JPH0438399B2 - - Google Patents
Info
- Publication number
- JPH0438399B2 JPH0438399B2 JP12926184A JP12926184A JPH0438399B2 JP H0438399 B2 JPH0438399 B2 JP H0438399B2 JP 12926184 A JP12926184 A JP 12926184A JP 12926184 A JP12926184 A JP 12926184A JP H0438399 B2 JPH0438399 B2 JP H0438399B2
- Authority
- JP
- Japan
- Prior art keywords
- amino acid
- carbamyl
- present
- bacterial cells
- yin
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000008575 L-amino acids Chemical class 0.000 claims description 14
- 229940024606 amino acid Drugs 0.000 claims description 14
- 230000001580 bacterial effect Effects 0.000 claims description 11
- 238000004519 manufacturing process Methods 0.000 claims description 9
- OUYCCCASQSFEME-QMMMGPOBSA-N L-tyrosine Chemical compound OC(=O)[C@@H](N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-QMMMGPOBSA-N 0.000 claims description 5
- 244000005700 microbiome Species 0.000 claims description 5
- 150000001413 amino acids Chemical class 0.000 claims description 4
- 229960004441 tyrosine Drugs 0.000 claims description 3
- QDGAVODICPCDMU-UHFFFAOYSA-N 2-amino-3-[3-[bis(2-chloroethyl)amino]phenyl]propanoic acid Chemical compound OC(=O)C(N)CC1=CC=CC(N(CCCl)CCCl)=C1 QDGAVODICPCDMU-UHFFFAOYSA-N 0.000 claims description 2
- IFGCUJZIWBUILZ-UHFFFAOYSA-N sodium 2-[[2-[[hydroxy-(3,4,5-trihydroxy-6-methyloxan-2-yl)oxyphosphoryl]amino]-4-methylpentanoyl]amino]-3-(1H-indol-3-yl)propanoic acid Chemical compound [Na+].C=1NC2=CC=CC=C2C=1CC(C(O)=O)NC(=O)C(CC(C)C)NP(O)(=O)OC1OC(C)C(O)C(O)C1O IFGCUJZIWBUILZ-UHFFFAOYSA-N 0.000 claims description 2
- COLNVLDHVKWLRT-QMMMGPOBSA-N L-phenylalanine Chemical compound OC(=O)[C@@H](N)CC1=CC=CC=C1 COLNVLDHVKWLRT-QMMMGPOBSA-N 0.000 claims 1
- QIVBCDIJIAJPQS-VIFPVBQESA-N L-tryptophane Chemical compound C1=CC=C2C(C[C@H](N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-VIFPVBQESA-N 0.000 claims 1
- QIVBCDIJIAJPQS-UHFFFAOYSA-N Tryptophan Natural products C1=CC=C2C(CC(N)C(O)=O)=CNC2=C1 QIVBCDIJIAJPQS-UHFFFAOYSA-N 0.000 claims 1
- 229960005190 phenylalanine Drugs 0.000 claims 1
- COLNVLDHVKWLRT-UHFFFAOYSA-N phenylalanine Natural products OC(=O)C(N)CC1=CC=CC=C1 COLNVLDHVKWLRT-UHFFFAOYSA-N 0.000 claims 1
- 229960004799 tryptophan Drugs 0.000 claims 1
- OUYCCCASQSFEME-UHFFFAOYSA-N tyrosine Natural products OC(=O)C(N)CC1=CC=C(O)C=C1 OUYCCCASQSFEME-UHFFFAOYSA-N 0.000 claims 1
- 210000004027 cell Anatomy 0.000 description 13
- 238000000034 method Methods 0.000 description 7
- 239000000243 solution Substances 0.000 description 7
- 238000006243 chemical reaction Methods 0.000 description 4
- 239000000047 product Substances 0.000 description 4
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 3
- 102000004190 Enzymes Human genes 0.000 description 3
- 108090000790 Enzymes Proteins 0.000 description 3
- 229910021380 Manganese Chloride Inorganic materials 0.000 description 3
- GLFNIEUTAYBVOC-UHFFFAOYSA-L Manganese chloride Chemical compound Cl[Mn]Cl GLFNIEUTAYBVOC-UHFFFAOYSA-L 0.000 description 3
- 238000004458 analytical method Methods 0.000 description 3
- 238000004166 bioassay Methods 0.000 description 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 description 3
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 3
- 238000004128 high performance liquid chromatography Methods 0.000 description 3
- 235000002867 manganese chloride Nutrition 0.000 description 3
- 239000011565 manganese chloride Substances 0.000 description 3
- 229940099607 manganese chloride Drugs 0.000 description 3
- 235000013372 meat Nutrition 0.000 description 3
- 230000000813 microbial effect Effects 0.000 description 3
- 239000002994 raw material Substances 0.000 description 3
- NWLXJVDJMARXSP-UHFFFAOYSA-N 2-(carbamoylamino)-3-(1h-indol-3-yl)propanoic acid Chemical compound C1=CC=C2C(CC(NC(=O)N)C(O)=O)=CNC2=C1 NWLXJVDJMARXSP-UHFFFAOYSA-N 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 2
- 241000186063 Arthrobacter Species 0.000 description 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 2
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 description 2
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 2
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 description 2
- -1 N-carbamyl amino Chemical class 0.000 description 2
- 229910002651 NO3 Inorganic materials 0.000 description 2
- NHNBFGGVMKEFGY-UHFFFAOYSA-N Nitrate Chemical compound [O-][N+]([O-])=O NHNBFGGVMKEFGY-UHFFFAOYSA-N 0.000 description 2
- 239000008272 agar Substances 0.000 description 2
- 150000003863 ammonium salts Chemical class 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 238000005119 centrifugation Methods 0.000 description 2
- 239000007795 chemical reaction product Substances 0.000 description 2
- GVPFVAHMJGGAJG-UHFFFAOYSA-L cobalt dichloride Chemical compound [Cl-].[Cl-].[Co+2] GVPFVAHMJGGAJG-UHFFFAOYSA-L 0.000 description 2
- 239000013078 crystal Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 229960004452 methionine Drugs 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- PNLKYZVGQWCHBH-QMMMGPOBSA-N (2s)-2-(carbamoylamino)-3-(4-hydroxyphenyl)propanoic acid Chemical compound NC(=O)N[C@H](C(O)=O)CC1=CC=C(O)C=C1 PNLKYZVGQWCHBH-QMMMGPOBSA-N 0.000 description 1
- DEWDMTSMCKXBNP-UHFFFAOYSA-N 2-(carbamoylamino)-4-methylsulfanylbutanoic acid Chemical compound CSCCC(C(O)=O)NC(N)=O DEWDMTSMCKXBNP-UHFFFAOYSA-N 0.000 description 1
- 241000186073 Arthrobacter sp. Species 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- RWSOTUBLDIXVET-UHFFFAOYSA-N Dihydrogen sulfide Chemical compound S RWSOTUBLDIXVET-UHFFFAOYSA-N 0.000 description 1
- 108010010803 Gelatin Proteins 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Natural products OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- 238000003794 Gram staining Methods 0.000 description 1
- FFEARJCKVFRZRR-UHFFFAOYSA-N L-Methionine Natural products CSCCC(N)C(O)=O FFEARJCKVFRZRR-UHFFFAOYSA-N 0.000 description 1
- 229930195722 L-methionine Natural products 0.000 description 1
- 240000006024 Lactobacillus plantarum Species 0.000 description 1
- 235000013965 Lactobacillus plantarum Nutrition 0.000 description 1
- 238000005481 NMR spectroscopy Methods 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 108010046334 Urease Proteins 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 229940041514 candida albicans extract Drugs 0.000 description 1
- 125000003917 carbamoyl group Chemical group [H]N([H])C(*)=O 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- BNIILDVGGAEEIG-UHFFFAOYSA-L disodium hydrogen phosphate Chemical compound [Na+].[Na+].OP([O-])([O-])=O BNIILDVGGAEEIG-UHFFFAOYSA-L 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000000284 extract Substances 0.000 description 1
- 210000003495 flagella Anatomy 0.000 description 1
- 239000007789 gas Substances 0.000 description 1
- 239000008273 gelatin Substances 0.000 description 1
- 229920000159 gelatin Polymers 0.000 description 1
- 235000019322 gelatine Nutrition 0.000 description 1
- 235000011852 gelatine desserts Nutrition 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229940091173 hydantoin Drugs 0.000 description 1
- 150000001469 hydantoins Chemical class 0.000 description 1
- 229910000037 hydrogen sulfide Inorganic materials 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000003301 hydrolyzing effect Effects 0.000 description 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 description 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 description 1
- 238000009630 liquid culture Methods 0.000 description 1
- 229910052943 magnesium sulfate Inorganic materials 0.000 description 1
- 235000019341 magnesium sulphate Nutrition 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 229910000402 monopotassium phosphate Inorganic materials 0.000 description 1
- 235000019796 monopotassium phosphate Nutrition 0.000 description 1
- 230000004899 motility Effects 0.000 description 1
- 230000035772 mutation Effects 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 230000001590 oxidative effect Effects 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- PJNZPQUBCPKICU-UHFFFAOYSA-N phosphoric acid;potassium Chemical compound [K].OP(O)(O)=O PJNZPQUBCPKICU-UHFFFAOYSA-N 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 239000000049 pigment Substances 0.000 description 1
- NNFCIKHAZHQZJG-UHFFFAOYSA-N potassium cyanide Chemical compound [K+].N#[C-] NNFCIKHAZHQZJG-UHFFFAOYSA-N 0.000 description 1
- 238000004062 sedimentation Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- UQDJGEHQDNVPGU-UHFFFAOYSA-N serine phosphoethanolamine Chemical compound [NH3+]CCOP([O-])(=O)OCC([NH3+])C([O-])=O UQDJGEHQDNVPGU-UHFFFAOYSA-N 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 239000008107 starch Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 238000004659 sterilization and disinfection Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 235000000346 sugar Nutrition 0.000 description 1
- 150000008163 sugars Chemical class 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 238000002604 ultrasonography Methods 0.000 description 1
- 239000012138 yeast extract Substances 0.000 description 1
Landscapes
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Priority Applications (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12926184A JPS619293A (ja) | 1984-06-25 | 1984-06-25 | Ｌ−アミノ酸の製造方法 |
| DK161085A DK164923C (da) | 1984-04-11 | 1985-04-10 | Fremgangsmaade til fremstilling af l-alfa-aminosyrer |
| EP85302548A EP0159866B1 (en) | 1984-04-11 | 1985-04-11 | Process for production of l-amino acids |
| DE8585302548T DE3582354D1 (de) | 1984-04-11 | 1985-04-11 | Verfahren zur herstellung von l-aminosaeuren. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12926184A JPS619293A (ja) | 1984-06-25 | 1984-06-25 | Ｌ−アミノ酸の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS619293A JPS619293A (ja) | 1986-01-16 |
| JPH0438399B2 true JPH0438399B2 (fi) | 1992-06-24 |
Family
ID=15005191
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP12926184A Granted JPS619293A (ja) | 1984-04-11 | 1984-06-25 | Ｌ−アミノ酸の製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS619293A (fi) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6780443B1 (en) | 2000-02-04 | 2004-08-24 | Takasago International Corporation | Sensate composition imparting initial sensation upon contact |
| JP2019507614A (ja) | 2016-02-24 | 2019-03-22 | 高砂香料工業株式会社 | 温感および／またはピリピリ感を送達する家庭日用品製品 |
-
1984
- 1984-06-25 JP JP12926184A patent/JPS619293A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS619293A (ja) | 1986-01-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CS211400B2 (en) | Method of microbiological enzymatic production of d-aminoacids | |
| EP0074095A1 (en) | Process for preparation of aspartylphenylalanine alkyl esters | |
| GB2182036A (en) | Enzymatic process for producing L-amino acids | |
| JPH0438399B2 (fi) | ||
| Sakai et al. | Formation of β-cyanoalanine by cyanide-resistant strain Enterobacter sp. 10-1 | |
| US5130240A (en) | Process for producing d-alpha-alanine and/or l-alpha-alanineamide by arthrobacter sp | |
| EP0159866B1 (en) | Process for production of l-amino acids | |
| JP2005151967A (ja) | バリダマイシンをバリエナミンおよびバリダミンに変換する新規微生物 | |
| JP3122990B2 (ja) | Ｏ−メチル−ｌ−チロシン及びｌ−３−（１−ナフチル）アラニンの製造方法 | |
| US5496715A (en) | Process for preparing indigo | |
| US5252470A (en) | D-amidase and process for producing D-α-alanine and/or L-α-alanineamide | |
| GB2075026A (en) | Process for producing l-amino and oxidase | |
| JPS6319158B2 (fi) | ||
| JPS6058068A (ja) | 新規なアミンデヒドロゲナーゼｍ | |
| KR100293585B1 (ko) | D-알파-아미노산의제조방법 | |
| JP3873512B2 (ja) | Ｄ−３−（２−ナフチル）アラニンの製造方法 | |
| JP2899071B2 (ja) | Ｌ―α―アラニンの製造法 | |
| JPH089982A (ja) | 発酵法によるｌ−アミノ酸の製造法 | |
| JP3090761B2 (ja) | 光学活性乳酸の製造法 | |
| JPS5974994A (ja) | Ｌ−フエニルアラニンの製造法 | |
| JPH0431672B2 (fi) | ||
| EP0102529A2 (en) | Process for preparation of aspartylphenylalanine alkyl esters | |
| JPS619292A (ja) | Ｌ−アミノ酸の製造方法 | |
| JPH0147996B2 (fi) | ||
| JPH01296993A (ja) | 醗酵法によるｌ−スレオニンの製造法 |