JPH0142927B2 - - Google Patents
Info
- Publication number
- JPH0142927B2 JPH0142927B2 JP55106455A JP10645580A JPH0142927B2 JP H0142927 B2 JPH0142927 B2 JP H0142927B2 JP 55106455 A JP55106455 A JP 55106455A JP 10645580 A JP10645580 A JP 10645580A JP H0142927 B2 JPH0142927 B2 JP H0142927B2
- Authority
- JP
- Japan
- Prior art keywords
- activated carbon
- microcapsules
- patient
- day
- toxic substances
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 claims description 59
- 239000003094 microcapsule Substances 0.000 claims description 9
- GOZDTZWAMGHLDY-UHFFFAOYSA-L sodium picosulfate Chemical compound [Na+].[Na+].C1=CC(OS(=O)(=O)[O-])=CC=C1C(C=1N=CC=CC=1)C1=CC=C(OS([O-])(=O)=O)C=C1 GOZDTZWAMGHLDY-UHFFFAOYSA-L 0.000 claims description 8
- 229960005077 sodium picosulfate Drugs 0.000 claims description 8
- 229920000642 polymer Polymers 0.000 claims description 6
- 239000011301 petroleum pitch Substances 0.000 claims description 3
- 230000002378 acidificating effect Effects 0.000 claims description 2
- 230000007935 neutral effect Effects 0.000 claims description 2
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 12
- 231100000614 poison Toxicity 0.000 description 7
- 238000001179 sorption measurement Methods 0.000 description 7
- 239000003440 toxic substance Substances 0.000 description 7
- LEHOTFFKMJEONL-UHFFFAOYSA-N Uric Acid Chemical compound N1C(=O)NC(=O)C2=C1NC(=O)N2 LEHOTFFKMJEONL-UHFFFAOYSA-N 0.000 description 6
- TVWHNULVHGKJHS-UHFFFAOYSA-N Uric acid Natural products N1C(=O)NC(=O)C2NC(=O)NC21 TVWHNULVHGKJHS-UHFFFAOYSA-N 0.000 description 6
- 239000011248 coating agent Substances 0.000 description 6
- 229940109239 creatinine Drugs 0.000 description 6
- 230000000694 effects Effects 0.000 description 6
- 229940116269 uric acid Drugs 0.000 description 6
- 206010010774 Constipation Diseases 0.000 description 5
- 238000000576 coating method Methods 0.000 description 5
- 229920000623 Cellulose acetate phthalate Polymers 0.000 description 4
- UIIMBOGNXHQVGW-UHFFFAOYSA-M Sodium bicarbonate Chemical compound [Na+].OC([O-])=O UIIMBOGNXHQVGW-UHFFFAOYSA-M 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 229940081734 cellulose acetate phthalate Drugs 0.000 description 4
- 229920003132 hydroxypropyl methylcellulose phthalate Polymers 0.000 description 4
- 229940031704 hydroxypropyl methylcellulose phthalate Drugs 0.000 description 4
- 210000000936 intestine Anatomy 0.000 description 4
- 210000002784 stomach Anatomy 0.000 description 4
- 208000020832 chronic kidney disease Diseases 0.000 description 3
- 208000022831 chronic renal failure syndrome Diseases 0.000 description 3
- 230000003247 decreasing effect Effects 0.000 description 3
- 238000000502 dialysis Methods 0.000 description 3
- 239000008141 laxative Substances 0.000 description 3
- 210000000214 mouth Anatomy 0.000 description 3
- 210000002700 urine Anatomy 0.000 description 3
- 101000856500 Bacillus subtilis subsp. natto Glutathione hydrolase proenzyme Proteins 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 230000002354 daily effect Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 229940125722 laxative agent Drugs 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 239000003208 petroleum Substances 0.000 description 2
- 239000000843 powder Substances 0.000 description 2
- 229910000030 sodium bicarbonate Inorganic materials 0.000 description 2
- 235000017557 sodium bicarbonate Nutrition 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- 230000009747 swallowing Effects 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 230000009885 systemic effect Effects 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- 125000003903 2-propenyl group Chemical group [H]C([*])([H])C([H])=C([H])[H] 0.000 description 1
- 208000037157 Azotemia Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- 206010060891 General symptom Diseases 0.000 description 1
- -1 Laxoberone Chemical compound 0.000 description 1
- 206010067125 Liver injury Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 208000001647 Renal Insufficiency Diseases 0.000 description 1
- PMZURENOXWZQFD-UHFFFAOYSA-L Sodium Sulfate Chemical compound [Na+].[Na+].[O-]S([O-])(=O)=O PMZURENOXWZQFD-UHFFFAOYSA-L 0.000 description 1
- 102000005262 Sulfatase Human genes 0.000 description 1
- 235000010290 biphenyl Nutrition 0.000 description 1
- 239000004305 biphenyl Substances 0.000 description 1
- 125000006267 biphenyl group Chemical group 0.000 description 1
- 229910052799 carbon Inorganic materials 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000000151 deposition Methods 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 231100000234 hepatic damage Toxicity 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 201000006370 kidney failure Diseases 0.000 description 1
- 230000002475 laxative effect Effects 0.000 description 1
- 230000008818 liver damage Effects 0.000 description 1
- 208000019423 liver disease Diseases 0.000 description 1
- 229920003145 methacrylic acid copolymer Polymers 0.000 description 1
- 229940117841 methacrylic acid copolymer Drugs 0.000 description 1
- IWVKTOUOPHGZRX-UHFFFAOYSA-N methyl 2-methylprop-2-enoate;2-methylprop-2-enoic acid Chemical compound CC(=C)C(O)=O.COC(=O)C(C)=C IWVKTOUOPHGZRX-UHFFFAOYSA-N 0.000 description 1
- 150000004682 monohydrates Chemical class 0.000 description 1
- 239000002103 nanocoating Substances 0.000 description 1
- 239000002245 particle Substances 0.000 description 1
- ZUOUZKKEUPVFJK-UHFFFAOYSA-N phenylbenzene Natural products C1=CC=CC=C1C1=CC=CC=C1 ZUOUZKKEUPVFJK-UHFFFAOYSA-N 0.000 description 1
- 210000000813 small intestine Anatomy 0.000 description 1
- 229910052938 sodium sulfate Inorganic materials 0.000 description 1
- 235000011152 sodium sulphate Nutrition 0.000 description 1
- 239000012798 spherical particle Substances 0.000 description 1
- 238000005507 spraying Methods 0.000 description 1
- 108060007951 sulfatase Proteins 0.000 description 1
- 208000009852 uremia Diseases 0.000 description 1
Landscapes
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10645580A JPS5731864A (en) | 1980-08-04 | 1980-08-04 | Oral activated carbon microcapsule |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP10645580A JPS5731864A (en) | 1980-08-04 | 1980-08-04 | Oral activated carbon microcapsule |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JPS5731864A JPS5731864A (en) | 1982-02-20 |
| JPH0142927B2 true JPH0142927B2 (de) | 1989-09-18 |
Family
ID=14434060
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP10645580A Granted JPS5731864A (en) | 1980-08-04 | 1980-08-04 | Oral activated carbon microcapsule |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JPS5731864A (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0724441A1 (de) * | 1993-10-19 | 1996-08-07 | The Procter & Gamble Company | Natriumpicosulfat enthaltende dosierungsform |
| JPH10316578A (ja) * | 1997-05-13 | 1998-12-02 | Kureha Chem Ind Co Ltd | リポタンパク質リパーゼ低血症改善剤 |
| JPH1129485A (ja) * | 1997-07-10 | 1999-02-02 | Kureha Chem Ind Co Ltd | 抗肥満剤 |
| US6706287B2 (en) * | 2001-05-15 | 2004-03-16 | Kibow Biotech Inc. | Prebiotic and probiotic compositions and methods for their use in gut-based therapies |
| JP2005162683A (ja) * | 2003-12-03 | 2005-06-23 | Kureha Chem Ind Co Ltd | 高尿酸血症の治療又は予防剤 |
| WO2005105068A1 (en) * | 2004-04-15 | 2005-11-10 | Dow Global Technologies Inc. | In vivo stimulation of intestinal transporters for excretion of nitrogenous wastes |
| RU2473332C2 (ru) * | 2007-10-12 | 2013-01-27 | Ферринг Интернэшнл Сентер С.А. | Способ изготовления фармацевтического продукта, содержащего лимонную кислоту, оксид магния, бикарбонат калия и пикосульфат натрия, фармацевтические композиции, содержащие гранулы, полученные таким способом, и промежуточное соединение |
| GB201204696D0 (en) * | 2012-03-16 | 2012-05-02 | Ucl Business Plc | Therapy |
| WO2017073531A1 (ja) * | 2015-10-26 | 2017-05-04 | 第一三共株式会社 | 多孔質材料の大腸または小腸下部へのデリバリー製剤 |
Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4839620A (de) * | 1971-09-27 | 1973-06-11 | ||
| JPS5065486A (de) * | 1973-10-15 | 1975-06-03 | ||
| JPS5070288A (de) * | 1973-07-05 | 1975-06-11 | ||
| JPS51151693A (en) * | 1975-06-23 | 1976-12-27 | Eisai Co Ltd | Coated bead-like activated carbon for blood purification |
| US4122169A (en) * | 1976-04-27 | 1978-10-24 | Geils John H | Activated carbon-sorbital composition and adsorption-expulsion treatment therewith |
| JPS5489010A (en) * | 1977-12-27 | 1979-07-14 | Kureha Chem Ind Co Ltd | Spherical activated charcoal antidote |
| JPS54159393A (en) * | 1978-06-08 | 1979-12-17 | Ajinomoto Co Inc | Polyamino acid-coated activated carbon |
| JPS5544369A (en) * | 1978-09-26 | 1980-03-28 | Kureha Chem Ind Co Ltd | Adsorbent |
-
1980
- 1980-08-04 JP JP10645580A patent/JPS5731864A/ja active Granted
Patent Citations (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS4839620A (de) * | 1971-09-27 | 1973-06-11 | ||
| JPS5070288A (de) * | 1973-07-05 | 1975-06-11 | ||
| JPS5065486A (de) * | 1973-10-15 | 1975-06-03 | ||
| JPS51151693A (en) * | 1975-06-23 | 1976-12-27 | Eisai Co Ltd | Coated bead-like activated carbon for blood purification |
| US4122169A (en) * | 1976-04-27 | 1978-10-24 | Geils John H | Activated carbon-sorbital composition and adsorption-expulsion treatment therewith |
| JPS5489010A (en) * | 1977-12-27 | 1979-07-14 | Kureha Chem Ind Co Ltd | Spherical activated charcoal antidote |
| JPS54159393A (en) * | 1978-06-08 | 1979-12-17 | Ajinomoto Co Inc | Polyamino acid-coated activated carbon |
| JPS5544369A (en) * | 1978-09-26 | 1980-03-28 | Kureha Chem Ind Co Ltd | Adsorbent |
Also Published As
| Publication number | Publication date |
|---|---|
| JPS5731864A (en) | 1982-02-20 |
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