JPH0156049B2 - - Google Patents
Info
- Publication number
- JPH0156049B2 JPH0156049B2 JP62142097A JP14209787A JPH0156049B2 JP H0156049 B2 JPH0156049 B2 JP H0156049B2 JP 62142097 A JP62142097 A JP 62142097A JP 14209787 A JP14209787 A JP 14209787A JP H0156049 B2 JPH0156049 B2 JP H0156049B2
- Authority
- JP
- Japan
- Prior art keywords
- ointment
- gentamicin
- insulin
- treatment
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims description 26
- 102000004877 Insulin Human genes 0.000 claims description 13
- 108090001061 Insulin Proteins 0.000 claims description 13
- 229940125396 insulin Drugs 0.000 claims description 13
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 claims description 12
- 229930182566 Gentamicin Natural products 0.000 claims description 12
- 206010052428 Wound Diseases 0.000 claims description 12
- 208000027418 Wounds and injury Diseases 0.000 claims description 12
- 229960002518 gentamicin Drugs 0.000 claims description 12
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 239000002674 ointment Substances 0.000 description 25
- 206010012601 diabetes mellitus Diseases 0.000 description 10
- 238000002360 preparation method Methods 0.000 description 9
- RDEIXVOBVLKYNT-VQBXQJRRSA-N (2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[(2r,3r,6s)-3-amino-6-(1-aminoethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;(2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[(2r,3r,6s)-3-amino-6-(aminomethyl)oxan-2-yl]o Chemical compound OS(O)(=O)=O.O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC[C@@H](CN)O2)N)[C@@H](N)C[C@H]1N.O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC[C@H](O2)C(C)N)N)[C@@H](N)C[C@H]1N.O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N RDEIXVOBVLKYNT-VQBXQJRRSA-N 0.000 description 5
- 239000003814 drug Substances 0.000 description 4
- 229940057995 liquid paraffin Drugs 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 229940124597 therapeutic agent Drugs 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 208000025865 Ulcer Diseases 0.000 description 3
- 230000035876 healing Effects 0.000 description 3
- 239000000203 mixture Substances 0.000 description 3
- 235000019271 petrolatum Nutrition 0.000 description 3
- 231100000397 ulcer Toxicity 0.000 description 3
- 239000003871 white petrolatum Substances 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 230000003628 erosive effect Effects 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- CUNWUEBNSZSNRX-RKGWDQTMSA-N (2r,3r,4r,5s)-hexane-1,2,3,4,5,6-hexol;(z)-octadec-9-enoic acid Chemical compound OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.OC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O.CCCCCCCC\C=C/CCCCCCCC(O)=O CUNWUEBNSZSNRX-RKGWDQTMSA-N 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010065929 Cardiovascular insufficiency Diseases 0.000 description 1
- 206010017711 Gangrene Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 102000016941 Rho Guanine Nucleotide Exchange Factors Human genes 0.000 description 1
- 108010053823 Rho Guanine Nucleotide Exchange Factors Proteins 0.000 description 1
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 229960005078 sorbitan sesquioleate Drugs 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000012049 topical pharmaceutical composition Substances 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62142097A JPS63303929A (ja) | 1987-06-04 | 1987-06-04 | 創傷治療剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62142097A JPS63303929A (ja) | 1987-06-04 | 1987-06-04 | 創傷治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63303929A JPS63303929A (ja) | 1988-12-12 |
| JPH0156049B2 true JPH0156049B2 (enExample) | 1989-11-28 |
Family
ID=15307358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62142097A Granted JPS63303929A (ja) | 1987-06-04 | 1987-06-04 | 創傷治療剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS63303929A (enExample) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040037828A1 (en) | 2002-07-09 | 2004-02-26 | Bar-Ilan University | Methods and pharmaceutical compositions for healing wounds |
| ATE429925T1 (de) * | 2000-07-31 | 2009-05-15 | Univ Bar Ilan | Methoden und pharmazeutische zusammensetzungen zur wundheilung |
| WO2007026356A2 (en) | 2005-08-29 | 2007-03-08 | Healor Ltd. | Methods and compositions for prevention and treatment of diabetic and aged skin |
| WO2011083483A2 (en) | 2010-01-11 | 2011-07-14 | Healor Ltd. | Method for treatment of inflammatory disease and disorder |
-
1987
- 1987-06-04 JP JP62142097A patent/JPS63303929A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| JPS63303929A (ja) | 1988-12-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US4828832A (en) | Method of manufacturing a composition for treating skin lesions | |
| US6258385B1 (en) | Tetrasilver tetroxide treatment for skin conditions | |
| US4857554A (en) | Method for the treatment of psoriasis | |
| US4749572A (en) | Pharmaceutical preparations | |
| JPS63233925A (ja) | 傷治療のためのインスリン様成長因子‐２の局所使用 | |
| JP2002529411A (ja) | イオン性銀錯体 | |
| JPS62242614A (ja) | 局所適用及び低刺激性の乾癬治療剤 | |
| JPH0533204B2 (enExample) | ||
| CA1238272A (en) | Method and composition for treating skin lesions | |
| JPS604130A (ja) | アデノシン含有医薬製剤 | |
| JPS63159317A (ja) | アラントイン含有水性製剤 | |
| JPH0156049B2 (enExample) | ||
| US5270042A (en) | Medicinal salve composition | |
| US5554593A (en) | Therapeutic agent for threatened abortion | |
| JPH039885B2 (enExample) | ||
| JPH08506336A (ja) | ヨウ素および非還元性糖を含有する創傷治癒組成物 | |
| JP3899267B2 (ja) | 皮膚、粘膜、器官または組織の疾患を治療するためのトシルクロルアミドの使用 | |
| JP2983335B2 (ja) | ホスホマイシン及びその医薬的に許容可能な塩の局所瘢痕形成剤としての使用 | |
| RU2191574C2 (ru) | Лекарственное средство, обладающее регенерирующим и ранозаживляющим действием | |
| JP3877807B2 (ja) | 口内炎治療・予防剤 | |
| RU2097023C1 (ru) | Способ получения мази для местного лечения гнойных ран | |
| RU2097024C1 (ru) | Бактерицидная мазь | |
| PL152379B1 (en) | Procedure for obtaining the preparation for the treatment of the disease psoriasis: drug for the treatment of psoriasis and its application | |
| US3026247A (en) | Pharmaceutical preparation | |
| JPS6222968B2 (enExample) |