JPH0344051B2 - - Google Patents

Info

Publication number
JPH0344051B2
JPH0344051B2 JP58016860A JP1686083A JPH0344051B2 JP H0344051 B2 JPH0344051 B2 JP H0344051B2 JP 58016860 A JP58016860 A JP 58016860A JP 1686083 A JP1686083 A JP 1686083A JP H0344051 B2 JPH0344051 B2 JP H0344051B2
Authority
JP
Japan
Prior art keywords
formula
group
brain function
drug
stimulating
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
JP58016860A
Other languages
English (en)
Japanese (ja)
Other versions
JPS58146508A (ja
Inventor
Purateru Arain
Rakoo Arain
Buryugerii Giii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Synthelabo SA
Original Assignee
Delalande SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Delalande SA filed Critical Delalande SA
Publication of JPS58146508A publication Critical patent/JPS58146508A/ja
Publication of JPH0344051B2 publication Critical patent/JPH0344051B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP58016860A 1982-02-04 1983-02-03 （１−シンナモイル又は１−フエネチルカルボニル）ピペラジン誘導体を含有する神経系用薬剤 Granted JPS58146508A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IT19457/82A IT1151104B (it) 1982-02-04 1982-02-04 Impiego terapeutico di derivati (1-cinnamoil oppure 1-fenetil-carbonil)piperazinici
IT19457A/82 1982-02-04

Publications (2)

Publication Number Publication Date
JPS58146508A JPS58146508A (ja) 1983-09-01
JPH0344051B2 true JPH0344051B2 (enExample) 1991-07-04

Family

ID=11158179

Family Applications (1)

Application Number Title Priority Date Filing Date
JP58016860A Granted JPS58146508A (ja) 1982-02-04 1983-02-03 （１−シンナモイル又は１−フエネチルカルボニル）ピペラジン誘導体を含有する神経系用薬剤

Country Status (4)

Country Link
US (1) US4500531A (enExample)
JP (1) JPS58146508A (enExample)
FR (1) FR2520618A1 (enExample)
IT (1) IT1151104B (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2552762B1 (fr) * 1983-09-30 1986-07-25 Delalande Sa Nouveaux amides piperaziniques et homopiperaziniques derives de l'acide 3,4-dioxymethylene cinnamique, leur procede de preparation et leur application en therapeutique
JPS6172773A (ja) * 1984-09-17 1986-04-14 Terumo Corp ピペラジン誘導体およびこれを含有する血管拡張剤
JP2787628B2 (ja) * 1992-01-21 1998-08-20 富士写真フイルム株式会社 ハロゲン化銀写真感光材料
CA2514574A1 (en) * 2003-01-30 2004-08-12 Dynogen Pharmaceuticals, Inc. Use of sodium channel modulators for treating gastrointestinal tract disorders
CN101591310B (zh) * 2008-12-19 2012-03-21 王绍杰 一种马来酸桂哌齐特的制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1218591A (en) * 1968-04-03 1971-01-06 Delalande Sa Derivatives of n-(3,4,5-trimethoxy cennamoyl) piperazine and their process of preparation
FR2325372A2 (fr) * 1975-09-29 1977-04-22 Delalande Sa Nouveaux derives de la n-(trimethoxy-3,4,5 cinaamoyl) piperazine, leur procede de preparation et leur application en therapeutique

Also Published As

Publication number Publication date
FR2520618A1 (fr) 1983-08-05
IT8219457A0 (it) 1982-02-04
IT1151104B (it) 1986-12-17
JPS58146508A (ja) 1983-09-01
US4500531A (en) 1985-02-19
FR2520618B1 (enExample) 1984-10-26

Similar Documents

Publication Publication Date Title
TW202311216A (zh) 作為醫藥活性化合物之間苯二酚衍生物及其製備方法
CS227019B2 (en) Method of preparing (-)-n-methyl-3-(2-methylphenyloxy)-3-phenylpropylamine
JPH0729922B2 (ja) ２‐アルコキシ‐ｎ‐（１‐アザビシクロ［２，２，２オクト‐３‐イル）ベンズアミド類およびチオベンズアミド類
JPS59205362A (ja) 新規ｎ−フエニル−ｎ′−シクロアルキルアルカノイル−ピペラジン、その製法、並びに該化合物を含有する鎮痛薬
JPH0641475B2 (ja) 置換アルファアミノ酸、その製法および医薬
JPH07509219A (ja) Ｈ↓３受容体アンタゴニストとしての４−［４’−ピペリジニルまたは３’−ピロリジニル］置換イミダゾールおよび治療上のその使用方法
EP0007206B1 (en) Phenethanolamines, their formulations, preparation and use
EP1098870B1 (en) Nitrate salt of Cetirizine
DE68917357T2 (de) Derivate der Coffeinsäure und pharmazeutische Zusammensetzungen, die sie enthalten.
US4599355A (en) Treatment of sleep disorders
JPH0681723B2 (ja) 非−白金抗癌薬によりひき起こされる嘔吐の軽減用治療剤
US3681346A (en) {60 -isomer of the decanoic acid ester of 10-{8 3,-(4-hydroxyethyl-1-piperazinyl)propylidene{9 -2-trifluoro-methyl thiaxanthene, acid addition salts thereof, method of use and compositions
US4877794A (en) 2-Alkoxy-n-(1-azabicyclo(2.2.2)oct-3-yl) benzamide and thiobenzamide compositions and the use thereof to treat schizophrenia
US3097136A (en) Process for producing a depressant-like effect on the central nervous system
JPS6230762A (ja) 新規５−オキソ−１−イミダゾリジンアセトアミド誘導体
CH637370A5 (en) Racemic forms and optically active forms of 2-(4-biphenylyl)-N-(diethylaminoalkyl)-propionamide, salts thereof and relative preparation processes
GB1571511A (en) Fused quinuclidine derivatives and pharmaceutical compositions containing them
JPS58146508A (ja) （１−シンナモイル又は１−フエネチルカルボニル）ピペラジン誘導体を含有する神経系用薬剤
JPS5935387B2 (ja) ３−アミノ−２−ヒドロキシプロパンのジ−置換フエノ−ルエ−テル類、その製法ならびに医薬用途
US3682973A (en) Benzodioxole compounds of therapeutic interest
CN1019577B (zh) 6-氯-4-羟基-2-甲基-N-(2-吡啶基)-2H-噻吩并(2，3-e)-1，2-噻嗪-3-羧基酰胺1，1-二氧化物烯醇醚类化合物制备方法
US3148188A (en) Benzothiazine derivatives
US4021560A (en) 2-[(Dimethylamino)(3-pyridyl)methyl]cyclohexanol and related compounds
US3718694A (en) N-ARYLACYLAMINO-ALKYL-{11 AND-ALKYLIDENE-DIBENZO {8 a,d{9 CYCLOHEPTENES AND-ANTHRACENES AND THE SALTS THEREOF
US4185124A (en) 2-(4-Biphenylyl)-N-(2-diethylamino alkyl)propionamide and salts thereof used as spasmolytic agents