JPH01305078A - 新規なヘテロアロチノイド誘導体 - Google Patents

新規なヘテロアロチノイド誘導体

Info

Publication number
JPH01305078A
JPH01305078A JP1094306A JP9430689A JPH01305078A JP H01305078 A JPH01305078 A JP H01305078A JP 1094306 A JP1094306 A JP 1094306A JP 9430689 A JP9430689 A JP 9430689A JP H01305078 A JPH01305078 A JP H01305078A
Authority
JP
Japan
Prior art keywords
formula
group
compound according
pharmaceutically acceptable
derivative
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP1094306A
Other languages
English (en)
Japanese (ja)
Other versions
JPH0585550B2 (enExample
Inventor
Jean-Daniel Brion
ジャン―ダニエル　ブリオン
Baut Guillaume Le
ギュイローム　ル　バウ
Patrick Ducrey
パトリック　ドュクリィ
Sylvie Piessard-Robert
シルビー　ピサール―ロベール
Claude Cudennec
クロード　クデネック
Genevieve Seurre
ジュネビエブ　スウル
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Institut Servier de Medecine Translationnelle SARL
Original Assignee
ADIR SARL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by ADIR SARL filed Critical ADIR SARL
Publication of JPH01305078A publication Critical patent/JPH01305078A/ja
Publication of JPH0585550B2 publication Critical patent/JPH0585550B2/ja
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/58—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring other than with oxygen or sulphur atoms in position 2 or 4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrane Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
JP1094306A 1988-04-13 1989-04-13 新規なヘテロアロチノイド誘導体 Granted JPH01305078A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8804870A FR2630110B1 (fr) 1988-04-13 1988-04-13 Nouveaux derives heteroarotinoides, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR8804870 1988-04-13

Publications (2)

Publication Number Publication Date
JPH01305078A true JPH01305078A (ja) 1989-12-08
JPH0585550B2 JPH0585550B2 (enExample) 1993-12-07

Family

ID=9365267

Family Applications (1)

Application Number Title Priority Date Filing Date
JP1094306A Granted JPH01305078A (ja) 1988-04-13 1989-04-13 新規なヘテロアロチノイド誘導体

Country Status (16)

Country Link
US (1) US4975455A (enExample)
EP (1) EP0338895B1 (enExample)
JP (1) JPH01305078A (enExample)
AT (1) ATE80881T1 (enExample)
AU (1) AU610379B2 (enExample)
CA (1) CA1326674C (enExample)
DE (1) DE68902946T2 (enExample)
DK (1) DK179289A (enExample)
ES (1) ES2035598T3 (enExample)
FR (1) FR2630110B1 (enExample)
GR (1) GR3006480T3 (enExample)
IE (1) IE64357B1 (enExample)
NZ (1) NZ228716A (enExample)
OA (1) OA09114A (enExample)
PT (1) PT90261B (enExample)
ZA (1) ZA892716B (enExample)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2630111B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
US5686465A (en) * 1988-10-31 1997-11-11 Endorecherche Inc. Sex steroid activity inhibitors
US5395842A (en) * 1988-10-31 1995-03-07 Endorecherche Inc. Anti-estrogenic compounds and compositions
US5183827A (en) * 1989-09-19 1993-02-02 Allergan, Inc. Acetylenes disubstituted with a heteroaromatic group and a 2-substituted chromanyl, thiochromanyl or 1,2,3,4-tetrahydroquinolinyl group having retinoid-like activity
US5250547A (en) * 1991-08-29 1993-10-05 Syntex (U.S.A.) Inc. Benzopyran derivatives
US6060503A (en) * 1991-12-02 2000-05-09 Endorecherche, Inc. Benzopyran-containing compounds and method for their use
JPH0852659A (ja) * 1994-08-08 1996-02-27 Tousetsu Denki Kk バイス
US6586460B1 (en) 2001-04-02 2003-07-01 The Board Of Regents For Oklahoma State University Heteroarotinoids containing urea or thiourea linker

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58206567A (ja) * 1982-05-12 1983-12-01 エフ・ホフマン―ラ　ロシユ　アーゲー 複素環式化合物
JPS60178815A (ja) * 1984-02-24 1985-09-12 Rikagaku Kenkyusho 制癌剤

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4808597A (en) * 1983-07-05 1989-02-28 Pfizer Inc. Method for inhibiting the degradation of cartilage
US4826984A (en) * 1984-04-09 1989-05-02 The Board Of Regents For The Oklahoma Agricultural And Mechanical College Acting For And On Behalf Of Oklahoma State University Heteroarotinoid compounds as anticancer agents
FR2630111B1 (fr) * 1988-04-13 1990-07-27 Adir Nouveaux derives trieniques de structure chromenique, leur procede de preparation et les compositions pharmaceutiques qui les contiennent
FR2642065B1 (fr) * 1989-01-24 1991-05-24 Lipha Derives d'acides benzocycloalcenyl dihydroxy alcanoiques, procede de preparation et medicaments les contenant

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS58206567A (ja) * 1982-05-12 1983-12-01 エフ・ホフマン―ラ　ロシユ　アーゲー 複素環式化合物
JPS60178815A (ja) * 1984-02-24 1985-09-12 Rikagaku Kenkyusho 制癌剤

Also Published As

Publication number Publication date
DK179289D0 (da) 1989-04-13
US4975455A (en) 1990-12-04
CA1326674C (fr) 1994-02-01
ATE80881T1 (de) 1992-10-15
AU610379B2 (en) 1991-05-16
AU3265989A (en) 1989-12-21
EP0338895B1 (fr) 1992-09-23
GR3006480T3 (enExample) 1993-06-21
ZA892716B (en) 1989-12-27
OA09114A (fr) 1991-10-31
ES2035598T3 (es) 1993-04-16
DE68902946D1 (de) 1992-10-29
NZ228716A (en) 1990-11-27
DK179289A (da) 1989-10-14
EP0338895A1 (fr) 1989-10-25
PT90261B (pt) 1994-07-29
PT90261A (pt) 1989-11-10
FR2630110A1 (fr) 1989-10-20
JPH0585550B2 (enExample) 1993-12-07
IE64357B1 (en) 1995-07-26
FR2630110B1 (fr) 1990-07-27
DE68902946T2 (de) 1993-04-29
IE891161L (en) 1989-10-13

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