JPH0378875B2 - - Google Patents
Info
- Publication number
- JPH0378875B2 JPH0378875B2 JP61243231A JP24323186A JPH0378875B2 JP H0378875 B2 JPH0378875 B2 JP H0378875B2 JP 61243231 A JP61243231 A JP 61243231A JP 24323186 A JP24323186 A JP 24323186A JP H0378875 B2 JPH0378875 B2 JP H0378875B2
- Authority
- JP
- Japan
- Prior art keywords
- substance
- kbs2
- amino acid
- ether
- absorption spectrum
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000126 substance Substances 0.000 claims description 30
- WEVYAHXRMPXWCK-UHFFFAOYSA-N Acetonitrile Chemical compound CC#N WEVYAHXRMPXWCK-UHFFFAOYSA-N 0.000 claims description 15
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims description 14
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 13
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 10
- 239000000843 powder Substances 0.000 claims description 8
- 241000193830 Bacillus <bacterium> Species 0.000 claims description 7
- CSCPPACGZOOCGX-UHFFFAOYSA-N Acetone Chemical compound CC(C)=O CSCPPACGZOOCGX-UHFFFAOYSA-N 0.000 claims description 6
- XEKOWRVHYACXOJ-UHFFFAOYSA-N Ethyl acetate Chemical compound CCOC(C)=O XEKOWRVHYACXOJ-UHFFFAOYSA-N 0.000 claims description 6
- OKKJLVBELUTLKV-UHFFFAOYSA-N Methanol Chemical compound OC OKKJLVBELUTLKV-UHFFFAOYSA-N 0.000 claims description 6
- 238000000862 absorption spectrum Methods 0.000 claims description 6
- 150000001413 amino acids Chemical class 0.000 claims description 6
- 239000000203 mixture Substances 0.000 claims description 5
- 241000894006 Bacteria Species 0.000 claims description 4
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims description 4
- BDERNNFJNOPAEC-UHFFFAOYSA-N propan-1-ol Chemical compound CCCO BDERNNFJNOPAEC-UHFFFAOYSA-N 0.000 claims description 4
- 229910052757 nitrogen Inorganic materials 0.000 claims description 3
- 238000004380 ashing Methods 0.000 claims description 2
- 238000006243 chemical reaction Methods 0.000 claims description 2
- 238000012258 culturing Methods 0.000 claims description 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 2
- 238000000921 elemental analysis Methods 0.000 claims description 2
- 239000000194 fatty acid Substances 0.000 claims description 2
- 229930195729 fatty acid Natural products 0.000 claims description 2
- 150000004665 fatty acids Chemical class 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- FEMOMIGRRWSMCU-UHFFFAOYSA-N ninhydrin Chemical compound C1=CC=C2C(=O)C(O)(O)C(=O)C2=C1 FEMOMIGRRWSMCU-UHFFFAOYSA-N 0.000 claims description 2
- 239000003208 petroleum Substances 0.000 claims description 2
- 239000002904 solvent Substances 0.000 claims description 2
- 238000010521 absorption reaction Methods 0.000 claims 2
- 239000002244 precipitate Substances 0.000 description 10
- 239000012153 distilled water Substances 0.000 description 7
- 238000004128 high performance liquid chromatography Methods 0.000 description 6
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 4
- DTQVDTLACAAQTR-UHFFFAOYSA-N Trifluoroacetic acid Chemical compound OC(=O)C(F)(F)F DTQVDTLACAAQTR-UHFFFAOYSA-N 0.000 description 4
- 230000000844 anti-bacterial effect Effects 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000012043 crude product Substances 0.000 description 3
- 239000000047 product Substances 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 2
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 2
- 238000002835 absorbance Methods 0.000 description 2
- 230000000843 anti-fungal effect Effects 0.000 description 2
- 239000003125 aqueous solvent Substances 0.000 description 2
- 229940041514 candida albicans extract Drugs 0.000 description 2
- 239000008367 deionised water Substances 0.000 description 2
- 229910021641 deionized water Inorganic materials 0.000 description 2
- 239000000706 filtrate Substances 0.000 description 2
- 238000004108 freeze drying Methods 0.000 description 2
- 239000002609 medium Substances 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 239000006228 supernatant Substances 0.000 description 2
- 239000012138 yeast extract Substances 0.000 description 2
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- 102000016938 Catalase Human genes 0.000 description 1
- 108010053835 Catalase Proteins 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- 238000003794 Gram staining Methods 0.000 description 1
- 102000004316 Oxidoreductases Human genes 0.000 description 1
- 108090000854 Oxidoreductases Proteins 0.000 description 1
- 238000005273 aeration Methods 0.000 description 1
- 229940121375 antifungal agent Drugs 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000000385 dialysis solution Substances 0.000 description 1
- 238000004090 dissolution Methods 0.000 description 1
- 238000010828 elution Methods 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 239000007788 liquid Substances 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 239000000377 silicon dioxide Substances 0.000 description 1
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 1
- 235000017557 sodium bicarbonate Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 238000001228 spectrum Methods 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 238000003756 stirring Methods 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
Landscapes
- Compounds Of Unknown Constitution (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61243231A JPS6399085A (ja) | 1986-10-15 | 1986-10-15 | 物質ｋｂｓ２−ｐ１０２及びその製造法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP61243231A JPS6399085A (ja) | 1986-10-15 | 1986-10-15 | 物質ｋｂｓ２−ｐ１０２及びその製造法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS6399085A JPS6399085A (ja) | 1988-04-30 |
| JPH0378875B2 true JPH0378875B2 (enrdf_load_stackoverflow) | 1991-12-17 |
Family
ID=17100785
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP61243231A Granted JPS6399085A (ja) | 1986-10-15 | 1986-10-15 | 物質ｋｂｓ２−ｐ１０２及びその製造法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS6399085A (enrdf_load_stackoverflow) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0601187A4 (en) * | 1992-03-31 | 1994-09-21 | Higeta Shoyu Kk | Novel antibiotic and production and use thereof. |
-
1986
- 1986-10-15 JP JP61243231A patent/JPS6399085A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS6399085A (ja) | 1988-04-30 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| SU578014A3 (ru) | Способ получени рифамицина р, , и | |
| JPH0378875B2 (enrdf_load_stackoverflow) | ||
| US4209507A (en) | Novel anti-tumor substance and preparation thereof | |
| JPH0378877B2 (enrdf_load_stackoverflow) | ||
| JPH0378874B2 (enrdf_load_stackoverflow) | ||
| JPH0378879B2 (enrdf_load_stackoverflow) | ||
| JPH0378876B2 (enrdf_load_stackoverflow) | ||
| JPH0378880B2 (enrdf_load_stackoverflow) | ||
| JPH0378878B2 (enrdf_load_stackoverflow) | ||
| US4177108A (en) | Process for producing emitanin | |
| EP0491114A1 (en) | A process for preparing new non-covalent polysaccharide-protein associations having pharmacological activity | |
| US4656037A (en) | SPF-100 and process for the preparation thereof | |
| JPS62135496A (ja) | Ｐ３物質及びその製造法 | |
| JPS62135497A (ja) | Ｐ４物質及びその製造法 | |
| US3089816A (en) | Lemacidine and process for its manufacture | |
| JPS62135495A (ja) | Ｐ２物質及びその製造法 | |
| US3297526A (en) | Process for producing coprogen and desferricoprogen | |
| JPS62135498A (ja) | ３０−２物質及びその製造法 | |
| JP3029331B2 (ja) | 動物細胞生育促進剤 | |
| JPS62135494A (ja) | Ｐ１９物質及びその製造法 | |
| JPS62270596A (ja) | 感染防御物質アラダプシン | |
| JP3560626B2 (ja) | 有用物質の回収法 | |
| JP3176672B2 (ja) | 抗ウイルス活性を有する新規なグルタールイミド系抗生物質およびその製造方法 | |
| EP0024206A2 (en) | Antitumor substance, composition comprising it and process for preparing said substance | |
| JPS6015318B2 (ja) | 新抗生物質ｓｆ−１９４２物質，その製造法およびそれを含有する抗ガン剤 |