JPH0231687B2 - - Google Patents

Description

[Detailed description of the invention]

The present invention uses an oily substance, water, and
This is an emulsified cosmetic for skin or hair that contains an emulsifier, a water-soluble polymer, and stevioside as an emulsification aid. Stevioside is
Stevia rebaugiana bertoni is a perennial medicinal plant of the Chrysanthemum family that grows wild in Paraguay, South America.
Rebaudiana Bertoni) is a substance that is approximately 300 times sweeter than sucrose extracted from the leaves of Rebaudiana Bertoni.
It is also used as a medicinal sweetener for diabetics. Its structure is a diterpene glycoside (A) consisting of a diterpene named steviol, sophorose (2-O-β-D-glucopyranosyl-β-D-glucopyranose) and β-D-glucopyranose. Structural formula of stevioside Synthetic surfactants conventionally used as emulsifiers and solubilizers have problems such as irritation to the skin, and attempts have been made to replace them with surfactant substances that are highly safe or their derivatives. In the present invention, it has been found that the above-mentioned stevioside is extremely effective in emulsified cosmetics for the skin or hair such as creams and emulsions, or as an emulsification aid. That is, the emulsifying power of stevioside alone is very weak, but when used in combination with glycerin monofatty acid ester, which is a surfactant, the emulsifying power is significantly improved, leading to the present invention.
If there is a large amount of oily substances, adding xanthan gum, which is a water-soluble polymer (particularly a natural surfactant) and has a thickening effect, will result in a cosmetic with high emulsion stability. In addition, as in the case of glycyrrhizic acid derivatives, when water-soluble polysaccharides such as pectin are used in combination, emulsion stability improves, but foaming properties also increase and defoaming during manufacturing (emulsification) becomes a problem, leading to mass production. However, when using stevioside in the present invention, one of the characteristics is that such foaming does not occur. Another major feature is that it does not cause any problems. The purpose of the present invention is to have high safety for the skin;
An object of the present invention is to provide an emulsified cosmetic that has excellent emulsion stability and storage stability, and has a good feel when used. Another object of the present invention is to provide a novel emulsifier composition. That is, the present invention is an emulsified cosmetic for skin or hair that contains stevioside, glycerin monofatty acid ester, water-soluble polymer (particularly natural surfactant), oily substance, and water as main components. The stevioside used in the present invention may be a commercially available one, or stevioside increased in volume with lactic acid, dextrin, etc. may be used. The amount of stevioside used is usually 0.01 to 5.0% by weight, preferably 0.02 to 2.0% by weight. If it is less than 0.01% by weight, the emulsion stability will be poor and the effect of adding stevioside will hardly be obtained, so it is not suitable for the present invention. It is also possible to incorporate 5.0% by weight or more, but this is not preferred in the present invention because depending on the emulsifying system, the emulsified particles may become larger and tend to gel. Examples of the glycerin monofatty acid ester used in the present invention include glycerin monostearate and glycerin monopalmitate. The amount used is 0.1-10.0% by weight, preferably 0.5-5.0% by weight. If it is less than 0.1% by weight, the emulsion stability will be poor, and if it is more than 10% by weight, the emulsion system will become hard over time, which is not suitable for the present invention.
In the present invention, in order to clearly see the effect of stevioside, we investigated the use of stevioside in combination with glycerin monofatty acid ester, which has a relatively weak emulsifying power and is highly safe against skin irritation, etc., but the existing emulsifying power It is also possible to combine or replace strong synthetic or natural surfactants. The oily substance used in the present invention may be any known oily substance for skin cosmetics, including hydrocarbons such as squalane and liquid paraffin, higher alcohols such as cetyl alcohol and stearyl alcohol, stearic acid, and behenic acid. In addition to higher fatty acids such as ester oils such as octyldodecyl myristate, animal and vegetable fats and oils, waxes, silicone oils, and the like. These oily substances are used alone or in combination of two or more, and the amount used is 10~
80% by weight, preferably 20-70% by weight. If it is less than 10% by weight, the emulsion stability will be poor, and if it is more than 80% by weight, it will become extremely sticky, which is not suitable for the present invention. Then the amount of water used is 10-90% by weight, preferably
20-80% by weight. Stevioside that can be used in the present invention exhibits good surfactant ability regardless of PH conditions, etc., but when a large amount of oily substances is blended, By blending natural surfactants and bentonite, oily substances can be emulsified extremely stably. These can be used alone or in combination of two or more, and the blending amount is 0.01 to 8.0% by weight, preferably 0.1 to 3.0% by weight. Furthermore, it is also possible to add cosmetic medicinal ingredients, humectants, preservatives, fragrances, colorants, pigments, etc., as necessary. The emulsified cosmetic composition of the present invention is produced by a known production method, such as dissolving water and stevioside by heating and stirring, and then adding the mixture to a heated and molten oily substance, mixing and emulsifying with stirring. The emulsified cosmetics for skin or hair of the present invention are applicable to skin, hair, and whole body emulsified cosmetics such as skin creams, pine surge creams, cleansing creams, milky lotions, foundation creams, hair creams, and body creams. be done. Furthermore, since stevioside is considered to be a sweetener with emulsifying power, it can be fully expected to be applied to foods and the like. The emulsified cosmetic composition of the present invention is highly safe for the skin, has good feel and appearance, and has excellent emulsion stability and stability over time, and has extremely high product value. This will be explained below with reference to examples. The amounts shown in Examples are parts by weight. Example 1 Emulsion A Formula Amount 1 Squalane 20.0 parts 2 Octyldodecyl myristate 1.5 3 Cetyl alcohol 2.0 4 Glycerin monostearate 2.0 5 Stevioside 0.5 6 Xanthan gum 0.3 7 Methylparaben 0.1 8 Purified water 33.5 9 Fragrance 0.1 B Manufacturing method; oil Components ~ and water-soluble components ~ are each heated to 75 to 80°C to uniformly dissolve them. Next, while stirring the oil component using a homomixer, a water-soluble component is added and emulsified, followed by cooling. During cooling, the ingredients are added and mixed at 60°C, and the product is obtained by cooling to 30°C. The obtained emulsion is an o/w type emulsion that has good texture, texture, and gloss, and is extremely stable even after 3 months in a thermostat at 5 to 40°C, and has excellent fluidity. Ta. Example 2 In order to examine the effects of the present invention, various emulsions were produced in the same manner as in Example 1. Their prescriptions are shown in Table 1.
Further, the results are summarized in Table 2. In addition, prescription 1,
2 and 3 are comparative examples.

【table】

【table】

[Table] As is clear from Table 2, the effect of the addition of stevioside is remarkable. If glycerin monostearate or stevioside is omitted from the formulation, it will hardly emulsify. The combined use of glycerin monostearate and stevioside improves the emulsification state, and addition of xanthan gum, a natural surfactant, increases stability over time. or,
When cetanol (sample 7), which has surfactant properties, stearic acid, lecithin, cholesterol, etc. are further added, a milky lotion with good stability over time and an extremely good texture can be obtained. On the other hand, the amount of stevioside used is
If the amount is less than 0.01% by weight, the stability over time will be poor, but if the amount is more than 0.01% by weight, the emulsion particles will be made uniform and fine, resulting in an emulsion with good emulsion stability.
When the amount of stevioside used is 2.0% by weight or more,
It becomes a little gel-like and the emulsified particles also become larger, so there is a tendency for the feeling of use to be poor. Example 3 Pine surge cream A Formulation 1 Liquid paraffin 50.0 parts 2 Cetyl alcohol 2.0 3 Glycerin monostearate 2.0 4 Cholesterol 0.5 5 Stevioside 0.5 6 Xanthan gum 0.3 7 Methylparaben 0.2 8 Purified water 33.0 9 Fragrance Appropriate amount B Manufacturing method; Same as Example 1 I did it. The obtained pine surge cream is an O/W type emulsion, has good appearance such as texture and gloss, and has a rating of 5~
It remained extremely stable even after being stored for 3 months in a 40°C constant temperature bath. Example 4 Skin cream A Formulation 1 Liquid paraffin 20.0 parts 2 Squalane 5.0 3 Octyldodecyl myristate 5.0 4 Glycerin monostearate 2.5 5 Cetyl alcohol 2.0 6 Stevioside 0.8 7 Xanthan gum 0.3 8 1,3-butylene glycol 5.0 9 Methylparaben 0.2 10 Purified water 59.1 11 Perfumery 0.1 B Manufacturing method: Produced according to Example 1. The obtained skin cream was an O/W type emulsion, had good feel and appearance, and remained stable even after 3 months in a thermostat at 5 to 40°C. Example 5 Foundation cream 1 Squalane 5.0 parts 2 Liquid paraffin 15.0 3 Glycerin monostearate 2.5 4 Cetyl alcohol 1.0 5 Butylparaben 0.2 6 Stevioside 0.5 7 Xanthan gum 0.3 8 Bentonite 0.5 9 Pigment 6.0 10 Purified water 68.9 11 Fragrance 0. 1B Manufacturing Method: After dispersing the pigment in an aqueous phase, the same procedure as in Example 1 was followed. The obtained foundation cream is an O/W emulsion with an appearance,
The feeling of use was good, and it was stable even after 3 months in a constant temperature bath of 5 to 40°C, and no agglomeration or solidification of the pigment occurred. Stevioside used in the present invention has been evaluated to be extremely safe in safety tests (acute toxicity, mutagenicity, pregnancy suppression, subacute toxicity) conducted in Japan. In order to further clarify the safety of the cosmetic composition of the present invention, the following irritation test was conducted. Animal test (by Draize method) Test method: The hair on the back of Japanese white rabbits weighing 2.5 to 3.0 kg is clipped with clippers, and 5 rabbits with normal skin are fixed on a fixing table. Apply an appropriate amount of the test sample (sample of Example 1) to a 2 x 2 cm lint cloth adhesive plaster and apply it to the skin. After 24 hours, remove the lint cloth and check the skin reaction according to the criteria to determine erythema and edema. Observe about. Judgment will be made again after 72 hours, and 24 hours will be determined.
Judgment was made by taking the average over 72 hours. Judgment: (1) Formation of erythema and diseased skin Judgment values ●No noticeable erythema 0 ●Slight erythema 1 ●Clear erythema 2 ●Strong erythema 3 ● Strong erythema with a slight crust 4 (2) Formation of edema Judgment value●No edema observed 0●Very slight edema observed
1 ●Those with slight edema 2 ●Those with moderate edema (approximately 1 mm) 3 ●Those with strong edema (protruding outside the patch area) 4 Evaluation of test substance: Judgment numerical value Average sum 2 or less...Slight irritation or almost no irritation 2.1-5.0...Moderate irritation 5 or more...Strong irritation Human test (by human body closed patch test) Test method: Finch Yanbar (Taisho Pharmaceutical) A 48-hour occlusive patch is applied to the flexor side of the forearm. Judgments are made after 48 hours and 72 hours. However, if there is a strong reaction and itching occurs at the application site, discontinue application. Participants: 50 healthy people Judgment criteria: No change at all (-) Faint erythema (±) Obvious erythema (+) The stevioside composition shown in Example 1 was used as a test sample. The above test results indicate that the animal skin irritation score is 0.
The results of the human skin irritation test were all negative (-), confirming that each of the stevioside compositions of the present invention is highly safe.

Claims (1)

[Claims] 1. An emulsified cosmetic for skin or hair containing an oily substance, water, an emulsifier, a water-soluble polymer, and stevioside as an emulsification aid.