JPH0441000B2 - - Google Patents
Info
- Publication number
- JPH0441000B2 JPH0441000B2 JP60229763A JP22976385A JPH0441000B2 JP H0441000 B2 JPH0441000 B2 JP H0441000B2 JP 60229763 A JP60229763 A JP 60229763A JP 22976385 A JP22976385 A JP 22976385A JP H0441000 B2 JPH0441000 B2 JP H0441000B2
- Authority
- JP
- Japan
- Prior art keywords
- prothrombin
- abnormal
- patients
- antigen
- vitamin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
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- 108010094028 Prothrombin Proteins 0.000 claims abstract description 218
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- 235000019168 vitamin K Nutrition 0.000 description 17
- 239000011712 vitamin K Substances 0.000 description 17
- 150000003721 vitamin K derivatives Chemical class 0.000 description 17
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Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/86—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood coagulating time or factors, or their receptors
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3038—Kidney, bladder
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/36—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against blood coagulation factors
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/81—Packaged device or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/807—Apparatus included in process claim, e.g. physical support structures
- Y10S436/808—Automated or kit
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/811—Test for named disease, body condition or organ function
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/815—Test for named compound or class of compounds
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Hematology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Genetics & Genomics (AREA)
- Cell Biology (AREA)
- Biomedical Technology (AREA)
- Analytical Chemistry (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Biotechnology (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Measuring And Recording Apparatus For Diagnosis (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Description
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Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US661187 | 1984-10-15 | ||
US06/661,187 US4769320A (en) | 1982-07-27 | 1984-10-15 | Immunoassay means and methods useful in human native prothrombin and human abnormal prothorombin determinations |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS61117457A JPS61117457A (ja) | 1986-06-04 |
JPH0441000B2 true JPH0441000B2 (ja) | 1992-07-06 |
Family
ID=24652562
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP60229763A Granted JPS61117457A (ja) | 1984-10-15 | 1985-10-15 | ã¢ãã¯ãâãã«æäœ |
Country Status (5)
Country | Link |
---|---|
US (1) | US4769320A (ja) |
EP (1) | EP0182495B1 (ja) |
JP (1) | JPS61117457A (ja) |
AT (1) | ATE52141T1 (ja) |
DE (1) | DE3577233D1 (ja) |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11359009B2 (en) | 2015-12-25 | 2022-06-14 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
US11608374B2 (en) | 2017-01-30 | 2023-03-21 | Chugai Seiyaku Kabushiki Kaisha | Anti-sclerostin antibodies and methods of use |
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6258938B1 (en) * | 1983-10-28 | 2001-07-10 | Ne Medical Center Hospital, Inc. | Method for the purification and isolation of blood clotting proteins using conformation specific antibodies |
DE3727610A1 (de) * | 1987-08-19 | 1989-03-02 | Behringwerke Ag | Synthetische peptide, gegen diese gerichtete antikoerper und deren verwendung |
US5147779A (en) * | 1988-06-01 | 1992-09-15 | Miles Inc. | Method for evaluating immunogenicity |
US5217870A (en) * | 1989-04-28 | 1993-06-08 | Biogen, Inc. | Monoclonal antibodies against CDX |
US5272263A (en) * | 1989-04-28 | 1993-12-21 | Biogen, Inc. | DNA sequences encoding vascular cell adhesion molecules (VCAMS) |
US5532136A (en) * | 1993-06-22 | 1996-07-02 | Bionebraska, Inc. | Monoclonal antibody assay and kit for detecting metal cations in body fluids |
US20020040008A1 (en) * | 1995-01-24 | 2002-04-04 | Wagner Denisa D. | Method for treating and preventing atherosclerosis |
WO1998005055A1 (fr) * | 1996-07-27 | 1998-02-05 | Moriyama Sangyo Kabushiki Kaisha | Dispositif emetteur de lumiere, dispositif de douille et dispositif d'eclairage |
US5935802A (en) * | 1998-08-10 | 1999-08-10 | Evanston Northwestern Healthcare Research Institute | Method of assaying a blood sample for prothrombin |
CA2378711A1 (en) * | 1999-08-14 | 2001-02-22 | November Aktiengesellschaft Gesellschaft Fur Molekulare Medizin | Method for indirectly determining the blood-clotting status |
DE19941447C2 (de) * | 1999-08-14 | 2002-06-27 | November Ag Molekulare Medizin | Verfahren zur indirekten Bestimmung des Blutgerinnungsstatus |
AU2003296086A1 (en) * | 2002-12-26 | 2004-07-22 | Nitto Boseki Co., Ltd. | Immunoassay method and kit to be used therein |
LT2708559T (lt) | 2008-04-11 | 2018-06-11 | Chugai Seiyaku Kabushiki Kaisha | AntigenÄ suriÅ¡anti molekulÄ, galinti pakartotinai prisijungti prie dviejų ar daugiau antigeno molekulių |
TWI440469B (zh) | 2008-09-26 | 2014-06-11 | Chugai Pharmaceutical Co Ltd | Improved antibody molecules |
US8283162B2 (en) * | 2009-03-10 | 2012-10-09 | Abbott Laboratories | Antibodies relating to PIVKAII and uses thereof |
EP2647706B1 (en) * | 2010-11-30 | 2023-05-17 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule capable of binding to plurality of antigen molecules repeatedly |
MX352889B (es) | 2011-02-25 | 2017-12-13 | Chugai Pharmaceutical Co Ltd | Anticuerpo de fc especifico para fcyriib. |
TW201817745A (zh) | 2011-09-30 | 2018-05-16 | æ¥åäžå€è£œè¥è¡ä»œæéå ¬åž | å ·æä¿é²æåæž é€ä¹ïŒŠïœïŒ²ïœçµååçæ²»çæ§æåçµååå |
US20150050269A1 (en) | 2011-09-30 | 2015-02-19 | Chugai Seiyaku Kabushiki Kaisha | Antigen-binding molecule promoting disappearance of antigens having plurality of biological activities |
SG11201700841QA (en) | 2014-12-19 | 2017-03-30 | Chugai Pharmaceutical Co Ltd | Anti-myostatin antibodies, polypeptides containing variant fc regions, and methods of use |
MY183415A (en) | 2014-12-19 | 2021-02-18 | Chugai Pharmaceutical Co Ltd | Anti-c5 antibodies and methods of use |
KR102605798B1 (ko) | 2015-02-05 | 2023-11-23 | ì¶ê°ìŽ ìžìŽìŒì¿ ê°ë¶ìí€ê°ìŽì€ | ìŽìš ëë ìì¡Žì íì ê²°í© ëë©ìžì í¬íšíë í첎, Fc ìì ê°ë³ì²Ž, IL-8ì ê²°í©íë í첎, ë° ê·žë€ì ì¬ì© |
BR112017014067B1 (pt) | 2015-02-27 | 2021-01-12 | Chugai Seiyaku Kabushiki Kaisha | usos de um anticorpo receptor de il-6 para no tratamento de doenças relacionadas a il-6 |
CN107727864A (zh) * | 2016-07-01 | 2018-02-23 | éŠéœå»ç§å€§åŠéå±å京äœå®å»é¢ | äžç§æ£æµè¡æž äžåŒåžžè±çŸ§åè¡é ¶åçèçœè¯çãè¯åçåå ¶å¶å€æ¹æ³ |
MX2019001448A (es) | 2016-08-05 | 2019-09-13 | Chugai Pharmaceutical Co Ltd | Composicion para profilaxis o tratamiento de enfermedades relacionadas con interleucina 8 (il-8). |
JP7185884B2 (ja) | 2017-05-02 | 2022-12-08 | åœç«ç 究éçºæ³äººåœç«ç²Ÿç¥ã»ç¥çµå»çç 究ã»ã³ã¿ãŒ | ïœïŒïŒåã³å¥œäžçã®é¢é£ããçŸæ£ã®æ²»çå¹æã®äºæž¬åã³å€å®æ¹æ³ |
WO2019161491A1 (en) | 2018-02-20 | 2019-08-29 | Prominent Medical Inc. | Aluminum oxide surfaces and interface molecules |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS6060557A (ja) * | 1983-09-13 | 1985-04-08 | Eisai Co Ltd | ïœïœïœïœâïŒã®æž¬å®æ¹æ³ããã³è©Šè¬ |
-
1984
- 1984-10-15 US US06/661,187 patent/US4769320A/en not_active Expired - Lifetime
-
1985
- 1985-10-15 AT AT85307407T patent/ATE52141T1/de not_active IP Right Cessation
- 1985-10-15 EP EP85307407A patent/EP0182495B1/en not_active Expired - Lifetime
- 1985-10-15 DE DE8585307407T patent/DE3577233D1/de not_active Expired - Fee Related
- 1985-10-15 JP JP60229763A patent/JPS61117457A/ja active Granted
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US11359009B2 (en) | 2015-12-25 | 2022-06-14 | Chugai Seiyaku Kabushiki Kaisha | Anti-myostatin antibodies and methods of use |
US11608374B2 (en) | 2017-01-30 | 2023-03-21 | Chugai Seiyaku Kabushiki Kaisha | Anti-sclerostin antibodies and methods of use |
Also Published As
Publication number | Publication date |
---|---|
US4769320A (en) | 1988-09-06 |
ATE52141T1 (de) | 1990-05-15 |
DE3577233D1 (de) | 1990-05-23 |
JPS61117457A (ja) | 1986-06-04 |
EP0182495B1 (en) | 1990-04-18 |
EP0182495A1 (en) | 1986-05-28 |
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