JPH0574587B2 - - Google Patents

Info

Publication number
JPH0574587B2
JPH0574587B2 JP60167999A JP16799985A JPH0574587B2 JP H0574587 B2 JPH0574587 B2 JP H0574587B2 JP 60167999 A JP60167999 A JP 60167999A JP 16799985 A JP16799985 A JP 16799985A JP H0574587 B2 JPH0574587 B2 JP H0574587B2
Authority
JP
Japan
Prior art keywords
formula
compound
salt
diisopropylbenzylidene
heterocyclic compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60167999A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6229570A (ja
Inventor
Naohiro Imai
Tadayoshi Shiraishi
Ikuo Katsumi
Katsuji Yamashita
Yutaka Ariki
Toshiaki Yamashita
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kanegafuchi Chemical Industry Co Ltd
Original Assignee
Kanegafuchi Chemical Industry Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kanegafuchi Chemical Industry Co Ltd filed Critical Kanegafuchi Chemical Industry Co Ltd
Priority to JP16799985A priority Critical patent/JPS6229570A/ja
Publication of JPS6229570A publication Critical patent/JPS6229570A/ja
Publication of JPH0574587B2 publication Critical patent/JPH0574587B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Thiazole And Isothizaole Compounds (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pyrrole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
JP16799985A 1985-07-29 1985-07-29 ３，５−ジイソプロピルベンジリデン複素環式化合物 Granted JPS6229570A (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP16799985A JPS6229570A (ja) 1985-07-29 1985-07-29 ３，５−ジイソプロピルベンジリデン複素環式化合物

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP16799985A JPS6229570A (ja) 1985-07-29 1985-07-29 ３，５−ジイソプロピルベンジリデン複素環式化合物

Publications (2)

Publication Number Publication Date
JPS6229570A JPS6229570A (ja) 1987-02-07
JPH0574587B2 true JPH0574587B2 (enrdf_load_html_response) 1993-10-18

Family

ID=15859921

Family Applications (1)

Application Number Title Priority Date Filing Date
JP16799985A Granted JPS6229570A (ja) 1985-07-29 1985-07-29 ３，５−ジイソプロピルベンジリデン複素環式化合物

Country Status (1)

Country Link
JP (1) JPS6229570A (enrdf_load_html_response)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4897406A (en) * 1987-11-13 1990-01-30 Nisshin Flour Milling Co., Ltd. Rhodanine derivatives and pharmaceutical compositions
US5208250A (en) * 1988-05-25 1993-05-04 Warner-Lambert Company Known and selected novel arylmethylenyl derivatives of thiazolidinones, imidazolidinones and oxazolidinones useful as antiallergy agents and anti-inflammatory agents
US5306822A (en) * 1988-05-25 1994-04-26 Warner-Lambert Company Arylmethylenyl derivatives of oxazolidinone
US5143928A (en) * 1990-03-27 1992-09-01 Warner-Lambert Company 3,5-di-tertiarybutyl-4-hydroxyphenylmethylene derivatives of 2-substituted thiazolidinones, oxazolidinones, and imidazolidinones as antiinflammatory agents
EP0525197B1 (en) * 1991-01-21 1997-08-27 Shionogi Seiyaku Kabushiki Kaisha 3-benzylidene-1-carbamoyl-2-pyrrolidone analogs
FR2694004B1 (fr) * 1992-07-21 1994-08-26 Adir Nouvelles 3-(Hydroxybenzylidényl)-indoline-2-ones et 3-(hydroxybenzylidényl)-indoline-2-thiones, leurs procédés de préparation, et les compositions pharmaceutiques qui les contiennent.
US5880141A (en) * 1995-06-07 1999-03-09 Sugen, Inc. Benzylidene-Z-indoline compounds for the treatment of disease
US6147106A (en) 1997-08-20 2000-11-14 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
US6906093B2 (en) 1995-06-07 2005-06-14 Sugen, Inc. Indolinone combinatorial libraries and related products and methods for the treatment of disease
EP0779282A1 (en) * 1995-12-14 1997-06-18 Eli Lilly And Company Thiomorpholinone compounds for treating multiple sclerosis
AU708167B2 (en) * 1996-01-17 1999-07-29 Taiho Pharmaceutical Co., Ltd. Intimal hypertrophy inhibitors
US6423708B1 (en) 1996-09-30 2002-07-23 Pfizer Inc Aralkyl and aralkylidene heterocyclic lactams and imides
UA56185C2 (uk) 1996-09-30 2003-05-15 Пфайзер Інк. Аралкіл- та аралкіліденгетероциклічні лактами та іміди, фармацевтична композиція та спосіб лікування
US6531502B1 (en) 1998-01-21 2003-03-11 Sugen, Inc. 3-Methylidenyl-2-indolinone modulators of protein kinase
US6569868B2 (en) 1998-04-16 2003-05-27 Sugen, Inc. 2-indolinone derivatives as modulators of protein kinase activity
WO2001009121A2 (en) * 1999-07-30 2001-02-08 Basf Aktiengesellschaft 2-pyrazolin-5-ones_as tyrosine kinase inhibitors
DK1255752T3 (da) 2000-02-15 2007-11-26 Sugen Inc Pyrrolsubstituerede 2-indolinonproteinkinaseinhibitorer
TWI270545B (en) 2000-05-24 2007-01-11 Sugen Inc Mannich base prodrugs of 3-(pyrrol-2-ylmethylidene)-2-indolinone derivatives
CA2410509A1 (en) 2000-06-02 2001-12-13 Sugen, Inc. Indolinone derivatives as protein kinase/phosphatase inhibitors
GB0013655D0 (en) * 2000-06-05 2000-07-26 Prolifix Ltd Therapeutic compounds
AR042586A1 (es) 2001-02-15 2005-06-29 Sugen Inc 3-(4-amidopirrol-2-ilmetiliden)-2-indolinona como inhibidores de la protein quinasa; sus composiciones farmaceuticas; un metodo para la modulacion de la actividad catalitica de la proteinquinasa; un metodo para tratar o prevenir una afeccion relacionada con la proteinquinasa
PE20030062A1 (es) 2001-05-30 2003-02-08 Sugen Inc Derivados aralquilsulfonil-3-(pirrol-2-ilmetiliden)-2-indolinona como inhibidores de quinasas

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5879944A (ja) * 1981-11-09 1983-05-13 Kanegafuchi Chem Ind Co Ltd ３，５−ジ・タ−シヤリ−・ブチルスチレン誘導体及び抗炎症、鎮痛、解熱剤並びに血小板凝集阻害剤
JPS57130950A (en) * 1981-02-05 1982-08-13 Kanegafuchi Chem Ind Co Ltd 3,5-di-tert-butyl-4-hydroxystyrene derivative and anti- inflammatory, analgesic, antipyretic agent and inhibitor for blood platelet aggregation

Also Published As

Publication number Publication date
JPS6229570A (ja) 1987-02-07

Similar Documents

Publication Publication Date Title
JPH0574587B2 (enrdf_load_html_response)
AU656615B2 (en) Inhibitors of HIV reverse transcriptase
KR100708783B1 (ko) Ｎｏｓ 억제제로서의 ｎ-헤테로시클릭 유도체
US4234595A (en) 3-Indolyl-tertiary butylaminopropanols
KR19990063987A (ko) 신규 헤테로시클릭 유도체 및 이것의 의약 용도
JP2572115B2 (ja) 抗増殖剤として有用な５−アミノ又は置換アミノ−１，２，３− トリアゾール類
KR20060015283A (ko) 신규한 피리도피라진 및 키나제 억제제로서의 이의 용도
JPS62111962A (ja) ３−フエニルチオメチルスチレン誘導体
EP0491218A1 (en) Benzodiazepinones
JPH0369910B2 (enrdf_load_html_response)
FI86175B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara fenolderivat.
JP2001525399A (ja) 選択的β３アドレナリン作動性作動薬
EP0608568B1 (en) Aminocycloalkanobenzodioxoles as beta-3 selective adrenergic agents
JP5894164B2 (ja) クロメン誘導体
US4363808A (en) N-(3-Phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines
JPH01294670A (ja) ２−（ピペラジニル）−２−オキソエチレン−置換フラボノイド誘導体、その製法およびそれを含有する医薬組成物
JPH0523262B2 (enrdf_load_html_response)
CA2727669A1 (fr) Nouveaux derives de (piperazinyl ponte)-1-alcanone et leur utilisation comme inhibiteurs de p75
EP1020451B1 (en) Anilide compounds and drugs containing the same
JPS62187439A (ja) 置換ピペラジン−１，４−ナフタレンジオン類
EP2419408A1 (en) 3-aryl or heteroaryl-substituted indole derivative
TW206230B (enrdf_load_html_response)
US4434174A (en) Treating cardiovascular diseases with N-(3-phenoxy-2-hydroxypropyl)benzimidazole-1-alkanamines
JPS6183179A (ja) 新規フラボン誘導体
JPH08217672A (ja) キサントン誘導体を含有する抗ヘリコバクター・ピロリ薬