JPH0448775B2 - - Google Patents
Info
- Publication number
- JPH0448775B2 JPH0448775B2 JP55086675A JP8667580A JPH0448775B2 JP H0448775 B2 JPH0448775 B2 JP H0448775B2 JP 55086675 A JP55086675 A JP 55086675A JP 8667580 A JP8667580 A JP 8667580A JP H0448775 B2 JPH0448775 B2 JP H0448775B2
- Authority
- JP
- Japan
- Prior art keywords
- compound
- parasites
- animal
- dimethylformamide
- warm
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 241001465754 Metazoa Species 0.000 claims description 29
- 150000001875 compounds Chemical class 0.000 claims description 27
- 238000000034 method Methods 0.000 claims description 25
- ZMXDDKWLCZADIW-UHFFFAOYSA-N N,N-Dimethylformamide Chemical compound CN(C)C=O ZMXDDKWLCZADIW-UHFFFAOYSA-N 0.000 claims description 24
- 239000000203 mixture Substances 0.000 claims description 16
- 244000045947 parasite Species 0.000 claims description 12
- 230000037396 body weight Effects 0.000 claims description 7
- IAZDPXIOMUYVGZ-UHFFFAOYSA-N Dimethylsulphoxide Chemical compound CS(C)=O IAZDPXIOMUYVGZ-UHFFFAOYSA-N 0.000 claims description 4
- -1 α-cyano-3-phenoxybenzyl Chemical group 0.000 claims description 4
- CYCYDSJDZNVSPP-OVEKKEMJSA-N (1r,3s)-3-(1,2-dibromo-2,2-dichloroethyl)-2,2-dimethylcyclopropane-1-carboxylic acid Chemical compound CC1(C)[C@@H](C(Br)C(Cl)(Cl)Br)[C@H]1C(O)=O CYCYDSJDZNVSPP-OVEKKEMJSA-N 0.000 claims description 2
- WKBOTKDWSSQWDR-UHFFFAOYSA-N Bromine atom Chemical group [Br] WKBOTKDWSSQWDR-UHFFFAOYSA-N 0.000 claims description 2
- FXHOOIRPVKKKFG-UHFFFAOYSA-N N,N-Dimethylacetamide Chemical compound CN(C)C(C)=O FXHOOIRPVKKKFG-UHFFFAOYSA-N 0.000 claims description 2
- 239000004480 active ingredient Substances 0.000 claims description 2
- 229910052801 chlorine Inorganic materials 0.000 claims description 2
- 239000000460 chlorine Substances 0.000 claims description 2
- 125000001309 chloro group Chemical group Cl* 0.000 claims description 2
- 235000015112 vegetable and seed oil Nutrition 0.000 claims description 2
- 239000008158 vegetable oil Substances 0.000 claims description 2
- YMGUBTXCNDTFJI-UHFFFAOYSA-N cyclopropanecarboxylic acid Chemical compound OC(=O)C1CC1 YMGUBTXCNDTFJI-UHFFFAOYSA-N 0.000 claims 1
- 239000000126 substance Substances 0.000 claims 1
- 229940126062 Compound A Drugs 0.000 description 15
- NLDMNSXOCDLTTB-UHFFFAOYSA-N Heterophylliin A Natural products O1C2COC(=O)C3=CC(O)=C(O)C(O)=C3C3=C(O)C(O)=C(O)C=C3C(=O)OC2C(OC(=O)C=2C=C(O)C(O)=C(O)C=2)C(O)C1OC(=O)C1=CC(O)=C(O)C(O)=C1 NLDMNSXOCDLTTB-UHFFFAOYSA-N 0.000 description 15
- 241000238876 Acari Species 0.000 description 13
- 230000000694 effects Effects 0.000 description 8
- 238000011282 treatment Methods 0.000 description 7
- 238000012360 testing method Methods 0.000 description 5
- 241000403354 Microplus Species 0.000 description 4
- 239000003981 vehicle Substances 0.000 description 4
- 241000283690 Bos taurus Species 0.000 description 3
- 244000309464 bull Species 0.000 description 3
- 239000004006 olive oil Substances 0.000 description 3
- 235000008390 olive oil Nutrition 0.000 description 3
- 241000864202 Rhipicephalus evertsi Species 0.000 description 2
- 241000238680 Rhipicephalus microplus Species 0.000 description 2
- 239000013543 active substance Substances 0.000 description 2
- 239000003995 emulsifying agent Substances 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 238000007911 parenteral administration Methods 0.000 description 2
- 239000004540 pour-on Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 230000001839 systemic circulation Effects 0.000 description 2
- VSBCUTLTLUSECJ-OVEKKEMJSA-N (1R)-cis-2,2-dimethyl-3-(1,2,2,2-tetrabromoethyl)cyclopropanecarboxylic acid Chemical compound CC1(C)[C@@H](C(Br)C(Br)(Br)Br)[C@H]1C(O)=O VSBCUTLTLUSECJ-OVEKKEMJSA-N 0.000 description 1
- 206010063409 Acarodermatitis Diseases 0.000 description 1
- 241000238679 Amblyomma Species 0.000 description 1
- 244000272765 Elaeocarpus serratus Species 0.000 description 1
- 208000018522 Gastrointestinal disease Diseases 0.000 description 1
- 241001480803 Hyalomma Species 0.000 description 1
- 235000019483 Peanut oil Nutrition 0.000 description 1
- 241001494479 Pecora Species 0.000 description 1
- 241001481704 Rhipicephalus appendiculatus Species 0.000 description 1
- 241001251773 Rhipicephalus simus Species 0.000 description 1
- 241000447727 Scabies Species 0.000 description 1
- 241000282887 Suidae Species 0.000 description 1
- 230000000895 acaricidal effect Effects 0.000 description 1
- 244000309466 calf Species 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 150000002170 ethers Chemical class 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 230000000855 fungicidal effect Effects 0.000 description 1
- 244000144980 herd Species 0.000 description 1
- 230000000749 insecticidal effect Effects 0.000 description 1
- 244000144972 livestock Species 0.000 description 1
- 239000002207 metabolite Substances 0.000 description 1
- 230000001069 nematicidal effect Effects 0.000 description 1
- 239000003921 oil Substances 0.000 description 1
- 235000019198 oils Nutrition 0.000 description 1
- 239000003960 organic solvent Substances 0.000 description 1
- 239000000312 peanut oil Substances 0.000 description 1
- 230000000361 pesticidal effect Effects 0.000 description 1
- 229920000151 polyglycol Polymers 0.000 description 1
- 239000010695 polyglycol Substances 0.000 description 1
- 208000005687 scabies Diseases 0.000 description 1
- 238000010561 standard procedure Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 238000011200 topical administration Methods 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N53/00—Biocides, pest repellants or attractants, or plant growth regulators containing cyclopropane carboxylic acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/215—Esters, e.g. nitroglycerine, selenocyanates of carboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/34—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plant Pathology (AREA)
- Dermatology (AREA)
- Emergency Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dentistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7916892A FR2484256B1 (fr) | 1979-06-29 | 1979-06-29 | Procede de lutte contre les parasites des animaux a sang chaud |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS568316A JPS568316A (en) | 1981-01-28 |
| JPH0448775B2 true JPH0448775B2 (de) | 1992-08-07 |
Family
ID=9227301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP8667580A Granted JPS568316A (en) | 1979-06-29 | 1980-06-27 | Novel composition for exterminating warmmblooded animal parasite |
Country Status (9)
| Country | Link |
|---|---|
| JP (1) | JPS568316A (de) |
| AU (1) | AU541208B2 (de) |
| CH (1) | CH645023A5 (de) |
| DE (1) | DE3024323A1 (de) |
| FR (1) | FR2484256B1 (de) |
| GB (1) | GB2052988B (de) |
| NZ (1) | NZ194171A (de) |
| OA (1) | OA06524A (de) |
| ZA (1) | ZA803621B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2471187A1 (fr) * | 1979-12-10 | 1981-06-19 | Roussel Uclaf | Nouvelles compositions destinees a la lutte contre les parasites des animaux a sang chaud |
| HU182802B (en) * | 1980-02-26 | 1984-03-28 | Biogal Gyogyszergyar | Fotostabil delousing (insecticide) composition containing synthetic piretroides |
| DE3208334A1 (de) * | 1982-03-09 | 1983-09-15 | Bayer Ag, 5090 Leverkusen | Pestizide pour-on-formulierungen |
| FR2523444B1 (fr) * | 1982-03-16 | 1987-07-24 | Wellcome Australia | Formule antiparasitaire pour mammiferes appliquee localement, contenant une association d'un pyrethroide et d'un thiazole |
| FR2555449B1 (fr) * | 1983-11-25 | 1986-11-14 | Applipharm Ctre Rech Applic P | Composition a base de pyrethroides pour le traitement local des parasitoses cutanees |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5340744A (en) * | 1976-09-21 | 1978-04-13 | Roussel Uclaf | Novel cyclopropane carboxylate containing polyhalogen substituent and agricultural chemical composition |
| JPS5391127A (en) * | 1976-12-24 | 1978-08-10 | Wellcome Found | Animal medicine for exterminating harmful organism |
| JPS53101340A (en) * | 1977-02-11 | 1978-09-04 | Ciba Geigy Ag | Cyclopropanecarboxylate * its preparation and preventing agent for harmful organism containing said compound |
| JPS53104733A (en) * | 1976-12-24 | 1978-09-12 | Wellcome Found | Mite protecting composition |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL180633C (nl) * | 1973-06-22 | 1900-01-01 | Bayer Ag | Werkwijze ter bereiding van een anthelmintisch werkzaam veterinair opgiet-preparaat. |
| FR2398041A2 (fr) * | 1977-07-19 | 1979-02-16 | Roussel Uclaf | Esters d'acides cyclopropane carboxylique comportant un substituant polyhalogene, procede de preparation et leur application comme insecticides, acaricides, nematicides et comme medicaments veterinaires |
| FR2364884A1 (fr) * | 1976-09-21 | 1978-04-14 | Roussel Uclaf | Nouveaux esters d'acides cyclopropane, carboxyliques comportant un substituant polyhalogene, procedes de preparation et compositions insecticides les renfermant |
| FR2419932A2 (fr) * | 1978-03-17 | 1979-10-12 | Roussel Uclaf | Nouveaux esters d'acides cyclopropane carboxyliques comportant un substituant polyhalogene, procede de preparation et compositions insecticides les renfermant |
| DE2709264C3 (de) * | 1977-03-03 | 1982-01-21 | Bayer Ag, 5090 Leverkusen | Substituierte Phenoxybenzyloxycarbonylderivate, Verfahren zu ihrer Herstellung und ihre Verwendung als Insektizide und Akarizide sowie neue Zwischenprodukte |
| DE2730515A1 (de) * | 1977-07-06 | 1979-01-18 | Bayer Ag | Substituierte phenoxybenzyloxycarbonylderivate, verfahren zu ihrer herstellung und ihre verwendung als insektizide und akarizide |
-
1979
- 1979-06-29 FR FR7916892A patent/FR2484256B1/fr not_active Expired
-
1980
- 1980-04-29 OA OA57100A patent/OA06524A/xx unknown
- 1980-06-17 ZA ZA00803621A patent/ZA803621B/xx unknown
- 1980-06-27 NZ NZ194171A patent/NZ194171A/en unknown
- 1980-06-27 GB GB8021250A patent/GB2052988B/en not_active Expired
- 1980-06-27 JP JP8667580A patent/JPS568316A/ja active Granted
- 1980-06-27 CH CH498180A patent/CH645023A5/fr not_active IP Right Cessation
- 1980-06-27 DE DE19803024323 patent/DE3024323A1/de active Granted
- 1980-06-27 AU AU59736/80A patent/AU541208B2/en not_active Expired
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5340744A (en) * | 1976-09-21 | 1978-04-13 | Roussel Uclaf | Novel cyclopropane carboxylate containing polyhalogen substituent and agricultural chemical composition |
| JPS5340743A (en) * | 1976-09-21 | 1978-04-13 | Roussel Uclaf | Novel cyclopropane carboxylate ester containing polyhalogen substituent process for preparing same and agriclutural chemical composition |
| JPS5391127A (en) * | 1976-12-24 | 1978-08-10 | Wellcome Found | Animal medicine for exterminating harmful organism |
| JPS53104733A (en) * | 1976-12-24 | 1978-09-12 | Wellcome Found | Mite protecting composition |
| JPS53101340A (en) * | 1977-02-11 | 1978-09-04 | Ciba Geigy Ag | Cyclopropanecarboxylate * its preparation and preventing agent for harmful organism containing said compound |
Also Published As
| Publication number | Publication date |
|---|---|
| AU541208B2 (en) | 1984-12-20 |
| CH645023A5 (fr) | 1984-09-14 |
| JPS568316A (en) | 1981-01-28 |
| OA06524A (fr) | 1981-07-31 |
| FR2484256B1 (fr) | 1986-10-24 |
| GB2052988B (en) | 1983-04-07 |
| NZ194171A (en) | 1985-01-31 |
| GB2052988A (en) | 1981-02-04 |
| FR2484256A1 (fr) | 1981-12-18 |
| AU5973680A (en) | 1981-01-08 |
| ZA803621B (en) | 1982-01-27 |
| DE3024323C2 (de) | 1991-04-25 |
| DE3024323A1 (de) | 1981-01-22 |
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