JPH0686476B2 - アルコキシメチリデンエピポドフィロトキシングルコシド - Google Patents

アルコキシメチリデンエピポドフィロトキシングルコシド

Info

Publication number
JPH0686476B2
JPH0686476B2 JP2313797A JP31379790A JPH0686476B2 JP H0686476 B2 JPH0686476 B2 JP H0686476B2 JP 2313797 A JP2313797 A JP 2313797A JP 31379790 A JP31379790 A JP 31379790A JP H0686476 B2 JPH0686476 B2 JP H0686476B2
Authority
JP
Japan
Prior art keywords
compound
formula
hydrogen
alkoxy
demethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP2313797A
Other languages
English (en)
Japanese (ja)
Other versions
JPH03170494A (ja
Inventor
毅 大沼
隆之 内藤
英夫 亀井
Original Assignee
ブリストル―マイアーズ スクイブ コムパニー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ブリストル―マイアーズ スクイブ コムパニー filed Critical ブリストル―マイアーズ スクイブ コムパニー
Publication of JPH03170494A publication Critical patent/JPH03170494A/ja
Publication of JPH0686476B2 publication Critical patent/JPH0686476B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00—Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06—Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
JP2313797A 1989-11-20 1990-11-19 アルコキシメチリデンエピポドフィロトキシングルコシド Expired - Lifetime JPH0686476B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/438,829 US5034380A (en) 1989-11-20 1989-11-20 Alkoxymethylidene epipodophyllotoxin glucosides
US438829 1989-11-20

Publications (2)

Publication Number Publication Date
JPH03170494A JPH03170494A (ja) 1991-07-24
JPH0686476B2 true JPH0686476B2 (ja) 1994-11-02

Family

ID=23742200

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2313797A Expired - Lifetime JPH0686476B2 (ja) 1989-11-20 1990-11-19 アルコキシメチリデンエピポドフィロトキシングルコシド

Country Status (15)

Country Link
US (1) US5034380A (de)
EP (1) EP0433678A1 (de)
JP (1) JPH0686476B2 (de)
KR (1) KR930007382B1 (de)
AU (1) AU614698B2 (de)
CA (1) CA2029748A1 (de)
FI (1) FI905685A (de)
HU (1) HU208019B (de)
IE (1) IE904162A1 (de)
IL (1) IL95884A (de)
NO (1) NO174204C (de)
NZ (1) NZ236106A (de)
PT (1) PT95931A (de)
YU (1) YU220790A (de)
ZA (1) ZA909252B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW260671B (de) * 1991-04-29 1995-10-21 Bristol Myers Squibb Co
US5458299A (en) * 1993-11-17 1995-10-17 Collins; Kenneth Aircraft deicing apparatus
US6207673B1 (en) 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1171314A (fr) * 1955-05-13 1959-01-23 Sandoz Ag Produits de condensation de glucosides avec des composés carbonyliques et leur préparation
JPS61227590A (ja) * 1985-04-02 1986-10-09 Microbial Chem Res Found 新規４′−デメチル−４−エピポドフイロトキシン誘導体
US4916217A (en) * 1987-01-08 1990-04-10 Bristol-Myers Company Phosphorus containing derivatives of epipodophyllotoxin
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4912204A (en) * 1988-09-06 1990-03-27 Bristol-Myers Company Fluoro-substituted epipodophyllotoxin glucosides
DE3913326A1 (de) * 1989-04-22 1990-11-08 Behringwerke Ag Verfahren zur herstellung von etoposiden
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
JPH087254B2 (ja) * 1989-08-07 1996-01-29 富士通株式会社 半導体集積回路装置

Also Published As

Publication number Publication date
NO174204C (no) 1994-04-06
NO174204B (no) 1993-12-20
CA2029748A1 (en) 1991-05-21
EP0433678A1 (de) 1991-06-26
ZA909252B (en) 1991-09-25
NO904967L (no) 1991-05-21
NZ236106A (en) 1991-11-26
KR930007382B1 (ko) 1993-08-09
AU6671190A (en) 1991-05-23
IE904162A1 (en) 1991-05-22
FI905685A0 (fi) 1990-11-16
US5034380A (en) 1991-07-23
IL95884A0 (en) 1991-07-18
HU208019B (en) 1993-07-28
HUT55406A (en) 1991-05-28
AU614698B2 (en) 1991-09-05
KR910009720A (ko) 1991-06-28
NO904967D0 (no) 1990-11-16
JPH03170494A (ja) 1991-07-24
IL95884A (en) 1994-10-21
YU220790A (sh) 1992-09-07
FI905685A (fi) 1991-05-21
PT95931A (pt) 1991-09-13

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