JPH0549618B2 - - Google Patents
Info
- Publication number
- JPH0549618B2 JPH0549618B2 JP62172445A JP17244587A JPH0549618B2 JP H0549618 B2 JPH0549618 B2 JP H0549618B2 JP 62172445 A JP62172445 A JP 62172445A JP 17244587 A JP17244587 A JP 17244587A JP H0549618 B2 JPH0549618 B2 JP H0549618B2
- Authority
- JP
- Japan
- Prior art keywords
- powder
- phosphate
- hydroxyapatite
- calcium phosphate
- ratio
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 claims description 31
- 238000004519 manufacturing process Methods 0.000 claims description 24
- 239000000843 powder Substances 0.000 claims description 23
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims description 22
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims description 22
- 239000001506 calcium phosphate Substances 0.000 claims description 19
- 229910000389 calcium phosphate Inorganic materials 0.000 claims description 17
- 235000011010 calcium phosphates Nutrition 0.000 claims description 16
- 239000000203 mixture Substances 0.000 claims description 16
- 239000011575 calcium Substances 0.000 claims description 13
- GBNXLQPMFAUCOI-UHFFFAOYSA-H tetracalcium;oxygen(2-);diphosphate Chemical compound [O-2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O GBNXLQPMFAUCOI-UHFFFAOYSA-H 0.000 claims description 13
- 238000010304 firing Methods 0.000 claims description 12
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 9
- 238000000034 method Methods 0.000 description 9
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 239000002994 raw material Substances 0.000 description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- 238000002441 X-ray diffraction Methods 0.000 description 4
- 238000002156 mixing Methods 0.000 description 4
- 229910000147 aluminium phosphate Inorganic materials 0.000 description 3
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 description 3
- 239000000920 calcium hydroxide Substances 0.000 description 3
- 229910001861 calcium hydroxide Inorganic materials 0.000 description 3
- 239000004568 cement Substances 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 150000007524 organic acids Chemical class 0.000 description 3
- RGHNJXZEOKUKBD-UHFFFAOYSA-N D-gluconic acid Natural products OCC(O)C(O)C(O)C(O)C(O)=O RGHNJXZEOKUKBD-UHFFFAOYSA-N 0.000 description 2
- RGHNJXZEOKUKBD-SQOUGZDYSA-N Gluconic acid Natural products OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C(O)=O RGHNJXZEOKUKBD-SQOUGZDYSA-N 0.000 description 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- JUNWLZAGQLJVLR-UHFFFAOYSA-J calcium diphosphate Chemical compound [Ca+2].[Ca+2].[O-]P([O-])(=O)OP([O-])([O-])=O JUNWLZAGQLJVLR-UHFFFAOYSA-J 0.000 description 2
- 229940043256 calcium pyrophosphate Drugs 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 238000010586 diagram Methods 0.000 description 2
- 235000019821 dicalcium diphosphate Nutrition 0.000 description 2
- 239000000174 gluconic acid Substances 0.000 description 2
- 235000012208 gluconic acid Nutrition 0.000 description 2
- 238000000227 grinding Methods 0.000 description 2
- 238000006460 hydrolysis reaction Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 229910000391 tricalcium phosphate Inorganic materials 0.000 description 2
- 235000019731 tricalcium phosphate Nutrition 0.000 description 2
- 229940078499 tricalcium phosphate Drugs 0.000 description 2
- 239000002253 acid Substances 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 229910052586 apatite Inorganic materials 0.000 description 1
- 239000012620 biological material Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- BRPQOXSCLDDYGP-UHFFFAOYSA-N calcium oxide Chemical compound [O-2].[Ca+2] BRPQOXSCLDDYGP-UHFFFAOYSA-N 0.000 description 1
- 239000000292 calcium oxide Substances 0.000 description 1
- ODINCKMPIJJUCX-UHFFFAOYSA-N calcium oxide Inorganic materials [Ca]=O ODINCKMPIJJUCX-UHFFFAOYSA-N 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000012790 confirmation Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 235000011187 glycerol Nutrition 0.000 description 1
- 230000020169 heat generation Effects 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 1
- 238000000197 pyrolysis Methods 0.000 description 1
- 238000003746 solid phase reaction Methods 0.000 description 1
- 239000000243 solution Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 238000005979 thermal decomposition reaction Methods 0.000 description 1
Landscapes
- Materials For Medical Uses (AREA)
- Dental Preparations (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62172445A JPS6418949A (en) | 1987-07-10 | 1987-07-10 | Production of powder agent for calcium phosphate based hardened body |
| EP88110950A EP0298501B1 (fr) | 1987-07-10 | 1988-07-08 | Composition pour la fabrication d'un matériau durcissable du type phosphate de calcium et procédé pour la production d'un tel matériau |
| DE3855611T DE3855611T2 (de) | 1987-07-10 | 1988-07-08 | Verfahren zur Herstellung eines kalziumphosphatartigen Pulvers |
| DE8888110950T DE3869850D1 (de) | 1987-07-10 | 1988-07-08 | Zusammensetzung zur herstellung eines haertbaren kalziumphosphatartigen materials und verfahren zur produktion eines derartigen materials. |
| EP91102716A EP0436499B1 (fr) | 1987-07-10 | 1988-07-08 | Procédé pour la production d'une poudre du type phosphate de calcium |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62172445A JPS6418949A (en) | 1987-07-10 | 1987-07-10 | Production of powder agent for calcium phosphate based hardened body |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6418949A JPS6418949A (en) | 1989-01-23 |
| JPH0549618B2 true JPH0549618B2 (fr) | 1993-07-26 |
Family
ID=15942115
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62172445A Granted JPS6418949A (en) | 1987-07-10 | 1987-07-10 | Production of powder agent for calcium phosphate based hardened body |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6418949A (fr) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5776669A (en) * | 1990-06-28 | 1998-07-07 | Eastman Kodak Company | Phenol substituted pyrazolo 1, 5-a benzimidazole couplers |
| JP2537121B2 (ja) * | 1992-12-04 | 1996-09-25 | 光雄 近藤 | 硬化性組成物 |
| MY169686A (en) * | 2011-01-27 | 2019-05-13 | Sirim Berhad | A method of converting limestone into tri-calcium phosphate and tetra-calcium phosphate powder simultaneously |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56166843A (en) * | 1980-05-28 | 1981-12-22 | Mitsubishi Mining & Cement Co | Filler for bone broken section and void section |
| JPS63115567A (ja) * | 1986-11-04 | 1988-05-20 | 住友大阪セメント株式会社 | 人工関節固定材料 |
-
1987
- 1987-07-10 JP JP62172445A patent/JPS6418949A/ja active Granted
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS56166843A (en) * | 1980-05-28 | 1981-12-22 | Mitsubishi Mining & Cement Co | Filler for bone broken section and void section |
| JPS63115567A (ja) * | 1986-11-04 | 1988-05-20 | 住友大阪セメント株式会社 | 人工関節固定材料 |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6418949A (en) | 1989-01-23 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US5496399A (en) | Storage stable calcium phosphate cements | |
| US5137534A (en) | Method for producing dental and medical bone prosthesis and bone prosthesis produced thereby | |
| EP0436499A2 (fr) | Procédé pour la production d'une poudre du type phosphate de calcium | |
| JPH0369844B2 (fr) | ||
| JP2004026648A (ja) | α−およびβ−リン酸三カルシウム粉末の製造方法 | |
| JP2563187B2 (ja) | リン酸カルシウム系硬化体の製造方法 | |
| JPH0549618B2 (fr) | ||
| JP2563186B2 (ja) | リン酸カルシウム系硬化体の製造方法 | |
| JPS5913443B2 (ja) | ＣａＯ−Ｐ↓２Ｏ↓５系アパタイトの製造法 | |
| JPS5951485B2 (ja) | ＣａＯ−Ｐ↓２Ｏ↓５系アパタイトの製造法 | |
| JPH0677598B2 (ja) | リン酸カルシウム系硬化体の製造用複合組成物及び硬化体の製造方法 | |
| JPS63159207A (ja) | 水酸アパタイトの製造方法 | |
| JPH02102165A (ja) | リン酸カルシウム系セラミックスの製造方法 | |
| JP2662984B2 (ja) | リン酸カルシウム系硬化体の製造用複合組成物及び硬化体の製造方法 | |
| JP2638619B2 (ja) | 自己硬化型高強度複合生体材料とその製造方法 | |
| JP3262233B2 (ja) | リン酸カルシウムの製造方法 | |
| JPH01301543A (ja) | 硬化性組成物 | |
| JPH05310410A (ja) | ストロンチウム水酸アパタイト粉体の製造法 | |
| KR0153988B1 (ko) | 졸-겔법을 이용한 수산화아파타이트의 제조방법 | |
| RU2431627C2 (ru) | Способ подготовки шихты для получения биокерамики | |
| JPH03210271A (ja) | リン酸カルシウム系生体材料の製造方法 | |
| JP2509254B2 (ja) | アパタイト被覆体の製造方法 | |
| RU2714188C1 (ru) | Способ получения окрашенного однофазного пирофосфата кальция | |
| JPH0324406B2 (fr) | ||
| JPH0292860A (ja) | 燐酸カルシウム成形体の製造方法 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |