JPH0734015B2 - 微量成分の新規測定法 - Google Patents
微量成分の新規測定法Info
- Publication number
- JPH0734015B2 JPH0734015B2 JP1100970A JP10097089A JPH0734015B2 JP H0734015 B2 JPH0734015 B2 JP H0734015B2 JP 1100970 A JP1100970 A JP 1100970A JP 10097089 A JP10097089 A JP 10097089A JP H0734015 B2 JPH0734015 B2 JP H0734015B2
- Authority
- JP
- Japan
- Prior art keywords
- substance
- measured
- labeled
- complex
- binding
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/536—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase
- G01N33/537—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody
- G01N33/538—Immunoassay; Biospecific binding assay; Materials therefor with immune complex formed in liquid phase with separation of immune complex from unbound antigen or antibody by sorbent column, particles or resin strip, i.e. sorbent materials
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N2030/022—Column chromatography characterised by the kind of separation mechanism
- G01N2030/027—Liquid chromatography
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N30/00—Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
- G01N30/02—Column chromatography
- G01N30/04—Preparation or injection of sample to be analysed
- G01N30/06—Preparation
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/971—Capture of complex after antigen-antibody reaction
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
- Y10S436/812—Infectious mononucleosis
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/824—Immunological separation techniques
Landscapes
- Health & Medical Sciences (AREA)
- Immunology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Microbiology (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Sampling And Sample Adjustment (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP10179888 | 1988-04-25 | ||
JP63-101798 | 1988-04-25 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPH0228557A JPH0228557A (ja) | 1990-01-30 |
JPH0734015B2 true JPH0734015B2 (ja) | 1995-04-12 |
Family
ID=14310167
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1100970A Expired - Fee Related JPH0734015B2 (ja) | 1988-04-25 | 1989-04-20 | 微量成分の新規測定法 |
Country Status (5)
Country | Link |
---|---|
US (1) | US5545530A (fr) |
EP (1) | EP0357869B1 (fr) |
JP (1) | JPH0734015B2 (fr) |
AT (1) | ATE97495T1 (fr) |
DE (1) | DE68910758T2 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997011368A1 (fr) * | 1995-09-22 | 1997-03-27 | Asahi Denka Kogyo K.K. | Procede d'analyse pour allergene |
Families Citing this family (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69115518T2 (de) * | 1990-01-09 | 1996-08-29 | Wako Pure Chem Ind Ltd | Verfahren zur Abtrennung und Messung von Spurbestandteilen |
JP2994739B2 (ja) * | 1990-11-29 | 1999-12-27 | 和光純薬工業株式会社 | 微量成分の迅速測定方法 |
US5571729A (en) * | 1992-06-17 | 1996-11-05 | Wako Pure Chemical Industries, Ltd. | Process for separating complex |
ES2140511T3 (es) * | 1993-11-16 | 2000-03-01 | Wako Pure Chem Ind Ltd | Procedimiento para separar y medir glicoproteinas. |
CA2181109A1 (fr) | 1995-07-18 | 1997-01-19 | Nobuko Imajo | Polypeptide et methode pour mesurer les constituants provenant d'un organisme vivant |
US6005256A (en) * | 1998-02-12 | 1999-12-21 | Raytheon Company | Method and apparatus for performing cell analysis based on simultaneous multiple marker emissions from neoplasia (CASMMEN) |
US6471968B1 (en) | 2000-05-12 | 2002-10-29 | Regents Of The University Of Michigan | Multifunctional nanodevice platform |
CA2443320C (fr) | 2001-04-04 | 2010-01-26 | Wako Pure Chemical Industries Ltd. | Methode de separation par electrophorese d'une matiere cible basee sur l'affinite d'une substance contenant une chaine d'acide nucleique marquee |
US7442313B2 (en) * | 2003-08-27 | 2008-10-28 | Thinkvillage-Kerfoot, Llc | Environmental remediation method and system |
US7621696B2 (en) * | 2006-07-12 | 2009-11-24 | Thinkvillage-Kerfoot, Llc | Directional microporous diffuser and directional sparging |
US7569140B2 (en) * | 2005-11-10 | 2009-08-04 | Thinkvillage-Kerfoot, Llc | Directional spargewell system |
US8771507B2 (en) | 2003-12-24 | 2014-07-08 | Thinkvillage-Kerfoot, Llc | Directional microporous diffuser and directional sparging |
WO2005115477A2 (fr) | 2004-04-13 | 2005-12-08 | Quintessence Biosciences, Inc. | Conjugues de ribonuclease non naturelle utilises en tant qu'agents cytotoxiques |
US20090104119A1 (en) * | 2004-08-25 | 2009-04-23 | Majoros Istvan J | Dendrimer Based Compositions And Methods Of Using The Same |
US20070041934A1 (en) * | 2005-08-12 | 2007-02-22 | Regents Of The University Of Michigan | Dendrimer based compositions and methods of using the same |
US8840882B2 (en) * | 2006-06-23 | 2014-09-23 | Quintessence Biosciences, Inc. | Modified ribonucleases |
JP2009543868A (ja) | 2006-07-17 | 2009-12-10 | クインテセンス バイオサイエンシーズ インコーポレーティッド | 癌治療に関する方法および組成物 |
AU2008275501A1 (en) * | 2007-04-19 | 2009-01-15 | The Regents Of The University Of Michigan | Dendrimer based compositions and methods of using the same |
US9175015B2 (en) * | 2007-08-22 | 2015-11-03 | Colorado School Of Mines | Gold nanoparticle conjugates and uses thereof |
US8697062B2 (en) * | 2007-10-08 | 2014-04-15 | Quintessence Biosciences, Inc. | Compositions and methods for ribonuclease-based therapeutics |
US8252834B2 (en) | 2008-03-12 | 2012-08-28 | The Regents Of The University Of Michigan | Dendrimer conjugates |
WO2010096464A1 (fr) | 2009-02-18 | 2010-08-26 | Boyes Stephen G | Conjugués de nanoparticules d'or/lanthanide et leurs utilisations |
WO2010039861A2 (fr) | 2008-09-30 | 2010-04-08 | The Regents Of The University Of Michigan | Conjugués de dendrimères |
JP2012504423A (ja) | 2008-10-01 | 2012-02-23 | クインテッセンス バイオサイエンシズ,インコーポレーテッド | 治療用リボヌクレアーゼ |
US9173840B2 (en) | 2008-10-09 | 2015-11-03 | Northeastern University | Multifunctional self-assembling polymeric nanosystems |
US9017644B2 (en) | 2008-11-07 | 2015-04-28 | The Regents Of The University Of Michigan | Methods of treating autoimmune disorders and/or inflammatory disorders |
US8945508B2 (en) | 2009-10-13 | 2015-02-03 | The Regents Of The University Of Michigan | Dendrimer compositions and methods of synthesis |
US8912323B2 (en) | 2009-10-30 | 2014-12-16 | The Regents Of The University Of Michigan | Multifunctional small molecules |
SG189391A1 (en) * | 2010-10-18 | 2013-05-31 | Nestec Sa | Methods for determining anti-drug antibody isotypes |
WO2013085718A1 (fr) | 2011-12-08 | 2013-06-13 | The Regents Of The University Of Michigan | Petites molécules multifonctionnelles |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL42105A (en) * | 1973-04-25 | 1976-08-31 | Yissum Res Dev Co | Process for determination of triiodothyronine |
IL51224A (en) * | 1976-11-19 | 1979-09-30 | Ames Yissum Ltd | Assay method for the quanititative determination of a hapten in aqueous solution |
US4145406A (en) * | 1977-04-11 | 1979-03-20 | Miles Laboratories, Inc. | Specific binding - adsorbent assay method and test means |
US4235869A (en) * | 1978-05-16 | 1980-11-25 | Syva Company | Assay employing a labeled Fab-fragment ligand complex |
US4371515A (en) * | 1978-12-26 | 1983-02-01 | E-Y Laboratories, Inc. | Method for forming an isolated lectin-immunological conjugate |
US4347058A (en) * | 1980-09-15 | 1982-08-31 | Beckman Instruments, Inc. | Thyroid polarization fluoroimmunoassay |
EP0073593A1 (fr) * | 1981-09-01 | 1983-03-09 | E.I. Du Pont De Nemours And Company | Immuno-essai hétérogène utilisant le tamisage moléculaire |
US4496654A (en) * | 1983-04-08 | 1985-01-29 | Quidel | Detection of HCG with solid phase support having avidin coating |
DE3342627A1 (de) * | 1983-11-25 | 1985-06-05 | Boehringer Mannheim Gmbh, 6800 Mannheim | Immunchemischer schnelltest |
JPH0610678B2 (ja) * | 1984-11-05 | 1994-02-09 | オリンパス光学工業株式会社 | 免疫学的分析方法 |
JPS61120058A (ja) * | 1984-11-16 | 1986-06-07 | Hitachi Ltd | 目的成分の分析方法及びその装置 |
US4670381A (en) * | 1985-07-19 | 1987-06-02 | Eastman Kodak Company | Heterogeneous immunoassay utilizing horizontal separation in an analytical element |
-
1989
- 1989-04-20 JP JP1100970A patent/JPH0734015B2/ja not_active Expired - Fee Related
- 1989-04-24 DE DE68910758T patent/DE68910758T2/de not_active Expired - Lifetime
- 1989-04-24 EP EP89107393A patent/EP0357869B1/fr not_active Expired - Lifetime
- 1989-04-24 AT AT89107393T patent/ATE97495T1/de not_active IP Right Cessation
-
1995
- 1995-05-17 US US08/442,986 patent/US5545530A/en not_active Expired - Lifetime
Non-Patent Citations (2)
Title |
---|
J.Pharmacol.Exp.Ther.,206(1),P.158−66,(1978) |
Methcdol.Anal.Toxical,3,P.135−46(1985) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997011368A1 (fr) * | 1995-09-22 | 1997-03-27 | Asahi Denka Kogyo K.K. | Procede d'analyse pour allergene |
Also Published As
Publication number | Publication date |
---|---|
DE68910758T2 (de) | 1994-05-26 |
JPH0228557A (ja) | 1990-01-30 |
US5545530A (en) | 1996-08-13 |
DE68910758D1 (de) | 1993-12-23 |
EP0357869A1 (fr) | 1990-03-14 |
EP0357869B1 (fr) | 1993-11-18 |
ATE97495T1 (de) | 1993-12-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPH0734015B2 (ja) | 微量成分の新規測定法 | |
US4228237A (en) | Methods for the detection and determination of ligands | |
CN112285038B (zh) | 6-磷酸葡萄糖脱氢酶突变体及其在制备洋地黄毒苷检测试剂中的用途 | |
JPH08506907A (ja) | アシル化タンパク質凝集体および免疫検定における干渉の抑制についてのそれらの使用 | |
US4478934A (en) | Determination of adenosine by immunoassay involving acylation of the adenosine | |
JPH05184383A (ja) | 二重特異性抗体 | |
US5792606A (en) | Nucleic acid hybridization based assay for determining a substance of interest | |
CN115856278B (zh) | 妥布霉素检测试剂盒 | |
EP0088974A2 (fr) | Essai immunologique homogène avec un anti-réactif marqué monoclonal | |
JP3400507B2 (ja) | 特異的結合パートナーと炭水化物含有蛋白質から構成される複合体の製造方法 | |
JP2994739B2 (ja) | 微量成分の迅速測定方法 | |
JPH0666800A (ja) | 複合体の分離方法 | |
EP0685740B1 (fr) | Dosage par liaison spécifique sans séparation avec des anticorps anti-inhibiteurs | |
EP0184701B1 (fr) | Procédé pour déterminer un ligand | |
JP2949637B2 (ja) | 二重特異性抗体を用いる測定方法 | |
JP3376955B2 (ja) | 複合体の分離方法 | |
Yamamoto et al. | The Effect of Immunization with Protein‐sulphanilic Acid Conjugate on Sulphanilic Acid Disposition in the Rat | |
JPH09127109A (ja) | 抗−2′−デオキシシチジン抗体並びにその製造及び使用 | |
JP2000146969A (ja) | 微量成分の迅速測定方法 | |
JPH04320965A (ja) | 微量成分の測定方法 | |
JPH0466870A (ja) | 新規な標識体及びそれを用いた免疫測定法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
LAPS | Cancellation because of no payment of annual fees |