JPH0219092B2 - - Google Patents
Info
- Publication number
- JPH0219092B2 JPH0219092B2 JP57073731A JP7373182A JPH0219092B2 JP H0219092 B2 JPH0219092 B2 JP H0219092B2 JP 57073731 A JP57073731 A JP 57073731A JP 7373182 A JP7373182 A JP 7373182A JP H0219092 B2 JPH0219092 B2 JP H0219092B2
- Authority
- JP
- Japan
- Prior art keywords
- cyclodextrin
- polypeptide
- nasal
- acid
- administration
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 108090000765 processed proteins & peptides Proteins 0.000 claims description 36
- 102000004196 processed proteins & peptides Human genes 0.000 claims description 32
- 229920001184 polypeptide Polymers 0.000 claims description 29
- 229920000858 Cyclodextrin Polymers 0.000 claims description 25
- 238000002360 preparation method Methods 0.000 claims description 25
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- 239000000203 mixture Substances 0.000 description 15
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- 210000003928 nasal cavity Anatomy 0.000 description 12
- 229920001450 Alpha-Cyclodextrin Polymers 0.000 description 11
- HFHDHCJBZVLPGP-RWMJIURBSA-N alpha-cyclodextrin Chemical compound OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O[C@H]3O[C@H](CO)[C@H]([C@@H]([C@H]3O)O)O3)[C@H](O)[C@H]2O)CO)O[C@@H]1O[C@H]1[C@H](O)[C@@H](O)[C@@H]3O[C@@H]1CO HFHDHCJBZVLPGP-RWMJIURBSA-N 0.000 description 11
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- 239000004334 sorbic acid Substances 0.000 description 1
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- 239000003549 soybean oil Substances 0.000 description 1
- 235000012424 soybean oil Nutrition 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 230000000087 stabilizing effect Effects 0.000 description 1
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- 238000001356 surgical procedure Methods 0.000 description 1
- 229940095064 tartrate Drugs 0.000 description 1
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- 125000000999 tert-butyl group Chemical group [H]C([H])([H])C(*)(C([H])([H])[H])C([H])([H])[H] 0.000 description 1
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- 229960003726 vasopressin Drugs 0.000 description 1
- 238000005303 weighing Methods 0.000 description 1
- 229920001285 xanthan gum Polymers 0.000 description 1
- 235000010493 xanthan gum Nutrition 0.000 description 1
- 239000000230 xanthan gum Substances 0.000 description 1
- 229940082509 xanthan gum Drugs 0.000 description 1
Landscapes
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57073731A JPS58189118A (ja) | 1982-04-30 | 1982-04-30 | 経鼻投与製剤 |
| EP83302118A EP0094157B1 (fr) | 1982-04-30 | 1983-04-14 | Composition pharmaceutique et son application |
| DE8383302118T DE3372705D1 (en) | 1982-04-30 | 1983-04-14 | Pharmaceutical composition and its use |
| US06/487,836 US4659696A (en) | 1982-04-30 | 1983-04-22 | Pharmaceutical composition and its nasal or vaginal use |
| CA000427018A CA1218606A (fr) | 1982-04-30 | 1983-04-29 | Compose pharmaceutique a usage nasal ou vaginal |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57073731A JPS58189118A (ja) | 1982-04-30 | 1982-04-30 | 経鼻投与製剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS58189118A JPS58189118A (ja) | 1983-11-04 |
| JPH0219092B2 true JPH0219092B2 (fr) | 1990-04-27 |
Family
ID=13526667
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP57073731A Granted JPS58189118A (ja) | 1982-04-30 | 1982-04-30 | 経鼻投与製剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS58189118A (fr) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0545521U (ja) * | 1991-11-20 | 1993-06-18 | 日本精機株式会社 | 表示板の照明装置 |
| EP0709099A2 (fr) | 1994-09-28 | 1996-05-01 | Senju Pharmaceutical Co., Ltd. | Suspension aqueuse nasale comprenant cyclodextrine |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE897904A (fr) * | 1982-10-05 | 1984-04-04 | Sandoz Sa | Nouvelles compositions galeniques a base de calcitonine |
| JPS61194034A (ja) * | 1985-02-25 | 1986-08-28 | Teijin Ltd | 経鼻投与用粉末状組成物 |
| DK179286D0 (da) * | 1986-04-18 | 1986-04-18 | Nordisk Gentofte | Insulinpraeparat |
| GB8620035D0 (en) * | 1986-08-18 | 1986-10-01 | Sandoz Ltd | Organic compounds |
| ATE99543T1 (de) * | 1987-10-15 | 1994-01-15 | Syntex Inc | Pulverfoermige zubereitungen zur intranasalen verabreichung von polypeptiden. |
| JPH0341033A (ja) * | 1989-07-07 | 1991-02-21 | Kyowa Hakko Kogyo Co Ltd | 安定なモチリン類含有製剤 |
| JPH11292787A (ja) * | 1995-08-15 | 1999-10-26 | Asahi Chem Ind Co Ltd | 生理活性ペプチドを含有する経粘膜投与製剤 |
| PE20171334A1 (es) * | 2015-02-17 | 2017-09-13 | Lilly Co Eli | Formulacion en polvo nasal para el tratamiento de hipoglicemia |
-
1982
- 1982-04-30 JP JP57073731A patent/JPS58189118A/ja active Granted
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0545521U (ja) * | 1991-11-20 | 1993-06-18 | 日本精機株式会社 | 表示板の照明装置 |
| EP0709099A2 (fr) | 1994-09-28 | 1996-05-01 | Senju Pharmaceutical Co., Ltd. | Suspension aqueuse nasale comprenant cyclodextrine |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS58189118A (ja) | 1983-11-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| LAPS | Cancellation because of no payment of annual fees |