JPH0476972B2 - - Google Patents
Info
- Publication number
- JPH0476972B2 JPH0476972B2 JP62192307A JP19230787A JPH0476972B2 JP H0476972 B2 JPH0476972 B2 JP H0476972B2 JP 62192307 A JP62192307 A JP 62192307A JP 19230787 A JP19230787 A JP 19230787A JP H0476972 B2 JPH0476972 B2 JP H0476972B2
- Authority
- JP
- Japan
- Prior art keywords
- drug
- weight
- parts
- water
- licorice
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000003814 drug Substances 0.000 claims description 56
- 229940079593 drug Drugs 0.000 claims description 32
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 28
- 208000018522 Gastrointestinal disease Diseases 0.000 claims description 20
- 241000411851 herbal medicine Species 0.000 claims description 19
- 239000000284 extract Substances 0.000 claims description 15
- 239000007788 liquid Substances 0.000 claims description 12
- 235000006200 Glycyrrhiza glabra Nutrition 0.000 claims description 10
- 238000009835 boiling Methods 0.000 claims description 10
- 238000002156 mixing Methods 0.000 claims description 10
- 235000001453 Glycyrrhiza echinata Nutrition 0.000 claims description 9
- 235000017382 Glycyrrhiza lepidota Nutrition 0.000 claims description 9
- 229940010454 licorice Drugs 0.000 claims description 9
- 241000202807 Glycyrrhiza Species 0.000 claims description 7
- 239000004480 active ingredient Substances 0.000 claims description 7
- 238000004519 manufacturing process Methods 0.000 claims description 6
- 244000303040 Glycyrrhiza glabra Species 0.000 claims 3
- 235000017443 Hedysarum boreale Nutrition 0.000 claims 1
- 235000007858 Hedysarum occidentale Nutrition 0.000 claims 1
- 239000001947 glycyrrhiza glabra rhizome/root Substances 0.000 claims 1
- 239000004615 ingredient Substances 0.000 claims 1
- 229940124597 therapeutic agent Drugs 0.000 description 20
- 208000024891 symptom Diseases 0.000 description 13
- 201000010099 disease Diseases 0.000 description 12
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 12
- 238000002560 therapeutic procedure Methods 0.000 description 11
- 201000006549 dyspepsia Diseases 0.000 description 10
- 208000024798 heartburn Diseases 0.000 description 10
- 208000007882 Gastritis Diseases 0.000 description 9
- 208000002193 Pain Diseases 0.000 description 8
- 235000005911 diet Nutrition 0.000 description 8
- 230000002496 gastric effect Effects 0.000 description 8
- 229940126585 therapeutic drug Drugs 0.000 description 8
- 230000037213 diet Effects 0.000 description 7
- 239000008187 granular material Substances 0.000 description 7
- 230000003340 mental effect Effects 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- 208000007107 Stomach Ulcer Diseases 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 238000002386 leaching Methods 0.000 description 6
- 239000000546 pharmaceutical excipient Substances 0.000 description 6
- 206010028813 Nausea Diseases 0.000 description 5
- 239000003795 chemical substances by application Substances 0.000 description 5
- 239000012141 concentrate Substances 0.000 description 5
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- 238000002651 drug therapy Methods 0.000 description 5
- 208000000718 duodenal ulcer Diseases 0.000 description 5
- 230000006870 function Effects 0.000 description 5
- 230000036541 health Effects 0.000 description 5
- 235000012054 meals Nutrition 0.000 description 5
- 230000008693 nausea Effects 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 235000011511 Diospyros Nutrition 0.000 description 4
- 208000004232 Enteritis Diseases 0.000 description 4
- 208000025865 Ulcer Diseases 0.000 description 4
- 239000012153 distilled water Substances 0.000 description 4
- 238000001839 endoscopy Methods 0.000 description 4
- 238000001704 evaporation Methods 0.000 description 4
- 231100000397 ulcer Toxicity 0.000 description 4
- 206010000087 Abdominal pain upper Diseases 0.000 description 3
- 206010010774 Constipation Diseases 0.000 description 3
- 206010012735 Diarrhoea Diseases 0.000 description 3
- 244000236655 Diospyros kaki Species 0.000 description 3
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 3
- 229920002472 Starch Polymers 0.000 description 3
- 206010047700 Vomiting Diseases 0.000 description 3
- 238000009207 exercise therapy Methods 0.000 description 3
- 239000008101 lactose Substances 0.000 description 3
- 238000000034 method Methods 0.000 description 3
- 239000000843 powder Substances 0.000 description 3
- 230000028327 secretion Effects 0.000 description 3
- 239000000243 solution Substances 0.000 description 3
- 239000008107 starch Substances 0.000 description 3
- 235000019698 starch Nutrition 0.000 description 3
- 230000008673 vomiting Effects 0.000 description 3
- 206010000060 Abdominal distension Diseases 0.000 description 2
- 206010000084 Abdominal pain lower Diseases 0.000 description 2
- 206010019233 Headaches Diseases 0.000 description 2
- 206010033557 Palpitations Diseases 0.000 description 2
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 2
- 210000001015 abdomen Anatomy 0.000 description 2
- 206010000059 abdominal discomfort Diseases 0.000 description 2
- 229940069428 antacid Drugs 0.000 description 2
- 239000003159 antacid agent Substances 0.000 description 2
- 230000036528 appetite Effects 0.000 description 2
- 235000019789 appetite Nutrition 0.000 description 2
- 230000004596 appetite loss Effects 0.000 description 2
- 235000021152 breakfast Nutrition 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 208000023652 chronic gastritis Diseases 0.000 description 2
- 230000001079 digestive effect Effects 0.000 description 2
- 208000010643 digestive system disease Diseases 0.000 description 2
- 206010016256 fatigue Diseases 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000030135 gastric motility Effects 0.000 description 2
- 201000005917 gastric ulcer Diseases 0.000 description 2
- 208000018685 gastrointestinal system disease Diseases 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- 231100000869 headache Toxicity 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 206010022437 insomnia Diseases 0.000 description 2
- 210000000936 intestine Anatomy 0.000 description 2
- 230000001788 irregular Effects 0.000 description 2
- 208000019017 loss of appetite Diseases 0.000 description 2
- 235000021266 loss of appetite Nutrition 0.000 description 2
- 238000002483 medication Methods 0.000 description 2
- 230000007721 medicinal effect Effects 0.000 description 2
- 230000001272 neurogenic effect Effects 0.000 description 2
- 239000006187 pill Substances 0.000 description 2
- 238000002360 preparation method Methods 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000003826 tablet Substances 0.000 description 2
- 208000004998 Abdominal Pain Diseases 0.000 description 1
- 229920001817 Agar Polymers 0.000 description 1
- GUBGYTABKSRVRQ-XLOQQCSPSA-N Alpha-Lactose Chemical compound O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-XLOQQCSPSA-N 0.000 description 1
- 206010006326 Breath odour Diseases 0.000 description 1
- 206010009900 Colitis ulcerative Diseases 0.000 description 1
- 229920002261 Corn starch Polymers 0.000 description 1
- 206010011224 Cough Diseases 0.000 description 1
- 241000723267 Diospyros Species 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- 206010015137 Eructation Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 208000010201 Exanthema Diseases 0.000 description 1
- 206010017865 Gastritis erosive Diseases 0.000 description 1
- 206010061459 Gastrointestinal ulcer Diseases 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 206010020601 Hyperchlorhydria Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 206010022998 Irritability Diseases 0.000 description 1
- 206010033372 Pain and discomfort Diseases 0.000 description 1
- 239000000219 Sympatholytic Substances 0.000 description 1
- 201000006704 Ulcerative Colitis Diseases 0.000 description 1
- 230000005856 abnormality Effects 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- XAGFODPZIPBFFR-UHFFFAOYSA-N aluminium Chemical compound [Al] XAGFODPZIPBFFR-UHFFFAOYSA-N 0.000 description 1
- 229910052782 aluminium Inorganic materials 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000002921 anti-spasmodic effect Effects 0.000 description 1
- 230000002180 anti-stress Effects 0.000 description 1
- 230000000767 anti-ulcer Effects 0.000 description 1
- 229940124575 antispasmodic agent Drugs 0.000 description 1
- WQZGKKKJIJFFOK-VFUOTHLCSA-N beta-D-glucose Chemical compound OC[C@H]1O[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-VFUOTHLCSA-N 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 210000003169 central nervous system Anatomy 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 238000013329 compounding Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 239000008120 corn starch Substances 0.000 description 1
- 239000008367 deionised water Substances 0.000 description 1
- 229910021641 deionized water Inorganic materials 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 102000038379 digestive enzymes Human genes 0.000 description 1
- 108091007734 digestive enzymes Proteins 0.000 description 1
- 239000007884 disintegrant Substances 0.000 description 1
- 230000000857 drug effect Effects 0.000 description 1
- 239000003640 drug residue Substances 0.000 description 1
- 230000008482 dysregulation Effects 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 230000008020 evaporation Effects 0.000 description 1
- 201000005884 exanthem Diseases 0.000 description 1
- 239000000706 filtrate Substances 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 210000004051 gastric juice Anatomy 0.000 description 1
- 230000007661 gastrointestinal function Effects 0.000 description 1
- 230000005176 gastrointestinal motility Effects 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000003862 health status Effects 0.000 description 1
- 239000008214 highly purified water Substances 0.000 description 1
- 230000036737 immune function Effects 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- 231100000957 no side effect Toxicity 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 210000005037 parasympathetic nerve Anatomy 0.000 description 1
- 239000000734 parasympathomimetic agent Substances 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001107 psychogenic effect Effects 0.000 description 1
- 206010037844 rash Diseases 0.000 description 1
- 238000011084 recovery Methods 0.000 description 1
- 230000000284 resting effect Effects 0.000 description 1
- 230000002269 spontaneous effect Effects 0.000 description 1
- 230000035882 stress Effects 0.000 description 1
- 230000000948 sympatholitic effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Landscapes
- Medicines Containing Plant Substances (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62192307A JPS6438025A (en) | 1987-07-31 | 1987-07-31 | Remedy for gastrointestinal disease and production thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62192307A JPS6438025A (en) | 1987-07-31 | 1987-07-31 | Remedy for gastrointestinal disease and production thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6438025A JPS6438025A (en) | 1989-02-08 |
| JPH0476972B2 true JPH0476972B2 (enrdf_load_stackoverflow) | 1992-12-07 |
Family
ID=16289095
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62192307A Granted JPS6438025A (en) | 1987-07-31 | 1987-07-31 | Remedy for gastrointestinal disease and production thereof |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6438025A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100418065B1 (ko) * | 2000-08-22 | 2004-02-11 | 주식회사 뉴로넥스 | 히스타민 ｈ2 수용체 길항제 |
-
1987
- 1987-07-31 JP JP62192307A patent/JPS6438025A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6438025A (en) | 1989-02-08 |
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