JP7828613B2 - 特定の遺伝子のＣｐＧメチル化の変化を利用した膀胱癌診断用組成物およびその使用 - Google Patents

特定の遺伝子のＣｐＧメチル化の変化を利用した膀胱癌診断用組成物およびその使用

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JP7828613B2
JP7828613B2 JP2022546378A JP2022546378A JP7828613B2 JP 7828613 B2 JP7828613 B2 JP 7828613B2 JP 2022546378 A JP2022546378 A JP 2022546378A JP 2022546378 A JP2022546378 A JP 2022546378A JP 7828613 B2 JP7828613 B2 JP 7828613B2
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methylation
bladder cancer
cpg
kcna3
nr2e1
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JP2023513039A (ja
JP2023513039A5 (https=
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チョ，サンレイ
ムン，ヤングホー
ハン，ジニル
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Gencurix Inc
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Gencurix Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • C12Q1/6886—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material for cancer
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6813—Hybridisation assays
    • C12Q1/6834—Enzymatic or biochemical coupling of nucleic acids to a solid phase
    • C12Q1/6837—Enzymatic or biochemical coupling of nucleic acids to a solid phase using probe arrays or probe chips
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/154—Methylation markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/156—Polymorphic or mutational markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/16—Primer sets for multiplex assays

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  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Analytical Chemistry (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Wood Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Hospice & Palliative Care (AREA)
  • Biophysics (AREA)
  • Oncology (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
JP2022546378A 2020-01-28 2021-01-28 特定の遺伝子のＣｐＧメチル化の変化を利用した膀胱癌診断用組成物およびその使用 Active JP7828613B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
KR1020200010053A KR102637032B1 (ko) 2020-01-28 2020-01-28 특정 유전자의 CpG 메틸화 변화를 이용한 방광암 진단용 조성물 및 이의 용도
KR10-2020-0010053 2020-01-28
PCT/KR2021/001154 WO2021154009A1 (ko) 2020-01-28 2021-01-28 특정 유전자의 CpG 메틸화 변화를 이용한 방광암 진단용 조성물 및 이의 용도

Publications (3)

Publication Number Publication Date
JP2023513039A JP2023513039A (ja) 2023-03-30
JP2023513039A5 JP2023513039A5 (https=) 2024-03-04
JP7828613B2 true JP7828613B2 (ja) 2026-03-12

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JP2022546378A Active JP7828613B2 (ja) 2020-01-28 2021-01-28 特定の遺伝子のＣｐＧメチル化の変化を利用した膀胱癌診断用組成物およびその使用

Country Status (6)

Country Link
US (1) US20230084248A1 (https=)
EP (1) EP4098755A4 (https=)
JP (1) JP7828613B2 (https=)
KR (1) KR102637032B1 (https=)
CN (1) CN115315530A (https=)
WO (1) WO2021154009A1 (https=)

Families Citing this family (4)

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Publication number Priority date Publication date Assignee Title
WO2023083348A1 (zh) * 2021-11-15 2023-05-19 武汉艾米森生命科技有限公司 用于食管癌诊断的甲基化检测试剂及试剂盒
CN116168761B (zh) * 2023-04-18 2023-06-30 珠海圣美生物诊断技术有限公司 核酸序列特征区域确定方法、装置、电子设备及存储介质
CN118230812A (zh) * 2023-12-15 2024-06-21 王姝瑶 一种精确筛查的基因检测方法
CN118147311B (zh) * 2024-05-13 2024-09-20 北京橡鑫生物科技有限公司 尿路上皮癌甲基化标志物试剂盒

Citations (6)

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JP2008506407A (ja) 2004-07-18 2008-03-06 エピゲノミクス アーゲー 乳房細胞増殖性疾患を検出するためのエピジェネティックな方法および核酸
JP2008522590A (ja) 2004-12-02 2008-07-03 エピゲノミックス アクチェンゲゼルシャフト 前立腺細胞増殖障害の予後に関連する遺伝子発現分析のための方法および核酸
JP2008538497A (ja) 2005-04-15 2008-10-30 エピゲノミクス アーゲー 細胞増殖性疾患分析のための方法および核酸
US20100151468A1 (en) 2007-04-11 2010-06-17 Manel Esteller Epigenetic biomarkers for early detection, therapeutic effectiveness, and relapse monitoring of cancer
JP2011528804A (ja) 2008-07-18 2011-11-24 オラジェニックス，インコーポレイテッド 結腸直腸癌の検出及び治療のための組成物
US20120101023A1 (en) 2009-04-20 2012-04-26 Erasmus University Medical Center Rotterdam Method of diagnosing bladder cancer

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US8399193B2 (en) * 2007-08-30 2013-03-19 City Of Hope DNA methylation biomarkers for lung cancer
EP2390371A1 (en) * 2007-11-30 2011-11-30 Genomictree, Inc. Diagnosis kit and chip for bladder cancer using bladder cancer specific methylation marker gene
EP2233590A1 (en) * 2009-01-28 2010-09-29 AIT Austrian Institute of Technology GmbH Methylation assay
US20130065228A1 (en) * 2011-06-01 2013-03-14 University Of Southern California Genome-scale analysis of aberrant dna methylation in colorectal cancer
US9096905B2 (en) * 2012-02-23 2015-08-04 Medical Diagnostic Laboratories, Llc Detecting DNA methylation of BCL2, CDKN2A and NID2 genes to predict bladder cancer in humans
KR101750146B1 (ko) * 2014-12-30 2017-06-23 충북대학교 산학협력단 방광암 예후 진단 마커로서 ｒｓｐｈ９의 용도
EP3640341B1 (en) * 2015-02-24 2022-07-27 Zymo Research Corporation Assays to determine dna methylation and dna methylation markers of cancer
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JP2008506407A (ja) 2004-07-18 2008-03-06 エピゲノミクス アーゲー 乳房細胞増殖性疾患を検出するためのエピジェネティックな方法および核酸
JP2008522590A (ja) 2004-12-02 2008-07-03 エピゲノミックス アクチェンゲゼルシャフト 前立腺細胞増殖障害の予後に関連する遺伝子発現分析のための方法および核酸
JP2008538497A (ja) 2005-04-15 2008-10-30 エピゲノミクス アーゲー 細胞増殖性疾患分析のための方法および核酸
JP2013090629A (ja) 2005-04-15 2013-05-16 Epigenomics Ag 細胞増殖性疾患分析のための方法および核酸
US20100151468A1 (en) 2007-04-11 2010-06-17 Manel Esteller Epigenetic biomarkers for early detection, therapeutic effectiveness, and relapse monitoring of cancer
JP2011528804A (ja) 2008-07-18 2011-11-24 オラジェニックス，インコーポレイテッド 結腸直腸癌の検出及び治療のための組成物
US20120101023A1 (en) 2009-04-20 2012-04-26 Erasmus University Medical Center Rotterdam Method of diagnosing bladder cancer

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Also Published As

Publication number Publication date
EP4098755A1 (en) 2022-12-07
JP2023513039A (ja) 2023-03-30
KR20210096509A (ko) 2021-08-05
KR102637032B1 (ko) 2024-02-15
US20230084248A1 (en) 2023-03-16
EP4098755A4 (en) 2024-06-26
WO2021154009A1 (ko) 2021-08-05
CN115315530A (zh) 2022-11-08

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