JPH0358270B2 - - Google Patents

Info

Publication number
JPH0358270B2
JPH0358270B2 JP60081493A JP8149385A JPH0358270B2 JP H0358270 B2 JPH0358270 B2 JP H0358270B2 JP 60081493 A JP60081493 A JP 60081493A JP 8149385 A JP8149385 A JP 8149385A JP H0358270 B2 JPH0358270 B2 JP H0358270B2
Authority
JP
Japan
Prior art keywords
concentration
present
medium
cells
plasminogen activator
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP60081493A
Other languages
English (en)
Japanese (ja)
Other versions
JPS60259187A (ja
Inventor
Wai Chan Shamu
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Miles Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Inc filed Critical Miles Inc
Publication of JPS60259187A publication Critical patent/JPS60259187A/ja
Publication of JPH0358270B2 publication Critical patent/JPH0358270B2/ja
Granted legal-status Critical Current

Links

Landscapes

  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP60081493A 1984-04-19 1985-04-18 プラスミノーゲン活性化因子を増収する方法 Granted JPS60259187A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US60186884A 1984-04-19 1984-04-19
US601868 1984-04-19
US704593 1985-02-22

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2276605A Division JPH03151873A (ja) 1984-04-19 1990-10-17 プラスミノゲン活性化因子産生細胞系

Publications (2)

Publication Number Publication Date
JPS60259187A JPS60259187A (ja) 1985-12-21
JPH0358270B2 true JPH0358270B2 (enrdf_load_html_response) 1991-09-04

Family

ID=24409076

Family Applications (1)

Application Number Title Priority Date Filing Date
JP60081493A Granted JPS60259187A (ja) 1984-04-19 1985-04-18 プラスミノーゲン活性化因子を増収する方法

Country Status (1)

Country Link
JP (1) JPS60259187A (enrdf_load_html_response)

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL8003402A (nl) * 1980-06-11 1982-01-04 Leuven Res & Dev Vzw Nieuwe plasminogeen-activator en farmaceutisch preparaat met trombolytische werking.
IL63317A (en) * 1981-07-15 1985-05-31 Yeda Res & Dev Production of plasminogen activator
JPS59134733A (ja) * 1983-01-24 1984-08-02 Asahi Chem Ind Co Ltd 生物活性物質の製法

Also Published As

Publication number Publication date
JPS60259187A (ja) 1985-12-21

Similar Documents

Publication Publication Date Title
JP2534020B2 (ja) 血清不含培地による組織プラスミノ―ゲン活性化物質の製造方法
Pearistein et al. Surface proteins and fibrinolytic activity of cultured mammalian cells
Åstedt et al. The placental type plasminogen activator inhibitor, PAI 2
Sawaya et al. Biological significance of tissue plasminogen activator content in brain tumors
EP0158958B1 (en) Method and cell line for obtaining plasminogen activators
US4661453A (en) Production of tissue plasminogen activator factor
US4780412A (en) Fibrinolytic enzymes produced from established non-cancerous cell lines
Corti et al. Purification and characterization of single-chain urokinase-type plasminogen activator (pro-urokinase) from human A431 cells
US4851346A (en) Chemically defined growth medium
JPH0358270B2 (enrdf_load_html_response)
US5151359A (en) Method for producing of human tissue type plasminogen activator
CA1267621A (en) Method and cell line for obtaining plasminogen activators
Christman et al. Specificity of response in hamster cells induced to produce plasminogen activator by the tumor promoter, 12-O-tetradecanoylphorbol-13-acetate
CA1275062A (en) Plasminogen activator kym
Kunamneni et al. Urokinase-A strong plasminogen activator
CN85107267A (zh) 制备茗萘酊的方法及其应用
JP2879906B2 (ja) プロコラゲナーゼの製造方法
Urade et al. Continuous culture of human melanoma cells in protein-free medium: establishment and partial characterization
Kos et al. Reversal of human myeloid leukemia cells into normal granulocytes and macrophages: activity and intracellular distribution of catalase
JP2620299B2 (ja) 新規プロテアーゼ及び該プロテアーゼ産生細胞株
三木瑞枝 et al. Production of Human Type Glycosylated Tissue Plasminogen Activator and the Role of Its Carbohydrate Moiety
EP0227102A2 (en) Cell line established from human normal uterine muscle, method for producing plasminogen activator using the cell line, and plasminogen activator
JPS62205784A (ja) 新しい型のプラスミノ−ゲン活性化因子の製造方法
Heussen Characterization of a plasminogen activator from human melanoma cells cultured in vitro
JPS62158220A (ja) 変異株ｋｙｍ−ｅ