US4464467A
(en)
*
|
1982-07-26 |
1984-08-07 |
Bristol-Myers Company |
Antitumor antibiotics produced by new streptomyces
|
GB9818730D0
(en)
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collections of compounds
|
DK1109812T3
(da)
*
|
1998-08-27 |
2005-09-05 |
Spirogen Ltd |
Pyrrolobenzodiazepiner
|
GB9818732D0
(en)
*
|
1998-08-27 |
1998-10-21 |
Univ Portsmouth |
Collection of compounds
|
US6909006B1
(en)
|
1999-08-27 |
2005-06-21 |
Spirogen Limited |
Cyclopropylindole derivatives
|
GB0226593D0
(en)
|
2002-11-14 |
2002-12-24 |
Consultants Ltd |
Compounds
|
GB0321295D0
(en)
|
2003-09-11 |
2003-10-15 |
Spirogen Ltd |
Synthesis of protected pyrrolobenzodiazepines
|
GB0404577D0
(en)
|
2004-03-01 |
2004-04-07 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
ATE542821T1
(de)
|
2004-03-01 |
2012-02-15 |
Spirogen Ltd |
11-hydroxy-5h-pyrroloä2,1-cüä1,4übenzodiazepin- - on derivate als zwischenverbindungen für die herstellung von c2 substituierten pyrrolobenzodiazepinen
|
WO2005085260A1
(en)
|
2004-03-09 |
2005-09-15 |
Spirogen Limited |
Pyrrolobenzodiazepines
|
GB0819095D0
(en)
|
2008-10-17 |
2008-11-26 |
Spirogen Ltd |
Pyrrolobenzodiazepines
|
AU2015224492B2
(en)
*
|
2009-02-05 |
2017-04-20 |
Immunogen, Inc. |
Novel benzodiazepine derivatives
|
NZ594177A
(en)
|
2009-02-05 |
2014-02-28 |
Immunogen Inc |
Novel benzodiazepine derivatives
|
GB201006340D0
(en)
|
2010-04-15 |
2010-06-02 |
Spirogen Ltd |
Synthesis method and intermediates
|
CN102971329B
(zh)
|
2010-04-15 |
2016-06-29 |
麦迪穆有限责任公司 |
用于治疗增殖性疾病的吡咯并苯并二氮杂卓
|
US9242013B2
(en)
|
2010-04-15 |
2016-01-26 |
Seattle Genetics Inc. |
Targeted pyrrolobenzodiazapine conjugates
|
BR112013020540B1
(pt)
|
2011-02-15 |
2020-12-29 |
Immunogen, Inc |
métodos para preparação de conjugados compreendendo agente de ligação à célula conjugado a composto citotóxico com grupo ligante
|
AU2012322613B2
(en)
|
2011-10-14 |
2016-04-21 |
Medimmune Limited |
Pyrrolobenzodiazepines and targeted conjugates
|
EP3388435B1
(en)
|
2011-10-14 |
2023-05-03 |
Seagen Inc. |
Pyrrolobenzodiazepines and targeted conjugates
|
JP6166728B2
(ja)
|
2011-10-14 |
2017-07-19 |
メドイミューン・リミテッドMedImmune Limited |
ピロロベンゾジアゼピンの製造に有用な合成方法及び中間体
|
WO2014057120A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sàrl |
Pyrrolobenzodiazepine-antibody conjugates
|
BR112015008232A2
(pt)
|
2012-10-12 |
2017-12-05 |
Adc Therapeutics Sarl |
conjugados pirrolbenzodiazepina-anticorpo
|
WO2014057113A1
(en)
|
2012-10-12 |
2014-04-17 |
Adc Therapeutics Sarl |
Pyrrolobenzodiazepine - anti-psma antibody conjugates
|
HUE035694T2
(en)
|
2012-10-12 |
2018-05-28 |
Adc Therapeutics Sa |
Pirrolobenzodiazepine anti-CD22 antibody conjugates
|
EP2906249B1
(en)
|
2012-10-12 |
2018-06-27 |
MedImmune Limited |
Synthesis and intermediates of pyrrolobenzodiazepine derivatives for conjugation
|
ES2680153T3
(es)
|
2012-10-12 |
2018-09-04 |
Adc Therapeutics Sa |
Conjugados de anticuerpos anti-PSMA-pirrolobenzodiazepinas
|
BR112015008174B1
(pt)
|
2012-10-12 |
2022-12-27 |
Medimmune Limited |
Conjugados de pirrolobenzodiazepina-anticorpo, composição farmacêutica compreendendo ditos conjugados e usos dos mesmos para tratar doença proliferativa e cancêr
|
PL2839860T3
(pl)
|
2012-10-12 |
2019-10-31 |
Medimmune Ltd |
Pirolobenzodiazepiny i ich koniugaty
|
EP3054983B1
(en)
|
2013-10-11 |
2019-03-20 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
US9956299B2
(en)
|
2013-10-11 |
2018-05-01 |
Medimmune Limited |
Pyrrolobenzodiazepine—antibody conjugates
|
GB201317981D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
GB201317982D0
(en)
|
2013-10-11 |
2013-11-27 |
Spirogen Sarl |
Pyrrolobenzodiazepines and conjugates thereof
|
EP3054985B1
(en)
|
2013-10-11 |
2018-12-26 |
Medimmune Limited |
Pyrrolobenzodiazepine-antibody conjugates
|
GB201416112D0
(en)
|
2014-09-12 |
2014-10-29 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
EP3223854A1
(en)
|
2014-11-25 |
2017-10-04 |
ADC Therapeutics SA |
Pyrrolobenzodiazepine-antibody conjugates
|
GB201506402D0
(en)
|
2015-04-15 |
2015-05-27 |
Berkel Patricius H C Van And Howard Philip W |
Site-specific antibody-drug conjugates
|
GB201506411D0
(en)
|
2015-04-15 |
2015-05-27 |
Bergenbio As |
Humanized anti-axl antibodies
|
GB201601431D0
(en)
|
2016-01-26 |
2016-03-09 |
Medimmune Ltd |
Pyrrolobenzodiazepines
|
GB201602359D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201602356D0
(en)
|
2016-02-10 |
2016-03-23 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201607478D0
(en)
|
2016-04-29 |
2016-06-15 |
Medimmune Ltd |
Pyrrolobenzodiazepine Conjugates
|
GB201617466D0
(en)
|
2016-10-14 |
2016-11-30 |
Medimmune Ltd |
Pyrrolobenzodiazepine conjugates
|
GB201702031D0
(en)
|
2017-02-08 |
2017-03-22 |
Medlmmune Ltd |
Pyrrolobenzodiazepine-antibody conjugates
|
US11160872B2
(en)
|
2017-02-08 |
2021-11-02 |
Adc Therapeutics Sa |
Pyrrolobenzodiazepine-antibody conjugates
|
US11370801B2
(en)
|
2017-04-18 |
2022-06-28 |
Medimmune Limited |
Pyrrolobenzodiazepine conjugates
|
MX2019012464A
(es)
|
2017-04-20 |
2019-12-11 |
Adc Therapeutics Sa |
Terapia combinada con un conjugado de anticuerpo y farmaco anti-axl.
|
ES2988683T3
(es)
|
2017-06-14 |
2024-11-21 |
Adc Therapeutics Sa |
Pautas posológicas para la administración de un CAF anti-CD19
|
JP7220203B2
(ja)
|
2017-08-18 |
2023-02-09 |
メドイミューン・リミテッド |
ピロロベンゾジアゼピン複合体
|
IL301636B2
(en)
|
2017-09-29 |
2025-02-01 |
Daiichi Sankyo Co Ltd |
Conjugation of an antibody with a pyrrolobenzodiazepine derivative
|
GB201803342D0
(en)
|
2018-03-01 |
2018-04-18 |
Medimmune Ltd |
Methods
|
GB201806022D0
(en)
|
2018-04-12 |
2018-05-30 |
Medimmune Ltd |
Pyrrolobenzodiazepines and conjugates thereof
|
BR112021018260A2
(pt)
|
2019-03-15 |
2021-11-23 |
Medimmune Ltd |
Dímeros de azetidobenzodiazepina e conjugados compreendendo-os para uso no tratamento de câncer
|