EP0666752A4 - Microemulsions therapeutiques. - Google Patents

Microemulsions therapeutiques.

Info

Publication number
EP0666752A4
EP0666752A4 EP93923933A EP93923933A EP0666752A4 EP 0666752 A4 EP0666752 A4 EP 0666752A4 EP 93923933 A EP93923933 A EP 93923933A EP 93923933 A EP93923933 A EP 93923933A EP 0666752 A4 EP0666752 A4 EP 0666752A4
Authority
EP
European Patent Office
Prior art keywords
microemulsions
therapeutic
therapeutic microemulsions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
EP93923933A
Other languages
German (de)
English (en)
Other versions
EP0666752A1 (fr
Inventor
Panayiotis Peri Constantinides
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of EP0666752A1 publication Critical patent/EP0666752A1/fr
Publication of EP0666752A4 publication Critical patent/EP0666752A4/fr
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/10—Dispersions; Emulsions
    • A61K9/107—Emulsions ; Emulsion preconcentrates; Micelles
    • A61K9/1075—Microemulsions or submicron emulsions; Preconcentrates or solids thereof; Micelles, e.g. made of phospholipids or block copolymers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/04—Peptides having up to 20 amino acids in a fully defined sequence; Derivatives thereof
    • A61K38/08—Peptides having 5 to 11 amino acids
    • A61K38/095—Oxytocins; Vasopressins; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/22—Hormones
    • A61K38/25—Growth hormone-releasing factor [GH-RF] (Somatoliberin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/39—Connective tissue peptides, e.g. collagen, elastin, laminin, fibronectin, vitronectin, cold insoluble globulin [CIG]
EP93923933A 1992-10-16 1993-10-15 Microemulsions therapeutiques. Withdrawn EP0666752A4 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US96295792A 1992-10-16 1992-10-16
US962957 1992-10-16
PCT/US1993/009963 WO1994008605A1 (fr) 1992-10-16 1993-10-15 Microemulsions therapeutiques

Publications (2)

Publication Number Publication Date
EP0666752A1 EP0666752A1 (fr) 1995-08-16
EP0666752A4 true EP0666752A4 (fr) 1996-09-11

Family

ID=25506555

Family Applications (1)

Application Number Title Priority Date Filing Date
EP93923933A Withdrawn EP0666752A4 (fr) 1992-10-16 1993-10-15 Microemulsions therapeutiques.

Country Status (3)

Country Link
EP (1) EP0666752A4 (fr)
JP (1) JPH08502492A (fr)
WO (1) WO1994008605A1 (fr)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0580778B1 (fr) * 1991-04-19 1999-08-11 LDS Technologies, Inc. Formulations de microemulsions a inversion de phase
US5688761A (en) * 1991-04-19 1997-11-18 Lds Technologies, Inc. Convertible microemulsion formulations
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
ATE223231T1 (de) * 1993-04-19 2002-09-15 Inst Advanced Skin Res Inc Mikroemulsionszubereitung enthaltend eine schwer absorbierbare substanz
ATE406909T1 (de) * 1993-05-13 2008-09-15 Poniard Pharmaceuticals Inc Prävention und behandlung von pathologien, die mit einer abnormalen proliferationglatter muskelzellen verbunden sind
US5952004A (en) * 1994-03-18 1999-09-14 Shire Laboratories Inc. Emulsified drug delivery systems
HU215966B (hu) * 1994-11-21 1999-07-28 BIOGAL Gyógyszergyár Rt. Orálisan alkalmazható, ciklosporint tartalmazó, összetett emulzió-előkoncentrátum
AU698317B2 (en) 1995-02-25 1998-10-29 Cancer Research Technology Limited Transgenic animals as model of psoriasis
US5824638A (en) * 1995-05-22 1998-10-20 Shire Laboratories, Inc. Oral insulin delivery
US6008228A (en) * 1995-06-06 1999-12-28 Hoffman-La Roche Inc. Pharmaceutical compositions containing proteinase inhibitors
US5734770A (en) * 1995-06-29 1998-03-31 Minnesota Mining And Manufacturing Company Cleave and bevel fiber optic connector
US5660858A (en) * 1996-04-03 1997-08-26 Research Triangle Pharmaceuticals Cyclosporin emulsions
GB9613858D0 (en) 1996-07-02 1996-09-04 Cortecs Ltd Hydrophobic preparations
WO1998022089A1 (fr) * 1996-11-22 1998-05-28 Pharmacia & Upjohn Ab Composition pharmaceutique a base de systeme matriciel lipidique
ES2388248T3 (es) 1997-03-31 2012-10-11 Boston Scientific Scimed Limited Forma de dosificación que comprende taxol en forma cristalina
KR100587551B1 (ko) 1997-12-10 2006-06-08 싸이클로스포린 테라퓨틱스 리미티드 오메가-3 지방산 오일을 함유하는 약학 조성물
WO1999053941A1 (fr) * 1998-04-15 1999-10-28 Shionogi & Co., Ltd. Preparations orales contenant des derives de trh
DE10024451A1 (de) * 2000-05-18 2001-11-29 Asta Medica Ag Pharmazeutische Darreichungsform für Peptide, Verfahren zu deren Herstellung und Verwendung
US20020155084A1 (en) * 2000-06-02 2002-10-24 The Regents Of The University Of The Michigan Nanoemulsion formulations
CN1160122C (zh) * 2001-04-20 2004-08-04 清华大学 一种制备口服胰岛素油相制剂的方法
EP1455810B1 (fr) * 2001-12-14 2007-06-13 Jagotec Ag Formulation pharmaceutique contenant de la ciclosporine et son utilisation
PE20050596A1 (es) * 2003-12-19 2005-10-18 Novartis Ag Microemulsion que comprende un inhibidor renina
WO2005092370A1 (fr) 2004-03-22 2005-10-06 Solvay Pharmaceuticals Gmbh Compositions pharmaceutiques par voie orale a base de lipases, en particulier de pancreatine, contenant des tensioacitfs
US9743680B2 (en) * 2005-10-14 2017-08-29 Wild Flavors, Inc. Microemulsions for use in food and beverage products
EP1961412A1 (fr) 2006-12-27 2008-08-27 LEK Pharmaceuticals D.D. Systèmes auto-microémulsifiants pour l'administration de médicaments
JP2011504871A (ja) * 2007-06-01 2011-02-17 ノボ・ノルデイスク・エー／エス 固体又は半固体担体中にペプチド薬剤を含む自然に分散可能なプレコンセントレイト
EP2910571B1 (fr) 2008-03-18 2016-10-05 Novo Nordisk A/S Analogues de l'insuline acylés, stabilisés à la protéase
GB201107630D0 (en) * 2011-05-06 2011-06-22 Proxima Concepts Ltd Microemulsions
CN104364260B (zh) 2012-04-11 2017-02-22 诺和诺德股份有限公司 胰岛素制剂
TWI700092B (zh) 2016-12-16 2020-08-01 丹麥商諾佛．儂迪克股份有限公司 含胰島素醫藥組成物
WO2018159941A1 (fr) * 2017-03-02 2018-09-07 대화제약 주식회사 Composition pharmaceutique stable comprenant du zanamivir
KR101991661B1 (ko) * 2017-03-02 2019-06-21 대화제약 주식회사 자나미비르를 포함하는 안정한 약제학적 조성물

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
EP0278660A1 (fr) * 1987-02-03 1988-08-17 Stiefel Laboratories (Ireland) Limited Microémulsions
EP0387647A2 (fr) * 1989-03-13 1990-09-19 Desitin Arzneimittel GmbH Composition pharmaceutique à haute dispersion
WO1991018669A1 (fr) * 1990-06-08 1991-12-12 Affinity Biotech, Inc. Procede servant a preparer des microemulsions
WO1992018147A1 (fr) * 1991-04-19 1992-10-29 Affinity Biotech, Inc. Formulations de microemulsions a inversion de phase
WO1993002665A1 (fr) * 1991-07-26 1993-02-18 Smithkline Beecham Corporation Microemulsion huileuse
WO1993002664A1 (fr) * 1991-07-26 1993-02-18 Smithkline Beecham Corporation Micro-emulsion huileuse

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5110606A (en) * 1990-11-13 1992-05-05 Affinity Biotech, Inc. Non-aqueous microemulsions for drug delivery

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146499A (en) * 1976-09-18 1979-03-27 Rosano Henri L Method for preparing microemulsions
EP0278660A1 (fr) * 1987-02-03 1988-08-17 Stiefel Laboratories (Ireland) Limited Microémulsions
EP0387647A2 (fr) * 1989-03-13 1990-09-19 Desitin Arzneimittel GmbH Composition pharmaceutique à haute dispersion
WO1991018669A1 (fr) * 1990-06-08 1991-12-12 Affinity Biotech, Inc. Procede servant a preparer des microemulsions
WO1992018147A1 (fr) * 1991-04-19 1992-10-29 Affinity Biotech, Inc. Formulations de microemulsions a inversion de phase
WO1993002665A1 (fr) * 1991-07-26 1993-02-18 Smithkline Beecham Corporation Microemulsion huileuse
WO1993002664A1 (fr) * 1991-07-26 1993-02-18 Smithkline Beecham Corporation Micro-emulsion huileuse

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of WO9408605A1 *

Also Published As

Publication number Publication date
WO1994008605A1 (fr) 1994-04-28
EP0666752A1 (fr) 1995-08-16
JPH08502492A (ja) 1996-03-19

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Legal Events

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PUAI Public reference made under article 153(3) epc to a published international application that has entered the european phase

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Effective date: 19950510

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RHK1 Main classification (correction)

Ipc: A61K 37/00

A4 Supplementary search report drawn up and despatched

Effective date: 19960729

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18D Application deemed to be withdrawn

Effective date: 19990206