JPH0363216A - Skin cleaner - Google Patents

Abstract

PURPOSE:To obtain a skin cosmetic providing preventing effects on stain and freckles even after washing away, providing effects of fair skin, containing hinokithiol. CONSTITUTION:A skin cleaner containing hinokithiol. Hinokithiol extracted from a hinoki oil from Taiwan or a hinoki oil from AOMORI Prefecture or prepared by synthetic method is used as the hinokithiol. The skin cleaner is the general term of toilet soap for washing face and the whole body, medicated soap, deodorant soap, body shampoo, cleansing foam, etc. In the skin cleaner, components thereof are not designated and components used for washing face and the whole body are sufficiently applied. The amount of hinokithiol blended is usually 0.002-15wt.%, preferably 0.15-5.0wt.% based on the whole amount of the skin cleaner.

Description

DETAILED DESCRIPTION OF THE INVENTION [Industrial Field of Application] The present invention relates to a cleansing material that has a whitening effect on the skin.

[Prior art and its problems] Hinokitiol has been known as an ingredient that inhibits tyrosinase activity and suppresses melanin production at low concentrations, and is used in ointments, creams, packs, emulsions, lotions, etc. (Japanese Patent Application Laid-Open No. 56-8309)
．． JP-A-56-147705, etc.).

These ointments and cosmetics are generally used to prevent spots, freckles, etc. that occur on the face and parts of the body. However, spots and freckles occur all over the body, and it is practically possible to apply these ointments and cosmetics all over the body. Furthermore, women and men who do not use cosmetics often do not like to use cosmetics such as ointments, creams, and bags on a daily basis. Therefore, by using a simple method on a daily basis, you can prevent the appearance of spots and freckles on the face and whole body, have a whitening effect on the skin of the face and whole body, and prevent the appearance of spots and freckles after sunburn caused by sunbathing. There is a need for a skin cleansing material that can mildly restore the skin's normal color, reduce skin tension, dullness, and the like.

[Means for Solving the Problem] As a result of intensive research to develop a skin cleansing material that exhibits the aforementioned effects, the present inventor has developed a skin cleansing material containing hinokitiol that can be used when washing the face or bathing. We discovered that by washing it off, you can still get a whitening effect.
The present invention has now been completed.

That is, the present invention relates to a skin cleansing material characterized by containing hinokitiol.

The present invention will be explained in detail below.

Hinokitiol applied to the present invention is the same substance as β-tuyapridine, and its chemical name is 4-isopropyl-2-hydroxy-cyclohebuta-2,4,6-trien-1-one (C+.Hs*Oz). be.

It is mainly extracted from Taiwanese cypress oil, Aomori cypress oil, etc., but those obtained by synthetic methods can also be used.

There are many clinical examples showing the effectiveness of hinokitiol. For example, it has therapeutic and preventive effects on alveolar pyorrhea and has the effect of removing bad breath, so it is used in toothpastes and medicines for treating alveolar pyorrhea.
There are clinical reports that it has a therapeutic effect on alopecia areata or a hair growth promoting effect, so there are examples of its use in hair products such as hair tonics. It has also been reported to be effective in treating tuberculosis including pulmonary tuberculosis.

In addition, hinokitiol has strong antibacterial activity and a wide range of antibacterial properties, so it also has a deodorant effect (decomposes sweat and prevents odor). Furthermore, the toxicity of hinokitiol is very low, and the L D so in mice is reported to be 781.1 mg/kg. It is a safe substance with little irritation to the skin.

The skin cleansing material provided by the present invention refers to a cleansing material for cleaning the face and whole body. For example, toilet soap, transparent soap,
Solid cleaning products such as floating stone soap, medicated soap, and deodorant effects, as well as soaps containing sodium salts such as fatty acid monoglyceride sulfuric acid, fatty acid metal clarilad, fatty acid isethionic acid ester, and dositel sulfuric acid, called Combar or Syndead bar, are the main ingredients. solid detergent,
A mildly acidic, hypoallergenic solid detergent based on N-amylglutamic acid monosodium salt, triethanolamine salt of lauryl sulfate, lauroyl sarcosine salt of lauryl polyoxyethylene sulfate, etc. Liquid or cream cleansers called "shampoo", "facial cleansers", and "full body cleansers", liquid cleansers containing organic solvents used for cleaning special stage cosmetics, and anhydrous oil-based creams used in movies and plays. Liquidifying cream used to remove dirt, W2O type and O/W type cleansing cream suitable for removing oil-based cosmetics that are the mainstream of makeup, and emulsion based cleansing cream in emulsion form. These include cleansing lotions, lotion-type cleansing lotions, and cleansing foams that remove make-up and dirt from the skin while retaining the cleansing properties of soap.

The ingredients of the skin cleansing material are not particularly specified, and any skin cleansing material may be used as long as it can be used for face and whole body cleansing. In addition, skin cleansing materials can be solid, liquid, cream, emulsion, foam, gel, etc., as long as they are used for face and whole body cleansing.
Humectants such as glycol in powder form, water-soluble polymer substances, powders such as talc, kaolin, titanium white, etc., drugs such as vitamins, preservatives, sequestering agents, bactericides,
It may also contain pigments, fragrances, etc. Naturally, these must be used within a range that does not impair the effects of the present invention.

The amount of hinokitiol to be blended is arbitrarily selected depending on the properties of the skin cleansing material, but usually hinokitiol is 0.002 to 15% by weight based on the total amount of the skin cleansing material, preferably 0.
．． It is in the range of 15 to 5.0% by weight.

Skin cleansing materials are mainly used regularly for bathing, face washing, etc. According to the present invention, the skin cleansing material containing hinokitiol can prevent and remove stains and freckles and provide a mild skin whitening effect on the face and whole body even if it is washed with water etc. after use. It is also effective against dullness and dullness of the skin, and its effects can be noticeable if used regularly.

[Example 1] The present invention will be illustrated below with reference to Examples, but the present invention is not limited to these Examples.

Example 1 (Bar soap) Lanolin 2.5% by weight Olive oil Hinokitiol Soap base Ethylenediaminetetraacetic acid Fragrance Example 2 (Liquid whole body cleansing material) Lauric acid Myristic acid Palmitic acid Oleate Lauryl jetanol 7 Midopropylene glycol Glycerin Sugar Caustic Kalihinokitiol Fragrance Dye preservative Sequestering agent 4, 0 1.0 92,5 Appropriate amount Appropriate amount 2,5% by weight 7, 5 2.5 2.5 5, 0 10, 0 5, 0 5, 0 3, 6 0, 5 The right amount, the right amount, the right amount? i'f water 55.9 Example 3 (Cleansing foam) Stearic acid 1000% by weight Valmipalmitic acid 10.0 Myristic acid
12.0 Lauric acid 4.
0 Oleic alcohol 1.5 Lanolin derivative 1.0 Glycerin
18.0 Potassium hydroxide 6.0 Hinokitiol 1.0 Flavor
, 0.5 Preservative Appropriate amount Kozue Ice 36.O Test 1 A skin whitening effect test of bar soap was conducted.

In August, 40 men who had their backs exposed for four hours on the beach were each treated with two
The participants were divided into two groups, A and H, each with 0 participants.

The bar soap of Example 1 excluding Group A hinokitiol was used for bathing for 60 days.

Group B The bar soap of Example 1 was used for bathing for 60 days.

The brightness of the sunburn was measured every 10 days using a color difference meter. The results are shown in Table 1.

Table 1 As shown in Table 1, in 30 to 60 days, the brightness of group B, which used the bar soap according to the present invention, increased more than that of group A, which did not use it, and the fair skin effect of the present invention was recognized. Furthermore, no side effects such as itching or rash occurred.

Type 2 Experience 2 The 40 women were divided into two groups, A and B, with 20 women each.

Group A The liquid whole body cleansing material from Example 2 except that hinokitiol was removed was used for bathing for 8 weeks.

Group B The liquid whole body cleansing agent of Example 2 was used during bathing for 8 weeks.

Thereafter, a sensory evaluation test was conducted using the method shown in Figure 2. 2 each
Table 3 shows the average score of 0 people.

(Mean value ± SD) Table 2 Table 3 As shown in Table 3, Group B, which used the liquid whole body cleanser of the present invention, had higher scores than Group A, which did not use it. In particular, remarkable effects on skin tension and dullness were confirmed. Furthermore, no side effects such as itching or rash occurred.

Test Example 3 Formulation Example 1 (Cream) Stearic acid 10.0% by weight Beeswax 3.0 Cetanol
8.0 Squalane 10.0
Glyceryl monostearate 3.0 Polyoxyethylene monolaurate 3. 0 Lanolin derivative 2.0 Propylene glycol 1000 Triethanolamine
1.0 Fragrance 0.5 Hinokitiol 0.5 Purified Ice
49.0 30 women, 10 each A, B, C
They were divided into three groups.

Group A was treated with a cleansing foam from Example 3 except for hinokitiol every night for 30 days, after removing the cosmetics and washing the skin, a cream from Prescription Example 1 except for hinokitiol was applied to the face.

For 30 days, Group B removed the cosmetics every night using the cleansing foam of Example 3 except for dihinokitiol, and after washing the skin, the cream according to Formulation Example 1 was applied to the face.

Group C: For 30 days, after removing cosmetics and cleaning the skin every night with the cleansing foam according to Example 3, Prescription Example 1 was applied.
A cream was applied to the face.

Thereafter, a sensory evaluation test was conducted using the method shown in Table 2. Table 4 shows the average scores of each of the 10 people.

Table 4 As shown in Table 4, it was confirmed that the cleansing foam according to the present invention has a synergistic effect on skin tension and dullness when used together with a cream containing hinokitiol, and has a skin whitening effect. I was able to confirm. Furthermore, no side effects such as itching or rash occurred.

Claims (1)

[Claims] 1. Skin cleanser characterized by containing hinokitiol