JPH05170797A - 環状ｈｉｖ主要中和決定基ペプチド - Google Patents

環状ｈｉｖ主要中和決定基ペプチド

Info

Publication number
JPH05170797A
JPH05170797A JP4006576A JP657692A JPH05170797A JP H05170797 A JPH05170797 A JP H05170797A JP 4006576 A JP4006576 A JP 4006576A JP 657692 A JP657692 A JP 657692A JP H05170797 A JPH05170797 A JP H05170797A
Authority
JP
Japan
Prior art keywords
peptide
amino acid
seq
hiv
cyclic
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP4006576A
Other languages
English (en)
Japanese (ja)
Inventor
Maria A Bednarek
エー．ベドナレク マリア
Richard L Tolman
エル．トルマン リチャード
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of JPH05170797A publication Critical patent/JPH05170797A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/64—Cyclic peptides containing only normal peptide links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00—Reverse transcribing RNA viruses
    • C12N2740/00011—Details
    • C12N2740/10011—Retroviridae
    • C12N2740/16011—Human Immunodeficiency Virus, HIV
    • C12N2740/16111—Human Immunodeficiency Virus, HIV concerning HIV env
    • C12N2740/16122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP4006576A 1991-12-19 1992-01-17 環状ｈｉｖ主要中和決定基ペプチド Pending JPH05170797A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80794391A 1991-12-19 1991-12-19
US807943 1991-12-19

Publications (1)

Publication Number Publication Date
JPH05170797A true JPH05170797A (ja) 1993-07-09

Family

ID=25197495

Family Applications (1)

Application Number Title Priority Date Filing Date
JP4006576A Pending JPH05170797A (ja) 1991-12-19 1992-01-17 環状ｈｉｖ主要中和決定基ペプチド

Country Status (3)

Country Link
EP (1) EP0551689A2 (enExample)
JP (1) JPH05170797A (enExample)
CA (1) CA2058876A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018522819A (ja) * 2015-05-11 2018-08-16 ヤンセン ファッシンズ アンド プリベンション ベーフェーＪａｎｓｓｅｎ Ｖａｃｃｉｎｅｓ ＆ Ｐｒｅｖｅｎｔｉｏｎ Ｂ．Ｖ． ペプチド模倣化合物を中和するインフルエンザウイルス

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000229997A (ja) * 1999-02-10 2000-08-22 Nissui Pharm Co Ltd 環状ペプチド及びエイズワクチン

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02174797A (ja) * 1988-09-09 1990-07-06 Asahi Glass Co Ltd ペプチド誘導体およびその用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL94558A0 (en) * 1989-06-06 1991-03-10 Merck & Co Inc Conjugate immunogen for aids and vaccine and pharmaceutical compositions containing it
IL98845A0 (en) * 1990-07-19 1992-07-15 Merck & Co Inc Coconjugate vaccines comprising immunogenic protein,hiv related peptides,and anionic moieties,their preparation and pharmaceutical compositions containing them
CA2047033A1 (en) * 1990-07-19 1992-01-20 Elizabeth E. Sugg Cyclic hiv principal neutralizing determinant peptides
CA2047031A1 (en) * 1990-07-19 1992-01-20 Stephen Marburg Peptide-polysaccharide-protein conjugate vaccines

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02174797A (ja) * 1988-09-09 1990-07-06 Asahi Glass Co Ltd ペプチド誘導体およびその用途

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2018522819A (ja) * 2015-05-11 2018-08-16 ヤンセン ファッシンズ アンド プリベンション ベーフェーＪａｎｓｓｅｎ Ｖａｃｃｉｎｅｓ ＆ Ｐｒｅｖｅｎｔｉｏｎ Ｂ．Ｖ． ペプチド模倣化合物を中和するインフルエンザウイルス

Also Published As

Publication number Publication date
EP0551689A3 (enExample) 1994-03-02
EP0551689A2 (en) 1993-07-21
CA2058876A1 (en) 1993-06-20

Similar Documents

Publication Publication Date Title
EP0467714A1 (en) The class II protein of the outer membrane of neisseria meningitidis
RU2201421C2 (ru) Синтетический пептид hiv (варианты), иммуногенная композиция для индукции иммунного ответа против пептидов hiv, диагностический набор для определения hiv-специфичных антител
US5606030A (en) Coconjugates of OMPC, HIV related peptides and anionic moieties
JP2002532387A (ja) ペプチドリガンドを介して結合された複数の免疫原性成分を有するｈｂｖコア抗原粒子
EP0550599B1 (en) Peptides for use in vaccination and induction of neutralizing antibodies against human immunodeficiency virus
EP0468714A2 (en) Peptide-polysaccharide-protein conjugate vaccines
JPH03128399A (ja) エイズ用複合免疫原
JPH05306299A (ja) ナイセリア・メニンギチジスの外膜のクラスｉｉ蛋白質とｈｉｖ−１関連ペプチドとの連結複合体、およびそれを含むワクチン
EP0166548A2 (en) Broad spectrum vaccine against gonorrhea
AU733234B2 (en) Conjugated peptides, immunological reagent containing same and use thereof for treatment of immunological disorders
CN100387616C (zh) 获得可增强特异交叉反应性的抗原结构的方法
JPH05170797A (ja) 環状ｈｉｖ主要中和決定基ペプチド
JPH04243896A (ja) 環状のｈｉｖ主要中和決定基ペプチド
US6258945B1 (en) HIV-1P-17 peptide fragments, compositions containing and methods for producing and using same
CA2050635A1 (en) Class ii protein of the outer membrane of neisseria meningitidis having immunologic carrier and enhancement properties, and vaccines containing same
GB2271995A (en) HIV peptide conjugated via anionic spacer to protein
JPH07145078A (ja) エイズワクチン
JPH05271276A (ja) 環式ｈｉｖ主要中和抗原決定基及びリポペプチドを含有する合成ペプチド
CA2085084A1 (en) Synthetic peptides comprising a cyclic hiv principal neutralizing determinant and a t-cell stimulatory epitope

Legal Events

Date Code Title Description
A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 19960119