JPH08508283A - ペルヒドロイソインドール誘導体、それらの製造およびそれらを含有する薬学的組成物 - Google Patents

ペルヒドロイソインドール誘導体、それらの製造およびそれらを含有する薬学的組成物

Info

Publication number
JPH08508283A
JPH08508283A JP6521762A JP52176294A JPH08508283A JP H08508283 A JPH08508283 A JP H08508283A JP 6521762 A JP6521762 A JP 6521762A JP 52176294 A JP52176294 A JP 52176294A JP H08508283 A JPH08508283 A JP H08508283A
Authority
JP
Japan
Prior art keywords
group
methoxyphenyl
diphenyl
perhydro
optionally
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6521762A
Other languages
English (en)
Japanese (ja)
Inventor
クレスポ,アンドレ
フアルダン,ベロニク
ギローム,ジヤン−マルク
マレロン,ジヤン−リユク
ペロネル,ジヤン−フランソワ
Original Assignee
ローン−プーラン・ロレ・ソシエテ・アノニム
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ローン−プーラン・ロレ・ソシエテ・アノニム filed Critical ローン−プーラン・ロレ・ソシエテ・アノニム
Publication of JPH08508283A publication Critical patent/JPH08508283A/ja
Pending legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D403/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00Drugs for disorders of the respiratory system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Cardiology (AREA)
  • Rheumatology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Neurosurgery (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
JP6521762A 1993-04-05 1994-04-01 ペルヒドロイソインドール誘導体、それらの製造およびそれらを含有する薬学的組成物 Pending JPH08508283A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR93/03965 1993-04-05
FR9303965A FR2703679B1 (fr) 1993-04-05 1993-04-05 Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
PCT/FR1994/000371 WO1994022822A1 (fr) 1993-04-05 1994-04-01 Derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
JPH08508283A true JPH08508283A (ja) 1996-09-03

Family

ID=9445733

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6521762A Pending JPH08508283A (ja) 1993-04-05 1994-04-01 ペルヒドロイソインドール誘導体、それらの製造およびそれらを含有する薬学的組成物

Country Status (21)

Country Link
US (1) US5631279A (fi)
EP (1) EP0693059B1 (fi)
JP (1) JPH08508283A (fi)
KR (1) KR960701842A (fi)
AT (1) ATE150014T1 (fi)
AU (1) AU6506894A (fi)
CA (1) CA2158663A1 (fi)
CZ (1) CZ258495A3 (fi)
DE (1) DE69402058T2 (fi)
DK (1) DK0693059T3 (fi)
ES (1) ES2099601T3 (fi)
FI (1) FI954730A (fi)
FR (1) FR2703679B1 (fi)
GR (1) GR3022798T3 (fi)
HU (1) HUT74089A (fi)
IL (1) IL109217A0 (fi)
NO (1) NO953913D0 (fi)
PL (1) PL310948A1 (fi)
SK (1) SK123595A3 (fi)
TW (1) TW333525B (fi)
WO (1) WO1994022822A1 (fi)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW432061B (en) * 1994-08-09 2001-05-01 Pfizer Res & Dev Lactams
FR2737495B1 (fr) * 1995-08-02 1997-08-29 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent
GB9816897D0 (en) * 1998-08-04 1998-09-30 Merck Sharp & Dohme Therapeutic use
DE102006007882A1 (de) 2006-02-21 2007-08-30 Bayer Cropscience Ag Cycloalkyl-phenylsubstituierte cyclische Ketoenole
WO2013128465A1 (en) * 2011-12-22 2013-09-06 Connexios Life Sciences Pvt. Ltd. Cyclic amide derivatives as inhibitors of 11 - beta - hydroxysteroid dehydrogenase and uses thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6372689A (ja) * 1986-09-16 1988-04-02 Taisho Pharmaceut Co Ltd (−)−α−カイニン酸の中間体およびその製造方法
FR2654726B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone et leur preparation.
FR2654725B1 (fr) * 1989-11-23 1992-02-14 Rhone Poulenc Sante Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2676443B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole et leur preparation.
FR2676442B1 (fr) * 1991-05-17 1993-08-06 Rhone Poulenc Rorer Sa Nouveau derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.
FR2689889B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, et leur preparation.
FR2689888B1 (fr) * 1992-04-10 1994-06-10 Rhone Poulenc Rorer Sa Nouveaux derives de perhydroisoindole, leur preparation et les compositions pharmaceutiques qui les contiennent.

Also Published As

Publication number Publication date
US5631279A (en) 1997-05-20
ATE150014T1 (de) 1997-03-15
AU6506894A (en) 1994-10-24
KR960701842A (ko) 1996-03-28
GR3022798T3 (en) 1997-06-30
EP0693059B1 (fr) 1997-03-12
CA2158663A1 (fr) 1994-10-13
HUT74089A (en) 1996-11-28
NO953913L (no) 1995-10-02
CZ258495A3 (en) 1996-01-17
WO1994022822A1 (fr) 1994-10-13
FR2703679B1 (fr) 1995-06-23
HU9502902D0 (en) 1995-11-28
DK0693059T3 (da) 1997-09-15
FI954730A (fi) 1995-11-17
NO953913D0 (no) 1995-10-02
EP0693059A1 (fr) 1996-01-24
SK123595A3 (en) 1996-06-05
DE69402058D1 (de) 1997-04-17
IL109217A0 (en) 1994-07-31
FR2703679A1 (fr) 1994-10-14
ES2099601T3 (es) 1997-05-16
DE69402058T2 (de) 1997-09-18
PL310948A1 (en) 1996-01-08
FI954730A0 (fi) 1995-10-04
TW333525B (en) 1998-06-11

Similar Documents

Publication Publication Date Title
US5484804A (en) Perhydroisoindole derivatives as antagonists of substance P
US5739351A (en) Perhydroisoindole derivatives as substance P antagonists
US5624950A (en) Perhydroisoindole derivatives as substance P antagonists
CN1141043A (zh) 非肽类速激肽受体拮抗剂
JPH0649027A (ja) インドール誘導体
JP2000502100A (ja) タキキニン拮抗薬としてのピペラジン誘導体
TW438773B (en) Indole derivatives
JPH08507300A (ja) 興奮性アミノ酸の拮抗剤としてのインドール誘導体
JPH05506643A (ja) N―フエニル―n―アセトアミドグリシンアミド類、それらの製造およびそれらを含有する薬物
AU635099B2 (en) Quinazoline derivatives and their preparation
JPH08508283A (ja) ペルヒドロイソインドール誘導体、それらの製造およびそれらを含有する薬学的組成物
CZ248394A3 (en) Novel derivatives of perhydroisoindole and process of their preparation
JPS6115875A (ja) コレシストキニン拮抗剤として有用なベンゼン環と縮環したラクタム化合物
WO1997005110A1 (en) Perhydroisoindole derivatives as substance p and neurokinine a antagonists
JPH0641126A (ja) β−カルボリン誘導体
JPH07145055A (ja) コレシストキニン拮抗薬
FR2709752A1 (fr) Nouveaux dérivés de perhydroisoindole, leur préparation et les compositions pharmaceutiques qui les contiennent.