JPH0133445B2 - - Google Patents

Info

Publication number
JPH0133445B2
JPH0133445B2 JP51121183A JP12118376A JPH0133445B2 JP H0133445 B2 JPH0133445 B2 JP H0133445B2 JP 51121183 A JP51121183 A JP 51121183A JP 12118376 A JP12118376 A JP 12118376A JP H0133445 B2 JPH0133445 B2 JP H0133445B2
Authority
JP
Japan
Prior art keywords
globules
drug
albumin
release
percent
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
JP51121183A
Other languages
English (en)
Japanese (ja)
Other versions
JPS5247912A (en
Inventor
Furanshisu Yaperu Junia Antonii
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
3M Co
Original Assignee
Minnesota Mining and Manufacturing Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Minnesota Mining and Manufacturing Co filed Critical Minnesota Mining and Manufacturing Co
Publication of JPS5247912A publication Critical patent/JPS5247912A/ja
Publication of JPH0133445B2 publication Critical patent/JPH0133445B2/ja
Granted legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1658Proteins, e.g. albumin, gelatin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T428/00Stock material or miscellaneous articles
    • Y10T428/29Coated or structually defined flake, particle, cell, strand, strand portion, rod, filament, macroscopic fiber or mass thereof
    • Y10T428/2982Particulate matter [e.g., sphere, flake, etc.]
    • Y10T428/2989Microcapsule with solid core [includes liposome]

Landscapes

  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP51121183A 1975-10-09 1976-10-08 Solid serum albumin circles and its production Granted JPS5247912A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US62114575A 1975-10-09 1975-10-09

Publications (2)

Publication Number Publication Date
JPS5247912A JPS5247912A (en) 1977-04-16
JPH0133445B2 true JPH0133445B2 (en:Method) 1989-07-13

Family

ID=24488920

Family Applications (1)

Application Number Title Priority Date Filing Date
JP51121183A Granted JPS5247912A (en) 1975-10-09 1976-10-08 Solid serum albumin circles and its production

Country Status (9)

Country Link
US (1) US4147767A (en:Method)
JP (1) JPS5247912A (en:Method)
AU (1) AU513080B2 (en:Method)
CA (1) CA1077842A (en:Method)
CH (1) CH629666A5 (en:Method)
DE (1) DE2645553C2 (en:Method)
FR (1) FR2326934A1 (en:Method)
GB (1) GB1567763A (en:Method)
SE (1) SE443086B (en:Method)

Families Citing this family (150)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4357259A (en) * 1977-08-01 1982-11-02 Northwestern University Method of incorporating water-soluble heat-sensitive therapeutic agents in albumin microspheres
US4129659A (en) * 1977-08-08 1978-12-12 The University Of Miami Method for improving cardiovascular function with salinomycin
US4247406A (en) 1979-04-23 1981-01-27 Widder Kenneth J Intravascularly-administrable, magnetically-localizable biodegradable carrier
US4345588A (en) * 1979-04-23 1982-08-24 Northwestern University Method of delivering a therapeutic agent to a target capillary bed
US4331654A (en) 1980-06-13 1982-05-25 Eli Lilly And Company Magnetically-localizable, biodegradable lipid microspheres
JPS5726625A (en) * 1980-07-24 1982-02-12 Japan Atom Energy Res Inst Sustained release type composite material entrapping medical enzyme and its preparation
US4349530A (en) * 1980-12-11 1982-09-14 The Ohio State University Implants, microbeads, microcapsules, preparation thereof and method of administering a biologically-active substance to an animal
JPS57144082U (en:Method) * 1981-03-04 1982-09-09
JPS5811833A (ja) * 1981-07-15 1983-01-22 Hitachi Zosen Corp スラリ−濃度計測装置
FR2520229A1 (fr) * 1982-01-26 1983-07-29 Japan Atomic Energy Res Inst Procede de production d'un compose a degagement lent
EP0086627B1 (en) * 1982-02-12 1985-08-28 Unitika Ltd. Anti-cancer device
JPS58162595A (ja) * 1982-03-19 1983-09-27 Green Cross Corp:The 徐放性アルブミン複合体の製法
US4798786A (en) * 1982-05-06 1989-01-17 Stolle Research And Development Corporation Living cells encapsulated in crosslinked protein
US4622219A (en) * 1983-06-17 1986-11-11 Haynes Duncan H Method of inducing local anesthesia using microdroplets of a general anesthetic
EP0129619B1 (en) * 1983-06-22 1988-05-18 The Stolle Research And Development Corporation Encapsulated cells, their method of preparation and use
US4671954A (en) * 1983-12-13 1987-06-09 University Of Florida Microspheres for incorporation of therapeutic substances and methods of preparation thereof
GB2160312B (en) * 1984-04-13 1987-09-16 South African Inventions Adjuvant for immunisation
FR2565102B1 (fr) * 1984-06-05 1987-03-20 Paris Sud Universite Microcapsules biodegradables a base de serumalbumine, leur preparation et leur application a la liberation in situ de medicuments
US4789501A (en) * 1984-11-19 1988-12-06 The Curators Of The University Of Missouri Glass microspheres
CS255758B1 (en) * 1985-12-11 1988-03-15 Frantisek Rypacek Preparat for the diagnostic of transportion function of oviduct and process for preparing thereof
USRE35862E (en) * 1986-08-18 1998-07-28 Emisphere Technologies, Inc. Delivery systems for pharmacological agents encapsulated with proteinoids
US5055300A (en) * 1988-06-17 1991-10-08 Basic Bio Systems, Inc. Time release protein
US5023080A (en) * 1988-06-17 1991-06-11 Basic Bio Systems, Inc. Time release protein
FR2635459B1 (fr) * 1988-08-17 1992-06-19 Cird Procede de fabrication de microspheres par reticulation de proteines, microspheres ainsi obtenues et leurs utilisations
US5084276A (en) * 1990-01-05 1992-01-28 Abbott Laboratories Quinolone carboxylic acid compositions with polymeric additive to reduce vein irritation
FR2663223B1 (fr) * 1990-06-14 1994-12-02 Af Aplicaciones Far Lab Forme galenique parenterale.
FR2663224B1 (fr) * 1990-06-14 1995-01-20 Applicationes Farmaceuticas Sa Forme galenique parenterale.
US5629020A (en) 1994-04-22 1997-05-13 Emisphere Technologies, Inc. Modified amino acids for drug delivery
US5447728A (en) * 1992-06-15 1995-09-05 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US6099856A (en) 1992-06-15 2000-08-08 Emisphere Technologies, Inc. Active agent transport systems
US5714167A (en) 1992-06-15 1998-02-03 Emisphere Technologies, Inc. Active agent transport systems
US5693338A (en) 1994-09-29 1997-12-02 Emisphere Technologies, Inc. Diketopiperazine-based delivery systems
US5578323A (en) 1992-06-15 1996-11-26 Emisphere Technologies, Inc. Proteinoid carriers and methods for preparation and use thereof
US6331318B1 (en) 1994-09-30 2001-12-18 Emisphere Technologies Inc. Carbon-substituted diketopiperazine delivery systems
US5451410A (en) * 1993-04-22 1995-09-19 Emisphere Technologies, Inc. Modified amino acids for encapsulating active agents
US5541155A (en) 1994-04-22 1996-07-30 Emisphere Technologies, Inc. Acids and acid salts and their use in delivery systems
US5443841A (en) * 1992-06-15 1995-08-22 Emisphere Technologies, Inc. Proteinoid microspheres and methods for preparation and use thereof
US6221367B1 (en) 1992-06-15 2001-04-24 Emisphere Technologies, Inc. Active agent transport systems
US5616311A (en) * 1991-01-15 1997-04-01 Hemosphere, Inc. Non-crosslinked protein particles for therapeutic and diagnostic use
US5725804A (en) * 1991-01-15 1998-03-10 Hemosphere, Inc. Non-crosslinked protein particles for therapeutic and diagnostic use
WO1996039128A1 (en) * 1995-06-06 1996-12-12 Hemosphere, Inc. Protein particles for therapeutic and diagnostic use
US6391343B1 (en) 1991-01-15 2002-05-21 Hemosphere, Inc. Fibrinogen-coated particles for therapeutic use
GB9107628D0 (en) * 1991-04-10 1991-05-29 Moonbrook Limited Preparation of diagnostic agents
US5993805A (en) * 1991-04-10 1999-11-30 Quadrant Healthcare (Uk) Limited Spray-dried microparticles and their use as therapeutic vehicles
AU2572692A (en) 1991-09-09 1993-04-05 Government Of The United States Of America, As Represented By The Secretary Of The Department Of Health And Human Services, The Methods and devices for treating hemophilia and aids
US5429822A (en) * 1992-03-13 1995-07-04 Cambridge Scientific, Inc. Biodegradable bursting release system
US5792451A (en) 1994-03-02 1998-08-11 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US6916489B2 (en) 1992-06-15 2005-07-12 Emisphere Technologies, Inc. Active agent transport systems
US5811127A (en) 1992-06-15 1998-09-22 Emisphere Technologies, Inc. Desferrioxamine oral delivery system
US7425543B2 (en) * 1992-11-16 2008-09-16 The Corporation Of Mercer University Microencapsulated materials and method of making same
EP0646000A4 (en) 1992-11-16 1997-05-02 Univ Mercer COMPOSITIONS CONTAINING MICRO-ENCODED NEUTRALIZING ANTIBODIES.
US5401516A (en) * 1992-12-21 1995-03-28 Emisphere Technologies, Inc. Modified hydrolyzed vegetable protein microspheres and methods for preparation and use thereof
US5340614A (en) * 1993-02-11 1994-08-23 Minnesota Mining And Manufacturing Company Methods of polymer impregnation
US20070116761A1 (en) * 1993-02-22 2007-05-24 Desai Neil P Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US20030133955A1 (en) * 1993-02-22 2003-07-17 American Bioscience, Inc. Methods and compositions useful for administration of chemotherapeutic agents
US20030068362A1 (en) * 1993-02-22 2003-04-10 American Bioscience, Inc. Methods and formulations for the delivery of pharmacologically active agents
US6090925A (en) 1993-03-09 2000-07-18 Epic Therapeutics, Inc. Macromolecular microparticles and methods of production and use
JPH08507806A (ja) * 1993-03-09 1996-08-20 ミドルセツクス・サイエンシーズ・インコーポレーテツド 高分子の微粒子および調製法
US5456917A (en) * 1993-04-12 1995-10-10 Cambridge Scientific, Inc. Method for making a bioerodible material for the sustained release of a medicament and the material made from the method
US5958457A (en) 1993-04-22 1999-09-28 Emisphere Technologies, Inc. Compositions for the delivery of antigens
US20010003001A1 (en) 1993-04-22 2001-06-07 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6461643B2 (en) 1993-04-22 2002-10-08 Emisphere Technologies, Inc. Oral drug delivery compositions and methods
US5709861A (en) 1993-04-22 1998-01-20 Emisphere Technologies, Inc. Compositions for the delivery of antigens
EP0696208B1 (en) 1993-04-22 2001-08-22 Emisphere Technologies, Inc. Oral drug delivery compositions
US5643957A (en) 1993-04-22 1997-07-01 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5739004A (en) * 1993-05-20 1998-04-14 Minnesota Mining And Manufacturing Company Biological sterilization indication for use with or without test pack materials or devices
WO1994028878A1 (en) * 1993-06-14 1994-12-22 Emisphere Technologies, Inc. Proteinoid carriers
GB9423419D0 (en) * 1994-11-19 1995-01-11 Andaris Ltd Preparation of hollow microcapsules
BR9604880A (pt) 1995-03-31 1998-05-19 Emisphere Tech Inc Composto composição forma de unidade de dosagem métodos para administração de um agente biologicamente ativo para preparar uma composição para administração de um agente ativo e para preparar um composto e composição farmacológica
US6001347A (en) 1995-03-31 1999-12-14 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6090958A (en) 1995-03-31 2000-07-18 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
WO1997036480A1 (en) 1996-03-29 1997-10-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5866536A (en) 1995-03-31 1999-02-02 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5650386A (en) 1995-03-31 1997-07-22 Emisphere Technologies, Inc. Compositions for oral delivery of active agents
US5989539A (en) 1995-03-31 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5965121A (en) 1995-03-31 1999-10-12 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5820881A (en) 1995-04-28 1998-10-13 Emisphere Technologies, Inc. Microspheres of diamide-dicarboxylic acids
US6214331B1 (en) 1995-06-06 2001-04-10 C. R. Bard, Inc. Process for the preparation of aqueous dispersions of particles of water-soluble polymers and the particles obtained
US6051258A (en) 1995-06-07 2000-04-18 Emisphere Technologies, Inc. Proteinoid emulsions and methods for preparation and use thereof
US5667806A (en) 1995-06-07 1997-09-16 Emisphere Technologies, Inc. Spray drying method and apparatus
US5750147A (en) 1995-06-07 1998-05-12 Emisphere Technologies, Inc. Method of solubilizing and encapsulating itraconazole
US5824345A (en) 1995-06-07 1998-10-20 Emisphere Technologies, Inc. Fragrances and flavorants
GB2320248B (en) 1995-09-11 1999-04-14 Emisphere Tech Inc Method for preparing omega-aminoalkanoic acid derivatives from cycloalkanones
ES2306452T3 (es) * 1995-10-17 2008-11-01 Jagotec Ag Aporte de farmacos insolubles.
CA2258264A1 (en) 1996-06-14 1997-12-18 Emisphere Technologies, Inc. Microencapsulated fragrances and method for preparation
US7255877B2 (en) * 1996-08-22 2007-08-14 Jagotec Ag Fenofibrate microparticles
US6465016B2 (en) 1996-08-22 2002-10-15 Research Triangle Pharmaceuticals Cyclosporiine particles
US6017310A (en) * 1996-09-07 2000-01-25 Andaris Limited Use of hollow microcapsules
US20070092563A1 (en) 1996-10-01 2007-04-26 Abraxis Bioscience, Inc. Novel formulations of pharmacological agents, methods for the preparation thereof and methods for the use thereof
US6391303B1 (en) 1996-11-18 2002-05-21 Emisphere Technologies, Inc. Methods and compositions for inducing oral tolerance in mammals
US6068600A (en) * 1996-12-06 2000-05-30 Quadrant Healthcare (Uk) Limited Use of hollow microcapsules
AU5871898A (en) * 1997-01-30 1998-08-25 Andaris Limited Microparticles and their use in cancer treatment
US6313088B1 (en) 1997-02-07 2001-11-06 Emisphere Technologies, Inc. 8-[(2-hydroxy-4-methoxy benzoyl) amino]-octanoic acid compositions for delivering active agents
US5879681A (en) 1997-02-07 1999-03-09 Emisphere Technolgies Inc. Compounds and compositions for delivering active agents
US5990166A (en) 1997-02-07 1999-11-23 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6060513A (en) 1997-02-07 2000-05-09 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5876710A (en) 1997-02-07 1999-03-02 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US5804688A (en) 1997-02-07 1998-09-08 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US6358504B1 (en) 1997-02-07 2002-03-19 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5939381A (en) 1997-02-07 1999-08-17 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5863944A (en) 1997-04-30 1999-01-26 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
US5962710A (en) 1997-05-09 1999-10-05 Emisphere Technologies, Inc. Method of preparing salicyloylamino acids
CA2294494A1 (en) * 1997-06-05 1998-12-10 Richard C. K. Yen Fibrinogen-coated microspheres
US20030199425A1 (en) * 1997-06-27 2003-10-23 Desai Neil P. Compositions and methods for treatment of hyperplasia
JP4865937B2 (ja) * 1997-06-27 2012-02-01 アブラクシス バイオサイエンス、エルエルシー パクリタキセル製剤
US6150505A (en) * 1997-09-19 2000-11-21 Hadasit Medical Research Services & Development Ltd. Fibrin microbeads prepared from fibrinogen, thrombin and factor XIII
DE69908304T2 (de) * 1998-02-11 2004-02-19 Rtp Pharma Corp. Ungesättigte fettsäure und steroide enthaltende kombinationspräparate zur behandlung von entzündungen
US6979456B1 (en) 1998-04-01 2005-12-27 Jagotec Ag Anticancer compositions
ATE259220T1 (de) 1998-05-29 2004-02-15 Skyepharma Canada Inc Gegen hitzeeinwirkung geschützte mikropartikel und verfahren zur terminalen dampfsterilisation derselben
KR20010074777A (ko) 1998-07-27 2001-08-09 추후제출 활성제의 폐를 통한 전달
US6440929B1 (en) 1998-07-27 2002-08-27 Emisphere Technologies, Inc. Pulmonary delivery of active agents
US6991798B1 (en) 1998-08-07 2006-01-31 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
KR100659753B1 (ko) * 1998-08-07 2006-12-20 에미스페어 테크놀로지스, 인코포레이티드 활성제 전달용 화합물 및 조성물
EP1105096B1 (en) * 1998-08-19 2003-10-29 Skyepharma Canada Inc. Injectable aqueous dispersions of propofol
GB9819272D0 (en) * 1998-09-03 1998-10-28 Andaris Ltd Microparticles
HK1042856B (zh) 1998-11-20 2007-07-27 Skyepharma Canada Inc. 可分散的磷脂稳定的微粒
DE19858188A1 (de) * 1998-12-17 2000-07-06 Centeon Pharma Gmbh Verfahren zum Auflösen von Albuminflocken in einer Flüssigkeit sowie Einrichtung zur Durchführung des Verfahrens
JP2002534363A (ja) 1999-01-08 2002-10-15 エミスフェアー・テクノロジーズ・インク ポリマー性デリバリー剤及びデリバリー剤化合物
MXPA01008611A (es) 1999-02-26 2003-06-24 Emisphere Tech Inc Compuestos y composiciones para suministrar agentes activos.
DE60017888T2 (de) * 1999-04-05 2006-01-19 Emisphere Technologies, Inc. Dinatrium-salze, monohydrate und ethanol-solvate
AU7984200A (en) * 1999-09-21 2001-04-24 Skyepharma Canada Inc. Surface modified particulate compositions of biologically active substances
US7279597B1 (en) 1999-11-05 2007-10-09 Emisphere Technologies, Inc. Phenyl amine carboxylic acid compounds and compositions for delivering active agents
US7129274B1 (en) 1999-11-05 2006-10-31 Emisphere Technologies Inc. Phenoxy carboxylic acid compounds and compositions for delivering active agents
EP1237872B1 (en) 1999-12-16 2008-02-27 Emisphere Technologies, Inc. Compounds and compositions for delivering active agents
CN1313080C (zh) 2000-04-20 2007-05-02 斯凯伊药品加拿大公司 改进的水不溶性药物粒子的制备方法
AU2001288471B2 (en) 2000-08-31 2006-03-02 Rtp Pharma Inc. Milled particles
JP2004509146A (ja) * 2000-09-20 2004-03-25 スカイファーマ・カナダ・インコーポレーテッド 安定化フィブレート微粒子
US8586094B2 (en) * 2000-09-20 2013-11-19 Jagotec Ag Coated tablets
WO2002067901A1 (en) * 2001-02-22 2002-09-06 Skyepharma Canada Inc. Fibrate-statin combinations with reduced fed-fasted effects
DE10113884B4 (de) * 2001-03-21 2005-06-02 Basf Coatings Ag Verfahren zum Beschichten mikroporöser Oberflächen und Verwendung des Verfahrens
US20030225300A1 (en) * 2001-04-19 2003-12-04 Emisphere Technologies Inc. Compounds and compositions for delivering active agents
US6552172B2 (en) * 2001-08-30 2003-04-22 Habto Biotech, Inc. Fibrin nanoparticles and uses thereof
JP2005209106A (ja) * 2004-01-26 2005-08-04 Nec Corp 携帯通信端末、受信メール管理方法、プログラムおよび記録媒体
US20090280534A1 (en) * 2004-12-22 2009-11-12 Novozymes A/S Recombinant Production of Serum Albumin
US20060182780A1 (en) * 2005-02-16 2006-08-17 Riley Susan L Resorbable hollow devices for implantation and delivery of therapeutic agents
US10004790B2 (en) 2008-09-29 2018-06-26 The Corporation Of Mercer University Nanospheres encapsulating bioactive material and method for formulation of nanospheres
US10463608B2 (en) 2008-09-29 2019-11-05 The Corporation Of Mercer University Microneedle-based transdermal delivery system and method of making same
JP2012504150A (ja) * 2008-09-29 2012-02-16 ザ・コーポレーション・オブ・メイサー・ユニバーシティー 生体活性材料をカプセル化したナノスフェアおよびナノスフェアの製剤化のための方法
US11524058B2 (en) 2008-09-29 2022-12-13 The Corporation Of Mercer University Oral dissolving films containing microencapsulated vaccines and methods of making same
US10603287B2 (en) * 2016-07-20 2020-03-31 Ptlnv, Llc, Series Three (3) Albumin nanosphere preparations to control bleeding from surgical operations
EP2921166B1 (en) * 2012-11-15 2017-06-14 Utah-Inha DDS & Advanced Therapeutics Research Center Biodegradable microbeads with improved anticancer drug adsorptivity, containing albumin and dextran sulfate, and preparation method therefor
US9999676B2 (en) 2012-11-27 2018-06-19 Utah-Inha Dds & Advanced Therapeutics Research Center Biodegradable microbead comprising anionic polymer for improving adsorptive power to anticancer drugs, and method for preparing same
US12239822B2 (en) 2013-03-15 2025-03-04 Windgap Medical, Inc. Portable drug mixing and delivery device and associated methods
WO2015095624A2 (en) * 2013-12-18 2015-06-25 Windgap Medical, Inc. Drug mixing and delivery system and method
US9474834B2 (en) * 2014-04-11 2016-10-25 Abbott Cardiovascular Systems Inc. Stent with albumin coating for enhanced thromboresistance
HK1244450A1 (zh) 2014-12-18 2018-08-10 温德加普医疗股份有限公司 用於溶解或增溶治疗剂的方法和组合物
WO2017062463A1 (en) 2015-10-05 2017-04-13 The Corporation Of Mercer University Nanospheres encapsulating bioactive material and method for formulation of nanospheres
US11628208B2 (en) 2015-10-05 2023-04-18 The Corporation Of Mercer University System and method for microneedle delivery of microencapsulated vaccine and bioactive proteins
US20190142748A1 (en) * 2016-05-26 2019-05-16 Zhuhai Beihai Biotech Co., Ltd. Formulations of chlorambucil
CN115887677B (zh) * 2022-11-03 2024-04-12 嘉兴学院 一种蛋白质仿生胶囊的制备方法和应用

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3265630A (en) * 1958-12-22 1966-08-09 Ncr Co Encapsulating lipophilic material by coacervation
US3265629A (en) * 1958-12-22 1966-08-09 Ncr Co Coating by phase separation
US3043782A (en) * 1958-12-22 1962-07-10 Upjohn Co Process for preparing a more impermeable coating by liquid-liquid phase separation
US3533958A (en) * 1966-07-22 1970-10-13 Ncr Co Process for making minute capsules
US3663685A (en) * 1968-04-01 1972-05-16 Minnesota Mining & Mfg Biodegradable radioactive particles
US3663686A (en) * 1968-04-24 1972-05-16 Minnesota Mining & Mfg Biodegradable radioactive particles
US3663687A (en) * 1968-06-26 1972-05-16 Minnesota Mining & Mfg Biodegradable parenteral microspherules
US3541201A (en) * 1968-12-18 1970-11-17 Ethan Alan Brown Novel sodium chloride encapsulated injectionable substances
US3937668A (en) * 1970-07-15 1976-02-10 Ilse Zolle Method for incorporating substances into protein microspheres

Also Published As

Publication number Publication date
FR2326934A1 (fr) 1977-05-06
DE2645553C2 (de) 1986-11-06
SE443086B (sv) 1986-02-17
CH629666A5 (de) 1982-05-14
AU1850676A (en) 1978-04-13
DE2645553A1 (de) 1977-04-21
AU513080B2 (en) 1980-11-13
CA1077842A (en) 1980-05-20
SE7611064L (sv) 1977-04-10
GB1567763A (en) 1980-05-21
US4147767A (en) 1979-04-03
JPS5247912A (en) 1977-04-16
FR2326934B1 (en:Method) 1979-07-20

Similar Documents

Publication Publication Date Title
JPH0133445B2 (en:Method)
AU656919B2 (en) Drug delivery vehicles suspended in nonaqueous perfluorinated carrier
US4847091A (en) Pharmaceutical composition including sodium cromoglycate
US6602524B2 (en) Microspheres for use in the treatment of cancer
US5275820A (en) Stable suspension formulations of bioerodible polymer matrix microparticles incorporating drug loaded ion exchange resin particles
Burgess et al. Potential use of albumin microspheres as a drug delivery system. I. Preparation and in vitro release of steroids
JPH06510772A (ja) 固体状脂質微粒子(固体状脂質ナノ球体)製の薬剤用キャリヤー
WO2000033820A2 (de) Nanopartikuläre kern-schale systeme sowie deren verwendung in pharmazeutischen und kosmetischen zubereitungen
JPH06508369A (ja) 薬剤用キャリヤーシステム
Motycka et al. Preparation and evaluation of microencapsulated ion-exchange resin beads
CN116603081B (zh) 一种可生物降解的放射性90y微球及其制备方法
JPH04507412A (ja) 薬学上の化合物
JPS6163613A (ja) 顆粒状に調整された徐放性製剤
Jain et al. Magnetically guided rat erythrocytes bearing isoniazid: preparation, characterization, and evaluation
Colombo et al. Effect of excipient composition on the biocompatibility of bupivacaine‐containing microparticles at the sciatic nerve
US2518510A (en) Stable injectable oil-pectin therapeutic compositions
US20070219127A1 (en) Cyclosporin a compositions
Kohane et al. pH-triggered release of macromolecules from spray-dried polymethacrylate microparticles
Vural et al. Cyclophosphamide loaded albumin microspheres II. Release characteristics
Parikh et al. Oestrone loaded poly (l-lactic acid) microspheres: preparation, evaluation and in vitro release kinetics
CN107982214A (zh) 兽用恩诺沙星固体脂质纳米混悬液及其制备方法
Meenega Innovative drug delivery using microsheric carriers
Onur et al. Decrease in the placental transfer of chloramphenicol when administered in albumin microspheres into rats
Samad et al. 20 Microsphere
JPS63501573A (ja) ナトリウムクロモグリケ−トを含有する医薬組成物