AU739771B2 - In vitro growth of functional islets of langerhans and in vivo uses thereof - Google Patents

In vitro growth of functional islets of langerhans and in vivo uses thereof Download PDF

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Publication number
AU739771B2
AU739771B2 AU74683/96A AU7468396A AU739771B2 AU 739771 B2 AU739771 B2 AU 739771B2 AU 74683/96 A AU74683/96 A AU 74683/96A AU 7468396 A AU7468396 A AU 7468396A AU 739771 B2 AU739771 B2 AU 739771B2
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AU
Australia
Prior art keywords
cells
islet
cell
culture
pancreatic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
AU74683/96A
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English (en)
Other versions
AU7468396A (en
Inventor
Janet G Cornelius
Ammon B Peck
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Florida Research Foundation Inc
Original Assignee
University of Florida
University of Florida Research Foundation Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/547,746 external-priority patent/US6001647A/en
Application filed by University of Florida, University of Florida Research Foundation Inc filed Critical University of Florida
Publication of AU7468396A publication Critical patent/AU7468396A/en
Application granted granted Critical
Publication of AU739771B2 publication Critical patent/AU739771B2/en
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0676—Pancreatic cells
    • C12N5/0678—Stem cells; Progenitor cells; Precursor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Diabetes (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Obesity (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Developmental Biology & Embryology (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
AU74683/96A 1995-10-25 1996-10-23 In vitro growth of functional islets of langerhans and in vivo uses thereof Ceased AU739771B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US08/547746 1995-10-25
US08/547,746 US6001647A (en) 1994-04-28 1995-10-25 In vitro growth of functional islets of Langerhans and in vivo uses thereof
PCT/US1996/016952 WO1997015310A1 (fr) 1995-10-25 1996-10-23 Croissance in vitro d'ilots de langerhans fonctionnels et utilisations in vivo de ces ilots

Related Child Applications (1)

Application Number Title Priority Date Filing Date
AU10195/02A Division AU1019502A (en) 1995-10-25 2002-01-16 In vitro growth of functional islets of langerhans and in vivo uses thereof

Publications (2)

Publication Number Publication Date
AU7468396A AU7468396A (en) 1997-05-15
AU739771B2 true AU739771B2 (en) 2001-10-18

Family

ID=24185961

Family Applications (1)

Application Number Title Priority Date Filing Date
AU74683/96A Ceased AU739771B2 (en) 1995-10-25 1996-10-23 In vitro growth of functional islets of langerhans and in vivo uses thereof

Country Status (5)

Country Link
EP (1) EP0871455A4 (fr)
JP (1) JPH11514877A (fr)
AU (1) AU739771B2 (fr)
CA (1) CA2235509A1 (fr)
WO (1) WO1997015310A1 (fr)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1144595A2 (fr) * 1999-02-04 2001-10-17 McGILL UNIVERSITY Plate-forme de differenciation cellulaire
GB9914890D0 (en) * 1999-06-25 1999-08-25 Univ Buckingham Methods and compositions relating to pancreatic islet and -cell dysfunction
CA2385628A1 (fr) * 1999-09-27 2001-04-05 Ammon B. Peck Inversion de diabetes dependant de l'insuline par des cellules souches insulaires, des cellules insulaires progenitrices et des structures de type insulaire
IL149290A0 (en) * 1999-10-29 2002-11-10 Univ Mcgill Medium for preparing dedifferentiated cells
WO2001039784A1 (fr) 1999-12-06 2001-06-07 The General Hospital Corporation Cellules souches pancreatiques et leur utilisation en transplantation
US20030082155A1 (en) 1999-12-06 2003-05-01 Habener Joel F. Stem cells of the islets of langerhans and their use in treating diabetes mellitus
US6753153B2 (en) * 1999-12-13 2004-06-22 The Scripps Research Institute Markers for identification and isolation of pancreatic islet α and β progenitors
US6610535B1 (en) * 2000-02-10 2003-08-26 Es Cell International Pte Ltd. Progenitor cells and methods and uses related thereto
US6436704B1 (en) 2000-04-10 2002-08-20 Raven Biotechnologies, Inc. Human pancreatic epithelial progenitor cells and methods of isolation and use thereof
CA2415108A1 (fr) * 2000-06-30 2002-01-10 Amcyte, Inc. Culture de cellules embryonnaires pancreatiques presentant un stade de developpement intermediaire specifie
CA2442177A1 (fr) 2001-03-29 2002-10-10 Ixion Biotechnology, Inc. Procede de transdifferentiation de cellules souches non pancreatiques dans la voie de differentiation du pancreas
ATE421991T1 (de) * 2001-04-24 2009-02-15 Ajinomoto Kk Stammzellen und verfahren zu deren trennung
US7101546B2 (en) 2001-12-21 2006-09-05 Amcyte, Inc. In situ maturation of cultured pancreatic stem cells having a specified, intermediate stage of development
US7371576B2 (en) 2002-09-06 2008-05-13 Reneuron, Inc. CD56 positive human adult pancreatic endocrine progenitor cells
WO2004108910A1 (fr) * 2003-06-03 2004-12-16 Organ Recovery Systems, Inc. Selection et propagation de cellules progenitrices
ES2330438T3 (es) * 2003-06-20 2009-12-10 Vrije Universiteit Brussel Vub Procedimiento de generacion de celulas beta de islotes de langerhans a partir de celulas pancreaticas exocrinas.
US20060121512A1 (en) * 2004-12-02 2006-06-08 Organ Recovery Systems, Inc. Biological pathways in progenitor cells
US20100322906A1 (en) 2005-10-05 2010-12-23 Osaka University Method for Obtaining Pancreatic Endocrine Cells From Adipose Tissue-Origin Cells
KR101452877B1 (ko) * 2013-08-05 2014-10-22 사회복지법인 삼성생명공익재단 조기-내피전구세포 및 췌도세포를 포함하는 세포이식물의 제조방법
JP7081483B2 (ja) * 2016-04-19 2022-06-07 凸版印刷株式会社 被検化合物の脈管新生阻害活性の評価方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69232535D1 (de) * 1991-06-24 2002-05-08 Pacific Biomedical Res Inc In langzeitkultur gehaltene hormon-absondernde pankreatische zellen
JP2813467B2 (ja) * 1993-04-08 1998-10-22 ヒューマン・セル・カルチャーズ・インコーポレーテッド 細胞培養法および培地
US5834308A (en) * 1994-04-28 1998-11-10 University Of Florida Research Foundation, Inc. In vitro growth of functional islets of Langerhans

Also Published As

Publication number Publication date
MX9803263A (es) 1998-09-30
CA2235509A1 (fr) 1997-05-01
JPH11514877A (ja) 1999-12-21
WO1997015310A1 (fr) 1997-05-01
EP0871455A1 (fr) 1998-10-21
AU7468396A (en) 1997-05-15
EP0871455A4 (fr) 2003-05-14

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