JPH06502400A - ４，５，６，７−テトラヒドロ−イミダゾ−（４，５，１ｊｋ）（１，４）−ベンゾジアゼピン−２−（１Ｈ）−チオン並びに中間生成物の製造方法 - Google Patents

４，５，６，７−テトラヒドロ−イミダゾ−（４，５，１ｊｋ）（１，４）−ベンゾジアゼピン−２−（１Ｈ）−チオン並びに中間生成物の製造方法

Info

Publication number
JPH06502400A
JPH06502400A JP3517660A JP51766091A JPH06502400A JP H06502400 A JPH06502400 A JP H06502400A JP 3517660 A JP3517660 A JP 3517660A JP 51766091 A JP51766091 A JP 51766091A JP H06502400 A JPH06502400 A JP H06502400A
Authority
JP
Japan
Prior art keywords
formula
tables
hydrogen
compound
formulas
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3517660A
Other languages
English (en)
Japanese (ja)
Inventor
ライナート，ハーバート
マーテンス，アルフレッド
Original Assignee
ベーリンガー　マンハイム　ゲーエムベーハー
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ベーリンガー　マンハイム　ゲーエムベーハー filed Critical ベーリンガー　マンハイム　ゲーエムベーハー
Publication of JPH06502400A publication Critical patent/JPH06502400A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06—Peri-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00—Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/26—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring
    • C07C211/29—Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing at least one six-membered aromatic ring the carbon skeleton being further substituted by halogen atoms or by nitro or nitroso groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
JP3517660A 1990-11-16 1991-10-29 ４，５，６，７−テトラヒドロ−イミダゾ−（４，５，１ｊｋ）（１，４）−ベンゾジアゼピン−２−（１Ｈ）−チオン並びに中間生成物の製造方法 Pending JPH06502400A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DE4036552A DE4036552C1 (pt) 1990-11-16 1990-11-16
DE4036552.2 1990-11-16
PCT/EP1991/002038 WO1992008706A1 (de) 1990-11-16 1991-10-29 Verfahren zur herstellung von 4,5,6,7-tetrahydro-imidazo-(4,5,ljk) (1,4)-benzodiazepin-2-(1h)-thionen sowie zwischenprodukte

Publications (1)

Publication Number Publication Date
JPH06502400A true JPH06502400A (ja) 1994-03-17

Family

ID=6418388

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3517660A Pending JPH06502400A (ja) 1990-11-16 1991-10-29 ４，５，６，７−テトラヒドロ−イミダゾ−（４，５，１ｊｋ）（１，４）−ベンゾジアゼピン−２−（１Ｈ）−チオン並びに中間生成物の製造方法

Country Status (9)

Country Link
EP (1) EP0557307A1 (pt)
JP (1) JPH06502400A (pt)
AU (1) AU8855991A (pt)
CA (1) CA2096238A1 (pt)
DE (1) DE4036552C1 (pt)
IE (1) IE913979A1 (pt)
IL (1) IL100033A0 (pt)
WO (1) WO1992008706A1 (pt)
ZA (1) ZA919050B (pt)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ238664A (en) * 1990-07-06 1992-12-23 Janssen Pharmaceutica Nv Substituted tetrahydroimidazo(1,4)benzodiazepin-2-(thi)ones and pharmaceutical anti-viral compositions
WO1993006106A1 (en) * 1991-09-24 1993-04-01 Janssen Pharmaceutica N.V. PROCESS FOR PREPARING ENANTIOMERICALLY PURE IMIDAZO[4,5,1-jk][1,4]-BENZODIAZEPIN-2(1H^_)-THIONES
UA56197C2 (uk) 1996-11-08 2003-05-15 Зенека Лімітед Гетероциклічні похідні

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8806449D0 (en) * 1988-03-18 1988-04-20 Janssen Pharmaceutica Nv Antiviral hexahydroimiazo(1 4)benzodiazepin-2-ones
IL93136A (en) * 1989-02-23 1995-01-24 Janssen Pharmaceutica Nv History of tetrahydroimidazo [1,4] benzodiazepine-2-thione, their preparation and pharmaceutical preparations containing them

Also Published As

Publication number Publication date
IE913979A1 (en) 1992-05-20
DE4036552C1 (pt) 1992-02-06
ZA919050B (en) 1992-08-26
EP0557307A1 (de) 1993-09-01
CA2096238A1 (en) 1992-05-17
AU8855991A (en) 1992-06-11
IL100033A0 (en) 1992-08-18
WO1992008706A1 (de) 1992-05-29

Similar Documents

Publication Publication Date Title
CA2160966C (fr) Derives de piperidine, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
CA1340074C (en) Benzodiazepines, process and intermediates for the preparation thereof and their applications in therapy
CN1331849C (zh) 甲砜霉素和氟苯尼考的新合成方法及其关键中间体
NL8000277A (nl) Nieuwe nor-tropaanverbindingen alsmede werkwijze ter bereiding en therapeutische toepassing van deze verbindingen.
JPH07505159A (ja) 置換グアニジンの製法
FR2536749A1 (fr) (amino-2 ethyl)-6 benzoxazolinones substituees, leur preparation et leurs applications en therapeutique
Wasserman et al. The use of β-lactams in the synthesis of spermine and spermidine alkaloids: Total synthesis of homaline
FR2674849A1 (fr) Nouveaux derives de n-cyclohexyl benzamides ou thiobenzamides, leurs preparations et leurs applications en therapeutique.
JPH06502400A (ja) ４，５，６，７−テトラヒドロ−イミダゾ−（４，５，１ｊｋ）（１，４）−ベンゾジアゼピン−２−（１Ｈ）−チオン並びに中間生成物の製造方法
CH641181A5 (fr) Indolo-quinolizidines, procede pour leur preparation et compositions therapeutiques les contenant.
CA2368815A1 (en) Novel synthesis and crystallization of piperazine ring-containing compounds
JPS5962595A (ja) ３，５，７―トリ置換―トリアゾロピリミジン誘導体
CN1052864A (zh) 喹诺酮化合物及其制备方法
CA1202974A (fr) Procede de preparation de nouvelles benzothiopyranopyridinones et de leurs sels
HU214869B (hu) Eljárás 11-helyettesített-20,21-dinoreburnamenin-származékok és a vegyületeket tartalmazó gyógyászati készítmények előállítására
JPH02178285A (ja) イミダゾキノキサリンの化学的製造方法および該方法に使用する中間体
JPS6026154B2 (ja) 塩基性オキサジン染料の製造法
KR0171221B1 (ko) N-2-클로로벤질-2-옥소 및 n-2-클로로벤질-2, 2-디옥소-1,2,3-옥사티아졸리딘 유도체, 그 제조방법 및 그로부터 합성되는 티에노 [3,2-c]피리딘 유도체의 제조방법
Dutcher et al. Gliotoxin, the antibiotic principle of Gliocladium fimbriatum. IV. The structure of gliotoxin: The action of selenium
NZ194467A (en) -(5-phenyl-2,3,4,4a,5,9b-hexahydro-trans-4a,9b-1h-pyrido (4,3-b) indol-2-yl)alkylamines
Carney et al. Investigations in Heterocycles. XVIII. The Synthesis of 1, 2-Disubstituted 5, 6, 7, 8-Tetrahydro-4-quinazolinethiones1
HU176277B (en) Process for producing cycloalkyl-amine derivatives
JPS6032779A (ja) ベンゾチアゼピン誘導体の新規製造法
JPH04108789A (ja) イミダゾベンゾジアゼピン類及びそれらの塩の新規の製造方法、新規のイミダゾベンゾジアゼピン類及びそれらの塩並びにそれらの薬剤としての使用
US3205236A (en) Process of preparation of /j-alkylated tryptamines