JP7682813B2 - スルホニル尿素誘導体及びその使用 - Google Patents

スルホニル尿素誘導体及びその使用 Download PDF

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JP7682813B2
JP7682813B2 JP2021573382A JP2021573382A JP7682813B2 JP 7682813 B2 JP7682813 B2 JP 7682813B2 JP 2021573382 A JP2021573382 A JP 2021573382A JP 2021573382 A JP2021573382 A JP 2021573382A JP 7682813 B2 JP7682813 B2 JP 7682813B2
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alkyl
optionally substituted
disease
cycloalkyl
compound
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JP2022535956A5 (https=
JP2022535956A (ja
JPWO2020249667A5 (https=
Inventor
マーク ジー． ボック
デイビッド ハリソン
ジェーン イー． スカンロン
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ノッドセラ リミテッド
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/14—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D231/38—Nitrogen atoms
    • C07D231/40—Acylated on said nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2021573382A 2019-06-12 2020-06-11 スルホニル尿素誘導体及びその使用 Active JP7682813B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201962860663P 2019-06-12 2019-06-12
US62/860,663 2019-06-12
PCT/EP2020/066191 WO2020249667A1 (en) 2019-06-12 2020-06-11 Sulfonylurea derivatives and uses thereof

Publications (4)

Publication Number Publication Date
JP2022535956A JP2022535956A (ja) 2022-08-10
JP2022535956A5 JP2022535956A5 (https=) 2023-06-19
JPWO2020249667A5 JPWO2020249667A5 (https=) 2023-06-19
JP7682813B2 true JP7682813B2 (ja) 2025-05-26

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ID=71108563

Family Applications (1)

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JP2021573382A Active JP7682813B2 (ja) 2019-06-12 2020-06-11 スルホニル尿素誘導体及びその使用

Country Status (16)

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US (1) US12054461B2 (https=)
EP (1) EP3983387B1 (https=)
JP (1) JP7682813B2 (https=)
CN (1) CN114641466B (https=)
DK (1) DK3983387T3 (https=)
ES (1) ES2983661T3 (https=)
FI (1) FI3983387T3 (https=)
HR (1) HRP20240896T1 (https=)
HU (1) HUE067378T2 (https=)
LT (1) LT3983387T (https=)
PL (1) PL3983387T3 (https=)
PT (1) PT3983387T (https=)
RS (1) RS65711B1 (https=)
SI (1) SI3983387T1 (https=)
SM (1) SMT202400291T1 (https=)
WO (1) WO2020249667A1 (https=)

Families Citing this family (3)

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Publication number Priority date Publication date Assignee Title
GB201721185D0 (en) 2017-12-18 2018-01-31 Nodthera Ltd Sulphonyl urea derivatives
PL3983387T3 (pl) 2019-06-12 2024-08-19 NodThera Limited Pochodne sulfonylomocznika i ich zastosowania
KR102802013B1 (ko) * 2021-02-03 2025-05-07 환인제약 주식회사 알츠하이머병 치료를 위한 nlrp3 인플라마좀 소분자 억제제

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WO2019034686A1 (en) 2017-08-15 2019-02-21 Inflazome Limited NOVEL CARBOXAMIDE SULFONAMIDE COMPOUNDS
JP2019512009A (ja) 2016-02-16 2019-05-09 ザ・ユニバーシティ・オブ・クイーンズランド スルホニルウレアおよび関連化合物ならびにこれらの利用
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WO2019034686A1 (en) 2017-08-15 2019-02-21 Inflazome Limited NOVEL CARBOXAMIDE SULFONAMIDE COMPOUNDS
WO2020035464A1 (en) 2018-08-15 2020-02-20 Inflazome Limited Novel sulfonamideurea compounds

Also Published As

Publication number Publication date
DK3983387T3 (da) 2024-07-15
US12054461B2 (en) 2024-08-06
PT3983387T (pt) 2024-07-10
US20220227715A1 (en) 2022-07-21
SI3983387T1 (sl) 2024-09-30
FI3983387T3 (fi) 2024-07-09
RS65711B1 (sr) 2024-08-30
EP3983387B1 (en) 2024-04-24
PL3983387T3 (pl) 2024-08-19
SMT202400291T1 (it) 2024-09-16
CN114641466B (zh) 2025-09-30
ES2983661T3 (es) 2024-10-24
EP3983387A1 (en) 2022-04-20
HUE067378T2 (hu) 2024-10-28
HRP20240896T1 (hr) 2024-10-11
JP2022535956A (ja) 2022-08-10
CN114641466A (zh) 2022-06-17
LT3983387T (lt) 2024-07-25
WO2020249667A1 (en) 2020-12-17

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