JPH0535B2 - - Google Patents

Info

Publication number
JPH0535B2
JPH0535B2 JP62282943A JP28294387A JPH0535B2 JP H0535 B2 JPH0535 B2 JP H0535B2 JP 62282943 A JP62282943 A JP 62282943A JP 28294387 A JP28294387 A JP 28294387A JP H0535 B2 JPH0535 B2 JP H0535B2
Authority
JP
Japan
Prior art keywords
reactor
tube
liquid medium
capillary
citric acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP62282943A
Other languages
English (en)
Japanese (ja)
Other versions
JPS6471494A (en
Inventor
Namu Chan Hoo
Hyun Chon Bon
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
KANKOKU KAGAKU GIJUTSU KENKYUSHO
Original Assignee
KANKOKU KAGAKU GIJUTSU KENKYUSHO
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by KANKOKU KAGAKU GIJUTSU KENKYUSHO filed Critical KANKOKU KAGAKU GIJUTSU KENKYUSHO
Publication of JPS6471494A publication Critical patent/JPS6471494A/ja
Publication of JPH0535B2 publication Critical patent/JPH0535B2/ja
Granted legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/10Hollow fibers or tubes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M29/00Means for introduction, extraction or recirculation of materials, e.g. pumps
    • C12M29/16Hollow fibers
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14Fungi; Culture media therefor
    • C12N1/145Fungi isolates
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00Preparation of oxygen-containing organic compounds
    • C12P7/40Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/44Polycarboxylic acids
    • C12P7/48Tricarboxylic acids, e.g. citric acid
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12RINDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00Microorganisms ; Processes using microorganisms
    • C12R2001/645Fungi ; Processes using fungi
    • C12R2001/66Aspergillus
    • C12R2001/685Aspergillus niger
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/911Microorganisms using fungi
    • Y10S435/913Aspergillus
    • Y10S435/917Aspergillus niger

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Virology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP62282943A 1987-09-09 1987-11-09 Method for continuously manufacturing citric acid by reactor of double capillaries Granted JPS6471494A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
KR870009944A KR890005273A (ko) 1987-09-09 1987-09-09 2중 실관 반응기에 의한 구연산의 연속 생산방법

Publications (2)

Publication Number Publication Date
JPS6471494A JPS6471494A (en) 1989-03-16
JPH0535B2 true JPH0535B2 (enExample) 1993-01-05

Family

ID=19264327

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62282943A Granted JPS6471494A (en) 1987-09-09 1987-11-09 Method for continuously manufacturing citric acid by reactor of double capillaries

Country Status (3)

Country Link
US (1) US4910139A (enExample)
JP (1) JPS6471494A (enExample)
KR (1) KR890005273A (enExample)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5164081A (en) * 1989-03-24 1992-11-17 The Standard Oil Company Apparatus for separation and for treatment of fluid feedstreams, wafers for use therein and related methods
US5174900A (en) * 1989-03-24 1992-12-29 The Standard Oil Company Apparatus for separation and for treatment of fluid feedstreams, wafers for use therein and related methods
JPH02255079A (ja) * 1989-03-29 1990-10-15 Shimadzu Corp 細胞培養装置
JPH02276565A (ja) * 1989-04-18 1990-11-13 Japanese Res & Dev Assoc Bio Reactor Syst Food Ind 連続酵素反応装置
US5104799A (en) * 1990-10-05 1992-04-14 Haarmann & Reimer Method for the production of granular citric acid and salts thereof
US5045459A (en) * 1990-10-05 1991-09-03 Haarmann & Reimer Corp. Method for the production of granular citric acid
US5149643A (en) * 1990-10-05 1992-09-22 Haarmann & Beimer Method for the production of granular citric acid and salts thereof
US20070122904A1 (en) * 2000-09-29 2007-05-31 Unisearch Limited Method and apparatus for culturing cells
NZ525735A (en) * 2000-11-22 2005-07-29 Univ Maryland Use of CLyA hemolysin for excretion of proteins
US20060293261A1 (en) * 2005-06-24 2006-12-28 Taisho Pharmaceutical Co., Ltd. Clarithromycin or a salt thereof for the treatment or prevention of pulmonary disorders caused by the destruction of pulmonary alveoli
US8722374B2 (en) * 2005-06-30 2014-05-13 Synexa Life Science (Proprietary) Limited Production of secondary metabolites using capillary membranes
CA2726293C (en) 2008-06-03 2017-02-28 University Of Maryland, Baltimore Non-hemolytic clya for excretion of proteins
US8895291B2 (en) 2010-10-08 2014-11-25 Terumo Bct, Inc. Methods and systems of growing and harvesting cells in a hollow fiber bioreactor system with control conditions
WO2016049421A1 (en) 2014-09-26 2016-03-31 Terumo Bct, Inc. Scheduled feed
WO2017205667A1 (en) 2016-05-25 2017-11-30 Terumo Bct, Inc. Cell expansion
WO2018184028A2 (en) 2017-03-31 2018-10-04 Terumo Bct, Inc. Cell expansion
US11624046B2 (en) 2017-03-31 2023-04-11 Terumo Bct, Inc. Cell expansion

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SU907072A1 (ru) * 1980-06-30 1982-02-23 Ленинградский межотраслевой научно-исследовательский институт пищевой промышленности Способ получени лимонной кислоты
FR2507500A1 (fr) * 1981-06-12 1982-12-17 Dumont Engineering Et Cie Sa Dispositif pour agiter et aerer un liquide

Also Published As

Publication number Publication date
JPS6471494A (en) 1989-03-16
US4910139A (en) 1990-03-20
KR890005273A (ko) 1989-05-13

Similar Documents

Publication Publication Date Title
US4910139A (en) Method for continuously producing citric acid by dual hollow fiber membrane bioreactor
US4440853A (en) Microbiological methods using hollow fiber membrane reactor
SU1303035A3 (ru) Способ ферментации микроорганизмов @ @ дл получени клеток,содержащих поли- @ -оксимасл ную кислоту
Stenroos et al. Production of L-lactic acid with immobilized Lactobacillus delbrueckii
CN101509021B (zh) 一种吸附固定化发酵生产ε-聚赖氨酸的工艺
JPH0595778A (ja) 撹拌機を装備した多孔質分離膜一体型培養器
CN104229979B (zh) 一种mbr脱氮一体化装置及其应用
US3793154A (en) Apparatus for gaseous environmental control of batch cultures of micro-organisms
CN103642854B (zh) 谷氨酸棒杆菌固定化反复批次发酵产丁二酸的方法
Park et al. Itaconic acid production using an air-lift bioreactor in repeated batch culture of Aspergillus terreus
EP0125303A1 (en) Rapid production of biological products by fermentation in a densely-packed microbial membrane reactor
HÄggström et al. Continuous production of butanol with immobilized cells of Clostridium acetobutylicum
GARG et al. Continuous production of citric acid by immobilized whole cells of Aspergillus niger
JPS61209596A (ja) 固定化微生物による有機酸の製法
KR890004018B1 (ko) 전세포 효소를 세포 성장과 동시에 고정화하는 방법
JP2677602B2 (ja) 継代シード培養によるl−ソルボースの製造法およびそれに用いる装置
Takahashi et al. Diacetyl production by immobilized citrate-positive Lactococcus lactis subsp. lactis 3022 in the fibrous Ca-alginate gel
JPH09173090A (ja) L(+)−乳酸の製造法及びその製造装置
JP2006521801A (ja) 低濃度の炭素含有養分及び窒素含有養分を用いる発酵方法
Mussenden et al. Physiological studies related to the immobilization of Penicillium chrysogenum and penicillin production
CA1225610A (en) Rapid production of biological products by fermentation in a densely-packed microbial membrane reactor
JP4066287B2 (ja) 新規微生物およびそれを用いたエリスリトールの製造方法
Hwang et al. Biological conversion of rifamycin B by live Humicola sp. cells immobilized in a dual hollow fiber bioreactor
EP0102207A2 (en) Method of immobilizing enzymes
Melzoch et al. Lactic acid production by aggregated continuous cultures of Lactobacillus acidophilus under aerobic conditions