JPH04506672A - 金属錯体 - Google Patents

金属錯体

Info

Publication number
JPH04506672A
JPH04506672A JP3506948A JP50694891A JPH04506672A JP H04506672 A JPH04506672 A JP H04506672A JP 3506948 A JP3506948 A JP 3506948A JP 50694891 A JP50694891 A JP 50694891A JP H04506672 A JPH04506672 A JP H04506672A
Authority
JP
Japan
Prior art keywords
hydroxy
pyrone
substituted
methyl
groups
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP3506948A
Other languages
English (en)
Japanese (ja)
Inventor
ハイダー，ロバート・チャールズ
ヒューンズ，アーネスト・レインハード
ポーター，ジョン・ブルック
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of JPH04506672A publication Critical patent/JPH04506672A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
    • C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
    • C07D309/40—Oxygen atoms attached in positions 3 and 4, e.g. maltol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pyridine Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
JP3506948A 1990-03-23 1991-03-22 金属錯体 Pending JPH04506672A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9006522.8 1990-03-23
GB909006522A GB9006522D0 (en) 1990-03-23 1990-03-23 Metal complexes

Publications (1)

Publication Number Publication Date
JPH04506672A true JPH04506672A (ja) 1992-11-19

Family

ID=10673114

Family Applications (1)

Application Number Title Priority Date Filing Date
JP3506948A Pending JPH04506672A (ja) 1990-03-23 1991-03-22 金属錯体

Country Status (5)

Country Link
EP (1) EP0473764A1 (de)
JP (1) JPH04506672A (de)
CA (1) CA2058288A1 (de)
GB (2) GB9006522D0 (de)
WO (1) WO1991014664A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5574027A (en) * 1989-11-22 1996-11-12 Bernstein; Lawrence R. Pharmaceutical compositions of gallium complexes of 3-hydroxy-4-pyrones
US6004951A (en) * 1989-11-22 1999-12-21 Bernstein; Lawrence Richard Administration of gallium complexes of 3-hydroxy-4-pyrones to provide physiologically active gallium levels in a mammalian individual
US5258376A (en) * 1989-11-22 1993-11-02 Bernstein Lawrence R Pharmaceutical compositions of gallium complexes of 3-hydroxy-4-pyrones
DK0612246T3 (da) * 1991-11-12 2000-12-27 Lawrence Richard Bernstein Farmaceutiske sammensætninger af galliumkomplekser med 3-hydroxy-4-pyroner
US5336482A (en) * 1991-12-05 1994-08-09 The Du Pont Merck Pharmaceutical Company Technetium-99m complexes with N-substituted 3-hydroxy-4-pyridinones
US5298525A (en) * 1992-11-23 1994-03-29 University Technologies International, Inc. Diabetes prevention and treatment
US6448273B1 (en) 1997-05-29 2002-09-10 Btg International Limited Orally active iron (III) chelators
GB9711093D0 (en) 1997-05-29 1997-07-23 British Tech Group Novel orally active iron (III) chelators
EP2319544A1 (de) 2004-01-16 2011-05-11 Carnegie Mellon University Zellulare Markierung zur kernmagnetischen Resonanz
CA2649333C (en) 2006-04-14 2016-10-04 Carnegie Mellon University Cellular labeling and quantification for nuclear magnetic resonance techniques
AU2008275578B2 (en) 2007-07-10 2014-04-10 Carnegie Mellon University Compositions and methods for producing cellular labels for nuclear magnetic resonance techniques

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3468915A (en) * 1966-04-18 1969-09-23 Pfizer & Co C Novel 2-substituted-6-methylpyromeconic acids
DE2304381C3 (de) * 1973-01-30 1979-06-21 Byk-Mallinckrodt, Chemische Produkte Gmbh, 6057 Dietzenbach Hoch 113m Indium-acetylacetonat enthaltendes Mittel für die szintigraphische Funktionsdiagnostik der Leber auf dessen Herstellung
FR2390408A1 (fr) * 1977-05-11 1978-12-08 Philips France Procede de marquage par un isotope radioactif d'un sel hydrosoluble d'oxine, ou de ses derives halogenes ou sulfones, produits ainsi marques, procede de marquage des elements figures du sang, et medicaments ainsi obtenus
GB2117766B (en) * 1982-03-24 1985-08-29 Nat Res Dev Pharmaceutical compositions
EP0107458B1 (de) * 1982-10-22 1987-07-29 National Research Development Corporation Pharmazeutische Zusammensetzungen
GB8308055D0 (en) * 1983-03-24 1983-05-05 Hider R C Pharmaceutical compositions
AU580958B2 (en) * 1983-07-07 1989-02-09 Mallinckrodt, Inc. Sterile radioactive indium-containing aqueous solution

Also Published As

Publication number Publication date
GB9006522D0 (en) 1990-05-23
GB9106137D0 (en) 1991-05-08
EP0473764A1 (de) 1992-03-11
GB2242191A (en) 1991-09-25
WO1991014664A1 (en) 1991-10-03
GB2242191B (en) 1993-12-08
CA2058288A1 (en) 1991-09-24

Similar Documents

Publication Publication Date Title
EP0123504B1 (de) Komplexe von Technetium-99m mit Alkylenaminoximen
US5480990A (en) Bicyclopolyazamacrocyclocarboxylic acid complexes for use as contrast agents
US5342604A (en) Complexes possessing ortho ligating functionality
US4452774A (en) Isonitrile radionuclide complexes for labelling and imaging agents
US5714631A (en) Conjugates possessing ortho ligating functionality
KR910009202B1 (ko) 포르피린 유도체의 제조방법
US5417960A (en) Nitrogen-containing cyclic ligands, metallic complexes formed by these ligands, diagnostic compositions containing these complexes and process for the preparation of the ligands
JPH04506672A (ja) 金属錯体
KR101315152B1 (ko) 신규 유기화합물 및 상기 화합물을 이용한 방사성 할로겐표식 유기화합물의 제조 방법
JPH03502575A (ja) 希土類クリプテート及びその製造方法とその合成中間体とその蛍光トレーサーとしての利用方法
WO2013042668A1 (ja) 放射性フッ素標識化合物
CN112625065A (zh) 锝-99m标记含肼基尼古酰胺基的FAPI衍生物及制备方法和应用
IE980697A1 (en) Chelants possessing ortho ligating functionality and complexes thereof
JPS6296460A (ja) 診断用放射性化合物、その製法及びキツト
CN110183493B (zh) 一种99m锝标记配合物及其在诊断非小细胞肺癌中的应用
KR20110045023A (ko) 아밀로이드 침착물의 영상화에 유용한 화합물의 전구체로서 적합한 신규한 벤조푸란
HUT67602A (en) Process for producing bicyclo-polyaza-macrocyclo-carboxylic acid complexes, their conjugates and contrast materials containing them
US5645818A (en) Diagnostic compositions comprising a complex formed by a nitrogenous macrocyclic ligand with metal ions
JPH11217385A (ja) 含フッ素ポルフィリン錯体およびそれを含有する造影剤
CN103497217A (zh) 与Aβ斑块具有高亲和力的2-芳基苯并噻唑类化合物、其制备方法及应用
Kanazawa et al. 19F NMR of 2‐deoxy‐2‐fluoro‐D‐glucose for tumor diagnosis in mice. An NDP‐bound hexose analog as a new NMR target for imaging
JPH02304068A (ja) 置換された１，４，７，１０‐テトラアザシクロトリデカン
Martin et al. Synthesis and Characterization of 2-Iodo-4-[5′-(4'″-Methylpiperazin-1'″-yl)-2′, 5′-bi-1h-Benzimidazol-2′-Yl] Phenol (iodoHoechst 33258) and 2, 5-Disubstituted Benzimidazole Model Compounds
JP3190615B2 (ja) 放射性医薬品の製造方法及びキット
JP2013506633A (ja) ヒドロキシル化コントラスト増強剤及びその中間体