JPH11514877A - 機能性ランゲルハンス島のインビトロ成長およびそのインビボの使用 - Google Patents

機能性ランゲルハンス島のインビトロ成長およびそのインビボの使用

Info

Publication number
JPH11514877A
JPH11514877A JP9516734A JP51673497A JPH11514877A JP H11514877 A JPH11514877 A JP H11514877A JP 9516734 A JP9516734 A JP 9516734A JP 51673497 A JP51673497 A JP 51673497A JP H11514877 A JPH11514877 A JP H11514877A
Authority
JP
Japan
Prior art keywords
cells
pancreatic
islet
cell
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
JP9516734A
Other languages
English (en)
Japanese (ja)
Inventor
ペック，アモン，ビー．
ジー． コーネリウス，ジャネット
Original Assignee
ユニバーシティ オブ フロリダ リサーチ ファウンデイション，インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/547,746 external-priority patent/US6001647A/en
Application filed by ユニバーシティ オブ フロリダ リサーチ ファウンデイション，インコーポレイテッド filed Critical ユニバーシティ オブ フロリダ リサーチ ファウンデイション，インコーポレイテッド
Publication of JPH11514877A publication Critical patent/JPH11514877A/ja
Ceased legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP9516734A 1995-10-25 1996-10-23 機能性ランゲルハンス島のインビトロ成長およびそのインビボの使用 Ceased JPH11514877A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/547,746 1995-10-25
US08/547,746 US6001647A (en) 1994-04-28 1995-10-25 In vitro growth of functional islets of Langerhans and in vivo uses thereof
PCT/US1996/016952 WO1997015310A1 (fr) 1995-10-25 1996-10-23 Croissance in vitro d'ilots de langerhans fonctionnels et utilisations in vivo de ces ilots

Publications (1)

Publication Number Publication Date
JPH11514877A true JPH11514877A (ja) 1999-12-21

Family

ID=24185961

Family Applications (1)

Application Number Title Priority Date Filing Date
JP9516734A Ceased JPH11514877A (ja) 1995-10-25 1996-10-23 機能性ランゲルハンス島のインビトロ成長およびそのインビボの使用

Country Status (5)

Country Link
EP (1) EP0871455A4 (fr)
JP (1) JPH11514877A (fr)
AU (1) AU739771B2 (fr)
CA (1) CA2235509A1 (fr)
WO (1) WO1997015310A1 (fr)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2002088335A1 (ja) * 2001-04-24 2004-08-19 味の素株式会社 幹細胞及びその分離方法
WO2007039986A1 (fr) * 2005-10-05 2007-04-12 Osaka University Procédé d'obtention de cellules endocrines pancréatiques à partir de cellules provenant d'un tissu adipeux
JP2007520194A (ja) * 2003-06-20 2007-07-26 ブレイエ・ユニバージテイト・ブリュッセル 外分泌膵臓細胞から、膵島ベータ−細胞を生成する方法
JP2022105712A (ja) * 2016-04-19 2022-07-14 凸版印刷株式会社 被検化合物の脈管新生阻害活性の評価方法

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2359821A1 (fr) * 1999-02-04 2000-08-10 Mcgill University Plate-forme de differenciation cellulaire
GB9914890D0 (en) * 1999-06-25 1999-08-25 Univ Buckingham Methods and compositions relating to pancreatic islet and -cell dysfunction
EP1224259A4 (fr) * 1999-09-27 2005-04-27 Univ Florida Inversion de diabetes dependant de l'insuline par des cellules souches insulaires, des cellules insulaires progenitrices et des structures de type insulaire
WO2001032839A2 (fr) * 1999-10-29 2001-05-10 Mcgill University Milieu servant a la preparation de cellules dedifferenciees
US20030082155A1 (en) 1999-12-06 2003-05-01 Habener Joel F. Stem cells of the islets of langerhans and their use in treating diabetes mellitus
US6866843B2 (en) 1999-12-06 2005-03-15 Viacell, Inc. Method of transplanting in a mammal and treating diabetes mellitus by administering a pseudo-islet like aggregate differentiated from a nestin-positive pancreatic stem cell
AU778155B2 (en) * 1999-12-13 2004-11-18 Scripps Research Institute, The Markers for identification and isolation of pancreatic islet alpha and beta cell progenitors
US6610535B1 (en) * 2000-02-10 2003-08-26 Es Cell International Pte Ltd. Progenitor cells and methods and uses related thereto
US6436704B1 (en) * 2000-04-10 2002-08-20 Raven Biotechnologies, Inc. Human pancreatic epithelial progenitor cells and methods of isolation and use thereof
AU2001273108A1 (en) * 2000-06-30 2002-01-14 Amcyte, Inc. Culturing pancreatic stem cells having a specified, intermediate stage of development
US7202080B2 (en) 2001-03-29 2007-04-10 Ixion Biotechnology, Inc. Method for transdifferentiation of non-pancreatic stem cells to the pancreatic differentiation pathway
US7101546B2 (en) 2001-12-21 2006-09-05 Amcyte, Inc. In situ maturation of cultured pancreatic stem cells having a specified, intermediate stage of development
EP1539928A4 (fr) 2002-09-06 2006-09-06 Amcyte Inc Cellules progenitrices endocrines pancreatiques positives cd56 chez l'etre humain adulte
EP1629089A1 (fr) * 2003-06-03 2006-03-01 Organ Recovery Systems, Inc. Selection et propagation de cellules progenitrices
US20060121512A1 (en) * 2004-12-02 2006-06-08 Organ Recovery Systems, Inc. Biological pathways in progenitor cells
KR101452877B1 (ko) * 2013-08-05 2014-10-22 사회복지법인 삼성생명공익재단 조기-내피전구세포 및 췌도세포를 포함하는 세포이식물의 제조방법

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK0605428T5 (da) * 1991-06-24 2003-01-06 Hcell Technology Inc Hormonsecernerende pancreasceller opretholdt i langtidskultur
JP2813467B2 (ja) * 1993-04-08 1998-10-22 ヒューマン・セル・カルチャーズ・インコーポレーテッド 細胞培養法および培地
US5834308A (en) * 1994-04-28 1998-11-10 University Of Florida Research Foundation, Inc. In vitro growth of functional islets of Langerhans

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPWO2002088335A1 (ja) * 2001-04-24 2004-08-19 味の素株式会社 幹細胞及びその分離方法
JP2007520194A (ja) * 2003-06-20 2007-07-26 ブレイエ・ユニバージテイト・ブリュッセル 外分泌膵臓細胞から、膵島ベータ−細胞を生成する方法
WO2007039986A1 (fr) * 2005-10-05 2007-04-12 Osaka University Procédé d'obtention de cellules endocrines pancréatiques à partir de cellules provenant d'un tissu adipeux
JP5131833B2 (ja) * 2005-10-05 2013-01-30 晃文 松山 脂肪組織由来細胞から膵内分泌細胞を得る方法
JP2022105712A (ja) * 2016-04-19 2022-07-14 凸版印刷株式会社 被検化合物の脈管新生阻害活性の評価方法

Also Published As

Publication number Publication date
MX9803263A (es) 1998-09-30
CA2235509A1 (fr) 1997-05-01
AU739771B2 (en) 2001-10-18
EP0871455A4 (fr) 2003-05-14
AU7468396A (en) 1997-05-15
WO1997015310A1 (fr) 1997-05-01
EP0871455A1 (fr) 1998-10-21

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JPH11514877A (ja) 機能性ランゲルハンス島のインビトロ成長およびそのインビボの使用
US20080274090A1 (en) Reversal of insulin-dependent diabetes by islet-producing stem cells, islet progenitor cells and islet-like structures
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