ES2093269T3 - Microemulsiones del tipo agua en aceite. - Google Patents

Microemulsiones del tipo agua en aceite.

Info

Publication number
ES2093269T3
ES2093269T3 ES92916973T ES92916973T ES2093269T3 ES 2093269 T3 ES2093269 T3 ES 2093269T3 ES 92916973 T ES92916973 T ES 92916973T ES 92916973 T ES92916973 T ES 92916973T ES 2093269 T3 ES2093269 T3 ES 2093269T3
Authority
ES
Spain
Prior art keywords
microemulsions
water
oil type
hlb surfactant
emulsifying
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES92916973T
Other languages
English (en)
Inventor
Panayiotis Peri Constantinides
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=24959558&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES2093269(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Application granted granted Critical
Publication of ES2093269T3 publication Critical patent/ES2093269T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Dispersion Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biophysics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

SE PRESENTAN MICROEMULSIONES AUTOEMULSIFICANTES, ESTABLES Y FARMACEUTICAMENTE ACEPTABLES (W/O) QUE COMPRENDEN I) UNA FASE LIPOFILICA QUE COMPRENDE UN TRIGLICERIDO DE UN ACIDO GRASO DE CADENA MEDIA Y UN SURFACTANTE DE HLB INFERIOR, II) UNA FASE HIDROFILICA DE BASE ACUOSA QUE CONTIENE UN AGENTE TERAPEUTICO SOLUBLE EN AGUA, Y III) UN SURFACTANTE DE ALTO HLB QUE TIENEN UNAS CARACTERISTICAS MEJORADAS PARA EL SUMINISTRO DE DROGAS.
ES92916973T 1991-07-26 1992-07-24 Microemulsiones del tipo agua en aceite. Expired - Lifetime ES2093269T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US73635491A 1991-07-26 1991-07-26

Publications (1)

Publication Number Publication Date
ES2093269T3 true ES2093269T3 (es) 1996-12-16

Family

ID=24959558

Family Applications (1)

Application Number Title Priority Date Filing Date
ES92916973T Expired - Lifetime ES2093269T3 (es) 1991-07-26 1992-07-24 Microemulsiones del tipo agua en aceite.

Country Status (15)

Country Link
EP (1) EP0597007B1 (es)
JP (1) JPH06509796A (es)
AT (1) ATE144137T1 (es)
AU (1) AU667316B2 (es)
CA (1) CA2114141A1 (es)
DE (1) DE69214652T2 (es)
DK (1) DK0597007T3 (es)
ES (1) ES2093269T3 (es)
GR (1) GR3022260T3 (es)
IL (1) IL102633A0 (es)
MX (1) MX9204379A (es)
NZ (1) NZ243703A (es)
PT (1) PT100726A (es)
WO (1) WO1993002664A1 (es)
ZA (1) ZA925581B (es)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
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WO1992018147A1 (en) * 1991-04-19 1992-10-29 Affinity Biotech, Inc. Convertible microemulsion formulations
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
JPH06509577A (ja) * 1991-07-26 1994-10-27 スミスクライン・ビーチャム・コーポレイション Ｗ／ｏミクロエマルジョン
EP0671929A4 (en) * 1992-10-16 1996-09-25 Smithkline Beecham Corp COMPOSITIONS.
WO1994008605A1 (en) * 1992-10-16 1994-04-28 Smithkline Beecham Corporation Therapeutic microemulsions
EP0746331B1 (en) * 1992-10-16 2000-09-13 IBAH, Inc. Convertible microemulsion formulations
JPH08507078A (ja) * 1993-02-17 1996-07-30 スミスクライン・ビーチャム・コーポレイション 治療用ペプチド含有のミクロエマルジョン
ES2182841T3 (es) * 1993-04-19 2003-03-16 Inst Advanced Skin Res Inc Preparacion en microemulsion conteniendo una substancia dificilmente absorbible.
WO1995009058A2 (en) * 1993-09-29 1995-04-06 Technobiochip Protein thin films and compositions for use in their preparation
AU692506B2 (en) * 1993-11-17 1998-06-11 Ibah, Inc. Transparent liquid for encapsulated drug delivery
CA2185803C (en) * 1994-03-18 2006-07-11 Edward M. Rudnic Emulsified drug delivery systems
US5824638A (en) * 1995-05-22 1998-10-20 Shire Laboratories, Inc. Oral insulin delivery
SE9503143D0 (sv) 1995-09-12 1995-09-12 Astra Ab New preparation
GB9613858D0 (en) * 1996-07-02 1996-09-04 Cortecs Ltd Hydrophobic preparations
TWI241915B (en) 1998-05-11 2005-10-21 Ciba Sc Holding Ag A method of preparing a pharmaceutical end formulation using a nanodispersion
US6242001B1 (en) * 1998-11-30 2001-06-05 Mcneil-Ppc, Inc. Method for producing dispersible sterol and stanol compounds
WO2000033866A1 (en) * 1998-12-04 2000-06-15 Provalis Uk Limited Pharmaceutical compositions containing insulin
US6828297B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of insulin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6713452B2 (en) 2001-06-04 2004-03-30 Nobex Corporation Mixtures of calcitonin drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6828305B2 (en) 2001-06-04 2004-12-07 Nobex Corporation Mixtures of growth hormone drug-oligomer conjugates comprising polyalkylene glycol, uses thereof, and methods of making same
US6835802B2 (en) 2001-06-04 2004-12-28 Nobex Corporation Methods of synthesizing substantially monodispersed mixtures of polymers having polyethylene glycol moieties
US7713932B2 (en) 2001-06-04 2010-05-11 Biocon Limited Calcitonin drug-oligomer conjugates, and uses thereof
ATE424815T1 (de) 2001-12-03 2009-03-15 Dor Biopharma Inc Stabilisierte umkehr-mizellen-zusammensetzungen und ihre verwendung
JP4251988B2 (ja) 2001-12-14 2009-04-08 ヤーゴテック アクチェンゲゼルシャフト シクロスポリンを含む医薬製剤およびその使用
US20050232974A1 (en) * 2004-04-19 2005-10-20 Gore Makarand P System and a method for pharmaceutical dosage preparation using jettable microemulsions
CA2580313C (en) 2004-07-19 2016-03-15 Biocon Limited Insulin-oligomer conjugates, formulations and uses thereof
DK2985026T3 (da) 2005-04-15 2022-10-31 Clarus Therapeutics Inc Farmaceutiske leveringssystemer til hydrofobe lægemidler og sammensætninger dermed
US8492369B2 (en) 2010-04-12 2013-07-23 Clarus Therapeutics Inc Oral testosterone ester formulations and methods of treating testosterone deficiency comprising same
ITMI20060618A1 (it) * 2006-03-31 2007-10-01 Enitecnologie Spa Procedimento per la preparazione di nanoemulsioni acqua ion olio e olio in acqua
EP1961412A1 (en) * 2006-12-27 2008-08-27 LEK Pharmaceuticals D.D. Self-microemulsifying drug delivery systems
WO2008145728A1 (en) * 2007-06-01 2008-12-04 Novo Nordisk A/S Spontaneously dispersible preconcentrates including a peptide drug in a solid or semisolid carrier
CN101772352B (zh) * 2007-09-27 2012-05-23 理研维他命株式会社 软胶囊填充用液态组合物
JP5156458B2 (ja) * 2008-03-31 2013-03-06 理研ビタミン株式会社 ソフトカプセル充填用液状組成物
JP5868594B2 (ja) 2007-10-16 2016-02-24 バイオコン・リミテッドＢｉｏｃｏｎ Ｌｉｍｉｔｅｄ 経口投与可能な固形医薬組成物及びそのプロセス
MX2010009850A (es) 2008-03-18 2010-09-30 Novo Nordisk As Analogos de insulina acilados y etabilizados contra proteasas.
US11304960B2 (en) 2009-01-08 2022-04-19 Chandrashekar Giliyar Steroidal compositions
WO2011004395A1 (en) * 2009-07-06 2011-01-13 Intas Biopharmaceuticals Limited Microemulsion formulation for biologicals
RU2560677C2 (ru) * 2009-12-22 2015-08-20 Лео Фарма А/С Кожная композиция, включающая аналог витамина d и смесь растворителя и поверхностно-активных веществ
CA2690490C (en) * 2010-01-19 2012-06-26 Accucaps Industries Limited Pharmaceutical formulations of loratadine for encapsulation and combinations thereof
US20120058187A1 (en) * 2010-09-03 2012-03-08 Novagali Pharma Sa Water-in-oil type emulsion for treating a disease of the eye
US9358241B2 (en) 2010-11-30 2016-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US20180153904A1 (en) 2010-11-30 2018-06-07 Lipocine Inc. High-strength testosterone undecanoate compositions
US9034858B2 (en) 2010-11-30 2015-05-19 Lipocine Inc. High-strength testosterone undecanoate compositions
US20120148675A1 (en) 2010-12-10 2012-06-14 Basawaraj Chickmath Testosterone undecanoate compositions
GB201107629D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Hydrophobic preparations
GB201107630D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Microemulsions
MX2014012096A (es) 2012-04-11 2014-11-21 Novo Nordisk As Formulaciones de insulina.
WO2016033556A1 (en) 2014-08-28 2016-03-03 Lipocine Inc. BIOAVAILABLE SOLID STATE (17-β)-HYDROXY-4-ANDROSTEN-3-ONE ESTERS
WO2016033549A2 (en) 2014-08-28 2016-03-03 Lipocine Inc. (17-ß)-3-OXOANDROST-4-EN-17-YL TRIDECANOATE COMPOSITIONS AND METHODS OF THEIR PREPARATION AND USE
US20180147215A1 (en) 2016-11-28 2018-05-31 Lipocine Inc. Oral testosterone undecanoate therapy
AU2017378102B2 (en) 2016-12-16 2022-10-13 Novo Nordisk A/S Insulin containing pharmaceutical compositions

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1080994A (en) * 1963-10-25 1967-08-31 Nat Res Dev Injectable emulsions containing antigens
US4840660A (en) * 1985-12-30 1989-06-20 Rhone Poulenc Nederlands B.V. Plant growth regulator dispersions
IE60024B1 (en) * 1987-02-03 1994-05-18 Stiefel Laboratories Ltd Microemulsions
JPH06509577A (ja) * 1991-07-26 1994-10-27 スミスクライン・ビーチャム・コーポレイション Ｗ／ｏミクロエマルジョン

Also Published As

Publication number Publication date
EP0597007A1 (en) 1994-05-18
WO1993002664A1 (en) 1993-02-18
NZ243703A (en) 1995-12-21
IL102633A0 (en) 1993-01-14
CA2114141A1 (en) 1993-02-18
DE69214652T2 (de) 1997-03-20
MX9204379A (es) 1993-02-01
JPH06509796A (ja) 1994-11-02
ZA925581B (en) 1993-05-14
ATE144137T1 (de) 1996-11-15
DE69214652D1 (de) 1996-11-21
AU2411592A (en) 1993-03-02
AU667316B2 (en) 1996-03-21
EP0597007B1 (en) 1996-10-16
DK0597007T3 (da) 1996-11-18
GR3022260T3 (en) 1997-04-30
PT100726A (pt) 1993-09-30

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