JPH01501864A - 抗ウイルス剤 - Google Patents

抗ウイルス剤

Info

Publication number
JPH01501864A
JPH01501864A JP63501095A JP50109587A JPH01501864A JP H01501864 A JPH01501864 A JP H01501864A JP 63501095 A JP63501095 A JP 63501095A JP 50109587 A JP50109587 A JP 50109587A JP H01501864 A JPH01501864 A JP H01501864A
Authority
JP
Japan
Prior art keywords
guanine
group
compound
ester
propyloxymethyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP63501095A
Other languages
English (en)
Japanese (ja)
Inventor
レイスト、エルマー・ジエイ
スターム、プリツシラ・エイ
Original Assignee
エス・アール・アイ・インターナシヨナル
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by エス・アール・アイ・インターナシヨナル filed Critical エス・アール・アイ・インターナシヨナル
Publication of JPH01501864A publication Critical patent/JPH01501864A/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP63501095A 1987-01-20 1987-12-23 抗ウイルス剤 Pending JPH01501864A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US547187A 1987-01-20 1987-01-20
US005,471 1987-01-20

Publications (1)

Publication Number Publication Date
JPH01501864A true JPH01501864A (ja) 1989-06-29

Family

ID=21716038

Family Applications (1)

Application Number Title Priority Date Filing Date
JP63501095A Pending JPH01501864A (ja) 1987-01-20 1987-12-23 抗ウイルス剤

Country Status (7)

Country Link
EP (1) EP0309491A1 (enrdf_load_stackoverflow)
JP (1) JPH01501864A (enrdf_load_stackoverflow)
DE (1) DE3790883T1 (enrdf_load_stackoverflow)
GB (1) GB2209338A (enrdf_load_stackoverflow)
NL (1) NL8720745A (enrdf_load_stackoverflow)
SE (1) SE8803309L (enrdf_load_stackoverflow)
WO (1) WO1988005438A1 (enrdf_load_stackoverflow)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0335770B1 (en) * 1988-04-01 1997-01-15 Merrell Pharmaceuticals Inc. Novel fluorophosphonate nucleotide derivatives
US5208221A (en) * 1990-11-29 1993-05-04 Bristol-Myers Squibb Company Antiviral (phosphonomethoxy) methoxy purine/pyrimidine derivatives
WO1993006112A1 (en) * 1991-09-24 1993-04-01 The Wellcome Foundation Limited Therapeutic nucleosides
US5532225A (en) * 1992-07-31 1996-07-02 Sri International Acyclic purine phosphonate nucleotide analogs as antiviral agents, and related synthetic methods
US5798340A (en) 1993-09-17 1998-08-25 Gilead Sciences, Inc. Nucleotide analogs
CA2171868A1 (en) * 1993-09-17 1995-03-23 Petr Alexander Method for dosing therapeutic compounds
US5717095A (en) * 1995-12-29 1998-02-10 Gilead Sciences, Inc. Nucleotide analogs
US5877166A (en) * 1996-04-29 1999-03-02 Sri International Enantiomerically pure 2-aminopurine phosphonate nucleotide analogs as antiviral agents
US5922695A (en) 1996-07-26 1999-07-13 Gilead Sciences, Inc. Antiviral phosphonomethyoxy nucleotide analogs having increased oral bioavarilability
US20040224916A1 (en) 2003-01-14 2004-11-11 Gilead Sciences, Inc. Compositions and methods for combination antiviral therapy
TWI471145B (zh) 2005-06-13 2015-02-01 Bristol Myers Squibb & Gilead Sciences Llc 單一式藥學劑量型
TWI375560B (en) 2005-06-13 2012-11-01 Gilead Sciences Inc Composition comprising dry granulated emtricitabine and tenofovir df and method for making the same

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1288098C (en) * 1984-08-24 1991-08-27 Richard L. Tolman 4-(guanin-9-yl)butanals and their 3-oxa, 3-thia and 2-ene derivatives having antiviral and antitumor activity

Also Published As

Publication number Publication date
DE3790883T1 (enrdf_load_stackoverflow) 1988-12-08
GB8821380D0 (en) 1988-11-02
SE8803309D0 (sv) 1988-09-19
SE8803309L (sv) 1988-09-19
EP0309491A1 (en) 1989-04-05
GB2209338A (en) 1989-05-10
NL8720745A (nl) 1988-12-01
WO1988005438A1 (en) 1988-07-28

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