it) 1968-05-08 1969-04-29 Progesso per la produzione di i glicosil 5 azacitosine

Country Status (12)

Country Link
JP (1) JPS4916435B1 (it)
AT (1) AT306930B (it)
BE (1) BE732268A (it)
BR (1) BR6908600D0 (it)
CA (1) CA921904A (it)
CH (1) CH527207A (it)
DE (1) DE1922702A1 (it)
ES (1) ES366910A1 (it)
FR (1) FR2008048A1 (it)
GB (1) GB1227691A (it)
IT (1) IT1037009B (it)
NL (1) NL6906909A (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2012888C3 (de) * 1970-03-14 1981-04-02 Schering Ag, 1000 Berlin Und 4619 Bergkamen Verfahren zur Herstellung von 5-Azapyrimidinnucleosiden
US6905669B2 (en) 2001-04-24 2005-06-14 Supergen, Inc. Compositions and methods for reestablishing gene transcription through inhibition of DNA methylation and histone deacetylase
US6982253B2 (en) 2002-06-05 2006-01-03 Supergen, Inc. Liquid formulation of decitabine and use of the same
US6943249B2 (en) 2003-03-17 2005-09-13 Ash Stevens, Inc. Methods for isolating crystalline Form I of 5-azacytidine
US6887855B2 (en) 2003-03-17 2005-05-03 Pharmion Corporation Forms of 5-azacytidine
US7038038B2 (en) 2003-03-17 2006-05-02 Pharmion Corporation Synthesis of 5-azacytidine
US20060014949A1 (en) * 2004-07-13 2006-01-19 Supergen Inc. Compositions and formulations of decitabine polymorphs and methods of use thereof
US7250416B2 (en) 2005-03-11 2007-07-31 Supergen, Inc. Azacytosine analogs and derivatives
US7700567B2 (en) 2005-09-29 2010-04-20 Supergen, Inc. Oligonucleotide analogues incorporating 5-aza-cytosine therein
WO2008044041A1 (en) 2006-10-12 2008-04-17 Astex Therapeutics Limited Pharmaceutical combinations
JP5528807B2 (ja) 2006-10-12 2014-06-25 アステックス、セラピューティックス、リミテッド 複合薬剤
US8846628B2 (en) 2008-05-15 2014-09-30 Celgene Corporation Oral formulations of cytidine analogs and methods of use thereof
CA2733591C (en) 2008-08-08 2016-06-28 Scinopharm Taiwan Ltd. Process for making 5-azacytosine nucleosides and their derivatives
BR112013025167A2 (pt) 2011-03-31 2019-09-24 Celgene Int Sarl processo para preparar 5-azacitidina, ou um sal, solvato, hidrato, ou seu polimorfo, sal de 5-azacitidina, 5-azacitidina, ou um sal, solvato, hidrato, ou polimorfo
MX359314B (es) 2011-08-30 2018-09-25 Astex Pharmaceuticals Inc Star Formulaciones derivadas de decitabina.
EP3316685A4 (en) 2015-07-02 2019-03-13 Otsuka Pharmaceutical Co., Ltd. Lyophilized Pharmaceutical Compositions
WO2017090264A1 (ja) 2015-11-27 2017-06-01 大原薬品工業株式会社 ５－アザシチジン又は其の２'－デオキシ体の５'位ジベンジル燐酸エステル
WO2017183215A1 (ja) 2016-04-21 2017-10-26 大原薬品工業株式会社 ５－アザシチジン類の糖部シリルエーテル誘導体
US10227374B2 (en) 2016-04-21 2019-03-12 Ohara Pharmaceutical Co., Ltd. Silyl etherified derivatives of 5-azacytidines in carbohydrate moiety
JP6162349B1 (ja) 2016-04-21 2017-07-12 大原薬品工業株式会社 ５−アザシチジン類の糖部シリルエーテル誘導体
JP2020529409A (ja) 2017-08-03 2020-10-08 大塚製薬株式会社 薬物化合物およびその精製方法

Also Published As

Publication number Publication date
ES366910A1 (es) 1971-03-16
FR2008048A1 (it) 1970-01-16
CH527207A (de) 1972-08-31
NL6906909A (it) 1969-11-11
JPS4916435B1 (it) 1974-04-22
AT306930B (de) 1973-04-25
DE1922702A1 (de) 1969-11-20
GB1227691A (it) 1971-04-07
BR6908600D0 (pt) 1973-02-22
BE732268A (it) 1969-10-01
CA921904A (en) 1973-02-27

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