JPH11503423A - 下痢止め剤および抗潰瘍剤として使用される、ペクチンとリン脂質とを含有する医薬組成物 - Google Patents
下痢止め剤および抗潰瘍剤として使用される、ペクチンとリン脂質とを含有する医薬組成物Info
- Publication number
- JPH11503423A JPH11503423A JP8529896A JP52989696A JPH11503423A JP H11503423 A JPH11503423 A JP H11503423A JP 8529896 A JP8529896 A JP 8529896A JP 52989696 A JP52989696 A JP 52989696A JP H11503423 A JPH11503423 A JP H11503423A
- Authority
- JP
- Japan
- Prior art keywords
- mixture
- weight
- plant fiber
- drug
- diarrhea
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
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Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/75—Rutaceae (Rue family)
- A61K36/752—Citrus, e.g. lime, orange or lemon
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
- A23K10/37—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms from waste material
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/105—Aliphatic or alicyclic compounds
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/158—Fatty acids; Fats; Products containing oils or fats
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K50/00—Feeding-stuffs specially adapted for particular animals
- A23K50/30—Feeding-stuffs specially adapted for particular animals for swines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/66—Phosphorus compounds
- A61K31/683—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols
- A61K31/685—Diesters of a phosphorus acid with two hydroxy compounds, e.g. phosphatidylinositols one of the hydroxy compounds having nitrogen atoms, e.g. phosphatidylserine, lecithin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P60/00—Technologies relating to agriculture, livestock or agroalimentary industries
- Y02P60/80—Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
- Y02P60/87—Re-use of by-products of food processing for fodder production
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Engineering & Computer Science (AREA)
- Polymers & Plastics (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- Mycology (AREA)
- Animal Husbandry (AREA)
- Botany (AREA)
- Food Science & Technology (AREA)
- Biotechnology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Birds (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Physiology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.ペクチン質植物繊維物質と、リン脂質との混合物からなる、動物およびヒト における下痢および胃潰瘍の治療用薬剤であって、該薬剤が、リン脂質と混合す る前に、強力な撹拌条件下で、水の表面張力よりも著しく低い表面張力をもつ、 生理的に許容される液状有機物質を、該植物繊維物質に添加することにより得ら れることを特徴とする、上記治療用薬剤。 2.使用する該有機物質がアルコールまたはアルコール混合物であって、該有機 物質は混合後に除去されず、得られる薬剤の構成成分を形成する、請求の範囲第 1項に記載の治療用薬剤。 3.該有機物質が、ピロリドン含有化合物である、請求の範囲第1項に記載の治 療用薬剤。 4.該有機物質が、ポリビニルピロリドン(PVP)である、請求の範囲第3項に記 載の治療用薬剤。 5.該有機物質が、エトキシル化ソルビタン脂肪酸エステルである、請求の範囲 第1項に記載の治療用薬剤。 6.該ペクチン質植物繊維物質が、ポテトパルプ、柑橘類搾りカス、リンゴ搾り カス、大豆繊維から選択され、かつ該最終混合物の65〜90重量%を構成し、使用 する該アルコールがエタノールまたはエタノールとグリセロールとの混合物であ り、該植物繊維物質を基準として、該最終混合物の2〜10重量%を構成し、かつ 該リン脂質がレシチンであって、該植物繊維物質を基準として、該最終混合物の 5〜15重量%を構成する、請求項1〜5の何れか1項に記載の治療用薬剤。 7.動物およびヒトの消化管に関連する疾患の治療のための、請求の範囲第1〜 6項に記載の薬剤の使用。 8.該疾患が、哺乳動物および鳥類、好ましくは家禽、ブタおよびウシの腸管に おける、サルモネラ菌感染により発生するものである、請求の範囲第7項に記載 の使用。 9.該疾患が、ヒトを包含する哺乳動物の胃漬瘍である、請求の範囲第7項に記 載の使用。 10.動物の消化管に関連した疾患、好ましくは下痢および胃潰瘍を予防するため の飼料であって、請求の範囲第1〜6項に記載の薬剤を有効量で含有することを 特徴とする、上記飼料。 11.請求の範囲第1〜6項に記載の薬剤を、2〜10重量%含有する、請求の範囲 第10項に記載の飼料。 12.微粉砕した、乾燥ペクチン質植物繊維物質を、強力な攪拌下で、該植物繊維 物質を基準として、2〜10重量%の有機物質、好ましくは少なくとも1種のアル コールと混合し、次いで該植物繊維物質を基準として5〜15重量%の、45℃を越 える温度に加熱したレシチンを、攪拌下で添加して、均一な混合物を得ることを 特徴とする、請求の範囲第1〜6項に記載の薬剤の製造方法。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DK37695 | 1995-04-03 | ||
DK0376/95 | 1995-04-03 | ||
PCT/DK1996/000168 WO1996031239A1 (en) | 1995-04-03 | 1996-04-03 | Pharmaceutical composition containing pectin and a phospholipid, used as an antidiarrheal and antiulcer agent |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007213441A Division JP4755633B2 (ja) | 1995-04-03 | 2007-08-20 | 下痢止め剤および抗潰瘍剤として使用される、ペクチンとリン脂質とを含有する医薬組成物 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH11503423A true JPH11503423A (ja) | 1999-03-26 |
JP4290223B2 JP4290223B2 (ja) | 2009-07-01 |
Family
ID=8092806
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP52989696A Expired - Lifetime JP4290223B2 (ja) | 1995-04-03 | 1996-04-03 | 下痢止め剤および抗潰瘍剤として使用される、ペクチンとリン脂質とを含有する医薬組成物 |
JP2007213441A Expired - Lifetime JP4755633B2 (ja) | 1995-04-03 | 2007-08-20 | 下痢止め剤および抗潰瘍剤として使用される、ペクチンとリン脂質とを含有する医薬組成物 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2007213441A Expired - Lifetime JP4755633B2 (ja) | 1995-04-03 | 2007-08-20 | 下痢止め剤および抗潰瘍剤として使用される、ペクチンとリン脂質とを含有する医薬組成物 |
Country Status (11)
Country | Link |
---|---|
US (1) | US6024959A (ja) |
EP (1) | EP0820306B1 (ja) |
JP (2) | JP4290223B2 (ja) |
AT (1) | ATE228855T1 (ja) |
AU (1) | AU696539B2 (ja) |
CA (1) | CA2217191C (ja) |
DE (2) | DE69625188T2 (ja) |
DK (1) | DK0820306T3 (ja) |
ES (1) | ES2188749T3 (ja) |
NZ (1) | NZ305350A (ja) |
WO (1) | WO1996031239A1 (ja) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2346646A1 (en) * | 1998-10-06 | 2000-04-13 | Mars Uk Limited | Animal stereotypy |
JP3511952B2 (ja) * | 1999-01-19 | 2004-03-29 | 不二製油株式会社 | ペクチン及びその製造法並びにそれを使用した酸性蛋白食品及びその製造法 |
GB9905542D0 (en) * | 1999-03-10 | 1999-05-05 | Mars Uk Ltd | Pet food |
GB9926919D0 (en) * | 1999-11-15 | 2000-01-12 | Park Tonks Limited | Animal feed |
US7115298B2 (en) | 2001-12-14 | 2006-10-03 | Tropicana Products, Inc. | Dried citrus peel supplement for use in commercial poultry feed |
US10076549B2 (en) * | 2012-11-28 | 2018-09-18 | Smartpak Equine Llc | Gastric health supplement and methods thereof |
RU2694256C2 (ru) * | 2017-12-05 | 2019-07-11 | Федеральное государственное бюджетное учреждение науки Сибирский федеральный научный центр агробиотехнологий Российской академии наук (СФНЦА РАН) | Кормовая добавка для профилактики бактерионосительства микроорганизмов рода Salmonella у сельскохозяйственной птицы и способ ее применения |
CN110665002B (zh) * | 2019-10-29 | 2023-01-24 | 信阳市动物疫病预防控制中心 | 一种用于防治牛病毒性腹泻的抗体制剂及其制备方法 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4076717A (en) * | 1971-12-15 | 1978-02-28 | G. D. Searle & Co. | Derivatives of 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid |
DE2715384C3 (de) * | 1977-04-06 | 1981-10-01 | Laves-Arzneimittel Gmbh & Co Kg, 3000 Hannover | Arzneimittel gegen Diarrhöen |
US4321263A (en) * | 1980-09-30 | 1982-03-23 | Rowell Laboratories, Inc. | Psyllium compositions |
DE3374914D1 (en) * | 1982-04-12 | 1988-01-28 | Univ Texas | Methods and compositions for treating gastro-intestinal ulcer diesease |
US4551331A (en) * | 1983-06-02 | 1985-11-05 | S. C. Johnson & Son, Inc. | Easily dispersible dietary fiber product and method for producing the same |
US4666716A (en) * | 1984-09-04 | 1987-05-19 | Richardson-Vicks Inc. | Antidiarrheal compositions and use thereof |
DK153442C (da) * | 1985-10-14 | 1988-12-19 | Poul Bachmann | Middel, baseret paa pektinholdigt materiale, til behandling og forebyggelse af diarre hos mennesker og dyr |
US4999200A (en) * | 1987-12-09 | 1991-03-12 | Marion Laboratories | Psyllium tablet composition, method of manufacture and method of use |
SE466130B (sv) * | 1990-11-22 | 1992-01-07 | Kabi Pharmacia Ab | Gelbildande flytande dietfiberkomposition |
US5258181A (en) * | 1992-03-02 | 1993-11-02 | The Procter & Gamble Company | Compositions containing psyllium |
-
1996
- 1996-04-03 NZ NZ305350A patent/NZ305350A/en not_active IP Right Cessation
- 1996-04-03 CA CA2217191A patent/CA2217191C/en not_active Expired - Lifetime
- 1996-04-03 DE DE69625188T patent/DE69625188T2/de not_active Expired - Lifetime
- 1996-04-03 AT AT96909991T patent/ATE228855T1/de active
- 1996-04-03 US US08/930,569 patent/US6024959A/en not_active Expired - Lifetime
- 1996-04-03 AU AU53330/96A patent/AU696539B2/en not_active Expired
- 1996-04-03 DE DE0820306T patent/DE820306T1/de active Pending
- 1996-04-03 EP EP96909991A patent/EP0820306B1/en not_active Expired - Lifetime
- 1996-04-03 JP JP52989696A patent/JP4290223B2/ja not_active Expired - Lifetime
- 1996-04-03 ES ES96909991T patent/ES2188749T3/es not_active Expired - Lifetime
- 1996-04-03 DK DK96909991T patent/DK0820306T3/da active
- 1996-04-03 WO PCT/DK1996/000168 patent/WO1996031239A1/en active IP Right Grant
-
2007
- 2007-08-20 JP JP2007213441A patent/JP4755633B2/ja not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
JP4290223B2 (ja) | 2009-07-01 |
CA2217191C (en) | 2011-01-04 |
ATE228855T1 (de) | 2002-12-15 |
EP0820306A1 (en) | 1998-01-28 |
AU5333096A (en) | 1996-10-23 |
DK0820306T3 (da) | 2003-03-10 |
JP4755633B2 (ja) | 2011-08-24 |
DE69625188D1 (de) | 2003-01-16 |
JP2007297413A (ja) | 2007-11-15 |
ES2188749T3 (es) | 2003-07-01 |
NZ305350A (en) | 1998-07-28 |
EP0820306B1 (en) | 2002-12-04 |
US6024959A (en) | 2000-02-15 |
AU696539B2 (en) | 1998-09-10 |
WO1996031239A1 (en) | 1996-10-10 |
DE820306T1 (de) | 2001-12-20 |
DE69625188T2 (de) | 2003-07-17 |
CA2217191A1 (en) | 1996-10-10 |
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