JPH0361662B2 - - Google Patents

Info

Publication number
JPH0361662B2
JPH0361662B2 JP59077372A JP7737284A JPH0361662B2 JP H0361662 B2 JPH0361662 B2 JP H0361662B2 JP 59077372 A JP59077372 A JP 59077372A JP 7737284 A JP7737284 A JP 7737284A JP H0361662 B2 JPH0361662 B2 JP H0361662B2
Authority
JP
Japan
Prior art keywords
antibiotics
water
medium
column
culture
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP59077372A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60218396A (ja
Inventor
Eiji Kondo
Yoshimi Kawamura
Takao Konishi
Koichi Matsumoto
Junichi Shoji
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shionogi and Co Ltd
Original Assignee
Shionogi and Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shionogi and Co Ltd filed Critical Shionogi and Co Ltd
Priority to JP59077372A priority Critical patent/JPS60218396A/ja
Priority to US06/719,737 priority patent/US4647693A/en
Priority to GB08509577A priority patent/GB2159150B/en
Priority to EP85104546A priority patent/EP0159004B1/en
Priority to DE198585104546T priority patent/DE159004T1/de
Priority to DE8585104546T priority patent/DE3576694D1/de
Priority to KR1019850002516A priority patent/KR930000275B1/ko
Priority to CN 85102956 priority patent/CN1011245B/zh
Publication of JPS60218396A publication Critical patent/JPS60218396A/ja
Publication of JPH0361662B2 publication Critical patent/JPH0361662B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • C12N1/205—Bacterial isolates
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
    • C12P1/02—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using fungi
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06008—Dipeptides with the first amino acid being neutral
    • C07K5/06078—Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
    • C12R2001/00—Microorganisms ; Processes using microorganisms
    • C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
    • C12R2001/625—Streptoverticillium

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Virology (AREA)
  • Mycology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP59077372A 1984-04-16 1984-04-16 抗生物質ｄｏ−２４８−ａおよびｂならびにその製造法 Granted JPS60218396A (ja)

Priority Applications (8)

Application Number Priority Date Filing Date Title
JP59077372A JPS60218396A (ja) 1984-04-16 1984-04-16 抗生物質ｄｏ−２４８−ａおよびｂならびにその製造法
US06/719,737 US4647693A (en) 1984-04-16 1985-04-03 Antibiotics DO-248-A and B and process for preparing the same
GB08509577A GB2159150B (en) 1984-04-16 1985-04-15 Antibiotics do-248-a and b and their preparation
EP85104546A EP0159004B1 (en) 1984-04-16 1985-04-15 Antibiotics do-248-a and b and process for preparing the same
DE198585104546T DE159004T1 (de) 1984-04-16 1985-04-15 Antibiotika do-248-a und b und deren verfahren zur herstellung.
DE8585104546T DE3576694D1 (de) 1984-04-16 1985-04-15 Antibiotika do-248-a und b und deren verfahren zur herstellung.
KR1019850002516A KR930000275B1 (ko) 1984-04-16 1985-04-15 항생물질 do-248-a 및 b의 제조방법
CN 85102956 CN1011245B (zh) 1984-04-16 1985-04-19 抗生素do-248-a和do-248-b的生产方法

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP59077372A JPS60218396A (ja) 1984-04-16 1984-04-16 抗生物質ｄｏ−２４８−ａおよびｂならびにその製造法

Publications (2)

Publication Number Publication Date
JPS60218396A JPS60218396A (ja) 1985-11-01
JPH0361662B2 true JPH0361662B2 (enExample) 1991-09-20

Family

ID=13632065

Family Applications (1)

Application Number Title Priority Date Filing Date
JP59077372A Granted JPS60218396A (ja) 1984-04-16 1984-04-16 抗生物質ｄｏ−２４８−ａおよびｂならびにその製造法

Country Status (6)

Country Link
US (1) US4647693A (enExample)
EP (1) EP0159004B1 (enExample)
JP (1) JPS60218396A (enExample)
KR (1) KR930000275B1 (enExample)
DE (2) DE159004T1 (enExample)
GB (1) GB2159150B (enExample)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH08505854A (ja) * 1993-01-14 1996-06-25 マガイニン ファーマシューティカルズ，インク． 修飾された末端を有するアミノ酸及びペプチド
US5654451B1 (en) * 1993-01-14 2000-02-22 Magainin Pharma Amino acids and peptides having modified c-terminals and modified n-terminals
AUPN115095A0 (en) * 1995-02-15 1995-03-09 Butt, Henry Lawrence Analysis of and compositions and methods for the treatment of disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3994965A (en) * 1974-08-09 1976-11-30 Pfizer Inc. D-N-(guanylureidoacetyl)-α-aminophenyl acetic acid and D-N-(guanylureidoacetyl)-α-aminophenyl acetyl chloride
JPS59144717A (ja) * 1983-02-07 1984-08-18 Microbial Chem Res Found 鎮痛剤

Also Published As

Publication number Publication date
GB8509577D0 (en) 1985-05-22
GB2159150A (en) 1985-11-27
US4647693A (en) 1987-03-03
EP0159004A3 (en) 1987-08-12
KR930000275B1 (ko) 1993-01-14
EP0159004B1 (en) 1990-03-21
EP0159004A2 (en) 1985-10-23
DE3576694D1 (de) 1990-04-26
JPS60218396A (ja) 1985-11-01
KR850007277A (ko) 1985-12-02
DE159004T1 (de) 1986-02-27
GB2159150B (en) 1987-07-22

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