JPH0259956B2 - - Google Patents
Info
- Publication number
- JPH0259956B2 JPH0259956B2 JP58001329A JP132983A JPH0259956B2 JP H0259956 B2 JPH0259956 B2 JP H0259956B2 JP 58001329 A JP58001329 A JP 58001329A JP 132983 A JP132983 A JP 132983A JP H0259956 B2 JPH0259956 B2 JP H0259956B2
- Authority
- JP
- Japan
- Prior art keywords
- signal processing
- specific cleavage
- autoradiograph
- sampling
- phosphor sheet
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000126 substance Substances 0.000 claims description 97
- 238000005070 sampling Methods 0.000 claims description 81
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 78
- 238000003776 cleavage reaction Methods 0.000 claims description 74
- 230000007017 scission Effects 0.000 claims description 74
- 238000012545 processing Methods 0.000 claims description 64
- 238000003672 processing method Methods 0.000 claims description 33
- 238000000034 method Methods 0.000 claims description 32
- 238000000376 autoradiography Methods 0.000 claims description 31
- 238000000926 separation method Methods 0.000 claims description 29
- 238000000354 decomposition reaction Methods 0.000 claims description 24
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 claims description 24
- 238000011161 development Methods 0.000 claims description 23
- OPTASPLRGRRNAP-UHFFFAOYSA-N cytosine Chemical compound NC=1C=CNC(=O)N=1 OPTASPLRGRRNAP-UHFFFAOYSA-N 0.000 claims description 22
- 230000005855 radiation Effects 0.000 claims description 20
- 238000009499 grossing Methods 0.000 claims description 18
- RWQNBRDOKXIBIV-UHFFFAOYSA-N thymine Chemical compound CC1=CNC(=O)NC1=O RWQNBRDOKXIBIV-UHFFFAOYSA-N 0.000 claims description 18
- 239000000203 mixture Substances 0.000 claims description 12
- 229940104302 cytosine Drugs 0.000 claims description 11
- 230000002285 radioactive effect Effects 0.000 claims description 10
- GFFGJBXGBJISGV-UHFFFAOYSA-N Adenine Chemical compound NC1=NC=NC2=C1N=CN2 GFFGJBXGBJISGV-UHFFFAOYSA-N 0.000 claims description 9
- 229930024421 Adenine Natural products 0.000 claims description 9
- 229960000643 adenine Drugs 0.000 claims description 9
- 229920001222 biopolymer Polymers 0.000 claims description 9
- 229940113082 thymine Drugs 0.000 claims description 9
- 102000039446 nucleic acids Human genes 0.000 claims description 6
- 108020004707 nucleic acids Proteins 0.000 claims description 6
- 150000007523 nucleic acids Chemical class 0.000 claims description 6
- 239000000463 material Substances 0.000 claims description 4
- 230000008569 process Effects 0.000 claims description 3
- 238000002601 radiography Methods 0.000 claims description 2
- 239000000047 product Substances 0.000 claims 32
- 230000015556 catabolic process Effects 0.000 claims 2
- 239000007857 degradation product Substances 0.000 claims 2
- 238000006731 degradation reaction Methods 0.000 claims 2
- 238000007619 statistical method Methods 0.000 claims 1
- 238000004020 luminiscence type Methods 0.000 description 13
- 230000006870 function Effects 0.000 description 10
- 238000013508 migration Methods 0.000 description 9
- 230000005012 migration Effects 0.000 description 9
- 238000009826 distribution Methods 0.000 description 7
- 238000001962 electrophoresis Methods 0.000 description 7
- 238000010586 diagram Methods 0.000 description 6
- 238000006243 chemical reaction Methods 0.000 description 5
- 230000003287 optical effect Effects 0.000 description 5
- 239000000470 constituent Substances 0.000 description 4
- 230000005284 excitation Effects 0.000 description 4
- 238000012163 sequencing technique Methods 0.000 description 4
- -1 europium-activated barium fluoride bromide Chemical class 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 229910052693 Europium Inorganic materials 0.000 description 2
- 230000003321 amplification Effects 0.000 description 2
- 238000003491 array Methods 0.000 description 2
- 238000009125 cardiac resynchronization therapy Methods 0.000 description 2
- 238000005520 cutting process Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 230000001747 exhibiting effect Effects 0.000 description 2
- 229910052739 hydrogen Inorganic materials 0.000 description 2
- 239000001257 hydrogen Substances 0.000 description 2
- 239000012535 impurity Substances 0.000 description 2
- 239000003550 marker Substances 0.000 description 2
- 238000003199 nucleic acid amplification method Methods 0.000 description 2
- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 230000001681 protective effect Effects 0.000 description 2
- 239000000941 radioactive substance Substances 0.000 description 2
- WHBHBVVOGNECLV-OBQKJFGGSA-N 11-deoxycortisol Chemical compound O=C1CC[C@]2(C)[C@H]3CC[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 WHBHBVVOGNECLV-OBQKJFGGSA-N 0.000 description 1
- QTBSBXVTEAMEQO-UHFFFAOYSA-M Acetate Chemical compound CC([O-])=O QTBSBXVTEAMEQO-UHFFFAOYSA-M 0.000 description 1
- 239000000020 Nitrocellulose Substances 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- NIXOWILDQLNWCW-UHFFFAOYSA-N acrylic acid group Chemical group C(C=C)(=O)O NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 description 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 description 1
- 150000001342 alkaline earth metals Chemical class 0.000 description 1
- 238000004458 analytical method Methods 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 230000003247 decreasing effect Effects 0.000 description 1
- OGPBJKLSAFTDLK-UHFFFAOYSA-N europium atom Chemical compound [Eu] OGPBJKLSAFTDLK-UHFFFAOYSA-N 0.000 description 1
- 239000000499 gel Substances 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 230000010365 information processing Effects 0.000 description 1
- 229920002521 macromolecule Polymers 0.000 description 1
- 238000000465 moulding Methods 0.000 description 1
- 229920001220 nitrocellulos Polymers 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- 229910052698 phosphorus Inorganic materials 0.000 description 1
- 239000011574 phosphorus Substances 0.000 description 1
- 229920000728 polyester Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 239000013558 reference substance Substances 0.000 description 1
- 229920005989 resin Polymers 0.000 description 1
- 239000011347 resin Substances 0.000 description 1
- 230000004044 response Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 239000000741 silica gel Substances 0.000 description 1
- 229910002027 silica gel Inorganic materials 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
- 230000002194 synthesizing effect Effects 0.000 description 1
- 229920003002 synthetic resin Polymers 0.000 description 1
- 239000000057 synthetic resin Substances 0.000 description 1
- 239000013076 target substance Substances 0.000 description 1
- 238000004809 thin layer chromatography Methods 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 229920006352 transparent thermoplastic Polymers 0.000 description 1
Landscapes
- Investigating Or Analysing Biological Materials (AREA)
- Measurement Of Radiation (AREA)
- Radiography Using Non-Light Waves (AREA)
Priority Applications (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58001329A JPS59126530A (ja) | 1983-01-08 | 1983-01-08 | オ−トラジオグラフイ−における信号処理方法 |
| EP84100150A EP0113677A3 (de) | 1983-01-08 | 1984-01-09 | Signalbearbeitungsmethode in der Autoradiographie |
| US06/883,922 US4837733A (en) | 1983-01-08 | 1986-07-10 | Signal processing method in autoradiography |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58001329A JPS59126530A (ja) | 1983-01-08 | 1983-01-08 | オ−トラジオグラフイ−における信号処理方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS59126530A JPS59126530A (ja) | 1984-07-21 |
| JPH0259956B2 true JPH0259956B2 (de) | 1990-12-13 |
Family
ID=11498455
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP58001329A Granted JPS59126530A (ja) | 1983-01-08 | 1983-01-08 | オ−トラジオグラフイ−における信号処理方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS59126530A (de) |
-
1983
- 1983-01-08 JP JP58001329A patent/JPS59126530A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS59126530A (ja) | 1984-07-21 |
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