JPH05508162A - イソニトリルリガンド含有金属―放射性核種錯化合物 - Google Patents

イソニトリルリガンド含有金属―放射性核種錯化合物

Info

Publication number
JPH05508162A
JPH05508162A JP91515592A JP51559291A JPH05508162A JP H05508162 A JPH05508162 A JP H05508162A JP 91515592 A JP91515592 A JP 91515592A JP 51559291 A JP51559291 A JP 51559291A JP H05508162 A JPH05508162 A JP H05508162A
Authority
JP
Japan
Prior art keywords
metal
radionuclide
formula
kit
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP91515592A
Other languages
English (en)
Japanese (ja)
Inventor
ヴェルブリュッゲン，アルフォン・エム
Original Assignee
マリンクロッド・メディカル・インコーポレイテッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by マリンクロッド・メディカル・インコーポレイテッド filed Critical マリンクロッド・メディカル・インコーポレイテッド
Publication of JPH05508162A publication Critical patent/JPH05508162A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F13/00—Compounds containing elements of Groups 7 or 17 of the Periodic Table
    • C07F13/005—Compounds without a metal-carbon linkage
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
    • A61K51/0476—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from monodendate ligands, e.g. sestamibi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
JP91515592A 1990-06-18 1991-06-14 イソニトリルリガンド含有金属―放射性核種錯化合物 Pending JPH05508162A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
AT90201569.2 1990-06-18
EP90201569 1990-06-18
PCT/US1991/004251 WO1991019516A1 (en) 1990-06-18 1991-06-14 Metal-radionuclide complex comprising isonitrile ligands

Publications (1)

Publication Number Publication Date
JPH05508162A true JPH05508162A (ja) 1993-11-18

Family

ID=8205034

Family Applications (1)

Application Number Title Priority Date Filing Date
JP91515592A Pending JPH05508162A (ja) 1990-06-18 1991-06-14 イソニトリルリガンド含有金属―放射性核種錯化合物

Country Status (5)

Country Link
EP (1) EP0548245A1 (enExample)
JP (1) JPH05508162A (enExample)
AU (1) AU8542591A (enExample)
CA (1) CA2085364A1 (enExample)
WO (1) WO1991019516A1 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003534388A (ja) * 2000-06-02 2003-11-18 ボード・オブ・リージェンツ，ザ・ユニヴァーシティ・オヴ・テキサス・システム エチレンジシステイン（ｅｃ）−薬物結合体
US10814013B2 (en) 2006-10-05 2020-10-27 The Board Of Regents Of The University Of Texas System Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2679452B1 (fr) * 1991-07-22 1993-11-12 Cis Bio International Produit radiopharmaceutique ayant notamment un tropisme cerebral, comportant un complexe nitruro d'un metal de transition, et son procede de preparation.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1305160C (en) * 1985-12-23 1992-07-14 Paul Louis Bergstein Ether isonitriles and radiolabeled complexes thereof
US4885100A (en) * 1987-09-11 1989-12-05 E. I. Du Pont De Nemours And Company Tris(isonitrile)copper(I) adducts for preparing radionuclide complexes

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2003534388A (ja) * 2000-06-02 2003-11-18 ボード・オブ・リージェンツ，ザ・ユニヴァーシティ・オヴ・テキサス・システム エチレンジシステイン（ｅｃ）−薬物結合体
US10814013B2 (en) 2006-10-05 2020-10-27 The Board Of Regents Of The University Of Texas System Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications
US10925977B2 (en) 2006-10-05 2021-02-23 Ceil>Point, LLC Efficient synthesis of chelators for nuclear imaging and radiotherapy: compositions and applications

Also Published As

Publication number Publication date
WO1991019516A1 (en) 1991-12-26
CA2085364A1 (en) 1991-12-19
EP0548245A1 (en) 1993-06-30
EP0548245A4 (enExample) 1994-01-26
AU8542591A (en) 1992-01-07

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