JPH10507390A - 粒子供給装置 - Google Patents
粒子供給装置Info
- Publication number
- JPH10507390A JPH10507390A JP8513731A JP51373196A JPH10507390A JP H10507390 A JPH10507390 A JP H10507390A JP 8513731 A JP8513731 A JP 8513731A JP 51373196 A JP51373196 A JP 51373196A JP H10507390 A JPH10507390 A JP H10507390A
- Authority
- JP
- Japan
- Prior art keywords
- capsule
- chamber
- nozzle
- syringe
- particles
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/30—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules
- A61M5/3015—Syringes for injection by jet action, without needle, e.g. for use with replaceable ampoules or carpules for injecting a dose of particles in form of powdered drug, e.g. mounted on a rupturable membrane and accelerated by a gaseous shock wave or supersonic gas flow
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M35/00—Means for application of stress for stimulating the growth of microorganisms or the generation of fermentation or metabolic products; Means for electroporation or cell fusion
- C12M35/04—Mechanical means, e.g. sonic waves, stretching forces, pressure or shear stimuli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/20—Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
- A61M5/2053—Media being expelled from injector by pressurised fluid or vacuum
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Sustainable Development (AREA)
- Vascular Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Mechanical Engineering (AREA)
- Anesthesiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
Abstract
Description
Claims (1)
- 【特許請求の範囲】 1.注射針のない注射器であって、 長尺のノズル(5)にして、その上流側端部には該ノズルと軸方向に整列して 開放端部を有するカプセル室(19)が形成されて使用時には該室が治療薬剤の 粒子を包含する軟壁のカプセル(19A)を密に収容するように構成された、ノ ズル(5)と、 前記カプセル室の上流側端部に位置して該室内の前記カプセルの上流側端部を 穿通する穿通手段(21)と、 前記カプセルの穿通後、前記粒子を付勢してカプセルの下流側端部を経てカプ セル室の下流側開放端部を通過させ以て該粒子を乗せて運ぶ超音波ガス流をノズ ル(5)内に形成するに充分なガス圧を供給する加圧手段(12)と、 を備えた、 ことを特徴とする注射器。 2.ゼラチン状の壁を有すると共にドーム形の端部を有する略円筒状のカプセル (19A)を収容する、 ことを特徴とする請求の範囲第1項記載の注射器。 3.前記カプセル室(19)が、前記ノズルの軸線に垂直に分割された二つの別 個の壁部(17、18)内に形成されている、 ことを特徴とする請求の範囲第1項又は第2項記載の注射器。 4.前記室(19)の前記二つの壁部(17、18)が、取り外し可能な接続部 (6)を介して相互に連結される注射器の二つの部分(4、5)を組み付けるこ とにより、接合される、 ことを特徴とする請求の範囲第3項記載の注射器。 5.前記カプセルの上流側端部を穿通する手段が、カプセル室(19)の上流側 端部からカプセル室(19)内に突出するカッタ(21)である、 ことを特徴とする請求の範囲前記各項のいずれか一項に記載の注射器。 6.前記二つの壁部(17、18)が、カプセルを中心として軸方向に一緒に引 き寄せられるように構成されており、該二つの壁部が一緒に引き寄せられると前 記カッタ(21)がカプセルの上流側端部を穿通するように構成されている、 ことを特徴とする請求の範囲第3項又は第4項に従属して第5項記載の注射器 。 7.更に、 前記カプセル室(19)の下流側端部に、該室内のカプセル(19A)の下流 側端部を穿通する手段(21A)を備えた、 ことを特徴とする前記請求の範囲のいずれか一項に記載の注射器。 8.前記カプセル(19A)が、弱化部(23)を備え、これにより、必要なガ ス圧が加わると、カプセルの下流側端部が容易に破れ、カプセルを通りノズル( 5)に沿った流れが形成されるようにした、 ことを特徴とする請求の範囲第2項に従属して第3項乃至第6項のいずれか一 項に記載の注射器。 9.前記カプセル室(19)とノズル(5)との間の相互連結が、更に、ノズル の軸線を横断して延びて破断可能な隔膜により、閉鎖されている、 ことを特徴とする請求の範囲第1項乃至第7項のいずれか一項に記載の注射器 。 10.前記請求の範囲の各項のいずれか一項に記載の注射器に使用され るカプセル(19A)であって、 ゼラチン状の壁を有すると共にドーム形の端部を有する略円筒状であって、粉 末薬剤の粒子を含む、 ことを特徴とするカプセル。 11.一方の端部に弱くて容易に破断可能な部分を形成した、 ことを特徴とする請求の範囲第10項記載のカプセル。
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB9421394A GB9421394D0 (en) | 1994-10-24 | 1994-10-24 | Particle delivery |
GB9421394.9 | 1994-10-24 | ||
PCT/GB1995/002498 WO1996012513A1 (en) | 1994-10-24 | 1995-10-20 | Particle delivery |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH10507390A true JPH10507390A (ja) | 1998-07-21 |
JP3853360B2 JP3853360B2 (ja) | 2006-12-06 |
Family
ID=26305858
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP51373196A Expired - Lifetime JP3853360B2 (ja) | 1994-10-24 | 1995-10-20 | 粒子供給装置 |
Country Status (6)
Country | Link |
---|---|
EP (1) | EP0788386B1 (ja) |
JP (1) | JP3853360B2 (ja) |
AU (1) | AU3703895A (ja) |
CA (1) | CA2199417C (ja) |
DE (1) | DE69507321T2 (ja) |
WO (1) | WO1996012513A1 (ja) |
Cited By (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003529392A (ja) * | 1999-04-16 | 2003-10-07 | パウダージェクト リサーチ リミテッド | 無針注射器 |
WO2013168800A1 (ja) * | 2012-05-11 | 2013-11-14 | 株式会社ダイセル | 注射器 |
JP2016179312A (ja) * | 2016-07-14 | 2016-10-13 | 株式会社ダイセル | 注射器 |
JP6286094B1 (ja) * | 2017-07-05 | 2018-02-28 | セルソース株式会社 | 細胞組織を含む流動体のための剪断装置 |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9426379D0 (en) | 1994-12-23 | 1995-03-01 | Oxford Biosciences Ltd | Particle delivery |
US7223739B1 (en) | 1995-06-07 | 2007-05-29 | Powderject Vaccines, Inc. | Adjuvanted genetic vaccines |
US6013050A (en) * | 1995-10-20 | 2000-01-11 | Powderject Research Limited | Particle delivery |
GB9605690D0 (en) * | 1996-03-19 | 1996-05-22 | Oxford Biosciences Ltd | Particle delivery |
AUPN976496A0 (en) | 1996-05-10 | 1996-05-30 | Glaxo Wellcome Australia Ltd | Unit dose dispensing device |
US6893664B1 (en) | 1996-06-17 | 2005-05-17 | Powderject Research Limited | Particle delivery techniques |
US5733600A (en) * | 1996-11-13 | 1998-03-31 | Powderject Vaccines, Inc. | Method and apparatus for preparing sample cartridges for a particle acceleration device |
US5947928A (en) * | 1997-06-19 | 1999-09-07 | Mile Creek Capital, Llc | Drug delivery system |
EP0888791A1 (en) * | 1997-07-04 | 1999-01-07 | PowderJect Research Limited | Syringe and drug capsule therefor |
EP0888790A1 (en) * | 1997-07-04 | 1999-01-07 | PowderJect Research Limited | Drug particle delivery device |
GB9802506D0 (en) * | 1998-02-05 | 1998-04-01 | Boc Group Plc | Needleless medical device |
US6602678B2 (en) | 1998-09-04 | 2003-08-05 | Powderject Research Limited | Non- or minimally invasive monitoring methods |
AU765763B2 (en) | 1998-09-04 | 2003-09-25 | Powderject Research Limited | Monitoring methods using particle delivery methods |
NZ510928A (en) | 1998-10-01 | 2002-10-25 | Powderject Res Ltd | Spray coated powder composition formed from seed particles between 10-100 micrometres coated with an aqueous pharmaceutical composition |
US6881723B1 (en) | 1998-11-05 | 2005-04-19 | Powderject Vaccines, Inc. | Nucleic acid constructs |
US6849060B1 (en) | 1999-01-29 | 2005-02-01 | Powderject Research Limited | Particle delivery device |
US6328714B1 (en) | 1999-01-29 | 2001-12-11 | Powderject Research Limited | Particle delivery device |
ATE298562T1 (de) | 1999-02-03 | 2005-07-15 | Powderject Res Ltd | Hydrogelpartikel formulierungen |
US7022320B1 (en) | 1999-02-09 | 2006-04-04 | Powderject Vaccines, Inc. | Mycobacterium tuberculosis immunization |
DE19910480C1 (de) | 1999-03-10 | 2000-09-28 | Skidata Ag | Nichtübertragbarer Berechtigungsausweis |
DE60017165T2 (de) | 1999-10-11 | 2006-01-12 | Felton International, Inc., Lenexa | Universelle antiinfektionsschutzvorrichtung für nadellose injektoren |
US7196066B1 (en) | 1999-11-03 | 2007-03-27 | Powderject Vaccines, Inc. | DNA-vaccines based on constructs derived from the genomes of human and animal pathogens |
US7887506B1 (en) | 1999-11-23 | 2011-02-15 | Pulse Needlefree Systems, Inc. | Safety mechanism to prevent accidental patient injection and methods of same |
US7029457B2 (en) | 1999-11-23 | 2006-04-18 | Felton International, Inc. | Jet injector with hand piece |
US6770054B1 (en) | 1999-11-23 | 2004-08-03 | Felton International, Inc. | Injector assembly with driving means and locking means |
FR2804329B1 (fr) | 2000-02-02 | 2002-12-13 | Poudres & Explosifs Ste Nale | Seringue sans aiguille munie d'un opercule contenant le principe actif |
GB0018035D0 (en) | 2000-07-21 | 2000-09-13 | Powderject Res Ltd | Needleless syringe |
DK1379273T3 (da) | 2000-11-27 | 2009-11-09 | Powderject Vaccines Inc | Nukleinsyreadjuvanser |
GB0100756D0 (en) | 2001-01-11 | 2001-02-21 | Powderject Res Ltd | Needleless syringe |
GB0118266D0 (en) | 2001-07-26 | 2001-09-19 | Powderject Res Ltd | Silencing device and method for needleless syringe |
WO2003052125A1 (en) | 2001-12-17 | 2003-06-26 | Powderject Research Limited | Non-or minimally invasive monitoring methods |
KR101152561B1 (ko) | 2002-09-27 | 2012-06-01 | 파우더젝트 리서치 리미티드 | 핵산 코팅된 입자 |
AU2005312301B2 (en) | 2004-12-01 | 2012-02-09 | Acushot Inc. | Needle-free injector |
GB0708758D0 (en) | 2007-05-04 | 2007-06-13 | Powderject Res Ltd | Particle cassettes and process thereof |
GB2479843B (en) | 2007-05-18 | 2012-02-29 | Malvern Instr Ltd | Method and apparatus for dispersing a sample of particulate material |
SI2701611T1 (sl) * | 2011-04-27 | 2015-11-30 | Biom'up | Razdeljevalnik biomedicinskega hemostatskega praška |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3949751A (en) * | 1970-03-03 | 1976-04-13 | Fisons Limited | Method and device for dispensing medicament to the body |
US3853125A (en) * | 1971-10-05 | 1974-12-10 | W Clark | Disposable needleless injector |
FR2224175B1 (ja) * | 1973-04-04 | 1978-04-14 | Isf Spa | |
US3998226A (en) * | 1975-09-22 | 1976-12-21 | Edward G. Gomez | Inhalation device for encapsulated concentrates |
SE466684B (sv) * | 1989-03-07 | 1992-03-23 | Draco Ab | Anordning vid en inhalator samt foerfarande foer att med anordningen registrera medicinering med inhalator |
DE69529495T2 (de) * | 1994-01-21 | 2003-06-12 | Powderject Vaccines Inc | Gasbetätigtes element zum austragen von genmaterial |
-
1995
- 1995-10-20 JP JP51373196A patent/JP3853360B2/ja not_active Expired - Lifetime
- 1995-10-20 DE DE69507321T patent/DE69507321T2/de not_active Expired - Lifetime
- 1995-10-20 EP EP95934724A patent/EP0788386B1/en not_active Expired - Lifetime
- 1995-10-20 CA CA002199417A patent/CA2199417C/en not_active Expired - Fee Related
- 1995-10-20 AU AU37038/95A patent/AU3703895A/en not_active Abandoned
- 1995-10-20 WO PCT/GB1995/002498 patent/WO1996012513A1/en active IP Right Grant
Cited By (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2003529392A (ja) * | 1999-04-16 | 2003-10-07 | パウダージェクト リサーチ リミテッド | 無針注射器 |
WO2013168800A1 (ja) * | 2012-05-11 | 2013-11-14 | 株式会社ダイセル | 注射器 |
JP2013236675A (ja) * | 2012-05-11 | 2013-11-28 | Daicel Corp | 注射器 |
CN104411352A (zh) * | 2012-05-11 | 2015-03-11 | 株式会社大赛璐 | 注射器 |
US9555193B2 (en) | 2012-05-11 | 2017-01-31 | Daicel Corporation | Syringe |
US9956346B2 (en) | 2012-05-11 | 2018-05-01 | Daicel Corporation | Syringe |
JP2016179312A (ja) * | 2016-07-14 | 2016-10-13 | 株式会社ダイセル | 注射器 |
JP6286094B1 (ja) * | 2017-07-05 | 2018-02-28 | セルソース株式会社 | 細胞組織を含む流動体のための剪断装置 |
JP2019013174A (ja) * | 2017-07-05 | 2019-01-31 | セルソース株式会社 | 細胞組織を含む流動体のための剪断装置 |
Also Published As
Publication number | Publication date |
---|---|
DE69507321T2 (de) | 1999-07-15 |
CA2199417C (en) | 2008-07-08 |
WO1996012513A1 (en) | 1996-05-02 |
DE69507321D1 (de) | 1999-02-25 |
EP0788386A1 (en) | 1997-08-13 |
EP0788386B1 (en) | 1999-01-13 |
CA2199417A1 (en) | 1996-05-02 |
JP3853360B2 (ja) | 2006-12-06 |
AU3703895A (en) | 1996-05-15 |
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