JPS63303929A - 創傷治療剤 - Google Patents
創傷治療剤Info
- Publication number
- JPS63303929A JPS63303929A JP62142097A JP14209787A JPS63303929A JP S63303929 A JPS63303929 A JP S63303929A JP 62142097 A JP62142097 A JP 62142097A JP 14209787 A JP14209787 A JP 14209787A JP S63303929 A JPS63303929 A JP S63303929A
- Authority
- JP
- Japan
- Prior art keywords
- ointment
- gentamicin
- insulin
- treating agent
- effective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 claims abstract description 32
- 102000004877 Insulin Human genes 0.000 claims abstract description 16
- 108090001061 Insulin Proteins 0.000 claims abstract description 16
- 229940125396 insulin Drugs 0.000 claims abstract description 16
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 claims abstract description 15
- 229930182566 Gentamicin Natural products 0.000 claims abstract description 15
- 229960002518 gentamicin Drugs 0.000 claims abstract description 15
- 206010052428 Wound Diseases 0.000 claims abstract description 14
- 208000027418 Wounds and injury Diseases 0.000 claims abstract description 14
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 6
- 239000002674 ointment Substances 0.000 abstract description 27
- 206010012601 diabetes mellitus Diseases 0.000 abstract description 10
- 230000035876 healing Effects 0.000 abstract description 4
- 238000007796 conventional method Methods 0.000 abstract description 2
- 238000002156 mixing Methods 0.000 abstract description 2
- 239000004615 ingredient Substances 0.000 abstract 3
- 238000002360 preparation method Methods 0.000 description 7
- RDEIXVOBVLKYNT-VQBXQJRRSA-N (2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[(2r,3r,6s)-3-amino-6-(1-aminoethyl)oxan-2-yl]oxy-2-hydroxycyclohexyl]oxy-5-methyl-4-(methylamino)oxane-3,5-diol;(2r,3r,4r,5r)-2-[(1s,2s,3r,4s,6r)-4,6-diamino-3-[(2r,3r,6s)-3-amino-6-(aminomethyl)oxan-2-yl]o Chemical group OS(O)(=O)=O.O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC[C@@H](CN)O2)N)[C@@H](N)C[C@H]1N.O1C[C@@](O)(C)[C@H](NC)[C@@H](O)[C@H]1O[C@@H]1[C@@H](O)[C@H](O[C@@H]2[C@@H](CC[C@H](O2)C(C)N)N)[C@@H](N)C[C@H]1N.O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N RDEIXVOBVLKYNT-VQBXQJRRSA-N 0.000 description 5
- 229940057995 liquid paraffin Drugs 0.000 description 5
- 239000003814 drug Substances 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- 229940124597 therapeutic agent Drugs 0.000 description 4
- HEMHJVSKTPXQMS-UHFFFAOYSA-M Sodium hydroxide Chemical compound [OH-].[Na+] HEMHJVSKTPXQMS-UHFFFAOYSA-M 0.000 description 3
- 235000019271 petrolatum Nutrition 0.000 description 3
- 239000003871 white petrolatum Substances 0.000 description 3
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 208000025865 Ulcer Diseases 0.000 description 2
- 230000003628 erosive effect Effects 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 231100000397 ulcer Toxicity 0.000 description 2
- JNYAEWCLZODPBN-JGWLITMVSA-N (2r,3r,4s)-2-[(1r)-1,2-dihydroxyethyl]oxolane-3,4-diol Chemical compound OC[C@@H](O)[C@H]1OC[C@H](O)[C@H]1O JNYAEWCLZODPBN-JGWLITMVSA-N 0.000 description 1
- 208000035143 Bacterial infection Diseases 0.000 description 1
- 206010065929 Cardiovascular insufficiency Diseases 0.000 description 1
- 201000006082 Chickenpox Diseases 0.000 description 1
- 208000032544 Cicatrix Diseases 0.000 description 1
- 206010009192 Circulatory collapse Diseases 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- 206010046980 Varicella Diseases 0.000 description 1
- 208000022362 bacterial infectious disease Diseases 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 206010015037 epilepsy Diseases 0.000 description 1
- 238000010438 heat treatment Methods 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 239000004570 mortar (masonry) Substances 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 239000000843 powder Substances 0.000 description 1
- 239000008213 purified water Substances 0.000 description 1
- 231100000241 scar Toxicity 0.000 description 1
- 230000037387 scars Effects 0.000 description 1
- 206010040560 shock Diseases 0.000 description 1
- 239000004094 surface-active agent Substances 0.000 description 1
- 239000012049 topical pharmaceutical composition Substances 0.000 description 1
- 230000002485 urinary effect Effects 0.000 description 1
- 208000019553 vascular disease Diseases 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Landscapes
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62142097A JPS63303929A (ja) | 1987-06-04 | 1987-06-04 | 創傷治療剤 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62142097A JPS63303929A (ja) | 1987-06-04 | 1987-06-04 | 創傷治療剤 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS63303929A true JPS63303929A (ja) | 1988-12-12 |
| JPH0156049B2 JPH0156049B2 (enExample) | 1989-11-28 |
Family
ID=15307358
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62142097A Granted JPS63303929A (ja) | 1987-06-04 | 1987-06-04 | 創傷治療剤 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS63303929A (enExample) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004536018A (ja) * | 2000-07-31 | 2004-12-02 | バル・イラン・ユニバーシティ | 創傷治療のための方法および薬学的組成物 |
| US8093211B2 (en) | 2000-07-31 | 2012-01-10 | Bar-Ilan University | Methods and pharmaceutical compositions for healing wounds |
| US8349793B2 (en) | 2010-01-11 | 2013-01-08 | Heal0r, Ltd. | Method for treatment of inflammatory disease and disorder |
| US8367606B2 (en) | 2005-08-29 | 2013-02-05 | Healor Ltd. | Method and compositions for prevention and treatment of diabetic and aged skin |
-
1987
- 1987-06-04 JP JP62142097A patent/JPS63303929A/ja active Granted
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2004536018A (ja) * | 2000-07-31 | 2004-12-02 | バル・イラン・ユニバーシティ | 創傷治療のための方法および薬学的組成物 |
| JP2011140505A (ja) * | 2000-07-31 | 2011-07-21 | Univ Bar Ilan | 創傷治療のための方法および薬学的組成物 |
| US8093211B2 (en) | 2000-07-31 | 2012-01-10 | Bar-Ilan University | Methods and pharmaceutical compositions for healing wounds |
| US8367606B2 (en) | 2005-08-29 | 2013-02-05 | Healor Ltd. | Method and compositions for prevention and treatment of diabetic and aged skin |
| US8349793B2 (en) | 2010-01-11 | 2013-01-08 | Heal0r, Ltd. | Method for treatment of inflammatory disease and disorder |
Also Published As
| Publication number | Publication date |
|---|---|
| JPH0156049B2 (enExample) | 1989-11-28 |
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