JPH10279468A - 皮膚外用剤 - Google Patents
皮膚外用剤Info
- Publication number
- JPH10279468A JPH10279468A JP9099668A JP9966897A JPH10279468A JP H10279468 A JPH10279468 A JP H10279468A JP 9099668 A JP9099668 A JP 9099668A JP 9966897 A JP9966897 A JP 9966897A JP H10279468 A JPH10279468 A JP H10279468A
- Authority
- JP
- Japan
- Prior art keywords
- extract
- lignan glycoside
- skin
- lignan
- glycoside
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 21
- -1 lignan glycoside Chemical class 0.000 claims abstract description 49
- 229930013686 lignan Natural products 0.000 claims abstract description 45
- 235000009408 lignans Nutrition 0.000 claims abstract description 45
- 229930182470 glycoside Natural products 0.000 claims abstract description 43
- 239000000284 extract Substances 0.000 claims abstract description 36
- FWKQNCXZGNBPFD-UHFFFAOYSA-N Guaiazulene Chemical compound CC(C)C1=CC=C(C)C2=CC=C(C)C2=C1 FWKQNCXZGNBPFD-UHFFFAOYSA-N 0.000 claims abstract description 10
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims abstract description 10
- CGIGDMFJXJATDK-UHFFFAOYSA-N indomethacin Chemical compound CC1=C(CC(O)=O)C2=CC(OC)=CC=C2N1C(=O)C1=CC=C(Cl)C=C1 CGIGDMFJXJATDK-UHFFFAOYSA-N 0.000 claims abstract description 10
- POJWUDADGALRAB-UHFFFAOYSA-N allantoin Chemical compound NC(=O)NC1NC(=O)NC1=O POJWUDADGALRAB-UHFFFAOYSA-N 0.000 claims abstract description 8
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims abstract description 7
- 229940121363 anti-inflammatory agent Drugs 0.000 claims abstract description 7
- 239000002260 anti-inflammatory agent Substances 0.000 claims abstract description 7
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- LPLVUJXQOOQHMX-QWBHMCJMSA-N glycyrrhizinic acid Chemical compound O([C@@H]1[C@@H](O)[C@H](O)[C@H](O[C@@H]1O[C@@H]1C([C@H]2[C@]([C@@H]3[C@@]([C@@]4(CC[C@@]5(C)CC[C@@](C)(C[C@H]5C4=CC3=O)C(O)=O)C)(C)CC2)(C)CC1)(C)C)C(O)=O)[C@@H]1O[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@H]1O LPLVUJXQOOQHMX-QWBHMCJMSA-N 0.000 claims abstract description 7
- VTAJIXDZFCRWBR-UHFFFAOYSA-N Licoricesaponin B2 Natural products C1C(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2)C(O)=O)C)(C)CC2)(C)C2C(C)(C)CC1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O VTAJIXDZFCRWBR-UHFFFAOYSA-N 0.000 claims abstract description 6
- LPLVUJXQOOQHMX-UHFFFAOYSA-N glycyrrhetinic acid glycoside Natural products C1CC(C2C(C3(CCC4(C)CCC(C)(CC4C3=CC2=O)C(O)=O)C)(C)CC2)(C)C2C(C)(C)C1OC1OC(C(O)=O)C(O)C(O)C1OC1OC(C(O)=O)C(O)C(O)C1O LPLVUJXQOOQHMX-UHFFFAOYSA-N 0.000 claims abstract description 6
- 239000001685 glycyrrhizic acid Substances 0.000 claims abstract description 6
- UYRUBYNTXSDKQT-UHFFFAOYSA-N glycyrrhizic acid Natural products CC1(C)C(CCC2(C)C1CCC3(C)C2C(=O)C=C4C5CC(C)(CCC5(C)CCC34C)C(=O)O)OC6OC(C(O)C(O)C6OC7OC(O)C(O)C(O)C7C(=O)O)C(=O)O UYRUBYNTXSDKQT-UHFFFAOYSA-N 0.000 claims abstract description 6
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- MPDGHEJMBKOTSU-YKLVYJNSSA-N 18beta-glycyrrhetic acid Chemical compound C([C@H]1C2=CC(=O)[C@H]34)[C@@](C)(C(O)=O)CC[C@]1(C)CC[C@@]2(C)[C@]4(C)CC[C@@H]1[C@]3(C)CC[C@H](O)C1(C)C MPDGHEJMBKOTSU-YKLVYJNSSA-N 0.000 claims description 4
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- SLXKOJJOQWFEFD-UHFFFAOYSA-N 6-aminohexanoic acid Chemical compound NCCCCCC(O)=O SLXKOJJOQWFEFD-UHFFFAOYSA-N 0.000 claims description 3
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- 239000003795 chemical substances by application Substances 0.000 claims description 3
- PJJGZPJJTHBVMX-UHFFFAOYSA-N 5,7-Dihydroxyisoflavone Chemical compound C=1C(O)=CC(O)=C(C2=O)C=1OC=C2C1=CC=CC=C1 PJJGZPJJTHBVMX-UHFFFAOYSA-N 0.000 claims description 2
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- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims description 2
- 239000011703 D-panthenol Substances 0.000 claims description 2
- 235000004866 D-panthenol Nutrition 0.000 claims description 2
- MPDGHEJMBKOTSU-UHFFFAOYSA-N Glycyrrhetinsaeure Natural products C12C(=O)C=C3C4CC(C)(C(O)=O)CCC4(C)CCC3(C)C1(C)CCC1C2(C)CCC(O)C1(C)C MPDGHEJMBKOTSU-UHFFFAOYSA-N 0.000 claims description 2
- HEFNNWSXXWATRW-UHFFFAOYSA-N Ibuprofen Chemical compound CC(C)CC1=CC=C(C(C)C(O)=O)C=C1 HEFNNWSXXWATRW-UHFFFAOYSA-N 0.000 claims description 2
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- QKSKPIVNLNLAAV-UHFFFAOYSA-N bis(2-chloroethyl) sulfide Chemical compound ClCCSCCCl QKSKPIVNLNLAAV-UHFFFAOYSA-N 0.000 claims description 2
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- 235000010460 mustard Nutrition 0.000 claims description 2
- 229960002895 phenylbutazone Drugs 0.000 claims description 2
- VYMDGNCVAMGZFE-UHFFFAOYSA-N phenylbutazonum Chemical compound O=C1C(CCCC)C(=O)N(C=2C=CC=CC=2)N1C1=CC=CC=C1 VYMDGNCVAMGZFE-UHFFFAOYSA-N 0.000 claims description 2
- JGMJQSFLQWGYMQ-UHFFFAOYSA-M sodium;2,6-dichloro-n-phenylaniline;acetate Chemical compound [Na+].CC([O-])=O.ClC1=CC=CC(Cl)=C1NC1=CC=CC=C1 JGMJQSFLQWGYMQ-UHFFFAOYSA-M 0.000 claims description 2
- 235000020712 soy bean extract Nutrition 0.000 claims description 2
- 241000086254 Arnica montana Species 0.000 claims 1
- 235000015701 Artemisia arbuscula Nutrition 0.000 claims 1
- 235000002657 Artemisia tridentata Nutrition 0.000 claims 1
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- 240000006891 Artemisia vulgaris Species 0.000 claims 1
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- 235000017945 Matricaria Nutrition 0.000 abstract 1
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- 238000000034 method Methods 0.000 description 16
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- 239000000401 methanolic extract Substances 0.000 description 9
- PUPZLCDOIYMWBV-UHFFFAOYSA-N (+/-)-1,3-Butanediol Chemical compound CC(O)CCO PUPZLCDOIYMWBV-UHFFFAOYSA-N 0.000 description 8
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- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 description 6
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- PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 description 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- JXTPJDDICSTXJX-UHFFFAOYSA-N n-Triacontane Natural products CCCCCCCCCCCCCCCCCCCCCCCCCCCCCC JXTPJDDICSTXJX-UHFFFAOYSA-N 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 238000004810 partition chromatography Methods 0.000 description 1
- 239000002304 perfume Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 229940127557 pharmaceutical product Drugs 0.000 description 1
- 239000001818 polyoxyethylene sorbitan monostearate Substances 0.000 description 1
- 235000010989 polyoxyethylene sorbitan monostearate Nutrition 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- 238000004445 quantitative analysis Methods 0.000 description 1
- 229920006395 saturated elastomer Polymers 0.000 description 1
- 235000020637 scallop Nutrition 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 229940032094 squalane Drugs 0.000 description 1
- 229910001220 stainless steel Inorganic materials 0.000 description 1
- 239000010935 stainless steel Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 238000006227 trimethylsilylation reaction Methods 0.000 description 1
- 238000005406 washing Methods 0.000 description 1
Landscapes
- Cosmetics (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9099668A JPH10279468A (ja) | 1997-04-01 | 1997-04-01 | 皮膚外用剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP9099668A JPH10279468A (ja) | 1997-04-01 | 1997-04-01 | 皮膚外用剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH10279468A true JPH10279468A (ja) | 1998-10-20 |
| JPH10279468A5 JPH10279468A5 (OSRAM) | 2005-03-03 |
Family
ID=14253421
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP9099668A Pending JPH10279468A (ja) | 1997-04-01 | 1997-04-01 | 皮膚外用剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPH10279468A (OSRAM) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000136122A (ja) * | 1998-10-28 | 2000-05-16 | Kose Corp | 皮膚外用剤 |
| US8075926B2 (en) | 2001-05-23 | 2011-12-13 | Izun Pharmaceuticals Corporation | Herbal compositions for the treatment of mucosal lesions |
| JP2013001684A (ja) * | 2011-06-17 | 2013-01-07 | Ssp Co Ltd | 表皮ターンオーバー促進剤 |
| JP2013155141A (ja) * | 2012-01-31 | 2013-08-15 | Mikimoto Pharmaceut Co Ltd | 化粧料 |
| CN113164604A (zh) * | 2018-11-02 | 2021-07-23 | 株式会社资生堂 | 包含替代性自噬诱导剂的紫外线引发性炎症抑制剂 |
| CN115212157A (zh) * | 2022-07-14 | 2022-10-21 | 广东瀚润生物科技有限公司 | 美白祛斑抗衰老的天然植萃复配草本原料制备方法及其应用 |
-
1997
- 1997-04-01 JP JP9099668A patent/JPH10279468A/ja active Pending
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2000136122A (ja) * | 1998-10-28 | 2000-05-16 | Kose Corp | 皮膚外用剤 |
| US8075926B2 (en) | 2001-05-23 | 2011-12-13 | Izun Pharmaceuticals Corporation | Herbal compositions for the treatment of mucosal lesions |
| US9855307B2 (en) | 2001-05-23 | 2018-01-02 | Izun Pharmaceuticals Corporation | Herbal compositions for the treatment of mucosal lesions |
| JP2013001684A (ja) * | 2011-06-17 | 2013-01-07 | Ssp Co Ltd | 表皮ターンオーバー促進剤 |
| JP2013155141A (ja) * | 2012-01-31 | 2013-08-15 | Mikimoto Pharmaceut Co Ltd | 化粧料 |
| CN113164604A (zh) * | 2018-11-02 | 2021-07-23 | 株式会社资生堂 | 包含替代性自噬诱导剂的紫外线引发性炎症抑制剂 |
| CN115212157A (zh) * | 2022-07-14 | 2022-10-21 | 广东瀚润生物科技有限公司 | 美白祛斑抗衰老的天然植萃复配草本原料制备方法及其应用 |
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