DE60231035D1 - Stammzellen und verfahren zu deren trennung - Google Patents
Stammzellen und verfahren zu deren trennungInfo
- Publication number
- DE60231035D1 DE60231035D1 DE60231035T DE60231035T DE60231035D1 DE 60231035 D1 DE60231035 D1 DE 60231035D1 DE 60231035 T DE60231035 T DE 60231035T DE 60231035 T DE60231035 T DE 60231035T DE 60231035 D1 DE60231035 D1 DE 60231035D1
- Authority
- DE
- Germany
- Prior art keywords
- stem cell
- pancreatic stem
- mammal
- separation
- stem cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
- C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
- C12Q1/6881—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for tissue or cell typing, e.g. human leukocyte antigen [HLA] probes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0676—Pancreatic cells
- C12N5/0678—Stem cells; Progenitor cells; Precursor cells
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2503/00—Use of cells in diagnostics
- C12N2503/02—Drug screening
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q2600/00—Oligonucleotides characterized by their use
- C12Q2600/158—Expression markers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Physics & Mathematics (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Food Science & Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Pathology (AREA)
- General Physics & Mathematics (AREA)
- Tropical Medicine & Parasitology (AREA)
- Biophysics (AREA)
- Gastroenterology & Hepatology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2001126315 | 2001-04-24 | ||
PCT/JP2002/004084 WO2002088335A1 (fr) | 2001-04-24 | 2002-04-24 | Cellules souches et procede d'extraction de ces cellules |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60231035D1 true DE60231035D1 (de) | 2009-03-19 |
Family
ID=18975375
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60231035T Expired - Lifetime DE60231035D1 (de) | 2001-04-24 | 2002-04-24 | Stammzellen und verfahren zu deren trennung |
Country Status (7)
Country | Link |
---|---|
US (1) | US20050003529A1 (de) |
EP (1) | EP1391505B1 (de) |
JP (1) | JP4296781B2 (de) |
CN (1) | CN100516204C (de) |
AT (1) | ATE421991T1 (de) |
DE (1) | DE60231035D1 (de) |
WO (1) | WO2002088335A1 (de) |
Families Citing this family (42)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU2002327730A1 (en) * | 2001-09-26 | 2003-04-07 | University Of North Carolina At Chapel Hill | Variants of alpha-fetoprotein coding and expression sequences |
JP2007503815A (ja) * | 2003-08-27 | 2007-03-01 | ステムセルズ・カリフォルニア・インコーポレイテッド | 富化された膵臓幹細胞および前駆細胞集団、ならびにこれらの集団の同定、単離および富化方法 |
EP3461884A1 (de) | 2004-03-22 | 2019-04-03 | Mesoblast International Sàrl | Mesenchymale stammzellen und verwendungen davon |
US8017395B2 (en) | 2004-12-17 | 2011-09-13 | Lifescan, Inc. | Seeding cells on porous supports |
AU2006202209B2 (en) * | 2005-05-27 | 2011-04-14 | Lifescan, Inc. | Amniotic fluid derived cells |
SI1888123T1 (sl) | 2005-06-08 | 2013-04-30 | Janssen Biotech, Inc. | Celična terapija za okularno degeneracijo |
WO2007009356A1 (fr) * | 2005-07-15 | 2007-01-25 | Theracells Biotechnologies Co., Ltd. | Méthode pour détecter et cultiver des cellules pancréatiques et application |
CN1982440B (zh) * | 2005-07-15 | 2010-11-17 | 广西南宁灵康赛诺科生物科技有限公司 | 经培养的胰腺细胞及其培养方法和用途 |
US8741643B2 (en) | 2006-04-28 | 2014-06-03 | Lifescan, Inc. | Differentiation of pluripotent stem cells to definitive endoderm lineage |
US20080064098A1 (en) * | 2006-06-05 | 2008-03-13 | Cryo-Cell International, Inc. | Procurement, isolation and cryopreservation of maternal placental cells |
US20080050814A1 (en) * | 2006-06-05 | 2008-02-28 | Cryo-Cell International, Inc. | Procurement, isolation and cryopreservation of fetal placental cells |
US20080124684A1 (en) * | 2006-11-28 | 2008-05-29 | Grell Mathew L | System and method of celebration by personalizing apparel |
US9080145B2 (en) | 2007-07-01 | 2015-07-14 | Lifescan Corporation | Single pluripotent stem cell culture |
WO2009018453A1 (en) | 2007-07-31 | 2009-02-05 | Lifescan, Inc. | Differentiation of human embryonic stem cells |
CN101878298B (zh) | 2007-11-27 | 2017-08-15 | 生命扫描有限公司 | 人胚胎干细胞的分化 |
BRPI0908033A2 (pt) | 2008-02-21 | 2015-08-04 | Centocor Ortho Biotech Inc | Método placas de superfície modificada e composições para adesão, cultura e desprendimento de célula |
US8623648B2 (en) | 2008-04-24 | 2014-01-07 | Janssen Biotech, Inc. | Treatment of pluripotent cells |
PL2942392T3 (pl) | 2008-06-30 | 2019-02-28 | Janssen Biotech, Inc | Różnicowanie pluripotencjalnych komórek macierzystych |
MX349178B (es) | 2008-10-31 | 2017-07-17 | Centocor Ortho Biotech Inc | Diferenciación de células madre embrionarias humanas al linaje endocrino pancreático. |
EP2346988B1 (de) | 2008-10-31 | 2017-05-31 | Janssen Biotech, Inc. | Differenzierung menschlicher embryonaler stammzellen in die pankreatisch-endokrine linie |
MX2011005289A (es) | 2008-11-20 | 2011-06-01 | Centocor Ortho Biotech Inc | Metodos y composiciones para union y cultivo celular sobre sustratos planares. |
KR101774546B1 (ko) | 2008-11-20 | 2017-09-04 | 얀센 바이오테크 인코포레이티드 | 마이크로-캐리어 상의 만능 줄기 세포 배양 |
EP2456862A4 (de) | 2009-07-20 | 2013-02-27 | Janssen Biotech Inc | Differenzierung menschlicher embryonischer stammzellen |
CN103952372B (zh) | 2009-07-20 | 2016-10-05 | 詹森生物科技公司 | 人胚胎干细胞的分化 |
PL2456858T3 (pl) | 2009-07-20 | 2019-01-31 | Janssen Biotech, Inc | Różnicowanie ludzkich embrionalnych komórek macierzystych |
WO2011079018A2 (en) | 2009-12-23 | 2011-06-30 | Centocor Ortho Biotech Inc. | Differentiation of human embryonic stem cells |
RU2701335C2 (ru) | 2009-12-23 | 2019-09-25 | Янссен Байотек, Инк. | Способ получения популяции панкреатических эндокринных клеток, соэкспрессирующих nkx6.1 и инсулин, и способ лечения диабета |
SG183535A1 (en) | 2010-03-01 | 2012-10-30 | Janssen Biotech Inc | Methods for purifying cells derived from pluripotent stem cells |
EP2569419B1 (de) | 2010-05-12 | 2019-03-20 | Janssen Biotech, Inc. | Differenzierung menschlicher embryonischer stammzellen |
EP3372672A1 (de) | 2010-08-31 | 2018-09-12 | Janssen Biotech, Inc. | Differenzierung menschlicher embryonischer stammzellen |
EP2611910B1 (de) | 2010-08-31 | 2018-01-17 | Janssen Biotech, Inc. | Differenzierung menschlicher embryonischer stammzellen |
US9181528B2 (en) | 2010-08-31 | 2015-11-10 | Janssen Biotech, Inc. | Differentiation of pluripotent stem cells |
MX2014007744A (es) | 2011-12-22 | 2015-01-12 | Janssen Biotech Inc | Diferenciacion de celulas madre embrionicas humanas en celulas individuales positivas de insulina hormonal. |
SG11201405052RA (en) | 2012-03-07 | 2014-10-30 | Janssen Biotech Inc | Defined media for expansion and maintenance of pluripotent stem cells |
CA2875786C (en) | 2012-06-08 | 2022-12-06 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells into pancreatic endocrine cells |
EP2938722B1 (de) | 2012-12-31 | 2021-12-08 | Janssen Biotech, Inc. | Suspension und zusammenlagerung von menschlichen pluripotenten zellen zur differenzierung in endokrine pankreaszellen |
US10370644B2 (en) | 2012-12-31 | 2019-08-06 | Janssen Biotech, Inc. | Method for making human pluripotent suspension cultures and cells derived therefrom |
US10138465B2 (en) | 2012-12-31 | 2018-11-27 | Janssen Biotech, Inc. | Differentiation of human embryonic stem cells into pancreatic endocrine cells using HB9 regulators |
CN105008518B (zh) | 2012-12-31 | 2020-08-07 | 詹森生物科技公司 | 在空气-液体界面处培养人胚胎干细胞以用于分化成胰腺内分泌细胞 |
KR102162138B1 (ko) | 2014-05-16 | 2020-10-06 | 얀센 바이오테크 인코포레이티드 | 췌장 내분비 세포에서 mafa 발현을 향상시키기 위한 소분자의 용도 |
MA45479A (fr) | 2016-04-14 | 2019-02-20 | Janssen Biotech Inc | Différenciation de cellules souches pluripotentes en cellules de l'endoderme de l'intestin moyen |
CN108753685B (zh) * | 2018-06-20 | 2022-06-28 | 首都医科大学 | 一种表达c-Kit的人主动脉血管壁干细胞的分离、筛选、培养及功能鉴定方法 |
Family Cites Families (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH11514877A (ja) * | 1995-10-25 | 1999-12-21 | ユニバーシティ オブ フロリダ リサーチ ファウンデイション,インコーポレイテッド | 機能性ランゲルハンス島のインビトロ成長およびそのインビボの使用 |
DE69626034T2 (de) * | 1995-11-09 | 2003-08-14 | Takeda Chemical Industries Ltd | Zusammensetzung für verbesserung der pankreasfunktion |
JP2002507407A (ja) * | 1998-03-23 | 2002-03-12 | ザイモジェネティクス,インコーポレイティド | 心臓由来幹細胞 |
WO2000014203A1 (fr) * | 1998-09-02 | 2000-03-16 | Chugai Seiyaku Kabushiki Kaisha | Procede de preparation d'une fraction de cellule contenant des cellules souches hematopoietiques |
JP2000217576A (ja) * | 1999-02-02 | 2000-08-08 | Herikkusu Kenkyusho:Kk | 脂肪細胞への分化を誘導する方法、並びに脂肪細胞への分化を制御する化合物およびそのスクリーニング方法 |
JP2002538779A (ja) * | 1999-02-10 | 2002-11-19 | キュリス インコーポレイテッド | 膵臓細胞前駆細胞、それらに関する方法及び利用 |
JP2001086982A (ja) * | 1999-07-16 | 2001-04-03 | Shunpei Niida | 骨吸収調節薬 |
-
2002
- 2002-04-24 WO PCT/JP2002/004084 patent/WO2002088335A1/ja active Application Filing
- 2002-04-24 JP JP2002585616A patent/JP4296781B2/ja not_active Expired - Fee Related
- 2002-04-24 EP EP02720586A patent/EP1391505B1/de not_active Expired - Lifetime
- 2002-04-24 DE DE60231035T patent/DE60231035D1/de not_active Expired - Lifetime
- 2002-04-24 CN CNB028124758A patent/CN100516204C/zh not_active Expired - Fee Related
- 2002-04-24 AT AT02720586T patent/ATE421991T1/de not_active IP Right Cessation
-
2003
- 2003-10-27 US US10/693,712 patent/US20050003529A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20050003529A1 (en) | 2005-01-06 |
WO2002088335A1 (fr) | 2002-11-07 |
JPWO2002088335A1 (ja) | 2004-08-19 |
CN100516204C (zh) | 2009-07-22 |
CN1518593A (zh) | 2004-08-04 |
EP1391505A4 (de) | 2004-09-29 |
ATE421991T1 (de) | 2009-02-15 |
JP4296781B2 (ja) | 2009-07-15 |
EP1391505A1 (de) | 2004-02-25 |
EP1391505B1 (de) | 2009-01-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |