JPH03258705A - Miticide - Google Patents

Abstract

PURPOSE:To obtain a miticide exhibiting excellent miticidal action against dermatophagoides and dust mite and continuously exerting its effect only by the self-dissipation action by using a carbamic acid alkyl ester derivative as an active component. CONSTITUTION:The objective miticide contains 1-40wt.% of a compound of formula (R1 and R2 are H or CH3; R3 is 1-4C alkyl) as an active component and formed in the form of an oil, emulsion, wettable powder, spray, aerosol, powder, granule, fumigant, transpiration agent, etc., by combining with a liquid carrier, solid carrier, etc. Since the compound of formula is vaporizable by itself to exhibit miticidal action, its effect can be continuously exhibited only by its self-dissipation action by forming the agent to a composition having a surface area suitable for the area of the room to be treated. Accordingly, a sufficient effect can be attained even against mites in a mat by injecting the agent into the mat and the number of injection points can be decreased compared with the number necessary for conventional agent. Since the agent is quickly dissipated, the residual agent in beddings can be eliminated in a short time.

Description

[Detailed description of the invention] (Industrial application field) The present invention relates to a novel acaricide.

(Prior Art) With changes in lifestyles in recent years, a large number of mites have been occurring indoors, which has become a major problem. For example, dust mites that appear and live on carpets, bedding, and the like become allergens for asthma and other conditions, and pose a major health threat. Furthermore, although the mites that live on tatami mats do not pose a direct threat to health, they cause discomfort and are a factor that induces large outbreaks of mites.

Conventionally, in order to control mites living indoors, phosphate compounds such as fenitrothion, fenthion, DDVP, diazinon, propoxar NAC1 and others, phenyl salicylate, benzyl benzoate, DEET (N, N
-diethyl-3-methylbenzamide).

(Problems to be Solved by the Invention) However, all of the above-mentioned mite control agents have drawbacks such as being highly toxic, expensive, and effective only against a certain range of mites.

In addition, these chemicals are not effective unless they come into contact with mites, so in order for them to be effective, they must be treated intermittently, or when treating the inside of tatami, the chemicals must be injected evenly. There was a drawback that it had to be done.

(Means for Solving the Problems) The present inventor was searching for the pharmacological action of various compounds against mites in order to obtain a new acaricide, and found 11\N-G OOR.

(However, R,, R, 4i hydrogen or methyl group, R3 is an alkyl group having 1 to 4 carbon atoms) Compounds represented by these have excellent acaricidal effects and eliminate the drawbacks of conventional mite control agents. The present invention was completed based on the discovery that

That is, the present invention provides an acaricide containing as an active ingredient a compound represented by: It provides:

The acaricide of the present invention R.

■ %-N　-COOR.

(However, R,, R□ are hydrogen or a methyl group, and R6 is an alkyl group having 1 to 4 carbon atoms.) The compound represented by the above is combined and blended with a known liquid or solid carrier to form oils, emulsions, wettable powders, Fouling agent, aerosol agent,
It can be adjusted by preparing a suitable dosage form such as a powder, granule, fumigation agent, or transpiration agent.

Examples of liquid carriers that can be used include water, alcohols such as methanol, ethanol, and isopropyl alcohol, ketones such as acetone, methyl ethyl ketone, and cyclohexanone, ethers such as tetrahydrofuran, dioxane, and dimethyl ether, hexane, kerosene, and n. Examples include aliphatic hydrocarbons such as paraffin and solvent naphtha, aromatic hydrocarbons such as benzene and toluene, halogenated hydrocarbons such as dichloromethane and dichloroethane, and esters such as ethyl acetate and butyl acetate.

Examples of solid carriers include silicic acid, kaolin, activated carbon, bentonite, diatomaceous earth, and talc.

Examples include inorganic powders such as clay and calcium carbonate, plant powders such as soybean flour, wheat flour, and starch, and clathrate compounds such as cyclodextrin.

The acaricide of the present invention may further contain an emulsifier, a dispersant, a spreading agent, a stabilizer, a propellant, and a volatilization regulator depending on the dosage form and its necessity.

The amount of active ingredient in the acaricide of the present invention obtained as described above can be adjusted depending on the dosage form, method of use, place of use, etc., but in general, 0. It is desirable that the amount is about 1 to 80% by weight, particularly 1 to 40% by weight.

In addition, 1, which is an active ingredient of the acaricide of the present invention, R, -N @G OOR.

(However, R,, R, is hydrogen or a methyl group, and R1 is an alkyl group having 1 to 4 carbon atoms.) Since the compound represented by these formulas volatilizes by itself and has acaricidal action, it should be sprayed on a large area of the room. The composition has a surface area suitable for
It is possible to disperse it.

It's convenient. By doing so, a sufficient effect can be expected against, for example, mites in bones, with fewer drug injection locations than before. In addition, it is possible to effectively control mites in bedding such as futons by volatilizing the chemical, and since the volatilization is quick, any residual chemical after treatment can be removed in a short time. obtain.

(Action and effect of invention) is the active ingredient of the acaricide of the present invention. R5 N-GOOR.

(However, RlR is hydrogen or a methyl group, and R2 is an alkyl group having 1 to 4 carbon atoms.) The compound represented by these formulas has an excellent action against Dermatophagoides mites, such as Dermatophagoides nigricans, and Dermatophagoides mites.

The acaricide of the present invention can be used indoors such as tatami mats, carpets, floors, hallways, bedding such as pine mattresses, futons, pillows, sofas, etc.
By applying it to furniture such as storage utensils, mites can be effectively exterminated.

especially, N-COOR.

(However, R, and R are hydrogen or methyl groups, and RJ is an alkyl group having 1 to 4 carbon atoms.) Acaricides that utilize the self-volatilizing ability of compounds represented by the following can easily be used indoors in a short time. It is extremely advantageous because it can exterminate mites.

(Example) Next, the present invention will be explained in more detail by giving Examples and Test Examples.

Example 1 Acaricidal test CDerrrrato haoid
es 6μ! The effectiveness of the acaricide of the present invention was investigated using the volatilization method shown below using the woolly mite (Escentiae escentiae) as the test insects.

The test results are shown in Table 1.

Melyujuku 20 to 30 woolen mites or brown spider mites are placed in a glass vial with an inner diameter of 1 am and a height of 6 aa.
The mouth of the vial was covered with a breathable Teflon film. Place a certain amount of the test sample in a small Petri dish, and
It was placed in the IQ beaker together with a vial containing saturated saline. The vial containing the mites was placed in a beaker with the film-covered mouth facing up.The beaker's mouth was covered with a non-porous film and the temperature was 25°C.
The sample was left standing for 24 hours under the following conditions and observed under a microscope.

(Margin below) result Table 1 -N,N-diethyl-3-methylbenzamide or more

Claims (1)

[Claims] ▲There are mathematical formulas, chemical formulas, tables, etc.▼ (However, R_1 and R_2 are hydrogen or methyl groups, R_
3 is an acaricide containing a compound represented by C1-C4 alkyl group as an active ingredient.