JPH04117305A - Acaricide - Google Patents

Abstract

PURPOSE:To obtain a new acaricide having excellent action on Dermatophagoides and Tarsonemidae, being a naturally occurring component, having high safety to human and animals, comprising a benzyl acetate as an active ingredient. CONSTITUTION:A new acaricide comprising a benzyl acetate as an active ingredient. Since benzyl acetate as the active ingredient of the acaricide vaporizes by itself and has acaricidal actions, benzyl acetate can continuously be scattered by self-vaporization as a composition having surface area corresponding to width of room to be sprayed. Consequently, the number of places injected with the acaricide in TATAMI (mat) can be lessened. The acaride in cotton of FUTON (thick bedquilt) can effectively be controlled and the residual acaride after treatment can be eliminated in a short time because of rapid vaporization. The acaride is safe to human and animals because of a naturally occurring substance.

Description

[Detailed description of the invention] (Industrial application field) The present invention relates to a novel acaricide.

(Prior Art) With changes in lifestyles in recent years, a large number of mites have been occurring indoors, which has become a major problem. For example, dust mites that appear and live on carpets, bedding, and the like become allergens for asthma and other conditions, and pose a major health threat. Furthermore, although the mites that live on tatami mats do not pose a direct threat to health, they cause discomfort and are a factor that induces large outbreaks of mites.

Conventionally, in order to control mites living indoors, phosphate compounds such as fenitrothion, fenthion, DDVP, diazinon, carbamate compounds such as propoxer NAC, phenyl salicylate, benzyl benzoate, DEET (N, N- Various drugs have been used, such as diethyl-3-methylbenzamide (diethyl-3-methylbenzamide).

(Problems to be Solved by the Invention) However, all of the above-mentioned mite control agents have drawbacks such as being highly toxic, expensive, and effective only against a certain range of mites.

In addition, these chemicals are not effective unless they come into contact with mites, so in order for them to be effective, they must be treated intermittently, or when treating the inside of tatami, the chemicals must be injected evenly. There was a drawback that it had to be done.

(Means for Solving the Problems) The present inventor was searching for the pharmacological action of various compounds against mites in order to obtain a new acaricide, and found that benzyl acetate has an excellent acaricidal effect. However, the present invention was completed based on the discovery that it overcomes the drawbacks of conventional mite control agents.

That is, the present invention provides an acaricide containing benzyl acetate as an active ingredient.

The acaricide of the present invention is prepared by combining this benzyl acetate with a known liquid or solid carrier, and then using a suitable agent such as an oil solution, emulsion, wettable powder, spray, aerosol, powder, granule, fumigation agent, or evaporation agent. It is adjusted by making it into a dosage form.

Examples of liquid carriers that can be used include water, alcohols such as methanol, ethanol, and isopropyl alcohol, ketones such as acetone, methyl ethyl ketone, and cyclohexanone, ethers such as tetrahydrofuran, dioxane, and dimethyl ether, hexane, kerosene, and n. Aliphatic hydrocarbons such as paraffin and solvent naphtha, aromatic hydrocarbons such as benzene and toluene.

Examples include halogenated hydrocarbons such as dichloromethane and dichloroethane, and esters such as ethyl acetate and butyl acetate.

Examples of solid carriers include silicic acid, kaolin, activated carbon, bentonite, diatomaceous earth, and talc.

Examples include inorganic powders such as clay and calcium carbonate, plant powders such as soybean flour and wheat starch, and clathrate compounds such as cyclodextrin.

The acaricide of the present invention may further contain emulsifiers, dispersants, spreading agents, stabilizers, propellants, and volatilization regulators depending on the dosage form and its necessity.

The amount of active ingredient in the acaricide of the present invention obtained as described above can be adjusted depending on the dosage form, method of use, place of use, etc., but in general, 0. .1 to 80% by weight, particularly 1 to 40% by weight is desirable.

In order to obtain a preferable acaricidal effect with the acaricide of the present invention, for example, when spraying on a carpet or the like, it is sufficient to apply the active ingredient at a rate of about 20 μm or more per square meter.

In addition, benzyl acetate, which is the active ingredient of the acaricide of the present invention, volatilizes by itself and has acaricidal action.
The composition has a surface area commensurate with the size of the room to be sprayed, and is convenient because it can be sprayed continuously only by self-volatilization. By doing so, a sufficient effect can be expected on, for example, mites in tatami mats with fewer injection points than before. In addition, it is possible to effectively control mites in bedding such as futons by volatilizing the chemical, and since the volatilization is quick, any residual chemical after treatment can be removed in a short time. obtain.

(Actions and Effects of the Invention) Benzyl acetate, which is an active ingredient of the acaricide of the present invention, has an excellent action against the Dermatophagoides mites such as Dermatophagoides nigricans and Dermatophagoides nigricans, as well as the Dermatophagoides mites, and is a natural ingredient. It is highly safe for humans and animals.

Therefore, the acaricide of the present invention can be applied safely and effectively to indoor areas such as tatami mats, carpets, floors, and hallways, bedding such as pine mattresses, futons, and pillows, and furniture such as sofa-1 storage equipment. can exterminate mites.

In particular, acaricides that utilize the self-volatile ability of benzyl acetate are extremely advantageous because they can easily exterminate indoor mites in a short time.

(Example) Next, the present invention will be explained in more detail by giving Examples and Test Examples.

Example 1 Acaricidal test
e) was used as a test insect, and the effect of the acaricide of the present invention was investigated by the dry film method shown below.

The test results are shown in Table 1.

Wataru Krenkata (1) Dry film method A fixed amount of a drug diluted with acetone to a predetermined concentration was placed in a glass vial (diameter 1 cn, height 6 dl).

After the chemical was applied uniformly to the inner surface of the container and the acetone was volatilized, a predetermined number of woolly mites were placed in the container, and the mouth was closed with breathable Teflon wrap.

The cells were stored in duplicate under conditions of relative humidity of 75% and temperature of 25°C, and the mortality rate after - days was measured.

Toad Trouble Table Example 2 Acaricidal effect by volatilization effect A filter paper with a diameter of 5.5 mm was impregnated with a chemical and placed in a petri dish of the same diameter. Meanwhile, each vial (diameter 3alI,
Height 6 aa)
ermato haoides teronyss
ius) propagation medium was added, and the mouth was closed with breathable plastic wrap.

Each mite vial and drug petri dish were placed in a 500s+4 flask, and the mouth of the flask was sealed with plastic wrap. - After being left for a day, the mites were observed to be alive or dead, and the acaricidal activity by volatilization of the chemical was determined. The results are shown in Table 2.

Table 2 As is clear from the results, benzyl acetate has strong insecticidal activity in its volatile components, unlike conventional acaricides.

Example 3 Spray-type acaricide 20 g of benzyl acetate, 130 g of ethanol, and 150 g of liquefied petroleum gas were filled into an aerosol pressure can according to a conventional method to obtain an acaricide.

Example 4 Sheet type acaricide A miticide sheet was obtained by impregnating a filter paper with a diameter of 11 (!l) with 0.5 g of benzyl acetate.

Test Example 1 A 1Q flask was filled with 0.5 g of a propagation medium for the mites, and the acaricide obtained in Example 3 was sprayed onto the flask for 3 seconds. After leaving it for one day, a portion of the culture medium was taken and the acaricidal rate was measured, and the acaricidal rate was approximately 100%.

Test Example 2 The acaricidal sheet obtained in Example 4 was placed in a glass container, an 8 x 8 m carpet was placed on top of the sheet, and 0.5 g of a breeding medium for woolly mites was added. After leaving the lid on for one day, the number of live mites was measured to determine the mite control rate. As a result, the mite control rate was almost 100%, and sufficient efficacy was obtained.

Test Example 3 The mite-killing sheet obtained in Example 4 was placed in a glass container, and 2 g of cotton was placed on top of it. To this was added 1 g of a breeding medium for woolly mites, and after leaving it for one day with a lid on, the number of living mites was measured to determine the mite control rate.

As a result, the mite control rate was almost 100%, indicating sufficient efficacy.

that's all

Claims (1)

[Claims] Acaricide containing benzyl acetate as an active ingredient.