JPH01500270A - ５‐ヘテロ‐またはアリール‐置換された‐イミダゾ［２，１‐ａ］イソキノリン類 - Google Patents
５‐ヘテロ‐またはアリール‐置換された‐イミダゾ［２，１‐ａ］イソキノリン類Info
- Publication number
- JPH01500270A JPH01500270A JP62504237A JP50423787A JPH01500270A JP H01500270 A JPH01500270 A JP H01500270A JP 62504237 A JP62504237 A JP 62504237A JP 50423787 A JP50423787 A JP 50423787A JP H01500270 A JPH01500270 A JP H01500270A
- Authority
- JP
- Japan
- Prior art keywords
- tables
- formula
- phenyl
- formulas
- alkyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/0803—Compounds with Si-C or Si-Si linkages
- C07F7/081—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te
- C07F7/0812—Compounds with Si-C or Si-Si linkages comprising at least one atom selected from the elements N, O, halogen, S, Se or Te comprising a heterocyclic ring
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Pulmonology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88511586A | 1986-07-14 | 1986-07-14 | |
| US885,115 | 1986-07-14 | ||
| US1351587A | 1987-02-11 | 1987-02-11 | |
| US013,515 | 1987-02-11 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPH01500270A true JPH01500270A (ja) | 1989-02-02 |
| JPH0588713B2 JPH0588713B2 (enrdf_load_stackoverflow) | 1993-12-24 |
Family
ID=26684931
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP62504237A Granted JPH01500270A (ja) | 1986-07-14 | 1987-07-07 | ５‐ヘテロ‐またはアリール‐置換された‐イミダゾ［２，１‐ａ］イソキノリン類 |
Country Status (22)
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4910206A (en) * | 1986-07-14 | 1990-03-20 | Sandoz Pharmaceuticals Corp. | 5-hetero-or aryl-substituted-imidazo(2,1-a)isoquinolines and their use as PAF receptor antagonists |
| EP0338993A1 (en) * | 1988-04-21 | 1989-10-25 | Sandoz Ag | 6-Aryl-substituted-4h-thieno[2,3-e][1,2,4]triazolo [3,4-c][1,4]diazepines |
| ES2069606T3 (es) * | 1988-05-05 | 1995-05-16 | Sandoz Ag | 5-aril-sustituido-2,3-dihidro-imidazo(1,2-a)furo(3,2-c)- o tieno(2,3-c)piridinas. |
| US5939090A (en) | 1996-12-03 | 1999-08-17 | 3M Innovative Properties Company | Gel formulations for topical drug delivery |
| CN1076728C (zh) * | 1999-02-05 | 2001-12-26 | 浙江大学 | 2－芳基咪唑并[2,1－a]异喹啉的衍生物及其用途 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1347493A (en) * | 1971-02-11 | 1974-02-27 | Aspro Nicholas Ltd | Benzazine derivatives |
-
1987
- 1987-07-07 EP EP87810387A patent/EP0258175B1/en not_active Expired - Lifetime
- 1987-07-07 HU HU873833A patent/HU206114B/hu not_active IP Right Cessation
- 1987-07-07 WO PCT/EP1987/000366 patent/WO1988000587A2/en active IP Right Grant
- 1987-07-07 ES ES198787810387T patent/ES2032861T3/es not_active Expired - Lifetime
- 1987-07-07 AT AT87810387T patent/ATE74357T1/de not_active IP Right Cessation
- 1987-07-07 DE DE8787810387T patent/DE3777919D1/de not_active Expired - Lifetime
- 1987-07-07 JP JP62504237A patent/JPH01500270A/ja active Granted
- 1987-07-07 AU AU76941/87A patent/AU604739B2/en not_active Ceased
- 1987-07-11 MY MYPI87000989A patent/MY101895A/en unknown
- 1987-07-13 NZ NZ221054A patent/NZ221054A/xx unknown
- 1987-07-13 PL PL1987266801A patent/PL154159B1/pl unknown
- 1987-07-13 IE IE187687A patent/IE60277B1/en not_active IP Right Cessation
- 1987-07-13 IL IL83164A patent/IL83164A/xx unknown
- 1987-07-13 CA CA000542087A patent/CA1317942C/en not_active Expired - Fee Related
- 1987-07-14 PH PH35535A patent/PH24430A/en unknown
-
1988
- 1988-03-11 FI FI881165A patent/FI88159C/fi not_active IP Right Cessation
- 1988-03-11 KR KR88700272A patent/KR960003609B1/ko not_active Expired - Fee Related
- 1988-03-14 DK DK138388A patent/DK170213B1/da not_active IP Right Cessation
-
1992
- 1992-04-02 GR GR920400538T patent/GR3004258T3/el unknown
-
1995
- 1995-01-18 SG SG8595A patent/SG8595G/en unknown
- 1995-05-11 HK HK71295A patent/HK71295A/en not_active IP Right Cessation
- 1995-12-01 CY CY182895A patent/CY1828A/xx unknown
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| JP2007502845A (ja) | がんまたはウイルス疾患を治療するための三環性複素環化合物、組成物および方法 | |
| JP2978850B2 (ja) | ２−アミノベンズアゼピン誘導体 | |
| CA2054091A1 (en) | Isoquinolinone derivatives | |
| EP1490361B1 (en) | Polycyclic compounds as potent alpha2-adrenoceptor antagonists | |
| WO2012070015A1 (en) | Inhibitors of the activity of complex iii of the mitochondrial electron transport chain and use thereof for treating diseases | |
| JPS6267081A (ja) | Ｐａｆきつ抗剤としての新規な２，５−ジアリ−ルテトラヒドロチオフエン類及びその類縁体 | |
| JPS6028979A (ja) | イミダゾキナゾリン類化合物 | |
| EP0154887B1 (en) | New 2,5-diaryl tetrahydrothiophenes and analogs thereof as paf-antagonists | |
| RU2001911C1 (ru) | Способ получени замещенных 1,2,3,4-тетрагидронафталинов или их фармацевтически приемлемых аддитивных солей кислоты | |
| EP0365089A2 (en) | 2-Aryl-5(3-methoxy-5-(hydroxypropylsulfonyl)-4-propoxyphenyl) tetrahydrothiophen and analogs | |
| DK175801B1 (da) | Anvendelse af substituerede alkylidendithio-bis-(substituerede)-phenoler til fremstilling af et lægemiddel til inhibering af interleukin-1-medierede virkninger bortset fra atherosklerose og/eller hyperlipidæmi | |
| JPH01500270A (ja) | ５‐ヘテロ‐またはアリール‐置換された‐イミダゾ［２，１‐ａ］イソキノリン類 | |
| US4992428A (en) | 5-aryl-substituted-2,3-dihydro-imidazo[1,2-a]furo- and thieno pyridines | |
| JPH06507377A (ja) | 薬剤組成物 | |
| JPS60218377A (ja) | ４−フエニルフタラジン誘導体及びそれを有効成分とする循環改善剤 | |
| EP0194665A1 (en) | beta-Adrenergic receptor agonist alkylaminoalkyl pyridinemethanol derivatives | |
| JPH0631228B2 (ja) | 新規な５―（ω―アンモニオアシルオキシメチレン）テトラヒドロフラン類及びテトラヒドロチオフェン類、それらの製造法並びにそれらを含有する抗ＰＡＦ剤 | |
| FI85481B (fi) | Foerfarande foer framstaellning av 2,3 -dihydro-1-(8-metyl-1,2,4-triazolo/4,3-b/pyridazin-6-yl)-4(1h) -pyridinon. | |
| WO1988006157A1 (en) | 5-HETERO- OR ARYL-SUBSTITUTED-IMIDAZO[2,1-a]ISOQUINOLINES | |
| US4988735A (en) | Ethylene diamine active cardiovascular therapy | |
| JPH11310530A (ja) | 一酸化窒素産生抑制剤 | |
| JPS58121214A (ja) | 血小板凝集阻害剤 | |
| JPH0615540B2 (ja) | 新規なグリセロールアセタールのアミノアシレート類、それらの製造方法及びそれらを含む医薬組成物 | |
| WO2001064682A1 (fr) | Nouveau compose dote d'une activite antipaludique | |
| JP6129951B2 (ja) | 新規ピリド［３，４−ｃ］［１，９］フェナントロリンおよび１１，１２ジヒドロピリド［３，４，−ｃ］［１，９］フェナントロリン誘導体、ならびに、特にがんを治療するためのその使用 |