JPH08502492A - 治療用ミクロエマルジョン - Google Patents

治療用ミクロエマルジョン

Info

Publication number
JPH08502492A
JPH08502492A JP6510336A JP51033694A JPH08502492A JP H08502492 A JPH08502492 A JP H08502492A JP 6510336 A JP6510336 A JP 6510336A JP 51033694 A JP51033694 A JP 51033694A JP H08502492 A JPH08502492 A JP H08502492A
Authority
JP
Japan
Prior art keywords
aliphatic acyl
composition
medium
phase
oil
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP6510336A
Other languages
English (en)
Japanese (ja)
Inventor
コンスタンティニデス，パナイオティス・ペリクリウス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JPH08502492A publication Critical patent/JPH08502492A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF] (Somatoliberin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
JP6510336A 1992-10-16 1993-10-15 治療用ミクロエマルジョン Pending JPH08502492A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96295792A 1992-10-16 1992-10-16
US07/962,957 1992-10-16
PCT/US1993/009963 WO1994008605A1 (fr) 1992-10-16 1993-10-15 Microemulsions therapeutiques

Publications (1)

Publication Number Publication Date
JPH08502492A true JPH08502492A (ja) 1996-03-19

Family

ID=25506555

Family Applications (1)

Application Number Title Priority Date Filing Date
JP6510336A Pending JPH08502492A (ja) 1992-10-16 1993-10-15 治療用ミクロエマルジョン

Country Status (3)

Country Link
EP (1) EP0666752A4 (fr)
JP (1) JPH08502492A (fr)
WO (1) WO1994008605A1 (fr)

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011504871A (ja) * 2007-06-01 2011-02-17 ノボ・ノルデイスク・エー／エス 固体又は半固体担体中にペプチド薬剤を含む自然に分散可能なプレコンセントレイト
JP2011213733A (ja) * 2000-05-18 2011-10-27 Aeterna Zentaris Gmbh ペプチドの薬剤適用形、その製造法及び使用
US9481721B2 (en) 2012-04-11 2016-11-01 Novo Nordisk A/S Insulin formulations
US9688737B2 (en) 2008-03-18 2017-06-27 Novo Nordisk A/S Protease stabilized acylated insulin analogues
US10265385B2 (en) 2016-12-16 2019-04-23 Novo Nordisk A/S Insulin containing pharmaceutical compositions

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0580778B1 (fr) * 1991-04-19 1999-08-11 LDS Technologies, Inc. Formulations de microemulsions a inversion de phase
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
US5948825A (en) * 1993-04-19 1999-09-07 Institute For Advanced Skin Research Inc. Microemulsion preparation containing a slightly absorbable substance
ATE406909T1 (de) * 1993-05-13 2008-09-15 Poniard Pharmaceuticals Inc Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind
EP0788346B9 (fr) * 1994-03-18 2007-02-14 Supernus Pharmaceuticals, Inc. Systemes d'administration de medicaments emulsionnes
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
AU698317B2 (en) 1995-02-25 1998-10-29 Cancer Research Technology Limited Transgenic animals as model of psoriasis
US5824638A (en) * 1995-05-22 1998-10-20 Shire Laboratories, Inc. Oral insulin delivery
US6008228A (en) * 1995-06-06 1999-12-28 Hoffman-La Roche Inc. Pharmaceutical compositions containing proteinase inhibitors
US5734770A (en) * 1995-06-29 1998-03-31 Minnesota Mining And Manufacturing Company Cleave and bevel fiber optic connector
US5660858A (en) * 1996-04-03 1997-08-26 Research Triangle Pharmaceuticals Cyclosporin emulsions
GB9613858D0 (en) * 1996-07-02 1996-09-04 Cortecs Ltd Hydrophobic preparations
AU5142398A (en) * 1996-11-22 1998-06-10 Pharmacia & Upjohn Ab Pharmaceutical composition based on a lipid matrix system
ES2226120T3 (es) 1997-03-31 2005-03-16 Boston Scientific Limited Inhibidor terapeutico de celulas del musculo liso vascular.
EP1039893B1 (fr) 1997-12-10 2011-02-02 Cyclosporine Therapeutics Limited Compositions pharmaceutiques contenant une huile d'acide gras omega-3
WO1999053941A1 (fr) * 1998-04-15 1999-10-28 Shionogi & Co., Ltd. Preparations orales contenant des derives de trh
US20020155084A1 (en) * 2000-06-02 2002-10-24 The Regents Of The University Of The Michigan Nanoemulsion formulations
CN1160122C (zh) 2001-04-20 2004-08-04 清华大学 一种制备口服胰岛素油相制剂的方法
JP4251988B2 (ja) 2001-12-14 2009-04-08 ヤーゴテック アクチェンゲゼルシャフト シクロスポリンを含む医薬製剤およびその使用
PE20050596A1 (es) * 2003-12-19 2005-10-18 Novartis Ag Microemulsion que comprende un inhibidor renina
CA2560613C (fr) 2004-03-22 2015-11-24 Solvay Pharmaceuticals Gmbh Compositions pharmaceutiques par voie orale a base de lipases, en particulier de pancreatine, contenant des tensioacitfs
US9743680B2 (en) * 2005-10-14 2017-08-29 Wild Flavors, Inc. Microemulsions for use in food and beverage products
EP1961412A1 (fr) * 2006-12-27 2008-08-27 LEK Pharmaceuticals D.D. Systèmes auto-microémulsifiants pour l'administration de médicaments
GB201107630D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Microemulsions
KR101991661B1 (ko) * 2017-03-02 2019-06-21 대화제약 주식회사 자나미비르를 포함하는 안정한 약제학적 조성물
WO2018159941A1 (fr) * 2017-03-02 2018-09-07 대화제약 주식회사 Composition pharmaceutique stable comprenant du zanamivir

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
IE60024B1 (en) * 1987-02-03 1994-05-18 Stiefel Laboratories Ltd Microemulsions
DE3908047A1 (de) * 1989-03-13 1990-09-20 Desitin Arzneimittel Gmbh Hochdisperse pharmazeutische zusammensetzung
JPH06511419A (ja) * 1990-06-08 1994-12-22 アフィニティー　バイオテック，インコーポレイテッド ミクロエマルジョンを製造する方法
US5110606A (en) * 1990-11-13 1992-05-05 Affinity Biotech, Inc. Non-aqueous microemulsions for drug delivery
EP0580778B1 (fr) * 1991-04-19 1999-08-11 LDS Technologies, Inc. Formulations de microemulsions a inversion de phase
JPH06509577A (ja) * 1991-07-26 1994-10-27 スミスクライン・ビーチャム・コーポレイション Ｗ／ｏミクロエマルジョン
IL102633A0 (en) * 1991-07-26 1993-01-14 Smithkline Beecham Corp Compositions

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2011213733A (ja) * 2000-05-18 2011-10-27 Aeterna Zentaris Gmbh ペプチドの薬剤適用形、その製造法及び使用
JP2011504871A (ja) * 2007-06-01 2011-02-17 ノボ・ノルデイスク・エー／エス 固体又は半固体担体中にペプチド薬剤を含む自然に分散可能なプレコンセントレイト
US9688737B2 (en) 2008-03-18 2017-06-27 Novo Nordisk A/S Protease stabilized acylated insulin analogues
US10259856B2 (en) 2008-03-18 2019-04-16 Novo Nordisk A/S Protease stabilized acylated insulin analogues
US9481721B2 (en) 2012-04-11 2016-11-01 Novo Nordisk A/S Insulin formulations
US10265385B2 (en) 2016-12-16 2019-04-23 Novo Nordisk A/S Insulin containing pharmaceutical compositions
US10596231B2 (en) 2016-12-16 2020-03-24 Novo Nordisk A/S Insulin containing pharmaceutical compositions

Also Published As

Publication number Publication date
WO1994008605A1 (fr) 1994-04-28
EP0666752A4 (fr) 1996-09-11
EP0666752A1 (fr) 1995-08-16

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