NO174204C - Analogifremgangsmåte til fremstilling av et terapeutisk aktivt 4'-demetylepipodofyll toksinglukosid-derivat - Google Patents

Analogifremgangsmåte til fremstilling av et terapeutisk aktivt 4'-demetylepipodofyll toksinglukosid-derivat

Info

Publication number
NO174204C
NO174204C NO904967A NO904967A NO174204C NO 174204 C NO174204 C NO 174204C NO 904967 A NO904967 A NO 904967A NO 904967 A NO904967 A NO 904967A NO 174204 C NO174204 C NO 174204C
Authority
NO
Norway
Prior art keywords
demethylpipodophyll
toxin
preparing
therapeutically active
analogous process
Prior art date
Application number
NO904967A
Other languages
English (en)
Other versions
NO174204B (no
NO904967L (no
NO904967D0 (no
Inventor
Takeshi Ohnuma
Takayuki Naito
Hideo Kamei
Original Assignee
Bristol Myers Squibb Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Squibb Co filed Critical Bristol Myers Squibb Co
Publication of NO904967D0 publication Critical patent/NO904967D0/no
Publication of NO904967L publication Critical patent/NO904967L/no
Publication of NO174204B publication Critical patent/NO174204B/no
Publication of NO174204C publication Critical patent/NO174204C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • C07H3/06Oligosaccharides, i.e. having three to five saccharide radicals attached to each other by glycosidic linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04Heterocyclic radicals containing only oxygen as ring hetero atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
NO904967A 1989-11-20 1990-11-16 Analogifremgangsmåte til fremstilling av et terapeutisk aktivt 4'-demetylepipodofyll toksinglukosid-derivat NO174204C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/438,829 US5034380A (en) 1989-11-20 1989-11-20 Alkoxymethylidene epipodophyllotoxin glucosides

Publications (4)

Publication Number Publication Date
NO904967D0 NO904967D0 (no) 1990-11-16
NO904967L NO904967L (no) 1991-05-21
NO174204B NO174204B (no) 1993-12-20
NO174204C true NO174204C (no) 1994-04-06

Family

ID=23742200

Family Applications (1)

Application Number Title Priority Date Filing Date
NO904967A NO174204C (no) 1989-11-20 1990-11-16 Analogifremgangsmåte til fremstilling av et terapeutisk aktivt 4'-demetylepipodofyll toksinglukosid-derivat

Country Status (15)

Country Link
US (1) US5034380A (no)
EP (1) EP0433678A1 (no)
JP (1) JPH0686476B2 (no)
KR (1) KR930007382B1 (no)
AU (1) AU614698B2 (no)
CA (1) CA2029748A1 (no)
FI (1) FI905685A (no)
HU (1) HU208019B (no)
IE (1) IE904162A1 (no)
IL (1) IL95884A (no)
NO (1) NO174204C (no)
NZ (1) NZ236106A (no)
PT (1) PT95931A (no)
YU (1) YU220790A (no)
ZA (1) ZA909252B (no)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW260671B (no) * 1991-04-29 1995-10-21 Bristol Myers Squibb Co
US5458299A (en) * 1993-11-17 1995-10-17 Collins; Kenneth Aircraft deicing apparatus
US6207673B1 (en) 1997-03-12 2001-03-27 The University Of North Carolina At Chapel Hill Covalent conjugates of topoisomerase I and topoisomerase II inhibitors
AU775373B2 (en) 1999-10-01 2004-07-29 Immunogen, Inc. Compositions and methods for treating cancer using immunoconjugates and chemotherapeutic agents

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1171314A (fr) * 1955-05-13 1959-01-23 Sandoz Ag Produits de condensation de glucosides avec des composés carbonyliques et leur préparation
JPS61227590A (ja) * 1985-04-02 1986-10-09 Microbial Chem Res Found 新規4′−デメチル−4−エピポドフイロトキシン誘導体
US4916217A (en) * 1987-01-08 1990-04-10 Bristol-Myers Company Phosphorus containing derivatives of epipodophyllotoxin
US4904768A (en) * 1987-08-04 1990-02-27 Bristol-Myers Company Epipodophyllotoxin glucoside 4'-phosphate derivatives
US4912204A (en) * 1988-09-06 1990-03-27 Bristol-Myers Company Fluoro-substituted epipodophyllotoxin glucosides
DE3913326A1 (de) * 1989-04-22 1990-11-08 Behringwerke Ag Verfahren zur herstellung von etoposiden
US4965348A (en) * 1989-05-19 1990-10-23 Bristol-Myers Company Dimeric epipodophyllotoxin glucoside derivatives
US5036055A (en) * 1989-06-07 1991-07-30 Bristol-Myers Company Acylated derivatives of etoposide
JPH087254B2 (ja) * 1989-08-07 1996-01-29 富士通株式会社 半導体集積回路装置

Also Published As

Publication number Publication date
NO174204B (no) 1993-12-20
CA2029748A1 (en) 1991-05-21
EP0433678A1 (en) 1991-06-26
ZA909252B (en) 1991-09-25
NO904967L (no) 1991-05-21
NZ236106A (en) 1991-11-26
KR930007382B1 (ko) 1993-08-09
AU6671190A (en) 1991-05-23
IE904162A1 (en) 1991-05-22
FI905685A0 (fi) 1990-11-16
US5034380A (en) 1991-07-23
IL95884A0 (en) 1991-07-18
JPH0686476B2 (ja) 1994-11-02
HU208019B (en) 1993-07-28
HUT55406A (en) 1991-05-28
AU614698B2 (en) 1991-09-05
KR910009720A (ko) 1991-06-28
NO904967D0 (no) 1990-11-16
JPH03170494A (ja) 1991-07-24
IL95884A (en) 1994-10-21
YU220790A (sh) 1992-09-07
FI905685A (fi) 1991-05-21
PT95931A (pt) 1991-09-13

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