JP7780235B2 - 抗酸化化合物 - Google Patents

抗酸化化合物

Info

Publication number
JP7780235B2
JP7780235B2 JP2025535840A JP2025535840A JP7780235B2 JP 7780235 B2 JP7780235 B2 JP 7780235B2 JP 2025535840 A JP2025535840 A JP 2025535840A JP 2025535840 A JP2025535840 A JP 2025535840A JP 7780235 B2 JP7780235 B2 JP 7780235B2
Authority
JP
Japan
Prior art keywords
compound
solvate
reaction
radical
item
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
JP2025535840A
Other languages
English (en)
Japanese (ja)
Other versions
JPWO2025023252A1 (https=
Inventor
治 徳丸
伸二 宮本
明弘 樋口
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
NATIONAL UNIVERSITY CORPORATION OITA UNIVERSITY
Original Assignee
NATIONAL UNIVERSITY CORPORATION OITA UNIVERSITY
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NATIONAL UNIVERSITY CORPORATION OITA UNIVERSITY filed Critical NATIONAL UNIVERSITY CORPORATION OITA UNIVERSITY
Publication of JPWO2025023252A1 publication Critical patent/JPWO2025023252A1/ja
Application granted granted Critical
Publication of JP7780235B2 publication Critical patent/JP7780235B2/ja
Active legal-status Critical Current
Anticipated expiration legal-status Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/06—Free radical scavengers or antioxidants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/20—Unsaturated compounds containing keto groups bound to acyclic carbon atoms
    • C07C49/24—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups
    • C07C49/245—Unsaturated compounds containing keto groups bound to acyclic carbon atoms containing hydroxy groups containing six-membered aromatic rings
    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09K—MATERIALS FOR MISCELLANEOUS APPLICATIONS, NOT PROVIDED FOR ELSEWHERE
    • C09K15/00—Anti-oxidant compositions; Compositions inhibiting chemical change
    • C09K15/04—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds
    • C09K15/06—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing oxygen
    • C09K15/08—Anti-oxidant compositions; Compositions inhibiting chemical change containing organic compounds containing oxygen containing a phenol or quinone moiety

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Ophthalmology & Optometry (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Toxicology (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2025535840A 2023-07-24 2024-07-23 抗酸化化合物 Active JP7780235B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP2023119682 2023-07-24
JP2023119682 2023-07-24
PCT/JP2024/026351 WO2025023252A1 (ja) 2023-07-24 2024-07-23 抗酸化化合物

Publications (2)

Publication Number Publication Date
JPWO2025023252A1 JPWO2025023252A1 (https=) 2025-01-30
JP7780235B2 true JP7780235B2 (ja) 2025-12-04

Family

ID=94375332

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2025535840A Active JP7780235B2 (ja) 2023-07-24 2024-07-23 抗酸化化合物

Country Status (2)

Country Link
JP (1) JP7780235B2 (https=)
WO (1) WO2025023252A1 (https=)

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000319154A (ja) 1999-05-06 2000-11-21 Nippon Menaade Keshohin Kk 光毒性抑制剤
JP2005510503A (ja) 2001-10-25 2005-04-21 ノボゲン リサーチ ピーティーワイ リミテッド ６−ヒドロキシイソフラボン、誘導体及びそれを含む薬剤

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS57114509A (en) * 1981-01-07 1982-07-16 Eisai Co Ltd Remedy for diabetic cataract
JP4831454B2 (ja) * 2004-07-02 2011-12-07 独立行政法人産業技術総合研究所 皮膚外用剤

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2000319154A (ja) 1999-05-06 2000-11-21 Nippon Menaade Keshohin Kk 光毒性抑制剤
JP2005510503A (ja) 2001-10-25 2005-04-21 ノボゲン リサーチ ピーティーワイ リミテッド ６−ヒドロキシイソフラボン、誘導体及びそれを含む薬剤

Non-Patent Citations (2)

* Cited by examiner, † Cited by third party
Title
Journal of the Chemical Society，1965年01月01日，p.3040-3044
SAHIN, Kader et al.，Identifying the Novel Pyrimidine-Based CDK2 Inhibitors as Anticancer Agents Using Text-Mining and Co，Journal of the Turkish Chemical Society Section A: Chemistry，2020年06月23日，Vol.7, No.2，pages 383 to 404，https://dergipark.org.tr/tr/pub/jotcsa/issue/52506/701243

Also Published As

Publication number Publication date
JPWO2025023252A1 (https=) 2025-01-30
WO2025023252A1 (ja) 2025-01-30

Similar Documents

Publication Publication Date Title
WO2023104018A1 (zh) 取代的双环杂芳基化合物作为kras g12d抑制剂
JP5008258B2 (ja) 含硫黄ホスホリピド誘導体
AU2017254523A1 (en) Compounds and compositions for treating conditions associated with NLRP activity
CN112469697A (zh) 抗衰老组合物及其用途
CN110023311B (zh) 2-取代的氨基-萘并[1,2-d]咪唑-5-酮类化合物或其药学上可接受的盐
JP2003523975A (ja) 特異構造を持つ抗癌化合物群及びその生産方法
JP7041673B2 (ja) Ｎ－アシルエタノールアミド誘導体およびその使用
CN121085765A (zh) 用于预防和/或治疗线粒体疾病的组合物和方法
BR112014030325B1 (pt) Uso de composição contendo derivado de verbenona para a obtenção de produto destinado ao tratamento ou prevenção de doença cerebral degenerativa, alimento funcional para prevenir ou tratar doença neurodegenerativa e composto
KR20250110848A (ko) Sting 작용제로서 헤테로사이클릭 화합물
JP2026502514A (ja) アミノ脂質化合物およびその調製方法、ならびにその使用
CA3165209A1 (en) 2,5- or 2,6-disubstituted hydroquinone derivatives with at least one carboxy, sulfo or amido group useful as medicaments
JP7780235B2 (ja) 抗酸化化合物
CN108350023B (zh) 一种具有抗癌作用的化合物及其制备方法和应用
TW555558B (en) Freeze-dried composition containing glycosphingolipid and process for producing the same
CN117986237B (zh) 川芎嗪衍生物及其制备方法与用途
US20210300859A1 (en) Rosmarinic acid derivative or salt thereof
WO2025093058A1 (zh) 2-氧代吲哚啉类衍生物及其制备方法和应用
US20210346331A1 (en) Trpv4 activity inhibitor
JP6381605B2 (ja) 脳卒中治療用のイリドイド配糖体類化合物、その医薬組成物及びその使用方法
US20240115589A1 (en) Pharmaceutical composition for preventing cytokine storm
US11066378B2 (en) Caffeic acid derivatives for anti-angiogenesis
WO1990012800A1 (en) Phospholipid derivatives
CN116874485A (zh) 一种具有降血压作用的螺环化合物的制备及其用途
KR20230170141A (ko) 아마로우시아잔틴 a 에스테르 및 그의 용도

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20250527

TRDD Decision of grant or rejection written
A01 Written decision to grant a patent or to grant a registration (utility model)

Free format text: JAPANESE INTERMEDIATE CODE: A01

Effective date: 20251111

A61 First payment of annual fees (during grant procedure)

Free format text: JAPANESE INTERMEDIATE CODE: A61

Effective date: 20251114

R150 Certificate of patent or registration of utility model

Ref document number: 7780235

Country of ref document: JP

Free format text: JAPANESE INTERMEDIATE CODE: R150