JPS61268604A - Insecticidal propellant - Google Patents

Abstract

PURPOSE:An insecticidal propellant having extremely improved properties with respect to a countermeasure of resistance, obtained by using a compound agent of a pyrethroid and a carbamate agent, and an ethylene glycol monoalkyl ether solvent having a specific boiling point, etc. as a solvent for preparing an insecticidal stock solution. CONSTITUTION:An insecticidal propellant obtained by packing a content consisting of <=10wt% insecticidal stock solution obtained by adding an ethylene glycol monoalkyl ether or an ethylene glycol dialkyl ether solvent (e.g., methyl Cellosolve, etc.) having >=80 deg.C boiling point as a solvent for preparing an insecti cidal stock solution to a mixture of a pyrethroid shown by the formula (X is methyl or chloro; R is H or cyano) and a carbamate compound [preferably 3-(2-methoxyphenyl)-5-methyxy-1,3,4,-oxadiazol-2-one] and >=90wt% incombustible propellant into a pressure container at an inner pressure of 3.0-7.0kg/cm<2>/25 deg.C, and attaching a valve to jet the whole amount of the content at >=1ml per second to the pressure container.

Description

DETAILED DESCRIPTION OF THE INVENTION A mixture of a compound represented by the formula (wherein, X represents a methyl group or a chlorine atom, and R represents a hydrogen atom or a cyano group) and a carbamate-based compound has ethylene having a boiling point of 80°C or higher. The contents consisting of 10% or less of an insecticidal stock solution containing a glycol monoalkyl ether or ethylene glycol dialkyl ether solvent and 90% or more of a nonflammable propellant are heated to an internal pressure of 3.0 to 7.0 Kg/cd. /25°
The present invention relates to an insecticidal propellant characterized by comprising a pulp that is filled into a pressure-resistant container and injects the entire content at a rate of 1 or more per second.

The pyrethroid compound represented by the general formula (I) exhibits extremely excellent insecticidal effects against various sanitary pests and agricultural and horticultural pests, while its toxicity to warm-blooded animals is low, and it has already been used as an insecticide for household use, epidemic prevention, and agriculture. It is widely used in practical applications.

Until now, it has been considered difficult to develop resistance to these pyrethroids, and in fact, there has been no problem in terms of control in Japan, but houseflies in northern Europe and the diamondback moth in Southeast Asia have developed resistance to pyrethroid agents. Considering the emergence of new strains and the tenacity shown by living organisms to ensure the survival of their species, it is considered appropriate to take measures based on the possibility of resistance development in Japan as well. Moreover, the development of these pyrethroid resistances is not dependent on the metabolic system, but involves a mechanism based on reduced neural sensitivity, and as a result, the phenomenon of pyrethroid cross-resistance has appeared. It has become important to develop applications, including the mixed use of pyrethroids and drugs with different physiological effects, such as pyrethroids and carbamates.

Therefore, the present inventors preferably used a pyrethroid of the general formula (■) and a carbamate agent, 3-(2-methoxyphenyl)-
We investigated a mixture with 5-methoxy-1,3,4-year-old xadiazol-2-one, and as a result of extensive research, we found that when this mixture was used as an aerosol-type insecticidal propellant, the synergistic effect It is not only effective but also extremely excellent in terms of resistance measures, and furthermore, as a solvent for preparing the insecticidal stock solution.
We have completed the present invention by discovering that ethylene glycol monoalkyl ether or ethylene glycol dialkyl ether solvents having a boiling point of 80°C or higher are extremely useful in terms of solubility, stability of active ingredients, etc. The pyrethroid of general formula (I) used as an active ingredient in the present invention is already known and is solid or liquid at room temperature. Examples of the compounds are shown below.

In addition, any pyrethroid has two asymmetric carbon atoms in the acid moiety, and if R is a cyano group, it further has one asymmetric carbon,
Although there are optical isomers based on these, each isomer or a mixture thereof is naturally included in the present invention.

(1) 3'-phenoxybenzyl chrysanthemate (
Phenothrin) (2) 3' 7zTuxi α'-cyanobenzyl chrysanthemate (Cyphenothrin)
(3) 3'-phenoxybenzyl 2,2-dimethyl-
3-(2,2-290 vinyl)cyclopropanecarboxylate (permethrin) (4) 3'--y enoxy-α'-cyanobenzyl 2
,2-dimethyl-3-(2,2-dichlorovinyl)cyclopropanecarboxylate (cypermethrin) On the other hand, among the carbamate compounds used in the present invention, 3-(2-methoxyphenyl)-5- Methoxy-1,3,4-oxadiazogalley-2-one is a recently developed product that is solid at room temperature (m, p, 77°C
), and compared to insecticidal ingredients such as pyrethroid compounds, it is less soluble in paraffin-based solvents and alcohol-based solvents.
It has a sticky property.

The present inventors investigated various types of combinations of the above-mentioned pyrethroid and carbamate agent, and as a result, discovered that the combination of the above-mentioned pyrethroid and carbamate agent was most advantageous for application to an aerosol-type insecticidal spray.

That is, conventionally commonly used insecticidal methods include the aerosol type and the smoke type, but the former method is limited to a small space, and the latter method has various drawbacks as described below.

1. Either mix the insecticidal component with a combustion agent and eject the insecticide by using the combustion heat and smoke of the combustion agent, or pack the insecticide component and organic foaming agent together and heat the mixture indirectly to generate organic foam. The mechanism is such that the agent is thermally decomposed and fumigated by the action of the thermally decomposed gas, and when the insecticidal component comes into contact with high temperatures, loss due to thermal decomposition is unavoidable.

&Depending on the properties of the insecticidal component, it may not be stable over time because it is mixed with a highly active base material.

3. Methods that involve combustion pose a risk of fire.

The present invention is a high-concentration, short-time space treatment agent designed to eliminate these drawbacks.

To explain the present invention in more detail, the content composition consists of an insecticidal stock solution and a non-flammable propellant in a weight ratio of 10% or less for the insecticide stock solution and 90% or more for the propellant, and the solvent for preparing the stock solution has a boiling point. Ethylene glycol monoalkyl ether or ethylene glycol dialkyl ether solvents having a temperature of 80° C. or higher are most suitable from the viewpoint of solubility of the carbamate agent, formulation stability, etc.

Furthermore, the container has a diameter of 0.3 mm or more, preferably α4~1
．． Internal pressure of 3.0 to 7.0 Ky/ci due to special pulp with 0 mm injection port.

It became possible to inject the entire amount of the contents at a rate of 1 or more per second at 725°C.

In addition, we investigated the distribution of the insecticidal ingredients that settled in the treated area after spraying compared to the smoke agent type, and found that the insecticidal propellant of the present invention type not only has good diffusivity but also has the ability to penetrate into narrow spaces such as cracks and gaps. It was confirmed that the type of the present invention has excellent permeability, and the recovery rate of the insecticidal component calculated from the amount of deposited sediment is several orders of magnitude higher than the smoke type.

This is because among the insecticidal ingredients, the carbamate agent particularly used in the present invention has poor thermal stability, and therefore, when applied to a smoking agent, there is a large loss due to thermal decomposition during heating.

By using the insecticidal propellant of the present invention obtained in this manner, for example, a 100-volume one, it is possible to easily dispose of a room of 6 to 8 tatami mats in less than 3 minutes without worrying about fire, and also to eliminate cockroaches, flies, mosquitoes, etc. It has extremely great practical advantages, such as its high extermination effect against indoor pests such as bed bugs and mites.

In particular, the insecticidal effect on cockroaches that have developed resistance to pyrethroids is remarkable, and the effect of the mixture in the insecticidal propellant of the present invention goes beyond simply adding the lethality of the carbamate agent to provide a highly synergistic effect. The findings are completely unexpected from conventional smoke application.

One of the reasons for this is the contribution of the solvent used in the present invention,
For example, it is possible to improve the permeability of drugs into the insect body.

Examples of the ethylene glycol monoalkyl ether solvent having a boiling point of 80°C or higher used in the present invention include methyl cellosolve, ethyl heptarosol, isopropyl cellosolve, and dimethyl cellosolve.

Examples include diethyl cellosolve, but are not limited to these.

On the other hand, nonflammable propellants used in the present invention include various fluorocarbon-based propellants and nitrogen gas.

In addition to carbon dioxide gas, mixtures of fluorocarbons, liquefied petroleum gas, and dimethyl ether can also be used as long as they are within the range of nonflammable gases.

A particularly useful propellant is 70 tons. Freon 12,70 ton 2
2. It is selected from dimethyl ether and mixed to suit the conditions.

The size of the container for the insecticidal propellant of the present invention is appropriately determined depending on the intended application space, but a 100 to 200 can is usually suitable.

The injection pulp provided in the container has an injection port with a diameter of 0.3 mm or more, but the internal pressure is 3.0 to 7.0 Kg/cd/
The shape is not particularly limited as long as the content can be injected at 1rne or more per second at 25°C.

For example, you can install several injection ports, set the injection angle at any angle other than upward, or rotate the injection ports to spray evenly into the room. It is useful to have a device that delays the actual injection of the drug so that the person does not inhale the drug during use.

The present invention also uses piperonyl ptoxide, octachlorodipropyl ether, imbornyl thiocyanoacetate, and N-(2-ethylhexyl)-bicyclo[2°2.1]-hebutoxide, which are efficacy enhancers for the above insecticides. -5-
En-2,3-dicarboximide, N-(2-ethylhexyl)-1-isopropyl-4-methylbicyclo(
2,2,2) Oct-5-ene-2,3-dicarboximide and β-butoxy-β'-thiocyanodiethyl ether and insect repellent D), R-11,R-
326, dibutyl succinate, dibutyl phthalate,
Dimethyl phthalate and the like can also be mixed.

In addition to the above, stabilizers, fragrances, fungicides, acaricides, other insecticides such as pyrethroids such as allethrin, 7-umethrin, 7-tarthrin, and empenthrin, organic compounds such as fenitrothion, DI)VP, diazinon, and propafos. It is also possible to use a phosphorus agent or the like in combination, and a multipurpose composition with excellent effects can be obtained.

The insecticidal propellant of the present invention can be used indoors not only for susceptible pests but also for organic phosphorus agent, carbamate agent resistant or Kd
Various r-type pests such as flies.

It is particularly useful for exterminating mosquitoes, cockroaches, bedbugs, mites, etc., but it is also useful for exterminating grain pests such as brown elephants and aphids in plastic haxes.

It can also be applied to control agricultural pests such as scale insects and armyworms.

Next, examples and experimental examples of the present invention will be shown, but the present invention is not limited to the following examples unless it exceeds the gist thereof.

Example: 100m of insecticidal ingredients, solvent, and propellant with the composition shown in the table below.
eFill into an aerosol container, make a jet nozzle & Product A; 3-(
2-methoxyphenyl)-5-methoxy-1,3,4-
Xadiazol-2-one The following propellant was prepared as a control for the insecticidal propellant of the present invention.

Experimental Example 1 An insecticidal propellant prepared in the same manner as in the example except that a pressure-resistant glass bottle was used instead of the aerosol container was stored in a refrigerator at -5°C, and the liquid state was observed after 2 weeks to determine the solubility of the insecticidal ingredient. I investigated and found the following.

As a result of the test, the solubility of the insecticidal components of the propellants of the present invention was excellent, but on the other hand, precipitation of insoluble matter was observed in the propellants containing no solvent [1 color] and those using ethanol [1-Et]. . Note that ethanol can be used with other solvents such as trichloroethane.

The same thing happened when I changed to F113.

This insecticidal spray agent and a conventional smoke agent were applied in a room with an area of 16 mm and a height of 15 meters, and the diffusibility of the insecticidal components and their permeability between objects were compared.

In other words, the injection point is at the center of the room, and is 1.6 m.

& 2 glass plates of 20σ square each at a distance of 5m (one is left open, the other glass plate is 20cm with a belt-shaped slit of α5 x 10m on the top surface)
20 hours later, the amount of precipitated insect-killing ingredients was measured.

The test samples were the insecticidal propellants (1) and [2] of the present invention prepared in the examples, and commercially available organic foaming agent type smoking agents [Smoke-1] and [Smoke-2] that were replaced with insecticidal ingredients of the same formulation.
] was used.

The value in parentheses indicates the recovery rate relative to the theoretical sedimentation amount.

As a result of the test, the insecticidal propellant of the present invention had a distance of 1.5 m.

2] Approximately 5 m compared to the theoretical sedimentation amount at any point
It showed a high recovery rate of 0% (oven) and had superior dispersion power compared to smoking agents.

In the case of smoking agents, it was confirmed that the recovery rate of carbamate agents was particularly poor, and the decomposition loss due to heat was large. Furthermore, the processing time of the insecticidal propellant of the present invention is the same as that of a smoke agent, and the insecticidal propellant of the present invention has excellent penetration power between objects, so it has been recognized that it is extremely efficient.

Experimental Example 3゜The area used in Experimental Example 2 is 16 tr? A storage box was placed in the four corners of a room with a height of 2.5 m, and approximately 20 susceptible and pyrethroid-resistant German cockroaches (female) were released in two locations each. A wooden shelter was installed inside the clothing box.

A test sample was sprayed from the center of the room, exposed for 24 hours, German cockroaches were collected, and the mortality rate after 72 hours was determined as follows.

[Smoking-1] and [Smoking-5] respectively indicate commercially available organic foaming type smokers that were replaced with insecticidal ingredients of the same formulation as (13 and [5]).

As a result of the test, the insecticidal propellant of the present invention showed a remarkable insecticidal effect on susceptible and resistant German cockroaches, and from the comparison between [1] and the controls [5] and [6], it was found that the mixed use of a pyrethroid agent and a carbamate agent This synergistic effect is characteristic of this insecticidal propellant type and was not observed with smoke agents.

Furthermore, from a comparison between [1] and [1 color], it was found that the ethylene glycol monoalkyl ether or ethylene glycol dialkyl ether solvent used as a solvent in the present invention is useful in terms of effect development.

Claims (1)

[Claims] General formula (I) ▲Mathematical formulas, chemical formulas, tables, etc.▼---(I) (In the formula, X represents a methyl group or a chloro atom, and R represents a hydrogen atom or a cyano group. ) and a carbamate compound, 10% or less of an insecticidal stock solution containing ethylene glycol monoalkyl ether or ethylene glycol dialkyl ether solvent with a boiling point of 80°C or higher, and 90% or more of a nonflammable propellant. The contents consisting of
1. An insecticidal propellant, which is filled into a pressure-resistant container and is equipped with a valve that sprays the entire content at a rate of 1 ml or more per second.