JPH0470286B2 - - Google Patents
Info
- Publication number
- JPH0470286B2 JPH0470286B2 JP61170551A JP17055186A JPH0470286B2 JP H0470286 B2 JPH0470286 B2 JP H0470286B2 JP 61170551 A JP61170551 A JP 61170551A JP 17055186 A JP17055186 A JP 17055186A JP H0470286 B2 JPH0470286 B2 JP H0470286B2
- Authority
- JP
- Japan
- Prior art keywords
- baicalein
- baicalin
- scutellariae
- extract
- scutellaria
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- FXNFHKRTJBSTCS-UHFFFAOYSA-N Baicalein Natural products C=1C(=O)C=2C(O)=C(O)C(O)=CC=2OC=1C1=CC=CC=C1 FXNFHKRTJBSTCS-UHFFFAOYSA-N 0.000 claims description 46
- UDFLTIRFTXWNJO-UHFFFAOYSA-N baicalein Chemical compound O1C2=CC(=O)C(O)=C(O)C2=C(O)C=C1C1=CC=CC=C1 UDFLTIRFTXWNJO-UHFFFAOYSA-N 0.000 claims description 46
- 229940015301 baicalein Drugs 0.000 claims description 46
- 239000000284 extract Substances 0.000 claims description 23
- 241000207929 Scutellaria Species 0.000 claims description 15
- 238000000034 method Methods 0.000 claims description 15
- 239000000843 powder Substances 0.000 claims description 12
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 9
- 238000010438 heat treatment Methods 0.000 claims description 8
- IPQKDIRUZHOIOM-UHFFFAOYSA-N Oroxin A Natural products OC1C(O)C(O)C(CO)OC1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC=CC=1)O2 IPQKDIRUZHOIOM-UHFFFAOYSA-N 0.000 description 36
- IKIIZLYTISPENI-ZFORQUDYSA-N baicalin Chemical compound O1[C@H](C(O)=O)[C@@H](O)[C@H](O)[C@@H](O)[C@@H]1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC=CC=1)O2 IKIIZLYTISPENI-ZFORQUDYSA-N 0.000 description 36
- 229960003321 baicalin Drugs 0.000 description 36
- AQHDANHUMGXSJZ-UHFFFAOYSA-N baicalin Natural products OC1C(O)C(C(O)CO)OC1OC(C(=C1O)O)=CC2=C1C(=O)C=C(C=1C=CC=CC=1)O2 AQHDANHUMGXSJZ-UHFFFAOYSA-N 0.000 description 36
- 238000000605 extraction Methods 0.000 description 18
- 238000006243 chemical reaction Methods 0.000 description 11
- 239000000243 solution Substances 0.000 description 10
- 238000007654 immersion Methods 0.000 description 9
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 8
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 description 6
- 239000002537 cosmetic Substances 0.000 description 5
- 239000003814 drug Substances 0.000 description 5
- 101000874322 Scutellaria baicalensis Baicalin-beta-D-glucuronidase Proteins 0.000 description 4
- 238000011160 research Methods 0.000 description 4
- 235000000346 sugar Nutrition 0.000 description 4
- 238000007796 conventional method Methods 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- TWCMVXMQHSVIOJ-UHFFFAOYSA-N Aglycone of yadanzioside D Natural products COC(=O)C12OCC34C(CC5C(=CC(O)C(O)C5(C)C3C(O)C1O)C)OC(=O)C(OC(=O)C)C24 TWCMVXMQHSVIOJ-UHFFFAOYSA-N 0.000 description 2
- PLMKQQMDOMTZGG-UHFFFAOYSA-N Astrantiagenin E-methylester Natural products CC12CCC(O)C(C)(CO)C1CCC1(C)C2CC=C2C3CC(C)(C)CCC3(C(=O)OC)CCC21C PLMKQQMDOMTZGG-UHFFFAOYSA-N 0.000 description 2
- 201000004624 Dermatitis Diseases 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 238000004128 high performance liquid chromatography Methods 0.000 description 2
- PFOARMALXZGCHY-UHFFFAOYSA-N homoegonol Natural products C1=C(OC)C(OC)=CC=C1C1=CC2=CC(CCCO)=CC(OC)=C2O1 PFOARMALXZGCHY-UHFFFAOYSA-N 0.000 description 2
- 239000004615 ingredient Substances 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 238000012827 research and development Methods 0.000 description 2
- 230000004913 activation Effects 0.000 description 1
- 239000004480 active ingredient Substances 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000007073 chemical hydrolysis Effects 0.000 description 1
- 238000003776 cleavage reaction Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 238000001035 drying Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000008177 pharmaceutical agent Substances 0.000 description 1
- 239000002831 pharmacologic agent Substances 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 238000002203 pretreatment Methods 0.000 description 1
- 238000012545 processing Methods 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 239000002994 raw material Substances 0.000 description 1
- 230000009257 reactivity Effects 0.000 description 1
- 230000007017 scission Effects 0.000 description 1
- 239000007858 starting material Substances 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
- A61K8/9728—Fungi, e.g. yeasts
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Botany (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61170551A JPS6327435A (ja) | 1986-07-18 | 1986-07-18 | バイカレイン高含有エキスの抽出法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP61170551A JPS6327435A (ja) | 1986-07-18 | 1986-07-18 | バイカレイン高含有エキスの抽出法 |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS6327435A JPS6327435A (ja) | 1988-02-05 |
JPH0470286B2 true JPH0470286B2 (zh) | 1992-11-10 |
Family
ID=15906968
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP61170551A Granted JPS6327435A (ja) | 1986-07-18 | 1986-07-18 | バイカレイン高含有エキスの抽出法 |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS6327435A (zh) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103961661A (zh) * | 2014-04-10 | 2014-08-06 | 李红 | 一种用于治疗牛皮癣的外用液体药物及制备方法 |
CN104530161A (zh) * | 2014-12-03 | 2015-04-22 | 安徽海神寿春药业有限公司 | 一种黄芩提取物的生产工艺 |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0236125A (ja) * | 1988-07-26 | 1990-02-06 | Ichimaru Pharcos Co Ltd | テストステロン5α−リダクターゼ阻害剤 |
CN1242807C (zh) * | 2000-11-08 | 2006-02-22 | 天津市延龄营养保健品有限公司 | 一种抗皮肤过敏的药物组合物及其制法和用途 |
US7972632B2 (en) | 2003-02-28 | 2011-07-05 | Unigen Pharmaceuticals, Inc. | Identification of Free-B-Ring flavonoids as potent COX-2 inhibitors |
US7108868B2 (en) | 2002-03-22 | 2006-09-19 | Unigen Pharmaceuticals, Inc. | Isolation of a dual cox-2 and 5-lipoxygenase inhibitor from acacia |
CA2484192C (en) | 2002-04-30 | 2012-10-02 | Unigen Pharmaceuticals, Inc. | Formulation of a mixture of free-b-ring flavonoids and flavans as a therapeutic agent |
US8945518B2 (en) | 2002-04-30 | 2015-02-03 | Unigen, Inc. | Formulation of dual eicosanoid system and cytokine system inhibitors for use in the prevention and treatment of oral diseases and conditions |
BRPI0409179A (pt) | 2003-04-04 | 2006-05-02 | Unigen Pharmaceuticals Inc | formulação de inibidores duplos de ciclooxigenase (cox) e lipoxigenase (lox) para cuidados com a pele de mamìferos |
WO2005045051A1 (en) * | 2003-11-05 | 2005-05-19 | Novozymes A/S | Baicalin de-glycosylation |
KR100761248B1 (ko) | 2006-10-12 | 2007-10-04 | 주식회사 유니젠 | 대나무 및 황금 추출물을 유효성분으로 함유하는 아토피성피부염 치료를 위한 조성물 |
WO2010040058A1 (en) * | 2008-10-02 | 2010-04-08 | George Zabrecky | Methods and formulations for treating chronic liver disease |
CN104991029A (zh) * | 2015-05-07 | 2015-10-21 | 北京东方运嘉科技发展有限公司 | 一种小儿止咳药物的质量检测方法 |
-
1986
- 1986-07-18 JP JP61170551A patent/JPS6327435A/ja active Granted
Non-Patent Citations (1)
Title |
---|
ACTA PHYTOCHIMICA=1935 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN103961661A (zh) * | 2014-04-10 | 2014-08-06 | 李红 | 一种用于治疗牛皮癣的外用液体药物及制备方法 |
CN104530161A (zh) * | 2014-12-03 | 2015-04-22 | 安徽海神寿春药业有限公司 | 一种黄芩提取物的生产工艺 |
Also Published As
Publication number | Publication date |
---|---|
JPS6327435A (ja) | 1988-02-05 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
JPH0470286B2 (zh) | ||
KR100377546B1 (ko) | 효소적 방법에 의한 진세노사이드 컴파운드 케이의 제조방법 | |
TW200416037A (en) | Process for producing hydrophobic glycyrrhiza extract with high qualities | |
US20190022159A1 (en) | Novel method for preparing purified extracts of harpagophytum procumbens | |
CN100462091C (zh) | 中药材炮制方法 | |
CN102078341B (zh) | 高纯度银杏黄酮及组合物 | |
CN114907184A (zh) | 一种高纯度丹参素钠的提取工艺 | |
JP2004518751A (ja) | Liangtoujian抽出物の製造方法、その抽出物を含有する医薬組成物及びその用途 | |
CN111205302B (zh) | 一种大果木姜子果实提取物、提取方法及制备方法和应用 | |
JP2727096B2 (ja) | 抗皮膚糸状菌剤 | |
Sah et al. | Hypoglycemic activity of aqueous extract of Urtica parviflora roxb. in normoglycemic rats | |
Lekar et al. | Study of an acid-free technique for the preparation of glycyrrhetinic acid from ammonium glycyrrhizinate in subcritical water | |
CN110922444B (zh) | 具有抗炎活性的人参二醇型三萜皂苷 | |
Gujral et al. | Antiarthritic activity of Glycyrrhiza glabra Linn | |
CN1748725A (zh) | 木鳖子含三萜皂甙成分提取物的制备方法 | |
JPS6236330A (ja) | センブリ抽出エキス及びその製法 | |
JP4308714B2 (ja) | 天然物由来グリセロ糖脂質の製造方法 | |
KR890001237B1 (ko) | 자근 색소의 추출방법 | |
JP2631686B2 (ja) | 新規ステロイドサポニンおよびその製造法ならびにこれらの誘導体の新規用途 | |
CN105481935B (zh) | 常春藤皂苷元衍生物及其在制备防治老年痴呆的药物中的应用 | |
KR19980066516A (ko) | 효소처리법에 의한 식물에 함유된 사포닌을 포함한 유효성분을 추출하는 방법 | |
JPS5980699A (ja) | ギノサポニン類 | |
JPH0840912A (ja) | 糖吸収抑制剤 | |
CN108558645A (zh) | 从栀子中提取藏红花素的方法 | |
KR950005739B1 (ko) | 포공영으로부터 항균활성이 높은 엑기스의 추출, 정제방법 |