JPH0354306B2 - - Google Patents
Info
- Publication number
- JPH0354306B2 JPH0354306B2 JP59036365A JP3636584A JPH0354306B2 JP H0354306 B2 JPH0354306 B2 JP H0354306B2 JP 59036365 A JP59036365 A JP 59036365A JP 3636584 A JP3636584 A JP 3636584A JP H0354306 B2 JPH0354306 B2 JP H0354306B2
- Authority
- JP
- Japan
- Prior art keywords
- wipe
- indicator
- area
- occult blood
- sampling
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 238000012360 testing method Methods 0.000 claims description 65
- 239000008280 blood Substances 0.000 claims description 49
- 210000004369 blood Anatomy 0.000 claims description 49
- 230000000694 effects Effects 0.000 claims description 32
- 238000001514 detection method Methods 0.000 claims description 27
- 239000012530 fluid Substances 0.000 claims description 21
- 239000000463 material Substances 0.000 claims description 21
- 239000003153 chemical reaction reagent Substances 0.000 claims description 20
- 238000005070 sampling Methods 0.000 claims description 18
- 239000000758 substrate Substances 0.000 claims description 16
- BMUDPLZKKRQECS-UHFFFAOYSA-K 3-[18-(2-carboxyethyl)-8,13-bis(ethenyl)-3,7,12,17-tetramethylporphyrin-21,24-diid-2-yl]propanoic acid iron(3+) hydroxide Chemical compound [OH-].[Fe+3].[N-]1C2=C(C)C(CCC(O)=O)=C1C=C([N-]1)C(CCC(O)=O)=C(C)C1=CC(C(C)=C1C=C)=NC1=CC(C(C)=C1C=C)=NC1=C2 BMUDPLZKKRQECS-UHFFFAOYSA-K 0.000 claims description 9
- 229940109738 hematin Drugs 0.000 claims description 9
- 239000000853 adhesive Substances 0.000 claims description 3
- 230000001070 adhesive effect Effects 0.000 claims description 3
- 239000012620 biological material Substances 0.000 claims description 3
- 238000002788 crimping Methods 0.000 claims description 2
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 238000002386 leaching Methods 0.000 claims 1
- 239000000123 paper Substances 0.000 description 35
- 239000000243 solution Substances 0.000 description 34
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 16
- 230000002550 fecal effect Effects 0.000 description 16
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 13
- 238000004040 coloring Methods 0.000 description 12
- 238000006243 chemical reaction Methods 0.000 description 11
- 230000007935 neutral effect Effects 0.000 description 10
- 102000001554 Hemoglobins Human genes 0.000 description 7
- 108010054147 Hemoglobins Proteins 0.000 description 7
- 241000147041 Guaiacum officinale Species 0.000 description 6
- MHAJPDPJQMAIIY-UHFFFAOYSA-N Hydrogen peroxide Chemical compound OO MHAJPDPJQMAIIY-UHFFFAOYSA-N 0.000 description 6
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 6
- 210000003608 fece Anatomy 0.000 description 6
- 229940091561 guaiac Drugs 0.000 description 6
- 230000008859 change Effects 0.000 description 5
- 206010028980 Neoplasm Diseases 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 150000001875 compounds Chemical class 0.000 description 3
- 239000000356 contaminant Substances 0.000 description 3
- 102000003992 Peroxidases Human genes 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 239000002250 absorbent Substances 0.000 description 2
- 230000002745 absorbent Effects 0.000 description 2
- 230000004888 barrier function Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- BTIJJDXEELBZFS-QDUVMHSLSA-K hemin Chemical compound CC1=C(CCC(O)=O)C(C=C2C(CCC(O)=O)=C(C)\C(N2[Fe](Cl)N23)=C\4)=N\C1=C/C2=C(C)C(C=C)=C3\C=C/1C(C)=C(C=C)C/4=N\1 BTIJJDXEELBZFS-QDUVMHSLSA-K 0.000 description 2
- 229940025294 hemin Drugs 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 238000012986 modification Methods 0.000 description 2
- 230000004048 modification Effects 0.000 description 2
- 239000007800 oxidant agent Substances 0.000 description 2
- 108040007629 peroxidase activity proteins Proteins 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- 208000010676 Abnormality of the gastrointestinal tract Diseases 0.000 description 1
- 229920000742 Cotton Polymers 0.000 description 1
- 208000012671 Gastrointestinal haemorrhages Diseases 0.000 description 1
- 241000190019 Guaiacum Species 0.000 description 1
- 235000004440 Guaiacum sanctum Nutrition 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000002585 base Substances 0.000 description 1
- 239000003637 basic solution Substances 0.000 description 1
- 239000000872 buffer Substances 0.000 description 1
- 239000007979 citrate buffer Substances 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 239000003086 colorant Substances 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 238000000354 decomposition reaction Methods 0.000 description 1
- 230000013872 defecation Effects 0.000 description 1
- 239000002612 dispersion medium Substances 0.000 description 1
- 238000001704 evaporation Methods 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 239000004744 fabric Substances 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000011087 paperboard Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 238000010079 rubber tapping Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 241000894007 species Species 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000010186 staining Methods 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000010998 test method Methods 0.000 description 1
- 238000012795 verification Methods 0.000 description 1
- 230000000007 visual effect Effects 0.000 description 1
- 238000009736 wetting Methods 0.000 description 1
- 239000002023 wood Substances 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R15/00—Details of measuring arrangements of the types provided for in groups G01R17/00 - G01R29/00, G01R33/00 - G01R33/26 or G01R35/00
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/72—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving blood pigments, e.g. haemoglobin, bilirubin or other porphyrins; involving occult blood
- G01N33/721—Haemoglobin
- G01N33/726—Devices
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Hematology (AREA)
- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Urology & Nephrology (AREA)
- General Physics & Mathematics (AREA)
- Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Food Science & Technology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
- Sampling And Sample Adjustment (AREA)
- Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/491,008 US4578359A (en) | 1983-05-03 | 1983-05-03 | Occult-blood detection |
| US491008 | 1983-05-03 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59204765A JPS59204765A (ja) | 1984-11-20 |
| JPH0354306B2 true JPH0354306B2 (US08063081-20111122-C00115.png) | 1991-08-19 |
Family
ID=23950437
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP59036365A Granted JPS59204765A (ja) | 1983-05-03 | 1984-02-29 | 潜血検出用試料採取ワイプ |
Country Status (11)
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4937197A (en) * | 1984-12-11 | 1990-06-26 | Litmus Concepts, Inc. | Fecal occult blood test method |
| US4939097A (en) * | 1986-06-02 | 1990-07-03 | Litmus Concepts, Inc. | Fecal occult blood test methods |
| US4971914A (en) * | 1984-12-11 | 1990-11-20 | Litmus Concepts, Inc. | Developer for fecal occult blood tests |
| US5068197A (en) * | 1984-12-11 | 1991-11-26 | Litmus Concepts, Inc. | Fecal occult blood test methods |
| US4983416A (en) * | 1985-02-04 | 1991-01-08 | Propper Manufacturing Co., Inc. | Manufacturing method for an occult fecal blood test slide |
| US4808379A (en) * | 1985-02-08 | 1989-02-28 | Wardlaw Stephen C | Device for obtaining stool samples and detecting occult blood |
| US4804518A (en) * | 1985-02-25 | 1989-02-14 | Levine Robert A | Device for occult blood testing |
| US4675160A (en) * | 1986-01-28 | 1987-06-23 | Warner-Lambert Company | Occult blood test monitor |
| US5256372A (en) * | 1987-11-06 | 1993-10-26 | Idexx Corporation | Dipstick test device including a removable filter assembly |
| US5053342A (en) * | 1987-12-24 | 1991-10-01 | Litmus Concepts, Inc. | Fecal occult blood test reagents |
| US5182191A (en) * | 1988-10-14 | 1993-01-26 | Pacific Biotech, Inc. | Occult blood sampling device and assay |
| JPH02296152A (ja) * | 1989-05-11 | 1990-12-06 | Hidenobu Akutsu | 病状示唆検知用紙 |
| US5064766A (en) * | 1989-10-18 | 1991-11-12 | Wardlaw Stephen C | Method for differentiating the source of occult gastrointestinal bleeding |
| US5031619A (en) * | 1990-02-06 | 1991-07-16 | Exergen Corporation | Method for determining bleeding time |
| JP2611890B2 (ja) * | 1991-07-19 | 1997-05-21 | 富士写真フイルム株式会社 | 乾式分析要素を用いた測定方法及び乾式分析要素 |
| US6342037B1 (en) | 1998-06-29 | 2002-01-29 | The Procter & Gamble Company | Device having fecal component sensor |
| GB2382649A (en) * | 2000-12-13 | 2003-06-04 | Douglas Thomas Thomson | Toilet tissue for detecting occult blood |
| US7531319B2 (en) * | 2006-08-31 | 2009-05-12 | Kimberly-Clark Worldwide, Inc. | Array for rapid detection of a microorganism |
| US7763442B2 (en) * | 2006-08-31 | 2010-07-27 | Kimberly-Clark Worldwide, Inc. | Method for detecting candida on skin |
| CA2819862A1 (en) | 2010-12-10 | 2012-06-14 | H.B. Fuller Company | Flushable article including polyurethane binder and method of using the same |
| GB201107466D0 (en) | 2011-05-05 | 2011-06-15 | Loktionov Alexandre | Device and method for non-invasive collection of colorectal mucocellular layer and disease detection |
| US9091682B1 (en) | 2014-05-01 | 2015-07-28 | Steven M Hacker | Tissue specimen bottle with color indicator in lid verifying and confirming presence of human tissue or blood contained in specimen bottle |
| CN205548432U (zh) * | 2016-03-19 | 2016-09-07 | 深圳市兼明科技有限公司 | 用于辅助检测细菌感染的面巾纸 |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA901754A (en) * | 1972-06-06 | M. Larson Phyllis | Flushable moisture-retaining sanitary pad | |
| GB1018563A (en) * | 1963-01-23 | 1966-01-26 | John Church Wilkinson | Improvements in diagnostic aids |
| US3718431A (en) * | 1971-02-01 | 1973-02-27 | J Wild | Method of stool sample collection and testing apparatus therefor |
| US4005984A (en) * | 1975-05-16 | 1977-02-01 | Reese Fell Alsop | Diagnostic composition and method of using the same |
| US4082886A (en) * | 1977-08-15 | 1978-04-04 | Johnson & Johnson | Liquid absorbent fibrous material and method of making the same |
| US4175923A (en) * | 1978-06-26 | 1979-11-27 | Friend William G | Method and apparatus for occult blood testing in the home |
| US4259964A (en) * | 1979-07-09 | 1981-04-07 | Levine Robert A | Device for obtaining stool samples |
| US4273741A (en) * | 1979-07-09 | 1981-06-16 | Levine Robert A | Device for obtaining stool samples |
| US4420353A (en) * | 1980-01-07 | 1983-12-13 | Levine Robert A | Method of making a stool sampling device |
| US4333734A (en) * | 1980-01-18 | 1982-06-08 | Sloan-Kettering Institute For Cancer Research | Diagnostic device for fecal occult blood and method of use |
| US4365970A (en) * | 1981-05-01 | 1982-12-28 | Smithkline Instruments, Inc. | Specimen test slide and method for testing occult blood |
| US4473079A (en) * | 1982-09-13 | 1984-09-25 | Jasper David A | Simple, small, self-contained tests for occult blood |
| CA1216215A (en) * | 1983-03-01 | 1987-01-06 | Henry J. Wells | Peroxidase activity detection composition |
-
1983
- 1983-05-03 US US06/491,008 patent/US4578359A/en not_active Expired - Fee Related
-
1984
- 1984-02-14 ZA ZA841080A patent/ZA841080B/xx unknown
- 1984-02-14 CA CA000447381A patent/CA1214093A/en not_active Expired
- 1984-02-17 AU AU24708/84A patent/AU547840B2/en not_active Ceased
- 1984-02-24 DE DE8484301217T patent/DE3482624D1/de not_active Expired - Fee Related
- 1984-02-24 EP EP84301217A patent/EP0124214B1/en not_active Expired - Lifetime
- 1984-02-28 BR BR8400934A patent/BR8400934A/pt unknown
- 1984-02-29 JP JP59036365A patent/JPS59204765A/ja active Granted
- 1984-02-29 AR AR295872A patent/AR240366A1/es active
- 1984-02-29 KR KR1019840001020A patent/KR870001327B1/ko not_active IP Right Cessation
- 1984-02-29 NO NO840769A patent/NO164203C/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| JPS59204765A (ja) | 1984-11-20 |
| AU547840B2 (en) | 1985-11-07 |
| US4578359A (en) | 1986-03-25 |
| DE3482624D1 (de) | 1990-08-09 |
| AR240366A1 (es) | 1990-03-30 |
| AU2470884A (en) | 1984-11-08 |
| NO840769L (no) | 1984-11-05 |
| EP0124214A3 (en) | 1986-12-17 |
| EP0124214B1 (en) | 1990-07-04 |
| KR870001327B1 (ko) | 1987-07-13 |
| NO164203C (no) | 1990-09-05 |
| BR8400934A (pt) | 1985-03-05 |
| CA1214093A (en) | 1986-11-18 |
| NO164203B (no) | 1990-05-28 |
| ZA841080B (en) | 1984-09-26 |
| EP0124214A2 (en) | 1984-11-07 |
| KR850000073A (ko) | 1985-02-25 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4578358A (en) | Collection of specimens and detection of occult blood therein | |
| JPH0354306B2 (US08063081-20111122-C00115.png) | ||
| US5182191A (en) | Occult blood sampling device and assay | |
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